Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma by Wei An, Kai Zhang, Guangbing Li, Shunzhen Zheng, Yukun Cao, Jun Liu

“…Our study illustrated a new mechanism of action for HY-PDT and might throw light on the individualized precision therapy for cholangiocarcinoma patients.…”
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Functional interaction between receptor tyrosine kinase MET and ETS transcription factors promotes prostate cancer progression by Elisa Carouge, Clémence Burnichon, Martin Figeac, Shéhérazade Sebda, Nathalie Vanpouille, Audrey Vinchent, Marie‐José Truong, Martine Duterque‐Coquillaud, David Tulasne, Anne Chotteau‐Lelièvre

“…Thus, our results demonstrate for the first time in prostate cancer models a functional interaction between ETS transcription factors (ETV1 and ERG) and MET signalling that confers more aggressive properties and highlight a molecular signature characteristic of this combined action.…”
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Low-Frequency rTMS over Contralesional M1 Increases Ipsilesional Cortical Excitability and Motor Function with Decreased Interhemispheric Asymmetry in Subacute Stroke: A Randomized... by Ka Yan Luk, Hui Xi Ouyang, Marco Yiu Chung Pang

“…The MEP (paretic hand) and interhemispheric asymmetry, Fugl-Meyer motor assessment, Action Research Arm Test, and box and block test scores improved more in the experimental group than controls at T1 (p<0.05). …”
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SELECTION OF EQUIPMENTFOR PROCESSING ANCIENT GRAINS by V. Petrov, A. Aleksashin, S. Pozner

“…Technological schemes with different peeling machines (peeling machine with abrasive discs, with rubber shafts, centrifugal action, impact peelers using a vibropneumatic table and friction separator) were analyzed, which have their own characteristics in separating peeled grain from unpeeled. …”
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A new process for extracting vanadium by direct calcification using the heat of molten vanadium slag by Qu J.-W., Zhang T.-A., Lv G.-Z., Chen Y.

“…The effect of the cooling method, CaO addition, and reaction time on the phases of calcified vanadium slag was studied. Under the action of oxygen and CaO, the molten vanadium slag underwent calcification reaction to form acid-soluble calcium vanadate phase and the feasibility of its main chemical reaction was calculated by Factsage8.1. …”
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A socioecological taxonomy of determinants to colorectal cancer screening in black men: Insights from a mixed-methods systematic review by P.J. Zaire, E. Miller, A.P. Ewing, J. Hefner, K. Wright, L.H. Smith

“…Conclusions: Key themes and significant findings from the review provide actionable strategies for primary care teams. These include enhancing knowledge about CRC screening within the patient population, improving patient-provider interactions, and reducing barriers to accessing screening. …”
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The efficiency of the seismic isolating sliding belt under the impact of the most unfavourable earthquake accelerograms by O. V. Mkrtychev, S. R. Mingazova

“…The objective of the study is to assess the effectiveness of seismic isolation in the form of a sliding belt at the foundation level under the action of the most unfavourable earthquake accelerograms using a direct nonlinear dynamic method.Materials and methods. …”
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Inflammatory-Driven Angiogenesis in Bone Augmentation with Bovine Hydroxyapatite, B-Tricalcium Phosphate, and Bioglasses: A Comparative Study by Vlad M. Anghelescu, Ioana Neculae, Octavian Dincă, Cristian Vlădan, Claudiu Socoliuc, Mirela Cioplea, Luciana Nichita, Cristiana Popp, Sabina Zurac, Alexandru Bucur

“…In our study, significant angiogenesis is linked with a greater tissue formation, indicating that in bone engineering with the allografts we used, inflammation has more benefic effects, the catabolic action being exceeded by the tissue formation.…”
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Exploring the effects of Tianma Gouteng granules on L-NAME-induced hypertensive rats based on 16S rDNA gene sequencing and metabolomics by Li Cheng, Zhenyang Huang, Jiawei He, Xinyi Zhang, Jiangxue Di, Hanmei Jiang, Yi Liu

“…Aim of the study: We explored the mechanism of action of TG on hypertension by 16S rDNA gene sequencing and non-targeted metabolomics, verified the correlation between hypertension and intestinal flora, searched for potential markers of intestinal flora, and screened for the correlation between different flora and different metabolites, which facilitates a more scientific and reasonable guidance for the administration of TG. …”
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A two-sex model for the influence of heavy alcohol consumption on the spread of HIV/AIDS by Gigi Thomas, Edward M. Lungu

“…In contrast to the result in some HIVvaccination models [52], backward bifurcation in our modelis not removed by replacing the corresponding standard incidencefunction with a mass action incidence, but is removed by merging thetwo susceptible classes of the same sex into one, i.e., by ignoringacquisition of, and ongoing recovery from, heavy-drinking habitsamong the susceptible population.…”
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Gravitational odd-parity perturbation of a Horndeski hairy black hole: quasinormal mode and parameter constraint by Zhen-Hao Yang, Yun-He Lei, Xiao-Mei Kuang, Bin Wang

