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8421
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8422
Atiyah and Adams' sale of goods /
Published 2021Table of Contents: “…Sources of the law of sale of goods -- The contract of sale -- Subject-matter of the contract -- The types of obligation created -- The existence of the goods and the duty to pass a good title -- The duty to deliver the goods -- The duty to supply the goods at the right time -- The duty to supply goods in the right quantity -- The duty to supply goods od the right quality -- Exclusion of seller's liability -- The duties of the buyer -- The transfer of property -- Risk and frustration -- Transfer of title by a non-owner -- Export sales -- International Convention on Sales of Goods ("CISG") -- Real remedies -- Personal remedies -- Rejection of the goods, rescission, and specific performance -- Action for damages -- Consumer sales contracts -- Product liability -- Manufacturers' guarantees.…”
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8423
CD44-Receptors-Mediated Multiprong Targeting Strategy Against Breast Cancer and Tumor-Associated Macrophages: Design, Optimization, Characterization, and Cytologic Evaluation
Published 2025-01-01“…In this research, we aimed to design a multiprong targeting strategy for concurrent action against different phenotypes of BC (MCF-7 and SK-BR-3) and tumor-associated macrophages (TAMs) for relapse-free treatment of BC.Methods: Paclitaxel (PTX) and tamoxifen (TMX) co-loaded chitosan (CS) nanoparticles (NPs) were prepared using the ionic-gelation method and optimized using the Design Expert® software by controlling different material attributes. …”
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8424
Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model
Published 2025-02-01“…Abstract Background Neutrophil granulocytes are important parts of the defence against bacterial infections. Their action is a two-edged sword, the mediators killing the intruding bacteria are at the same time causing tissue damage. …”
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8425
Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance
Published 2025-01-01“…This study aims to clarify the anti-liver fibrosis effect of QgYp and its mechanism of action.MethodsThis study uses a carbon tetrachloride (CCl4) induced HF rat model and TGF-β1 stimulated HSC-T6 cell line (rat HSCs) as experimental models. …”
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8426
Heart Rate in Hypertension: Review and Expert Opinion
Published 2019-01-01“…Preference should be given to newer beta-blockers which reduce HR and both peripheral and central blood pressure to derive comprehensive advantage of this dual action. (ix) It still remains unclear whether reducing HR in HTN without comorbidities alters the CV and mortality outcomes.…”
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8427
Inhaled [D-Ala2]-Dynorphin 1-6 Prevents Hyperacetylation and Release of High Mobility Group Box 1 in a Mouse Model of Acute Lung Injury
Published 2021-01-01“…In this study, we demonstrate that inhaled [D-Ala2]-dynorphin 1-6 (leytragin), a peptide agonist of δ-opioid receptors, significantly inhibits HMGB1 secretion in mice with lipopolysaccharide- (LPS-) induced acute lung injury. The mechanism of action involves preventing HMGB1’s hyperacetylation at critical lysine residues within nuclear localization sites, as well as promoting the expression of sirtuin 1 (SIRT1), an enzyme known to deacetylate HMGB1. …”
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8428
Fabrication and In Vivo Evaluation of In Situ pH-Sensitive Hydrogel of Sonidegib–Invasomes via Intratumoral Delivery for Basal Cell Skin Cancer Management
Published 2024-12-01“…The problems with SDB’s low solubility, poor bioavailability, resistance, poor targeting, and first-pass action make it less effective when taken orally. This investigation set out to design an intratumoral in situ pH-sensitive hydrogel of SDB-invasomes (IPHS-INV) that can effectively treat BCSC by improving SDB’s bioavailability, sustainability, targeting, and efficacy while also reducing its resistance and undesirable side effects. …”
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8429
Circulating MicroRNAs in Patients with Psoriasis Treated with Anti-IL-23: A Cohort Study
Published 2025-01-01“…Overall, these results provide new insights into the mechanisms of risankizumab action and highlight miRNAs as promising candidates for personalized medicine approaches in psoriasis management.…”
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8430
Cultural revitalization for tourism development from an Indigenous perspective: the case of Ta Oi people, A Luoi District, Thua Thien Hue province, Vietnam
Published 2025-01-01“…These practices have been adapted to fit the modern context, demonstrating that cultural revitalization is not about restoring traditions in a static form but rather reconstructing them to meet evolving societal and economic demands.DiscussionThe research illustrates the adaptability and creativity of local people in preserving and revitalizing traditional culture, along with their enthusiasm and willingness to take action. Cultural preservation is not a top-down process; instead, it is co-created by the Indigenous community itself, shaped by differing viewpoints between elder and younger generations. …”
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8431
Efecto de la adición mineral cal- zeolita sobre la resistencia a la compresión y la durabilidad de un hormigón Effect of lime- zeolite binder on compression strength and durability...
