Modulatory effects of rutin on the expression of cytochrome P450s and antioxidant enzymes in human hepatoma cells by Karakurt Sedar

“…The flavonoid rutin was investigated for its anti-carcinogen and protective effects as well as modulatory action on CYPs and phase II enzymes in human hepatocellular carcinoma cells. …”
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Study on dynamic mechanical properties of frozen weakly cemented rock under lateral constraint by Weiyu Li, Weiyu Li, Shizheng Fang, Ye Zhu, Guangming Li

“…Based on the actual working conditions, the dynamic mechanical behavior of this kind of rock under the combined action of multiple variables was studied. Based on the freezing temperature of the freezing method for shaft construction, the experimental temperature gradient was set at 25°C to −25°C. …”
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Simulating Performance of a Dual Angle Particle Monitor for Atmospheric Particulate Matter by Charles D. Litton, Aranya Venkatesh, Jill Andersen, Dömötör Gulyás, Sara Longo, Chris Bartley, Illah Nourbakhsh

“…Such a monitor, that is low-cost and easy to use, can provide information directly to the users so that they can be driven to action. In particular, low-income communities that are often impacted by poor air quality will be able to more affordably determine real-time ambient conditions and drive positive change by helping to identify pollution sources and appropriate mitigation measures.…”
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Increased population exposure to extreme droughts in Iberia due to 0.5 °C additional anthropogenic warming by Ana Russo, Virgílio A Bento, Andreia F S Ribeiro, Daniela C A Lima, João A M Careto, Pedro M M Soares, Renata Libonati, Ricardo M Trigo, Célia M Gouveia

“…By offering a comprehensive assessment of drought conditions and population exposure, this study informs decision-making and climate resilience strategies, emphasizing the need for immediate action to mitigate adverse impacts on ecosystems and human populations.…”
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Study on Variation of Surface Runoff and Soil Moisture Content in the Subgrade of Permeable Pavement Structure by Lijun Hou, Yuan Wang, Fengchun Shen, Ming Lei, Xiang Wang, Xiaochong Zhao, Shuling Gao, Abdullah Alhaj

“…As time continued, the soil moisture content quickly reached a saturated state and presented a stable infiltration situation under the action of gravity and the gradient of soil water suction. …”
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Short communication: Upregulation of hypoxia/reoxygenation-induced Shc3 by downregulated miR-455-5p, suppresses trophoblast invasion and is associated with placental inflammation a... by Hui-Zhi Gong, Jing Guan, Ying-Zi Pan, Hong-Juan Ding, Ai-Wu Shi, Ning Gu

“…Combining cell and molecular biology methods, we provide evidence of the function and mechanism of miR-455-5p action, and identify its potential target, Shc3, in PE. …”
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A new taxonomy of neuroprotective agents for stroke appropriate for the reperfusion era by Mersedeh Bahr-Hosseini, Jeffrey L. Saver

“…By focusing on broad physiologic targets of action rather than granular molecular mechanisms, this six-fold classification of neuroprotection can inform the design of preclinical studies and human clinical trials, including imaging biomarker endpoint selection and treatment timing. …”
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OPTIMIZING STUDENTS’ LOW FREQUENCY WORDS ACHIEVEMENT THROUGH IMPLEMENTING MODIFIED KEYWORD METHOD by Anjar Muttaqin

“…The research method used is class action research. The researcher conducts planning, implementation, observation and reflection during the research. …”
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Visualization of Observational Learning and Peer Influence on Plastic Waste Diversity in the Campus Environment Using ArcGIS by Nüket Sivri, Atilla Aydoğdu, Vildan Zülal Sönmez, Ceyhun Akarsu

“…Ultimately, the study emphasizes the need to support youth through various initiatives that exemplify ecological practices to encourage the adoption of sustainable solutions and urge authorities to take immediate action.…”
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Analysis of Unsteady Flow Characteristics of Centrifugal Pump under Part Load Based on DDES Turbulence Model by Tang Xin, Liu Zhili, Zhao Meng, Yang Haotian, Jiang Wei, Wang Yuchuan, Chen Diyi

“…Due to the asymmetric action of the volute, the radial velocity distribution law of flow channel C1 is different from other flow channels at different blade heights. …”
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Optimalisasi Peran Keluarga Melalui Edukasi dan Simulasi Terapi Relaksasi Autogenik sebagai Upaya Suportif Adaptif Pasien Stroke di Masyarakat by Israfil Israfil, Sarah Kartika Wulandari, I Ketut Swarjana, I Gede Putu Darma Suyasa, Ni Luh Putu Inca Buntari Agustini, Ida Ayu Ningrat Pangruating Diyu, Komang Ardidhana Nugraha Putra, Ni Luh Dwi Indrayani

“…Kegiatan dilaksanakan dengan metode edukasi dan simulasi dengan tahapan menggunakan pendekatan PARE (Preparation, Action, Reflection dan Evaluation). Sebanyak 100% peserta yang terlibat tidak mengetahui tentang terapi relaksasi autogenik. …”
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Operational Standard for Point-through-point Electroacupuncture Therapy of Traditional Chinese Medicine Rehabilitation Techniques by Working Group on Operational Standard for Point-through-point Electroacupuncture Therapy of Traditional Chinese Medicine Rehabilitation Techniques

