Myeloperoxidase and Eosinophil Peroxidase Inhibit Endotoxin Activity and Increase Mouse Survival in a Lipopolysaccharide Lethal Dose 90% Model by Robert C. Allen, Mary L. Henery, John C. Allen, Roger J. Hawks, Jackson T. Stephens

“…MPO and EPO enzymatic activities were not required for inhibition, and MPO haloperoxidase action did not increase endotoxin inhibition. Both MPO and EPO increased mouse survival in the LPS LD90 model. …”
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Triterpene esters from Uncaria rhynchophylla hooks as potent HIV-1 protease inhibitors and their molecular docking study by JiSuk Lee

“…Additionally, these interactions occur via π–anion and π–alkyl and alkyl hydrophobic interactions, which are responsible for the compound’s mode of action. These molecular docking studies strongly confirmed an excellent SAR. …”
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The mechanisms of efficacy and safety of Ginkgo biloba extract in acute ischemic stroke: a real-world study by Xiangqian Huang, Xiaoming Zhang, Jiahao Song, Duo Lan, Mengqi Wang, Xunming Ji, Da Zhou, Ran Meng

“…Conclusions The therapeutic effect of GBE in AIS may, in part, be attributed to its ability to enhance the antiplatelet action of aspirin, particularly in inhibiting AA-induced platelet aggregation. …”
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Nurses' Experiences of Communicating With Families in Municipal Home Health Care by Elisabeth Bruce, Susanna Pusa, Karin Sundin

“…Result Communication with families was viewed as a crucial action for building rapport to facilitate the involvement and support of families in difficult situations. …”
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Mesenchymal stem cells-derived exosomes attenuate mouse non-heart-beating liver transplantation through Mir-17-5p-regulated Kupffer cell pyroptosis by Yang Tian, Ming Jin, Nanwei Ye, Zhenzhen Gao, Yuancong Jiang, Sheng Yan

“…We found that miR-17-5p was significantly abundant in MSCs-Exo, targeting and regulating the TXNIP expression. This action inhibited NLRP3-mediated pyroptosis of Kupffer cells through the classical Caspase1-dependent pathway, alleviating DCD liver graft injury. …”
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Comparison of the Effectiveness and Mechanism of Effect of Acceptance and Commitment Therapy Based on Emotion-Focused Therapy on Sexual Health in Patients with Type 2 Diabetes: The... by Mojgan Zandi, Shahram Mohammad Khani, Mohammad Hatami

“…The Larson Sexual Satisfaction Questionnaire (LSSQ), Emotion Efficacy Scale (EES), and Acceptance and Action Questionnaire (AAQ) comprised the research instrument. …”
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Cinnamaldehyde impacts key cellular signaling pathways for induction of programmed cell death in high-grade and low-grade human glioma cells by Yoo Na Kim, Ketki Patil, S. Balakrishna Pai

“…Results The elucidation of the mechanism of action revealed the impact of CA on reactive oxygen species (ROS) levels. …”
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Dealing With the Complexity of Effective Population Size in Conservation Practice by Ancuta Fedorca, Joachim Mergeay, Adejoke O. Akinyele, Tamer Albayrak, Iris Biebach, Alice Brambilla, Pamela A. Burger, Elena Buzan, Ino Curik, Roberta Gargiulo, José A. Godoy, Santiago C. González‐Martínez, Christine Grossen, Myriam Heuertz, Sean Hoban, Jo Howard‐McCombe, Maria Kachamakova, Peter Klinga, Viktoria Köppä, Elenora Neugebauer, Ivan Paz‐Vinas, Peter B. Pearman, Laia Pérez‐Sorribes, Baruch Rinkevich, Isa‐Rita M. Russo, Adélaïde Theraroz, Nia E. Thomas, Marjana Westergren, Sven Winter, Linda Laikre, Alexander Kopatz

“…To address the challenges associated with estimating Ne for conservation purposes, the COST Action 18134, Genomic Biodiversity Knowledge for Resilient Ecosystems (G‐BiKE), organized an international workshop that met in August 2022 in Brașov, Romania. …”
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The relationship between autonomy, optimism, work engagement and organisational citizenship behaviour among nurses fighting COVID-19 in Wuhan: a serial multiple mediation by Yang Liu, Hui Zhang, Yi Zhao, Leiwen Tang, Jing Shao, Zhihong Ye, Dandan Chen, Ping Zou, Shuanghong Lin

“…The effects of optimism and work engagement suggest a potential mechanism of action for the autonomy–organisational citizenship behaviour linkage. …”
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Microbial proliferation deteriorates the corrosion inhibition capability, lubricity, and stability of cutting fluid by Yuanyuan Shen, Wenkai Zhang, Lili Wu, Yaohua Dong, Guoqiang Guo, Lihua Dong, Zhangwei Guo