Published 2009-08-01“…The results obtained prove the possibility to carry out the partial replacement of high volumes of OPC by lime - zeolite binder, without affecting the values of compression strength required and their behavior before action of the chloride ion penetration and the carbonation.…”
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8432
Silver Trimolybdate (Ag2Mo3O10.2H2O) Nanorods: Synthesis, Characterization, and Photo-Induced Antibacterial Activity under Visible-Light Irradiation
Published 2022-01-01“…This nanostructure presented a variable antibiotic-modulating action, which was not improved by visible LED light exposure. …”
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8433
Targeted protein degradation through site-specific antibody conjugation with mannose 6-phosphate glycan
Published 2024-12-01“…Recent developments in targeted protein degradation have provided great opportunities to eliminating extracellular protein targets using potential therapies with unique mechanisms of action and pharmacology. Among them, Lysosome-Targeting Chimeras (LYTACs) acting through mannose 6-phosphate receptor (M6PR) have been shown to facilitate degradation of several soluble and membrane-associated proteins in lysosomes with high efficiency. …”
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8434
Revealing novel protein interaction partners of glyphosate in Escherichia coli
Published 2025-01-01“…Yet, little is known about glyphosate’s interactions with other bacterial proteins or its broader modes of action at the proteome level. Here, we employed a quantitative proteomics and thermal proteome profiling (TPP) approach to identify novel protein binding partners of glyphosate in the E. coli proteome. …”
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8435
Influence of the A3669G Glucocorticoid Receptor Gene Polymorphism on the Metabolic Profile of Pediatric Patients with Congenital Adrenal Hyperplasia
Published 2014-01-01“…This study provides new insight into the GR screening during CAH treatment, which could help to identify the subgroup of at-risk patients who would most benefit from preventive therapeutic action.…”
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8436
Mesenchymal Stem Cells Ameliorate Hepatic Ischemia/Reperfusion Injury via Inhibition of Neutrophil Recruitment
Published 2018-01-01“…Mesenchymal stem cells (MSCs) have been shown to be immunomodulatory cells and have the therapeutic action on IRI in several organs. However, the mechanism of regulatory effect of MSCs on IRI remains unclear. …”
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8437
Standards in Neurological Rehabilitation, June 1997
Published 1997-01-01“…We firmly endorse international co-operation in this field and are happy to co-operate with any international organization in order to develop such links for clinical, educational or research initiatives. (8) The Task Force encourages individual countries to produce a document summarizing their own situation with regard to these standards and to produce a timetable for action to improve their situation. The EFNS Task Force would be pleased to assist in the publication of such deliberations or to act as a focus for international education and research or for sharing of examples of good practice.…”
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8438
Retinal Protection of New Nutraceutical Formulation
Published 2025-01-01“…<b>Results:</b> Among the nutraceutical formulations tested, only Epicolin showed a significant neuroprotective effect on SH-SY5Y attributable to the synergistic action of its single ingredients. As for antioxidant and scavenging activity, Epicolin showed a higher efficacy compared to FG and FN. …”
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8439
Internal Facilitation by Health Assistants for the “WHO Lay Health Worker Dementia Care” in Rural Uganda: A Formative Evaluation
Published 2025-02-01“…The integrated Promoting Action on Research Implementation in Health Services (i-PARIHS) framework guided data collection and analysis, focusing on implementation support, process improvement, and practice sustainment.Results: Strong support was found for health assistants’ roles in facilitating lay health worker-led dementia care at the community level. …”
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8440
Tunable structuring of nanocellulose-based sustainable lubricants by an external electric field
Published 2025-01-01“…The highest pre-shear yielded a structural break which, under the action of an electric voltage, enabled the formation of a different structural conformation when pre-shear halted, in comparison with the lowest pre-shear. …”
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