“…Compared with conventional acupuncture, point-through-point electroacupuncture therapy has a wider scope of action and stronger acupuncture stimulation, resulting in the effects of dispersing meridians and clearing collaterals, promoting blood circulation and relieving pain and so on. …”
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Joint Optimization of RCC Gravity Dam on Complex Foundation Considering Seismic Dynamic Response by LI Jinyou, HU Jiang, GU Zhenhua

“…To explore the influence of transverse seam cutting of a high RCC gravity dam on the seismic performance of the dam body,this paper takes the RCC gravity dam project of Mahl Hydropower Station in Pakistan with high seismic intensity and sand-mudstone interbedded foundation as the research object.Through the establishment of three-dimensional integral finite element model,the self-compiled viscoelastic dynamic boundary program is introduced.The dynamic response and difference of the dam body under the design earthquake and maximum credible earthquake (MCE) conditions are calculated respectively when the code wave,site wave,and Koyna wave are input.Based on the ratio defined by the design formula of bearing capacity limit state,the seismic safety state of the RCC gravity dam is comprehensively evaluated by simulating the three comparison schemes of 1/3 height,2/3 height,and full joint cutting of transverse seam.The results show that when the code wave is input,under the action of MCE,the resistance effect ratio coefficient η of the dam foundation surface under the 1/3 and 2/3 height schemes of transverse seam cutting is greater than 1.Under the full joint scheme,η_min=0.91,and the values of η are less than 1 for a total of 6 times within 0.6 s.After comprehensive consideration,the 2/3 height of transverse seam cutting can be used as the construction recommendation scheme.The research results can provide a reference for the optimal layout of the RCC gravity dam project in the conditions of high seismic intensity and complex geology.…”
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Artificial Intelligence in Dyslexia Research and Education: A Scoping Review by Jia Rong Yap, Thirishankari Aruthanan, Mellisa Chin

“…Additionally, five significant challenges were identified: data quality and quantity, accessibility of artificial intelligence-powered support, bias and validity in assessments, balancing artificial intelligence assistance with human expertise, and transparency in artificial intelligence decision-making. Actionable steps are recommended to enhance dyslexia research and education to address these challenges. …”
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Geographic distribution and demographic factors associated with use of a long-acting reversible contraceptive (LARC) in Ethiopia by Mintesnot Tenkir Teni, Travis Loux, Ness Sandoval, Anne Sebert Kuhlmann

“…Methods: The 2019 Performance Monitoring For Action Ethiopia (PMA Ethiopia) survey data was used. …”
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Engineered ipilimumab variants that bind human and mouse CTLA-4 by Brett Robison, SJ Diong, Anusha Kumar, Thomas M. Moon, Olin Chang, Bryant Chau, Christine Bee, Ishita Barman, Arvind Rajpal, Alan J. Korman, Sean West, Pavel Strop, Peter S. Lee

“…These cross-reactive ipilimumab variants may facilitate improved translatability and future mechanism-of-action studies for anti-CTLA-4 targeting in murine models.…”
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Fault diagnosis and fault-tolerant control strategy for interleaved boost DC/DC converter dedicated to PEM fuel cell applications. by Belkheir Abdesselam, Amar Benaissa, Ouahid Bouchhida, Samir Meradi, Mohamed Fouad Benkhoris

“…The overall system has been simulated using MATLAB/Simulink software under different conditions such as reference voltage variation, load variation, and Short Circuit default ; the obtained  results in different phase demonstrate the higher  performance, of the proposed systems in terms of  dynamic performance, fast fault detection and fault tolerant action to restore the health stat. …”
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Deciphering the nature and statistical optimization of antimicrobial metabolites of two endophytic bacilli by Raghda S. Isleem, Ahmed M. Eid, Saad El-Din Hassan, Khaled M. Aboshanab, Ghadir S. El-Housseiny

“…Both bacterial isolates displayed antioxidant and antiviral activity and mild cytotoxic action. Genomic sequence and antiSMASH analysis showed that the biosynthetic gene clusters of bacillomycin, mycosubtilin, fengycin, and macrolactin H in B. velezensis CCASU-C6 and bacillibactin and Macrolactin H in B. subtilis CCASU-C11 showed 100% conservation.…”
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Entrepreneurial strategies for sustainable growth: a deep dive into cloud-native technology and its applications by T. A. Alka, Aswathy Sreenivasan, M. Suresh

“…The policymaker's and enterprises' focus and actionable intervention are necessary for developing mechanisms to solve the barriers of regulatory compliance, lack of skilled manpower, data security, privacy issues, and upfront investment for entrepreneurial success.…”
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Shaking Table Test on the Seismic Responses of a Slope Reinforced by Prestressed Anchor Cables and Double-Row Antisliding Piles by Zuo-ju Wu, Zhi-jia Wang, Jun-wei Bi, Xiao Fu, Yong Yao

“…At the potential sliding zone, the axial force of the anchor cable will increase suddenly under the action of earthquake; after the earthquake, the initial prestress of the anchor cable will be lost, with the loss range of 17.0%∼23.0%. …”
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