The Effect of Lysophosphatidic Acid during In Vitro Maturation of Bovine Oocytes: Embryonic Development and mRNA Abundances of Genes Involved in Apoptosis and Oocyte Competence by Dorota Boruszewska, Ana Catarina Torres, Ilona Kowalczyk-Zieba, Patricia Diniz, Mariana Batista, Luis Lopes-da-Costa, Izabela Woclawek-Potocka

“…Our study demonstrates for the first time that bovine COCs are a potential source and target of LPA action. We postulate that LPA exerts an autocrine and/or paracrine signaling, through several LPARs, between the oocyte and cumulus cells. …”
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Pediatric patients clinical-epidemiological characterization with suicide attempt at the Holguín Provincial Pediatric Hospital by Nilda Ramona Sarmiento Ardebol, Jorge Antonio Fernández Carballo, Dayana María Fernández Sarmiento, Frank Miguel Hernández Velázquez

“…This group is very vulnerable to the action of internal and external factors that alter their integrity. …”
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IUPHAR review: Drug repurposing in Schizophrenia – An updated review of clinical trials by Jihan K. Zaki, Jakub Tomasik, Sabine Bahn

“…A notable development is the combination of the muscarinic modulators xanomeline, a compound with antipsychotic properties, and trospium, included to mitigate peripheral side effects, now approved by the FDA as the first antipsychotic drug in decades with a fundamentally novel mechanism of action. Moving beyond the traditional dopaminergic paradigm of schizophrenia, such findings highlight opportunities to improve treatment-resistant symptoms and alleviate adverse effects. …”
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Étude ethnotaxonomique des espèces fruitières spontanées comestibles chez l’ethnie Diola d’Oussouye (Sénégal) by Yves Djihounouck, Doudou Diop, César Bassène, Mame Samba Mbaye, Richard Demba Diop, Babacar Faye, Kandioura Noba

“…However, climate change and human action have led to a degradation of the natural ecosystems and extinction for certain plant. …”
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Ninety days of solitary confinement: Prison experience of the 'pervodumtsy' (First Duma deputies) convicted of signing the Vyborg Appeal by D.M. Usmanova, S.V. Shebalkov

“…As the result of the action carried out by the former deputies in Vyborg (Grand Duchy of Finland), 167 people were sentenced to 3 months of imprisonment and deprivation of the political rights. …”
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La Mission générale d’insertion de l’éducation nationale : des publics hétérogènes, une mission d’insertion ? by Pierre-Yves Bernard, Christophe Michaut

“…Depuis la création en 1984 du Dispositif d’insertion des jeunes de l’Education Nationale (DIJEN), le ministère inscrit explicitement dans son action une mission d’insertion. Celle-ci est définie au niveau académique, au sein d’un service rectoral, la MGI (Mission Générale d’Insertion). …”
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Progesterone Changes the Pregnancy-Induced Adaptation of Cardiomyocyte Kv2.1 Channels via MicroRNA-29b by Shuang Liang, Yu-Shuang Sun, Lu Li, Yao Long, Meng Wang, Hou-Zhi Yang, Chun-Di Li, Yan Wang, Shan-Shan Li, Xu Chen, Xin Jin

“…P4 administrations shortened the prolongation of QTC intervals and action potential duration (APD) that occurred during pregnancy, which was mainly attributable to the reduction in the voltage-gated potassium (Kv) current under basal conditions. …”
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Effect of a Traditional Chinese Herbal Medicine Formulation on Cell Survival and Apoptosis of MPP+-Treated MES 23.5 Dopaminergic Cells by Shuifen Ye, Ho Kee Koon, Wen Fan, Yihui Xu, Wei Wei, Chuanshan Xu, Jing Cai

“…Signaling proteins such as JAK2, STAT3, and ERK1/2 were also involved in the action of CRJ. Taken together, these results provide a preliminary mechanism to support clinical application of the TCM formulation in PD and possibly other neurodegenerative diseases associated with ROS injury and apoptosis.…”
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Defense responses of the green microalgae Chlorella vulgaris to the vanadium pentoxide nanoparticles by Kalehjahi Hanifeh Akbarian, Kosari-Nasab Morteza, Amini Mojtaba, Movafeghi Ali

“…Although, non-enzymatic antioxidant system in C. vulgaris displayed an average action, antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), and ascorbate peroxidase (APX) showed a dose dependent increasing trend. …”
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Numerical Analysis of Bearing Behavior of the Prebored Precast Pile with an Enlarged Base by Zao Ling, Jiangbin Wu, Weidong Wang

