Does management support drive sustained agile usage? a serial mediation model and cIPMA perspective. by Uthpala Wijesinghe, Vidara Mapitiyage, Chathurya Wickramarathne, Chamoda Wickramage, Krishantha Wisenthige, Chathuni Aluthwala

“…It pioneers in expounding the constructs' relative importance, performance and necessity, to offer actionable insights for agile practitioners. Finally, it provides methodological guidance to apply importance performance map analysis and necessary condition analysis in agile software development research.…”
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Grounded theory assessment of health needs in rural Mississippi Delta region, USA: Implications for health policy and management by Yalanda M. BARNER, Austine U. ONYIA, Russell L. BENNETT, Manoj SHARMA

“…Strategies to improve health outcomes in rural communities that emerged included: (1) improvement and practice of healthy habits, (2) provision of more healthcare facilities, (3) increase in access to quality of foods, and (4) increase in reliable transportation for the elderly population. To move research to action, it is necessary to engage community members directly and collaboratively in developing these strategies to address health disparities and other structural barriers that rural communities face regarding health and healthcare.…”
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From Natural Hosts to Agricultural Threats: The Evolutionary Journey of Phytopathogenic Fungi by Asanka Madhushan, Dulan Bhanuka Weerasingha, Evgeny Ilyukhin, Paul W. J. Taylor, Amila Sandaruwan Ratnayake, Jian-Kui Liu, Sajeewa S. N. Maharachchikumbura

“…Farming practices like mono-cropping resistant cultivars and prolonged use of fungicides with the same mode of action can drive the emergence of new pathotypes. …”
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Effects of Standardized Natural Citrus Extract on Growth, Gut Health, Carcass Quality, and Welfare of Broiler Chickens by Sekhou Cisse, Arkadiusz Matuszewski, Damian Bień, Patrycja Ciborowska, Anna Zalewska, Jakub Urban, Monika Michalczuk, Marta Mendel, Urszula Latek, Joanna Polak, Małgorzata Sobczak-Filipiak, Paweł Konieczka, Mohammed El Amine Benarbia

“…This study provides valuable insights into the mechanisms of action that may underlie the observed effects of SNCE on performance, as demonstrated in this study and others. …”
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Revealing novel protein interaction partners of glyphosate in Escherichia coli by Alix Sarah Aldehoff, Dominique Türkowsky, Patrick Lohmann, Masun Nabhan Homsi, Ulrike Rolle–Kampczyk, Elke Ueberham, Jörg Lehmann, Martin von Bergen, Nico Jehmlich, Sven–Bastiaan Haange

“…Yet, little is known about glyphosate’s interactions with other bacterial proteins or its broader modes of action at the proteome level. Here, we employed a quantitative proteomics and thermal proteome profiling (TPP) approach to identify novel protein binding partners of glyphosate in the E. coli proteome. …”
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Treatment with Herbal Formula Extract in the hSOD1G93A Mouse Model Attenuates Muscle and Spinal Cord Dysfunction via Anti-Inflammation by Eun Jin Yang, Sun Hwa Lee, Mudan Cai

“…Each bioactive component in such herbal combinations can exert a mechanism of action to increase therapeutic efficacy. Herein, we investigated the efficacy of an herbal formula, comprising Achyranthes bidentata Blume, Eucommia ulmoides Oliver, and Paeonia lactiflora Pallas, in suppressing the pathological mechanism of ALS in male hSOD1G93A mice. …”
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Numerical simulation study on the influence of bend diameter rate on the flow characteristics of nature gas hydrate particles by Yongchao Rao, Yunxiao Wang, Shuli Wang, Zijia Gong, Chenglong Zhang

“…Because the fluid flows into the pipe by spiral flow, the shear force inside the pipe is higher under the combined action of its tangential velocity at the pipe wall and the high speed zone inside the pipe wall. …”
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Clinical validation of explainable AI for fetal growth scans through multi-level, cross-institutional prospective end-user evaluation by Zahra Bashir, Manxi Lin, Aasa Feragen, Kamil Mikolaj, Caroline Taksøe-Vester, Anders Nymark Christensen, Morten B. S. Svendsen, Mette Hvilshøj Fabricius, Lisbeth Andreasen, Mads Nielsen, Martin Grønnebæk Tolsgaard

“…Abstract We aimed to develop and evaluate Explainable Artificial Intelligence (XAI) for fetal ultrasound using actionable concepts as feedback to end-users, using a prospective cross-center, multi-level approach. …”
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Effect of celecoxib and paracetamol on the functional state of the central nervous system, pain sensitivity, and physical endurance of rats with acute heat injury by P.O. Chuikova, S.Yu. Shtrygol’

