Hemoglobin-Derived Antioxidant Peptides from Beef Cattle in Ningxia: Identification Based on Computerized Screening and Molecular Docking by XU Feiran, WANG Yu, WANG Xiaojing, CUI Wei, WANG Yongkun, ZHOU Hui, WANG Zhaoming, CAI Kezhou, ZHANG Bao, XU Baocai

“…The potential antioxidant peptides were selected by computerized analysis and their activities were verified. Their action mechanism was studied by molecular simulation. …”
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Multi-study fMRI outlooks on subcortical BOLD responses in the stop-signal paradigm by Scott Isherwood, Sarah A Kemp, Steven Miletić, Niek Stevenson, Pierre-Louis Bazin, Birte Forstmann

“…This study investigates the functional network underlying response inhibition in the human brain, particularly the role of the basal ganglia in successful action cancellation. Functional magnetic resonance imaging (fMRI) approaches have frequently used the stop-signal task to examine this network. …”
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What are healthcare providers’ understandings and experiences of compassion? The healthcare compassion model: a grounded theory study of healthcare providers in Canada by Aynharan Sinnarajah, Shane Sinclair, Thomas F Hack, Shelley Raffin-Bouchal, Susan McClement, Kelli Stajduhar, Pavneet Singh, Neil A Hagen, Harvey Max Chochinov

“…Compassion was conceptualised as—a virtuous and intentional response to know a person, to discern their needs and ameliorate their suffering through relational understanding and action.Conclusions An empirical foundation of healthcare providers’ perspectives on providing compassionate care was generated. …”
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Not uni-dimension! Exploring the multi-dimensional concept of positive body image in the Chinese context by Hanqin Yan

“…With a positive psychology perspective, and based on the holistic positive body image theory, this study explored the multi-dimensional concept of positive body image in the Chinese context, integrated its three measures, examined the overall level of positive body image among Chinese college students, and tested the gender measurement invariance, as well as explored the latent categories of positive body image in the college student population.MethodsA convenience sampling method was used to survey 670 college students in China, using the Chinese version of Body Appreciation Scale-2 (BAS-2), Functionality Appreciation Scale (FAS), Body Image Acceptance and Action Questionnaire-5 (BI-AAQ-5), and the Positive Body Talk Scale (PBTS). …”
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Equipping our public health nutrition workforce to promote planetary health: a case example of tertiary education co-designed with students by Ka Po Chau, Wing Chong, Raquel Londono, Beau Cubillo, Julia McCartan, Liza Barbour

“… Abstract Objective: The public health nutrition workforce is well placed to contribute to bold climate action; however, tertiary educators are seeking practical examples of how to adequately prepare our future workforce. …”
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Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma by Wei An, Kai Zhang, Guangbing Li, Shunzhen Zheng, Yukun Cao, Jun Liu

“…Our study illustrated a new mechanism of action for HY-PDT and might throw light on the individualized precision therapy for cholangiocarcinoma patients.…”
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Examination of the Relationship between Psychosocial Mediators and Intervention Effects in It’s Your Game: An Effective HIV/STI/Pregnancy Prevention Intervention for Middle School... by Elizabeth Baumler, Jill Glassman, Susan Tortolero, Christine Markham, Ross Shegog, Melissa Peskin, Robert Addy, Heather Franks

“…This study suggests that the underlying causal mechanisms of action of these interventions are complex and warrant further analyses.…”
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HBV Core Promoter Inhibition by Tubulin Polymerization Inhibitor (SRI-32007) by Raj Kalkeri, Junzhong Peng, Chunsheng Huang, Zhaohui Cai, Roger G. Ptak, Mark J. Suto

“…Additional mechanism of action studies demonstrated potent inhibition of HBV core promoter activity by SRI-32007 with an EC50 of 40 nM and SI of >250. …”
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Extracecellulr vesicles (EVs) microRNAs (miRNAs) derived from mesenchymal stem cells (MSCs) in osteoarthritis (OA); detailed role in pathogenesis and possible therapeutics by Seyede Sara Pakdaman Kolour, Saeide Nematollahi, Masoud Dehbozorgi, Farnaz Fattahi, Fatemeh Movahed, Neda Esfandiari, Mohammad Saeed Kahrizi, Nima Ghavamikia, Bahareh Salmanian Hajiagha

“…Thus, the biosynthesis, chemical makeup, and mechanism of action of miRNAs-enriched EVs in OA are all thoroughly covered in this review. …”
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Thermally Conductive Shape-Stabilized Phase Change Materials Enabled by Paraffin Wax and Nanoporous Structural Expanded Graphite by Yilin Zhao, Shuhui Huang, Zhaoguo Jin, Zhongnan Xie, Hong Guo, Haofeng Xie

“…The expanded graphite formed a nanoscale porous structure by different methods, which enhanced the capillary action between the graphite flake layers, improved the adsorption and encapsulation of EG, and alleviated the leakage problem. …”
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miR-223 promotes cartilage differentiation of bone marrow-derived mesenchymal stem cells and protects against osteoarthritis by suppressing NLRP-3 expression by Nan Min, Jie Ma, Lei Shi, Lin Wang, Chi Liu, Yaonan Zhang, Qingyun Xue

