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8001
Health promoting palliative care interventions in African low-income countries: a scoping review
Published 2024-04-01“…Interventions sought to strengthen community action by reinforcing the skills and knowledge of community health workers (usually unpaid volunteers). …”
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8002
Unaccountable counting: the folly of incorporating open ocean carbon sinks in Nationally Determined Contributions
Published 2024-08-01“…The national climate action plans to cut greenhouse gas emissions, referred to as Nationally Determined Contributions (NDCs), currently include anthropogenic land-based carbon fluxes but typically exclude open ocean carbon sinks within Exclusive Economic Zones (EEZs). …”
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8003
Antibacterial and antibiofilm activity of peptide PvGBP2 against pathogenic bacteria that contaminate Auricularia auricular culture bags
Published 2022-11-01“…An in silico predicted antimicrobial peptide from the β-1,3-glucan-binding protein sequence of Penaeus vannamei, designated PvGBP2 (FLKLGRKSRYGMLKL), was screened and its antibacterial effect and mechanism of action on the isolated Bacillus spp. explored. The minimal inhibitory concentrations (MIC) of PvGBP2 on Bacillus spp. were 15.6–31.25 μg/mL. …”
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8004
MIMO Control Architectures for Secondary Voltage Regulation in Electrically Coupled Transmission Grids: Design and Dynamic Performance
Published 2025-01-01“…Specifically, the Decoupling control method and the Linear Quadratic Regulator with Integral action control method are applied to the secondary voltage regulation of the Italian transmission system. …”
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8005
Does heatwaves/above-average temperature increase interpersonal violent behavior? A scoping review
Published 2024-12-01“…., promoting green spaces and reducing pollution) and at the level of individual city institutions, which can monitor the phenomenon and take action, such as increasing the presence of security personnel in anticipation of periods of highest temperatures.…”
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8006
Heterologous expression of SpsTAC2 in Arabidopsis affected branch angle and secondary vascular system development
Published 2025-12-01“…This study can help to characterize the regulatory effect of the TAC gene on the branching angle and explore its effect on the branching angle and vascular system development, and also help to explore the possible molecular regulatory mechanism, which can provide a theoretical basis for further elucidation of the mechanism of action of the IGT gene family.…”
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8007
Effects of GS-CA1 on nuclear envelope-associated early HIV-1 infection steps
Published 2025-02-01“…However, their multiple mechanisms of action have not been fully characterized. Here, we investigated the effects of GS-CA1 on the early stages of HIV-1 infection, specifically the steps involving the nuclear envelope, in comparison to the antiviral cytokine IFN-β. …”
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8008
Spinal Cord Stimulation for Refractory Angina Pectoris: Current Status and Future Perspectives, a Narrative Review
Published 2025-01-01“…A systematic literature review was conducted to evaluate the clinical effectiveness, mechanisms of action, and safety profile of SCS in treating RAP. …”
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8009
Practical Aspects of Clinical Manifestations, Pathogenesis and Therapy of Alcoholic Liver Disease and Non-alcoholic Fatty Liver Disease: Expert Opinion
Published 2023-11-01“…In the treatment of NAFLD, diet and lifestyle modification, weight loss, the use of insulin sensitizers, vitamin E, statins (in the presence of hyperlipidemia) and drugs with metabolic activity are effective.Currently, a point of view is being actively expressed about the synergism of the action of alcohol and the metabolic syndrome on the development of fibrosis, cirrhosis, and hepatocellular carcinoma. …”
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8010
Changes in the Fluorescence Tracking of NaV1.6 Protein Expression in a BTBR T+Itpr3tf/J Autistic Mouse Model
Published 2019-01-01“…The axon initial segment (AIS), the site of action potential initiation in neurons, is a critical determinant of neuronal excitability. …”
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8011
How integrated knowledge translation worked to reduce federal policy barriers to the implementation of medication abortion in Canada: a realist evaluation
Published 2025-02-01“…We found key components of the causal explanatory configurations included: researcher motivation to move evidence into action, trusted reputations as credible sources of evidence, strategic partnerships, understanding of health policy processes, and researcher roles as a trusted convenor between key groups and decision makers. …”
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8012
Contribution of Arginine Catabolic Mobile Element and Copper and Mercury Resistance Element in Methicillin-Resistant Staphylococcus aureus: A Vantage Point
Published 2022-01-01“…This review highlights the comprehensive view on ACME and COMER structure, their distribution, and the mechanism of action along with pathogenetic features of USA3000 encompassing their role in biofilm formation, adhesion, quorum sensing, resistance to antibiotics, chemotaxis, and nutrient uptake. …”
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8013
The Bipolar Depression Electrical Treatment Trial (BETTER): Design, Rationale, and Objectives of a Randomized, Sham-Controlled Trial and Data from the Pilot Study Phase
Published 2015-01-01“…The evaluation of biological markers will also help in understanding the pathophysiology of BD and the mechanisms of action of tDCS.…”
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8014
Telephone coaching supports exercise in people with prediabetes and diabetes: A mixed-methods study
Published 2025-01-01“…Methods: The telefone coaching intervention included problem-solving strategies to address barriers to successfully implementing an action plan to achieve exercise goals. Data were collected from January to December 2020 in Juiz de Fora, Minas Gerais, Brazil. …”
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8015
Chromogranin A: From Laboratory to Clinical Aspects of Patients with Neuroendocrine Tumors
Published 2018-01-01“…Even if the growth of the neoplasm was significantly inhibited, it is still unclear whether its antiproliferative action is greater than that of octreotide and lanreotide. …”
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8016
Role of CXCL10 released from osteocytes in response to TNF-α stimulation on osteoclasts
Published 2025-01-01“…However, its mechanism of action in osteocytes remains unclear. In this study, highly purified osteocytes were isolated from dentin matrix protein 1 (DMP1)-Topaz mice using cell sorter. …”
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8017
Psoralidin: emerging biological activities of therapeutic benefits and its potential utility in cervical cancer
Published 2024-09-01“…Therefore, further investigation is needed in area of drug delivery and mechanism of action to fully harness the beneficial effects of psoralidin. …”
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8018
An Investigation of the Anticancer Mechanism of <i>Caesalpinia sappan</i> L. Extract Against Colorectal Cancer by Integrating a Network Pharmacological Analysis and Experimental Va...
Published 2025-01-01“…(CSE) against CRC cells, focusing on the identification of bioactive compounds and their mechanisms of action. A network pharmacology analysis was conducted to identify potential CRC targets and bioactive compounds of CSE, using LC-MS for compound identification. …”
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8019
Successful open defecation-free intervention in low- and middle-income countries: a qualitative synthesis systematic review protocol
Published 2025-01-01“…Furthermore, this review seeks to identify gaps in the available literature and areas that require additional investigation and action.Methods and analysis Inclusion criteria were developed considering issues related to open defecation in LMICs, sanitation interventions and behavioural change. …”
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8020
Perspective: Current Scientific Evidence and Research Strategies in the Role of Almonds in Cardiometabolic Health
Published 2025-01-01“…A number of research gaps on almond consumption and cardiometabolic health were identified that should be addressed to further understand their role in the various cardiometabolic endpoints, including the mechanisms of action interactions with the microbiome with regular consumption and their role as part of a healthy dietary pattern for both individuals and the general population.…”
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