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9941
Data mining and socio-spatial patterns of COVID-19: geo-prevention keys for tackling the pandemic
Published 2021-12-01“…The main source is the daily records of micro-data on COVID-19 cases and the methodology is based on ESRI geo-technologies, and more specifically on a tool called SITAR (a Spanish acronym which stands for Fast-Action Territorial Information System). The main goal is to analyse and contribute to knowledge of the spatial patterns of COVID-19 at neighbourhood level from a space-time perspective. …”
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9942
Advances in Selenium and Related Compounds Inhibiting Multi-Organ Fibrosis
Published 2025-01-01“…This review delves into the latest research advancements in Se and Se-related biological agents for alleviating fibrosis in the heart, liver, lungs, and kidneys, detailing their mechanisms of action within fibrotic pathways. Additionally, the article summa-rizes some of the anti-fibrotic drugs currently in clinical trials for the aforementioned organ fibroses.Keywords: selenium, fibrosis, organ, clinical…”
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9943
Study of the effect of the introduction of mitochondrial import determinants into the gRNA structure on the activity of the gRNA/SpCas9 complex in vitro
Published 2020-08-01“…Meanwhile, the CRISPR/Cas9 system is fundamentally different from protein systems in that it is easy to use, highly efficiency and has a different mechanism of action. All the characteristics and capabilities of the CRISPR/Cas9 system make it a promising tool in mitochondrial genetic engineering. …”
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9944
Assessing antimicrobial use patterns in Christian Health Association of Malawi (CHAM) health facilities: A cross-sectional study protocol.
Published 2024-01-01“…These findings will inform the national antimicrobial stewardship action plan, aiming to safeguard the available antimicrobials.…”
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9945
Simulation study of pressure wave fluctuation law along fracture under water hammer effect
Published 2025-01-01“…The simulation results show that when the pulsating water flows at a certain flow rate in the fissure, the flow rate is hindered and reduced when it encounters the closure of the fissure end, and the water hammer effect occurs due to the superimposed reflection of inertia and pressure waves. Under the action of water hammer, the fluid pressure will jump instantaneously and hit the coal fissure in the form of rectangular pressure wave. …”
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9946
A Comprehensive Review of the Usefulness of Prebiotics, Probiotics, and Postbiotics in the Diagnosis and Treatment of Small Intestine Bacterial Overgrowth
Published 2025-01-01“…The further development of diagnostic methods, such as point of care testing (POCT) and portable devices, and a better understanding of the mechanisms of biotics action are needed to treat SIBO more effectively and improve the quality of life of patients.…”
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9947
Le corps du joueur et l’écran traversé : récurrences et circulation d’un motif.
Published 2018-12-01“…In this way, as depicted in numerous ads, the gaming situation is explicitly labeled as “action” and the player is thus often commanded to react. …”
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9948
Présentation de la nomenclature des préjudices réparables en cas d'atteintes à l'environnement
Published 2010-10-01“…This typology of the remediable environmental damage, which is being drafted on a participative basis, may be an operational instrument able to guide the different protagonists of environmental action (lawyers, magistrates, operators of polluting activities, insurers, environmental experts, environmental defenders…).…”
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9949
$$\hbox {H}_2$$ -roaming dynamics in the formation of $$\hbox {H}_{3}^{+}$$ following two-photon double ionization of ethanol and aminoethanol
Published 2025-01-01“…In contrast to previous studies, we additionally analyze a broad range of dissociative ionization products, which feature distinct dynamics from that of $$\hbox {H}_{3}^{+}$$ and allow initial insight into the action of the disruptive UV-probe pulse.…”
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9950
Function approximation method based on weights gradient descent in reinforcement learning
Published 2023-08-01“…Function approximation has gained significant attention in reinforcement learning research as it effectively addresses problems with large-scale, continuous state, and action space.Although the function approximation algorithm based on gradient descent method is one of the most widely used methods in reinforcement learning, it requires careful tuning of the step size parameter as an inappropriate value can lead to slow convergence, unstable convergence, or even divergence.To address these issues, an improvement was made around the temporal-difference (TD) algorithm based on function approximation.The weight update method was enhanced using both the least squares method and gradient descent, resulting in the proposed weights gradient descent (WGD) method.The least squares were used to calculate the weights, combining the ideas of TD and gradient descent to find the error between the weights.And this error was used to directly update the weights.By this method, the weights were updated in a new manner, effectively reducing the consumption of computing resources by the algorithm enhancing other gradient descent-based function approximation algorithms.The WGD method is widely applicable in various gradient descent-based reinforcement learning algorithms.The results show that WGD method can adjust parameters within a wider space, effectively reducing the possibility of algorithm divergence.Additionally, it achieves better performance while improving the convergence speed of the algorithm.…”
