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  1. 8601

    A systematic review of plant-based therapy for the management of diabetes mellitus in the East Africa community by Nancy Bonareri Mitaki, Ilemobayo Victor Fasogbon, Onyinye Vivian Ojiakor, Wusa Makena, Emmanuel O. Ikuomola, Reuben Samson Dangana, Ibe Micheal Usman, Ekom Monday Etukudo, Augustine Oviosun, Swase Dominic Terkimbi, Elizabeth Bessy Umoren, Angela Mumbua Musyoka, Solomon A Mbina, Esther Ugo Alum, Ibrahim Babangida Abubakar, Godson Emeka Anyanwu, Patrick Maduabuchi Aja

    Published 2025-02-01
    “…We extracted and analyzed information from the literature and showed that seven medicinal plants reduce blood sugar levels and insulin sensitivity through their mechanism of action. Conclusion: The phytochemical properties of these medicinal plants, mainly containing alkaloids, tannins, and flavonoids, may contribute to their hypoglycemic effects. …”
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  2. 8602

    Un programme d’éducation à l’environnement en RDC : la malle pédagogique « les grands singes et leur habitat », présentation des résultats d’une campagne de sensibilisation en pays... by Louis Ledo, Jean Christophe Bokika Ngawolo, Samy Mankoto, Richard Dumez, Sabrina Krief

    Published 2014-01-01
    “…Afin de mieux comprendre le contexte culturel du périmètre d’action de la malle en RDC et d’évaluer l’efficacité des messages de sensibilisations, des enquêtes mêlant questionnaires quantitatifs et entretiens semi-directifs ont été menées auprès de populations Batéké, du territoire de Bolobo (Province du Bandundu, RDC, février-juin 2011). …”
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  3. 8603

    The Equator Project Research School and Mentoring Network: Evaluated Interventions to Improve Equity in Geoscience Research by Natasha Dowey, Anya Lawrence, Munira Raji, Christopher Jackson, Rebecca Williams, Ben Fernando, Sam Giles, Jenni Barclay, Louisa Brotherson, Ethny Childs, Jacqueline Houghton, Anjana Khatwa, Keely Mills, George Jameson, Francisca Rockey, Steven Rogers, Catherine Souch

    Published 2024-12-01
    “…These interventions were co-created with and informed by the voices of students and professionals within the GEES community, following a Theory of Change-based, action research approach. The Equator Research School brought together 30 Black, Asian and minority ethnic students in GEES, and 12 academics, professionals and mentors, from across the UK for a 5-day residential workshop in April 2022. …”
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  4. 8604

    Spatiotemporal Variations in Phytoplankton Community Structure and Diversity: A Case Study for a Macroalgae–Oyster Reef Ecosystem by Min Xu, Qi Zhao, Yufu Xu, Shenzhi Wang, Yingbo Yu, Haipeng Zhang, Yun Wang, Jiabin Shen, Linlin Yang, Yunling Zhang, Takayoshi Otaki, Teruhisa Komatsu, Kaida Xu

    Published 2025-01-01
    “…., Ltd. constructed a 2 km<sup>2</sup> artificial oyster–macroalgae reef area by placing artificial reefs on the seabed adjacent to the Luanhe River Estuary. This action resulted in sustainable annual economic outputs through the fishing and sea cucumber put-and-take fishery. …”
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  5. 8605

    Characteristic of the active substance of the Saccharomyces cerevisiae preparation having radioprotective properties by G. S. Ritter, V. P. Nikolin, N. A. Popova, A. S. Proskurina, P. E. Kisaretova, O. S. Taranov, T. D. Dubatolova, E. V. Dolgova, E. A. Potter, S. S. Kirikovich, Y. R. Efremov, S. I. Bayborodin, M. V. Romanenko, M. I. Meschaninova, A. G. Venyaminova, N. A. Kolchanov, S. S. Bogachev

    Published 2020-10-01
    “…It was found that the injection of the RNA preparation at the time of maximum number of double-stranded breaks, 1 hour after irradiation, reduces the efficacy of radioprotective action compared with the injection 1 hour before irradiation and 4 hours after irradiation. …”
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  6. 8606

    Mamá Empoderada: study protocol for a pilot trial of a novel parenting and mental health prevention intervention for migrant mothers with young children at the Mexico-US border by Gudelia Rangel, Shira M Goldenberg, Eileen Pitpitan, Kaylee Ramage, Ietza Bojorquez-Chapela, Cecilia Martinez-Torteya, Katherine Rosenblum, Chelsie Hernandez, Monica Alvarez