“…While in Horndeski gravity, the isospectrality between the odd and even parity perturbations is broken due to the scalar field, the odd perturbation equation can be simplified into a modified RW equation from the perturbed action. In this paper, we propose a new auxiliary field and tortoise coordinate to refine the modified RW equation in Horndeski gravity, and calculate the QNM frequencies of the odd perturbation of a specific hairy black hole. …”
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Synergism of d-limonene and temozolomide on migratory and apoptotic behaviors of human glioblastoma cell lines by Megha Gautam, Reema Gabrani

“…This study aims to assess the impact of combining DL with TMZ and explore its potential mechanism of action in U87MG and LN229 GBM cells. Methods: The effects of the combined treatment of DL and TMZ were assessed on various cellular aspects, including cell viability, anchorage-independent cell growth, and DNA damage. …”
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Factors affecting mental health service delivery from primary healthcare facilities of western hilly district of Nepal: a qualitative study by Madhusudan Subedi, Gaurav Devkota, Puspa Basnet, Bijay Thapa

“…Aim To explore factors at different socioecological levels that affect mental health service delivery from primary healthcare (PHC) facilities of Arghakhanchi district, a western hilly district of Nepal.Background Mental health service delivery has seen four transformational shifts from Alma Ata to Astana Declaration. Mental Health Gap Action Programme has facilitated the delivery of evidence-based interventions on mental, neurological and substance use disorders by non-specialised health workers in PHC settings as well as advocated scaling up of mental healthcare through integration of mental health in PHC.Methods A cross-sectional qualitative study was conducted in Arghakhanchi district of Nepal from July to August 2019 that collected information through face-to-face key informant interviews of 16 purposively selected participants using validated interview guidelines. …”
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Study of some features of the foreign countries special police units activities by М. О. Borovyk

“…The latter involves the acquisition of knowledge of mine action, techniques for using a radio station, techniques of forced entry into the building and release of hostages, skills of extreme control and techniques of aiming fire at the vehicle, scuba diving techniques and express interrogation methods. …”
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MECHANICAL CALCULATION OF FLEXIBLE WIRES WHEN THE CONCENTRATED FORCES ARE REPLACED BY A DISTRIBUTED LOAD by Yu. V. Bladyko

“…On behalf of a span without tension springs of insulators the action of concentrated loads on the wire is considered, an error is determined when replacing the concentrated forces with the one uniformly distributed along the span by the load. …”
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Peculiarities of Informing Parents about Mental Disorders of Their Minor Children by O. V. Petlenko, N. V. Gnidko

“…The difficulty is that most parents do not agree with the need to take action on their children with residual organic problems, hoping that the child will outgrow over time the minor symptoms, from their point of view, that are manifested now. …”
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Upaya Peningkatan Cakupan Pemeriksaan Inspeksi Visual Dengan Asam Asetat (Iva) Di Dinas Kesehatan Kota Solok by Ridholla Permata Sari, Abdiana Abdiana

“…Dalam pelaksanaan kegiatan penyuluhan IVA dan pelaksanaan pemeriksaan IVA ini digunakan Plan, Do. Check, dan Action (PDCA). Dari data yang didapatkan sekitar 88 % WUS tidak pernah memeriksakan diri ke Puskesmas, hal ini karena pengetahuan masyarakat yang cukup (58%).…”
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Potential Implementation of Social Forestry in Engaging Community Participation in Restoring Peatlands by Haris Gunawan, Dian Afriyanti

“…Some (local) practices enable community participation in managing peatlands by gaining benefits from several ecosystem services (case study in Sungai Beras, East Tanjung Jabung, Jambi), integrating with other forestry management nearby (case study in Protected Peat Forest Londerang, East Tanjung Jabung, Jambi), decreasing social conflict (case study in Beram Itam, West Tanjung Jabung, Jambi); while in Kepulauan Meranti, action research in agroforestry elicited that the awareness about the wise practices in managing timber product and non timber forest product is potential for social forestry practices. …”
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Respectful community engagement in health research with diverse im/migrant communities by M Ruth Lavergne, Shira Goldenberg, Mei-ling Wiedmeyer, Stefanie Machado, Samira Karsiem

“…We engage community members throughout the research process, from identifying research topics to knowledge exchange.Conclusion We found that these structures offer an accessible visual representation of the project’s commitments to community engagement, and the ways these commitments are demonstrated through values and action. Our training opportunities, colearning activities and knowledge exchange efforts also confirmed the accuracy of interpretation, prompted additional analysis to clarify or add depth to findings, and helped us identify additional research topics. …”
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Evaluation of an Information Flow Gain Algorithm for Microsensor Information Flow in Limber Motor Rehabilitation by Naiqiao Ning, Yong Tang

“…Compared with the classification results of the grid search optimized support vector machine, the optimized vector machine has a 7% higher recognition rate, reaching 85%. The action recognition classification method of myoelectric signals is combined with an upper limb rehabilitation training platform to verify the feasibility of using myoelectric signals for rehabilitation training. …”
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