Impact of a Visual-Auditory-Kinesthetic Model-Based Educational Package on Knowledge Regarding Stroke Among Security Guards in a Tertiary Care Teaching Hospital by Parul, Latha Venkatesan, Achal Srivastava, Manju AK Rajora

“…The VAK model-based educational package was effective in improving knowledge of security guards regarding signs, symptoms, risk factors, and action to be taken on any sign of stroke.…”
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Antimicrobial activity of Monascus purpureus-derived red pigments against Salmonella typhimurium, Escherichia coli, and Enterococcus faecalis by Islam I. Teiba, Islam Mamdouh, Mokhtar I. Yousef, Ahmed Hussein, Emad H. El-Bilawy

“…Scanning electron microscopy was employed to explore the mechanism of action of the red dye extract, highlighting its impact on bacterial plasma membrane permeability and its interference with cellular energy production. …”
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How and why a multifaceted intervention to improve adherence post-MI worked for some (and could work better for others): an outcome-driven qualitative process evaluation by Holly O Witteman, Laura Desveaux, Justin Presseau, Noah Michael Ivers, Marianne Saragosa, Kirstie Russell, Nicola McCleary, J-D Schwalm

“…Objectives To explore (1) the extent to which a multicomponent intervention addressed determinants of the desired behaviours (ie, adherence to cardiac rehabilitation (CR) and cardiovascular medications), (2) the associated mechanism(s) of action and (3) how future interventions might be better designed to meet the needs of this patient population.Design A qualitative evaluation embedded within a multicentre randomised trial, involving purposive semistructured interviews.Setting Nine cardiac centres in Ontario, Canada.Participants Potential participants were stratified according to the trial’s primary outcomes of engagement and adherence, resulting in three groups: (1) engaged, adherence outcome positive, (2) engaged, adherence outcome negative and (3) did not engage, adherence outcome negative. …”
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Resistance of compressed elements with small eccentricity taking into account actual height of the compressed concrete zone by I. T. Mirsayapov, G. T. Apkhadze

“…The proposed dependencies make it possible to determine the actual stress-strain state in normal sections of eccentrically compressed reinforced concrete elements under the action of small eccentricities of application of the longitudinal compressive force in the limit state.…”
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Protective effect of resveratrol on retinal damage in glaucoma: a systematic review and meta-analysis of preclinical studies by Feng Zhang, Feng Zhang, Tao Li, Junli Wan, Junli Wan, Lu Wang, Lu Wang, Wenmei Guo, Wenmei Guo, Yue Hu, Yue Hu, Hao Wang, Hao Wang, Wei Bian, Wei Bian

“…Its potential mechanism of action may involve the suppression of pro-inflammatory cytokine levels and cell apoptosis.DiscussionResveratrol emerges as a promising agent for mitigating glaucoma-related retinal damage. …”
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A synthetic cyclic peptide for promoting antigen presentation and immune activation by Jiahui Zhang, Harrison Y. R. Madge, Asmaa Mahmoud, Lantian Lu, Wanyi Wang, Wenbin Huang, Prashamsa Koirala, Jazmina L. Gonzalez Cruz, Wei Yang Kong, Sahra Bashiri, Ahmed O. Shalash, Waleed M. Hussein, Zeinab G. Khalil, James W. Wells, Istvan Toth, Rachel J. Stephenson

“…In this study, we assessed the function-immunogenicity relationship of the multi-component vaccine candidate (referred to as VC-13) to elucidate a mechanism of action. We identified a potential universal delivery platform, not only capable of adjuvanting different peptide epitopes (e.g., NS1 and 88/30 from group A Streptococcus, gonadotropin hormone releasing hormone [GnRH]), but also protein antigens (e.g., bovine serum albumin [BSA], receptor binding domain (RBD) of the SARS-CoV-2 protein responsible for COVID-19 infection [SARS-CoV-2 RBD]) and small molecular haptens (e.g., cocaine). …”
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Electrical impedance-based tissue classification for bladder tumor differentiation by Carina Veil, Franziska Krauß, Bastian Amend, Falko Fend, Oliver Sawodny

“…Abstract Including sensor information in medical interventions aims to support surgeons to decide on subsequent action steps by characterizing tissue intraoperatively. …”
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Development of a Novel Co-Amorphous Curcumin and L-Arginine (1:2): Structural Characterization, Biological Activity and Pharmacokinetics by Jose Antonio Mancillas-Quiroz, Miriam del Carmen Carrasco-Portugal, Karina Mondragón-Vásquez, Juan Carlos Huerta-Cruz, Juan Rodríguez-Silverio, Leyanis Rodríguez-Vera, Juan Gerardo Reyes-García, Francisco Javier Flores-Murrieta, Jorge Guillermo Domínguez-Chávez, Héctor Isaac Rocha-González

“…<b>Methods</b>: Stability, solubility and structural characterization of the CAC12 were carried out by spectrometry techniques and in vitro assays, whereas the antinociceptive and anti-inflammatory effects were evaluated by CFA or carrageenan models. The mechanism of action was determined by cytokine quantification, and pharmacokinetic parameters were obtained through UPLC-MS/MS. …”
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Forecasting the seasonal phenology of Agrotis ipsilon in Oregon grass seed and vegetable agroecosystems by Emma Slone, Jessica Green, Navneet Kaur, Darrin L. Walenta, Nicole P. Anderson, Casey Cruse, Seth J. Dorman, Seth J. Dorman