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9951
Toxicity of antimony in housefly after whole-life-cycle exposure: Changes in growth, development, redox homeostasis, mitochondrial function, and fecundity
Published 2025-01-01“…To elucidate the toxicity of Sb and its mechanism of action, this study aimed to investigate the adverse effects of Sb on a cosmopolitan insect, housefly (Musca domestica), under a whole life cycle (from embryonic to adult stage) exposure through the examination of a suite of parameters, including biological, physiological, behavioral, and molecular endpoints. …”
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9952
Focusing on the recent progress of tea polyphenol chemistry and perspectives
Published 2022-05-01“…More intensive research is warranted to elucidate the mechanisms of action underlying the biological activity of flavoalkaloids and the pharmacological application of tea polyphenols in scavenging RCS and impeding detrimental AGEs.…”
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9953
WORK POSTURE RELATIONS WITH LOW BACK PAIN COMPLAINT ON PARTNERS PART OF PT 'X' MANUFACTURE OF TOBACCO PRODUCTS
Published 2020-03-01“…Conclusion: From the work posture assessment that for workers who have medium and high risk Reba for immediate action such as repair of work stations and providing understanding of ergonomic work positions.…”
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9954
Evaluating the relationship between negative foot speed and sprint performance using shoe-mounted inertial sensors.
Published 2024-01-01“…In addition, the results of this study support the use of IMUs for quantifying sprinting technique with actionable metrics.…”
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9955
Par-delà le changement climatique, les représentations du changement environnemental : le poids de la tension entre filière et territoire dans les secteurs pastoral et viticole en...
Published 2016-12-01“…Additionally, the study critically engages with the main drivers through which public action is implemented in agriculture. Indeed, the paper stresses how relevant the organization of the productive sectors is (be it a local and place-based organization – pastoral sector ; or a more institutional and vertical one – wine production sector) in framing representations and strategies linked with environmental change.…”
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9956
Dificuldades e concepções de licenciandos em Matemática a respeito dos conceitos de dependência e independência linear
Published 2017-06-01“… Este artigo apresenta resultados de uma pesquisa que objetivou investigar dificuldades e concepções, segundo o aporte teórico APOS (action-process-object-schema), referentes aos conceitos de dependência e independência linear de licenciandos em Matemática. …”
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9957
Self-Healing Effect of Various Capsule-Core Materials on Asphalt Materials
Published 2022-01-01“…Finally, the bi-plate DSR test was applied to reveal the different action mechanisms between core materials and asphalt materials. …”
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9958
Long COVID in transgender and gender nonbinary people in the United States
Published 2025-01-01“…Abstract Despite recommendations in the US National Research Action Plan on Long COVID, gender identity is rarely reported in research and surveillance used to guide public health programming and clinical care. …”
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9959
Analysis on the Influence of Increasing Seismic Fortification Intensity on Seismic Performance of Underground Station
Published 2021-01-01“…By comparing the calculation results of the two seismic fortification intensity ground motion conditions, it is concluded that the connection between the side wall and the floor is the weakest position of the station structure under the action of the earthquake; the seismic fortification intensity is increased from VII to VIII to the internal force of the structure. …”
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9960
Neuropilin 1 Mediates Keratinocyte Growth Factor Signaling in Adipose-Derived Stem Cells: Potential Involvement in Adipogenesis
Published 2018-01-01“…Our study contributes to clarify the molecular bases of human adipogenesis, demonstrating a role of KGF in the early steps of this process, and points out a role of NRP1 as a previously unknown mediator of KGF action in ASCs.…”
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