“…Introduction The present investigation evaluates the role of miR-223 mimic in the treatment of osteoarthritis (OA) and postulates the possible molecular mechanism of its action. Material and methods Bone marrow-derived mesenchymal stem cells (BMSCs) were isolated from rats and cultured in chondrogenic medium to stimulate the differentiation of chondrocytes. …”
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A Case of Status Epilepticus in a Patient Experiencing an Acute Attack of Hereditary Angioedema by Danielle Weinberg, Steven Gayda, Kyle Hultz, Hanan Atia, Brian Kohen, Eric Boccio

“…The treatment of an acute attack of HAE should focus on replacing C1-INH and preventing the formation and limiting the action of bradykinin.…”
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Acylated Ghrelin Renders Chemosensitive Ovarian Cancer Cells Resistant to Cisplatin Chemotherapy via Activation of the PI3K/Akt/mTOR Survival Pathway by Attalla Farag El-kott, Ali A. Shati, Mohammed Ali Al-kahtani, Sultan Alqahtani

“…This study investigated the effect of acylated synthetic ghrelin (AG) on the survival and proliferation of human chemosensitive ovarian cancer cells (A2780) and explored some mechanisms of action with a focus on the p53 apoptotic pathway and PI3K/Akt and NF-κB survival pathways. …”
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Mesenchymal stem cells and their extracellular vesicle therapy for neurological disorders: traumatic brain injury and beyond by Aref Yarahmadi, Masoumeh Dorri Giv, Reza Hosseininejad, Azin Rezaie, Narges Mohammadi, Hamed Afkhami, Hamed Afkhami, Hamed Afkhami, Arastoo Farokhi

“…This review explores the progress and prospects of MSC therapy in TBI, focusing on mechanisms of action, therapeutic benefits, and the challenges and potential limitations of using MSCs in treating neurological disorders.…”
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Requirements for Police Officer’s Personality in Terms of Globalization and the Implementation of International Standards of Law Enforcement Officers’ Conduct by D. V. Shvets, N. O. Rastorguyeva

“…The following requirements to the police officer’s personality have been singled out on the basis of international documents: ability to be at the same time the representative of a society, the state and the law; respect for the law, honesty, professionalism; intolerance to any action that constitutes torture or other cruel, inhuman or degrading treatment or punishment, intolerance to corruption; intolerance to racism and xenophobia; ability to show prudence, tolerance, maturity, sense of justice and communication skills, and if necessary – leadership and organizational qualities; indifference to politics that ensures objectivity of policing and equal treatment of citizens; high professionalism, honesty, impartiality and efficiency, taking into account only the public interests and the interests of the people they serve to, etc. …”
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Changes in household food security, access to health services and income in northern Lao PDR during the COVID-19 pandemic: a cross-sectional survey by Jennifer R Head, Phetsavanh Chanthavilay, Helen Catton, Ammaline Vongsitthi, Kelley Khamphouxay, Niphone Simphaly

“…The households who experienced no change in meeting food needs produced a greater percentage of their food from homegrown methods (4.22% more, 95% CI 1.28 to 7.15), than households who found it more difficult.Conclusions Pandemic-associated shocks may have large effects on food insecurity. Action is needed to mitigate consequences of the pandemic on nutrition. …”
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Characteristics and publication status of minimally invasive glaucoma surgery trials registered in ClinicalTrials.gov, 2007–2024: a cross-sectional study by Chuzhi Peng, Hongyan Jia, Jianping Hu, Yonghong Jiao

“…Based on the anatomical site of action and the research content, MIGS trials were classified into different groups, and intergroup comparisons were conducted. …”
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Walker 256 Tumor Growth Suppression by Crotoxin Involves Formyl Peptide Receptors and Lipoxin A4 by Patrícia Brigatte, Odair Jorge Faiad, Roberta Cornélio Ferreira Nocelli, Richardt G. Landgraf, Mario Sergio Palma, Yara Cury, Rui Curi, Sandra Coccuzzo Sampaio

“…The blockage of these receptors also abolished the inhibitory action of CTX on tumor growth and blood vessel formation and the decrease in blood vessel diameter. …”
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Mixed vulnerabilities: the biological risk of high parity is aggravated by emergency referral in Benin, Malawi, Tanzania and Uganda by Manuela Straneo, Lenka Beňová, Thomas van den Akker, Muzdalifat S. Abeid, Elizabeth Ayebare, Jean-Paul Dossou, Greta Handing, Bianca Kandeya, Andrea B. Pembe, Claudia Hanson

“…We used e-registry data collected in 16 hospitals included in the Action Leveraging Evidence to Reduce perinatal morbidity and morTality (ALERT) trial. …”
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Effective interventions to prevent youth vaping behaviours: a rapid review by Ana Paula Belon, Laura Nieuwendyk, Tasha Allen, Melissa Worrell, Candace I J Nykiforuk

“…Equity-related findings suggested that younger youth may be less responsive to the interventions. Recommendations for action are provided.Conclusions We suggest that combining multiple interventions targeting different levels of intrusiveness and outcomes may be more effective in preventing youth vaping behaviours. …”
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