“…The transfer law of load among the precast pile, cement soil, and soil around the pile and the action mechanism of the enlarged base were analyzed emphatically, and a sensitivity analysis of the main factors affecting the bearing performance was carried out. …”
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Cathepsin G, a Neutrophil Protease, Induces Compact Cell-Cell Adhesion in MCF-7 Human Breast Cancer Cells by Tomoya Kudo, Hideaki Kigoshi, Takashi Hagiwara, Takahisa Takino, Masatoshi Yamazaki, Satoru Yui

“…Cathepsin G subsequently induced cell condensation, a very compact cell colony, resulting due to the increased strength of E-cadherin-mediated cell-cell adhesion. Cathepsin G action is protease activity-dependent and was inhibited by the presence of serine protease inhibitors. …”
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The microenvironment cell index is a novel indicator for the prognosis and therapeutic regimen selection of cancers by Xian-Yan Yang, Nian Chen, Qian Wen, Yu Zhou, Tao Zhang, Ji Zhou, Cheng-Hui Liang, Li-Ping Han, Xiao-Ya Wang, Qing-Mei Kang, Xiao-Xia Zheng, Xue-Jia Zhai, Hong-Ying Jiang, Tian-Hua Shen, Jin-Wei Xiao, Yu-Xin Zou, Yun Deng, Shuang Lin, Jiang-Jie Duan, Jun Wang, Shi-Cang Yu

“…Single-cell RNA sequencing (scRNA-seq), spatially resolved transcriptomics (SRT), and multiplex immunofluorescence (mIF) staining analyses verified MCI. The mechanism of action of the MCI was investigated in tumor-bearing mice. …”
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Optimality criteria for deterministic discrete-time infinite horizon optimization by Irwin E. Schochetman, Robert L. Smith

“…Our formulation allows for both discrete and continuous state and action spaces, as well as time-varying, that is, nonstationary, data. …”
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Foundational community factors: A local look at what and how neighborhoods matter for early childhood development in Quebec city, Canada by Alexandra Matte-Landry, Anne-Marie Rouillier, Nicolas R-Turgeon

“…These FCFs highlight leverage points and potential areas of action in the local context, as well as more broadly. …”
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« Ascénir » le space opera : de Joël Maillard à Bruno Latour by Danielle Chaperon

“…This questioning is rooted in the observation that this show shares with several other recent productions an apparently incongruous motif: touch down, namely the action of landing an aerospace vehicle on the ground of a planet. …”
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The mevalonate pathway contributes to breast primary tumorigenesis and lung metastasis by Javier Conde, Isabel Fernández‐Pisonero, L. Francisco Lorenzo‐Martín, Rocío García‐Gómez, Berta Casar, Piero Crespo, Xosé R. Bustelo

“…However, many issues remain obscure as yet regarding its mechanism of regulation and action. In the present study, we report that the expression of mevalonate pathway enzymes is mediated by the RHO guanosine nucleotide exchange factors VAV2 and VAV3 in a RAC1‐ and sterol regulatory element‐binding factor (SREBF)‐dependent manner in breast cancer cells. …”
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Leveraging machine learning and rule extraction for enhanced transparency in emergency department length of stay prediction by Waqar A. Sulaiman, Charithea Stylianides, Andria Nikolaou, Andria Nikolaou, Zinonas Antoniou, Ioannis Constantinou, Lakis Palazis, Anna Vavlitou, Theodoros Kyprianou, Theodoros Kyprianou, Efthyvoulos Kyriacou, Antonis Kakas, Antonis Kakas, Marios S. Pattichis, Andreas S. Panayides, Constantinos S. Pattichis, Constantinos S. Pattichis

“…By combining predictive analytics with interpretable rule-based methods, this research provides actionable insights for optimizing patient flow and resource allocation. …”
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Metabolic Activity of Micromycetes Affecting Urban Concrete Constructions by Galina Yakovleva, Eugene Sagadeev, Viktor Stroganov, Olga Kozlova, Rodion Okunev, Olga Ilinskaya

“…Concrete resistance to the destructive action of microorganisms is considered as a measure of its durability and is increasingly being raised as an important issue. …”
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The Ambit of Terms and Conditions of Employment in Equal Pay Claims Under Section 6(4) of the EEA: Lessons from International Labour Law by Shamier Ebrahim

“…It is clear from section 6(4) of the EEA that there are various elements that an equal pay claimant must prove across the three equal pay causes of action. The only element considered in this article is "[a] difference in terms and conditions of employment". …”
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Study of the neuronal response to olfactory stimuli in control and LPS-stimulated mice by functional magnetic resonance imaging by A. E. Akulov, A. V. Romashchenko, O. B. Shevelev, D. V. Petrovski, A. A. Savelov, M. P. Moshkin

“…Olfactory perception plays the key role in the inter­action of animals with biotic factors of the species-specific econiche. …”
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