    Published 2025-01-01
    “…The aim of this study is to pilot-test a novel parenting and mental health prevention intervention for migrant mothers with young children (MMC) in Tijuana, Mexico, including (a) assessing acceptability; (b) estimating effect sizes on symptoms of depression, anxiety, and parenting stress; (c) identifying which theory-based mechanisms of action predict changes in outcomes; and (d) identifying factors associated with differential intervention response.Methods and analysis ‘Mamá Empoderada’ (Mom Power) is a theory-based, trauma-informed group intervention to promote mental health and responsive parenting among mothers with young children (0–5 years). …”
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  7. 8607

    Plaider la « bonne gouvernance sécuritaire » au Maroc : Domestiquer les savoirs de réforme en régime de contrainte consensuelle by Irene Lizzola

    Published 2024-09-01
    “…In this register, the consensus is built around the reciprocal obligation to validate a legalist and managerial reformist discourse, strongly internationalized and deconflictualizing the issues, which unites the parties, as well as the mutual acceptance of the logics which accompany partnership selectivity governing the participation of associative and transnational actors in the “co-production” of public action. Here, the different actors play with these constraint factors, from the moment when each party benefits from the participation in the partnership dynamic. …”
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  8. 8608

    PATHOLOGICAL CHANGES IN MICE TREATED WITH CYCLOPHOSPHAMIDE AND EXOGENOUS DNA by E. V. Dolgova, V. P. Nikolin, N. A. Popova, A. S. Proskurina, K. E. Orishchenko, E. A. Alyamkina, Ya. R. Efremov, S. I. Baiborodin, E. R. Chernykh, A. A. Ostanin, S. S. Bogachev, T. S. Gvozdeva, E. M. Malkova, O. S. Taranov, V. A. Rogachev, A. S. Panov, S. N. Zagrebelnyi, M. A. Shurdov

    Published 2014-12-01
    “…The synergic action of the cytostatic drug cyclophosphamide (CP) and fragmented exogenous DNA causes illness and death in mice (Dolgova et al., 2011–2013). …”
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  9. 8609

    Injury characteristics, mechanisms, and game circumstances in junior community-level Australian football by Indianna L. Franke, Andrea B. Mosler, Brooke E. Patterson, Kay M. Crossley, Patrick Clifton, Steven McPhail, Mark J. Scholes, Matthew G. King

    Published 2025-06-01
    “…Objective: Describe the injury characteristics, game circumstances, and immediate action and management of injuries sustained by boys and girls participating in junior community Australian football. …”
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  10. 8610

    Recombinant Lactococcus lactis Carrying IL-4 and IL-10 Coding Vectors Protects against Type 1 Diabetes in NOD Mice and Attenuates Insulitis in the STZ-Induced Model by Tatiane M. Preisser, Vanessa P. da Cunha, Mariana P. Santana, Vanessa B. Pereira, Denise C. Cara, Bianca M. Souza, Anderson Miyoshi

    Published 2021-01-01
    “…Cytokines play a crucial role in the development of diabetes, orchestrating the recruitment and action of immune cells, to not only destroy insulin-producing cells but also preserve them. …”
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  11. 8611

    Roles for Prlhr/GPR10 and Npffr2/GPR74 in feeding responses to PrRP by Yi Wang, Weiwei Qiu, Stace Kernodle, Carly Parker, Marc-Antonio Padilla, Jiaao Su, Abigail J. Tomlinson, Stephanie Oldham, Joss Field, Elise Bernard, David Hornigold, Christopher J. Rhodes, David P. Olson, Randy J. Seeley, Martin G. Myers, Jr

    Published 2025-02-01
    “…While Prlhr plays a crucial role in the physiologic restraint of weight gain, the action of either receptor is capable of ameliorating obesity in response to enhanced NTSPrlh signaling.…”
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  12. 8612

    Call for Papers - Advancing Astropharmacy and Sports Pharmacy by Ashley Anderson, Ahmer Raza, Shireen Aziz, Misbah Noreen

    Published 2025-02-01
    “…She is actively working on addressing the challenges of medication stability in space and investigating the physiological effects of the space environment on drug metabolism and action. Misbah is also contributing to the advancement of the emerging field of Astropharmacy, collaborating with global experts to explore innovative pharmaceutical practices and regulatory frameworks for space missions. …”
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  13. 8613