“…The rolling and bridging action of the resulting fungal mycelium caused flocculation of the effective components in the cutting fluid, resulting in reduced lubricity and poor stability. …”
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Adverse Reactions due to the Usage Ofadverse Effects due to the Usage of T biomodulina and corticotropin in Patients Suffering from Multiple Sclerosis by Rosa F. Lara Rodríguez, Roman Rodríguez, Alicia Vargas Batista, Miriam Bolet Arostavista, Rebeca A. Fernández Carriera, Idalmis Suárez Luis, Alina González-Quevedo Monteagudo, Lorenzo Gómez Morales

“…<strong>Background:</strong> T biomodulina is a thymic natural product with anti-inflammatory and immunomodulator action. Corticotropin is a steroid which is also used in the treatment of multiple sclerosis. …”
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Theoretical frameworks for constructing a model for analysis of Islamic discourse on YouTube: one view from Serbia by Predrag Pavlićević

“…Designing a framework for understanding reality and through associated eschatology, the rules of everyday action, principles and limits of tolerance, and identity – especially through discursive strategies and argumentation and beliefs that establish enemies – Islamic discourse on YouTube interprets reality, constructs and impose the only possible reality, and the necessity of achieving the ideal universal Islamic perfection.…”
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Entre gouvernance locale et institutionnalisation des territoires by Vincent Andreu-Boussut, Claire Choblet

“…So, this article examines the mechanisms collective action gives rise to, as well as the articulation between the stakeholders’ strategies and social practices, not to mention the legitimacy of people’s intervention. …”
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HDAC1-3 inhibition triggers NEDD4-mediated CCR2 downregulation and attenuates immunosuppression in myeloid-derived suppressor cells by Zhiqi Xie, Jinjin Shao, Zeren Shen, Zhichao Ye, Yoshiaki Okada, Daisuke Okuzaki, Naoki Okada, Masashi Tachibana

“…Our findings reveal a novel mechanism of action of HDAC1-3 inhibitors in MDSCs and suggest a potential synergistic immunotherapy strategy for clinical benefit in HCC.…”
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Interpersonal networks and the archaeology of social structures; using social positioning events to understand social strategies and individual behaviour by Joaquim Carvalho, Rosário Campos

“…A central aspect of the methodology used is the concept of "event of relative social positioning": an action, traceable in the sources, by which an actor makes explicit his perception of his own social position relative to another actor. …”
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Effect of virtual interactions through avatar agents on the joint Simon effect. by Yuki Harada, Yoshiko Arima, Mahiro Okada

“…This effect has been considered to be influenced by the social factors of a partner: sharing stimulus-action representation. According to this account, virtual interactions through their avatars would produce the joint Simon effect even when the partner did not physically exist in the same space because the avatars are intentional agents. …”
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Current Perspectives on Treatment of Gram-Positive Infections in India: What Is the Way Forward? by Atul P. Kulkarni, Vasant C. Nagvekar, Balaji Veeraraghavan, Anup R. Warrier, Deepak TS, Jaishid Ahdal, Rishi Jain

“…The most important step is development of newer antimicrobial agents with novel mechanisms of action and favourable pharmacokinetic profile. This review provides a synopsis about the current burden, treatment options, and the challenges faced by the clinicians in the management of GPIs such as MRSA, Quinolone-resistant Staphylococcus, VRE, and drug-resistant pneumococcus in India.…”
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Effect of single ethanol administration on behavior and the consumption and preference of ethanol in tame and aggressive rats by R. V. Kozhemyakina, S. G. Shikhevich, A. Cagan, R. G. Gulevich

“…It pointed not only to the absence of an anxiolytic action of 12 % ethanol but also to enhancement of anxietylike behavior in tame rats. …”
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Investigating Neurometabolite Changes in Response to Median Nerve Stimulation by Mairi S. Houlgreave, Katherine Dyke, Adam Berrington, Stephen R. Jackson

“…ABSTRACT Background Rhythmic median nerve stimulation (MNS) at 10 Hz has been shown to cause a substantial reduction in tic frequency in individuals with Tourette syndrome. The mechanism of action is currently unknown but is hypothesized to involve entrainment of oscillations within the sensorimotor cortex. …”
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Identification of quantitative trait loci for yield traits and fine-mapping of qGW4 using the chromosome segment substitution line-Z708 and dissected single-segment substitution li... by Kai Zhou, Jinjin Yu, Zhaopeng Yu, Chunyu Chi, Jialin Ren, Zhuowen Zhao, Han Zhang, Yinghua Ling, Changwei Zhang, Fangming Zhao

“…Among them, qGW4, which controls wide grains, belongs to a single dominant gene action in S1 based on the frequency distribution of grain width and chi-square test analysis. …”
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