“…Regionally specific phenological models serve as a critical component of effective areawide pest management plans to inform the timing of pest monitoring and management action. Seasonal modeling of A. ipsilon phenology is complicated by their migratory behavior and limited knowledge of temperature-dependent development on affected crop hosts. …”
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Comparative antidepressant effects and safety of intravenous racemic ketamine, psilocybin and theta burst stimulation for major depressive disorder: A systematic review and network... by Itsuki Terao, Wakako Kodama

“…Additionally, IV ketamine may have an advantage in terms of rapid onset of action. The number of included studies is limited, especially for psilocybin, and therefore the current findings are preliminary, necessitating further accumulation of direct‐comparison RCTs.…”
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Complementary cognitive roles for D2-MSNs and D1-MSNs during interval timing by Robert A Bruce, Matthew Weber, Alexandra Bova, Rachael Volkman, Casey Jacobs, Kartik Sivakumar, Hannah Stutt, Youngcho Kim, Rodica Curtu, Kumar Narayanan

“…Together, our findings demonstrate that D2-MSNs and D1-MSNs had opposing dynamics yet played complementary cognitive roles, implying that striatal direct and indirect pathways work together to shape temporal control of action. These data provide novel insight into basal ganglia cognitive operations beyond movement and have implications for human striatal diseases and therapies targeting striatal pathways.…”
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Ecocultural Perspectives On Mental Well-being and Self-harmony Among Sports Science Students by Peng Song, Shaojie Wang, Bo Jiang, Lunan Zhao

“…By employing mixed-method analyses (SCL-90 and SCL-HA scales), we identify key predictors of psychological well-being and propose actionable strategies for enhancing mental health interventions tailored to this cohort. …”
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Genetic analysis and heterosis breeding of seed yield and yieldattributing traits in Indian mustard (Brassica juncea (L.) Czern & Coss.) by Sanghamitra Rout, Suvendu Kumar Roy, Rupsanatan Mandal, Saurav Singla, Mehdi Rahimi, Bijaya Sur, Naderla Umamaheswar, Moumita Chakraborty, Lakshmi Hijam, Sahanob Nath, Manoj Kanti Debnath, Tulsi Saran Ghimiray

“…The estimation of genetic components of variance underscored a predominant influence of non-additive gene action, especially in traits linked to yield. Specific combining ability (SCA) consistently surpassed general combining ability (GCA), underscoring the substantial role of non-additive genetic effects. …”
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Durable resistance or efficient disease control? Adult Plant Resistance (APR) at the heart of the dilemma by Rimbaud, Loup, Papaïx, Julien, Rey, Jean-François, Moury, Benoît, Barrett, Luke G., Thrall, Peter H.

“…However, the impact of partial efficiency and delayed mode of action of APR on the evolutionary and epidemiological outcomes of resistance deployment has never been tested. …”
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Identifying focus zones for the conservation and promotion of priority birds in Swiss farmland by Noëlle Klein, Antoine Adde, Adrienne Grêt‐Regamey, Antoine Guisan, Felix Herzog, Philippe Jeanneret, Sonja Kay

“…This can help to identify zones and regions for ecological promotion and set priorities for action within future agricultural policies.…”
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Micro-field of Verbal Plurality in Latin by Bohdan Cherniukh

“…Distributivity involves the performance of an action by one of a set of actants and, depending on the sphere of distribution of the situation.  …”
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Is the Family Health Center Professionals’ Knowledge Level About Child Abuse and Neglect Sufficent? A Comprehensive Field Study by Serdar Deniz, Muhammet Bayraktar, Tufan Nayir, Elçin Balcı, Feyza İnceoğlu

“…Results: Since the overall scale score of the study group was above 3, it (3.77 ± 0.36) was determined that the average score of the participants was sufficient. 46.2% (<i>n</i> = 231) of the group did not receive training on child neglect and abuse during their education, and 45.2% (<i>n</i> = 226) during their work. 95.8% stated that they paid attention to signs of abuse and neglect in children brought for examination and follow-up, while 83.4% stated that they had not encountered any cases in the last year. 42% (<i>n</i> = 210) of the group thought that the relevant authorities would not take the necessary action even if they observed signs of child neglect and abuse, while 37.4% (<i>n</i> = 187) stated that they did not know when and how to report. …”
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Oral Administration of Ethanol Extract of Myristica fragrans Elicited Hyperactivity, Anxiety and Reduced Dopamine Level in Rats by SUNDAY Abba, SUNDAY ABRAHAM MUSA, Abel Agbon, SUNDAY OLADELE, IBRAHIM Joseph Momoh, ENYINNA OGBONNA, OLUSEGUN Dare Omotosho

“… Objective: Myristica fragrans, a common kitchen spice, is reported to have psychoactive properties, producing hallucinations and fear. The psychoactive action is attributed to the presence of myristicin. …”
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Study on Dynamic Performance of Standard Sand Based on KTL Dynamic Triaxial Apparatus by Bo Li, Xiaofei Li, Xueyang Xing

“…During the whole vibration process, the axial strain of the sample can develop greatly in the tensile and compressive direction. Under the action of different cyclic stresses, the stress path of the soil sample tends to zero, and the rate of effective stress state varies greatly, indicating that the dynamic stress has a great influence on the dynamic liquefaction process of Fujian standard sand. …”
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Conformational landscape of soluble α-klotho revealed by cryogenic electron microscopy by Nicholas J. Schnicker, Zhen Xu, Mohammad Amir, Lokesh Gakhar, Chou-Long Huang

“…The ability of FGF23 to engage two KLA’s simultaneously raises a potential new mechanism of action for FGF23-mediated signaling by the membranous klotho.…”
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