    CWPO mechanism for toxic dye degradation in the presence of Cu@FbHAp catalyst: DFT study, performance analysis, response surface methodology, regeneration, and cost estimation by Youssef Miyah, Mohammed Benjelloun, Fatiha Mejbar, Salma Ssouni, Mohamed El-Habacha, Soulaiman Iaich, Noureddine El Messaoudi, Marouane Zerrouq, Mohammed Souilah, Anissa Lahrichi, Farid Zerrouq

    Published 2025-01-01
    “…The CWPO process mechanism is essentially based on the action of the 1 % Cu@FbHAp catalyst for hydrogen peroxide decomposition into reactive hydroxyl radicals that attack the chemical bonds of organic dyes, leading to their decolorization. …”
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  14. 8614

    Screening of <em>FecLL</em> prolific allele of the <em>B4GALNT2</em> gene in Algerian sheep populations by Assia Hadjazi, Fatima Zahra Belharfi, Fatima Zohra Mahammi, Stéphane Fabre, Semir Bechir Suheil Gaouar, Nacera Tabet-Aoul

    Published 2024-07-01
    “…The gene, FecL/B4GALNT2 (beta-1,4-N-acetyl-galactosaminyl transferase 2) and its prolific allele FecLL, which segregate in French Lacaune sheep and some local sheep breeds in Morocco and Tunisia, were found to influence ovarian function. However, their action differs from that of other major genes discovered previously, such as: FecX/BMP15 (bone morphogenetic protein 15); FecG/GDF9 (growth differentiation factor 9); and FecB/BMPR1B (bone morphogenetic protein receptor type 1B). …”
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  15. 8615

    Therapeutic applications of artemisinin in ophthalmic diseases by Hao Sun, Ping Zhao, Lianghui Zhao, Zhizhong Zhao, Haoyu Chen, Cong Ren, Bin Guo

    Published 2025-01-01
    “…To better explore and perfect the mechanism of action of artemisinin in ophthalmic diseases, and to better promote the clinical application of artemisinin, this study reviews the latest progress of artemisinin treatment for uveitis, uveal melanoma, age-related macular degeneration, diabetic retinopathy, ocular neovascularization, and dry eye, and it will provide theoretical support for the large-scale application of artemisinin in ophthalmic diseases in the future.…”
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  16. 8616

    Tau oligomers impair memory and synaptic plasticity through the cellular prion protein by Claudia Balducci, Franca Orsini, Milica Cerovic, Marten Beeg, Beatrice Rocutto, Letizia Dacomo, Antonio Masone, Eleonora Busani, Ilaria Raimondi, Giada Lavigna, Po-Tao Chen, Susanna Leva, Laura Colombo, Chiara Zucchelli, Giovanna Musco, Nicholas M. Kanaan, Marco Gobbi, Roberto Chiesa, Luana Fioriti, Gianluigi Forloni

    Published 2025-01-01
    “…In vitro and in vivo neuronal TauO exposure leads to synaptic and cognitive dysfunction, but their mechanisms of action are unclear. Evidence suggests that the cellular prion protein (PrPC) may act as a mediator of TauO neurotoxicity, as previously proposed for β-amyloid and α-synuclein oligomers. …”
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  17. 8617

    Functional interaction between receptor tyrosine kinase MET and ETS transcription factors promotes prostate cancer progression by Elisa Carouge, Clémence Burnichon, Martin Figeac, Shéhérazade Sebda, Nathalie Vanpouille, Audrey Vinchent, Marie‐José Truong, Martine Duterque‐Coquillaud, David Tulasne, Anne Chotteau‐Lelièvre

    Published 2025-02-01
    “…Thus, our results demonstrate for the first time in prostate cancer models a functional interaction between ETS transcription factors (ETV1 and ERG) and MET signalling that confers more aggressive properties and highlight a molecular signature characteristic of this combined action.…”
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  18. 8618
  19. 8619
  20. 8620

    Jianpi Yiqi Busui prescription alleviates myasthenia gravis by regulating Th17 through the TAK1/P38 MAPK/eIF-4E signaling pathway by Zhuming Chen, Jing Lu, Tianying Chang, Dongmei Zhang, Yibin Zhang, Miao Liu, Tong Wu, Peng Xv, Jian Wang

    Published 2025-02-01
    “…However, its mechanisms of action still require further clarification. In this study, an experimental autoimmune myasthenia gravis (EAMG) rat model was established for research. …”
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