“…Since the effectiveness of drugs for the treatment of thermal injuries has not been proven, the search for new thermoprotective agents with different mechanisms of action, in particular inhibitors of the arachidonic acid cascade, is urgent. …”
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Single-cell immunopathology of recurrent acute generalized exanthematous pustulosis associated with vancomycin by Eric M. Mukherjee, MD, PhD, Andrew Gibson, PhD, Matthew S. Krantz, MD, Rama Gangula, MS, Amy M. Palubinsky, PhD, Alan S. Boyd, MD, Jeffrey P. Zwerner, MD, PhD, Anna K. Dewan, MD, MS, Nontaya Nakkam, PhD, Katherine C. Konvinse, MD, PhD, Yueran Li, PhD, Ramesh Ram, PhD, Abha Chopra, PhD, Elizabeth J. Phillips, MD

“…AGEP-affected skin showed an inflammatory infiltrate with a TH17-like effector population, which may represent potentially actionable targets for therapeutic intervention. The presence of HLA-A∗32:01, a defined risk factor for vancomycin-induced drug reaction with eosinophilia and systemic symptoms, may indicate a shared predisposition, warranting further study.…”
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Myoelectric pattern recognition with virtual reality and serious gaming improves upper limb function in chronic stroke: a single case experimental design study by Maria Munoz-Novoa, Morten B. Kristoffersen, Katharina S. Sunnerhagen, Autumn Naber, Max Ortiz-Catalan, Margit Alt Murphy

“…Repeated assessments were performed using the Fugl-Meyer Assessment of Upper Extremity (FMA-UE), Action Research Arm Test (ARAT), grip strength, and kinematics of the drinking task at baseline, during, and post intervention. …”
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How much bilateral and multilateral climate adaptation finance is targeting the health sector? A scoping review of official development assistance data between 2009-2019. by Tilly Alcayna, Devin O'Donnell, Sarina Chandaria

“…We anticipate these results will support researchers in developing actionable research on health and climate finance and decision-makers in mobilizing funds to low-resource settings with high health sector adaptation needs.…”
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MUC5B regulates alterations in the immune microenvironment in nasopharyngeal carcinoma via the Wnt/β-catenin signaling pathway by Hongming Wang

“…Abstract Objective To screen potential differentially expressed genes related to immune function in nasopharyngeal carcinoma through an online database, and to verify their mechanism of action, so as to provide a reference for the diagnosis and treatment of nasopharyngeal carcinoma in the future. …”
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Mineralocorticoid axis activity and cardiac remodeling in patients with ACTH-dependent Cushing’s syndrome by Peter Wolf, Simon Travers, Oliver Domenig, Stephanie Baron, Anne Blanchard, Khaoula Bouazizi, Nadjia Kachenoura, Sylvie Salenave, Marko Poglitsch, Alban Redheuil, Severine Trabado, Jacques Young, Philippe Chanson, Peter Kamenický

“…Low levels of aldosterone in the presence of unchanged precursor metabolites indicate a direct inhibitory action of cortisol excess on the aldosterone synthase. …”
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Electrophysical Microwave Installation for Heat Treatment of Animal Slaughter Waste by Evgeny V. Voronov

“…., corona discharge, electric field, screen efficiency, generator power, installation performance, and energy costs. The complex action of electromagnetic radiation provided a continuous combined heat treatment, disinfection, and odor neutralization with reduced operating costs. …”
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CONDITION OF HORMONAL STATUS OF THE BODY IN WHITE RATS UNDER THE EXPOSURE TO SODIUM FLUORIDE by I.Yu. Bagmut, I.L. Kolisnyk, S.I. Kryzhna, A.V. Titkova, L.Yu. Svyrydenko

“…Disruption of the balance of hormones and functioning of the endocrine organs and systems entails profound changes in the metabolic processes and the immunobiological reactivity of the organism, weakening the action of the protective-adaptive mechanisms in maintaining the homeostatic function.…”
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Selective Vulnerability of the Cochlear Basal Turn to Acrylonitrile and Noise by B. Pouyatos, C. A. Gearhart, A. Nelson-Miller, S. Fulton, L. D. Fechter

“…Auditory function was monitored by recording distortion products, by compound action potentials, and by performing cochlear histology. …”
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Numerical Simulation of the Influence of Natural Fractures on Hydraulic Fracture Propagation by Song Yaobin, Lu Weiyong, He Changchun, Bai Erhu

“…The following results are obtained: (1) The numerical results agree with the experimental data, indicating that the RFPA2D-Flow software can be used to examine the hydraulic fracture propagation process under the action of natural fractures. (2) In the case of a low principal stress difference and low approach angle, the hydraulic fracture likely causes shear failure along the tip of the natural fracture. …”
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Microlearning beyond boundaries: A systematic review and a novel framework for improving learning outcomes by Wali Khan Monib, Atika Qazi, Rosyzie Anna Apong

“…Based on the findings, we maintain that microlearning is an instructional approach that delivers targeted, action-oriented, bite-sized content to achieve specific objectives within a short period, typically within a few seconds or minutes. …”
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Evaluating regional sustainable energy potential through hierarchical clustering and machine learning by Selen Avcı Azkeskin, Zerrin Aladağ

“…This study’s key contributions lie in integrating clustering and classification methods systematically and providing actionable insights into which renewable energy sources are most suitable for each cluster. …”
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