Intelligent Multi-Agent Based Multilayered Control System for Opportunistic Load Scheduling in Smart Buildings by Muhammad Babar Rasheed, Nadeem Javaid, Muhammad Sheraz Arshad Malik, Muhammad Asif, Muhammad Kashif Hanif, Muhammad Hasanain Chaudary

“…., price agent <inline-formula> <tex-math notation="LaTeX">$p_{a}$ </tex-math></inline-formula>, sensor agent <inline-formula> <tex-math notation="LaTeX">$s_{a}$ </tex-math></inline-formula>, decision agent <inline-formula> <tex-math notation="LaTeX">$d_{a}$ </tex-math></inline-formula>, load agent <inline-formula> <tex-math notation="LaTeX">$l_{a}$ </tex-math></inline-formula>, and action agent <inline-formula> <tex-math notation="LaTeX">$a_{a}$ </tex-math></inline-formula>, are developed to control residential loads, such as normal load (<italic>nl</italic>) and heavy load (<italic>hl</italic>). …”
Get full text

Actively protective combinatorial analysis: A scalable novel method for detecting variants that contribute to reduced disease prevalence in high-risk individuals by J Sardell, S Das, K Taylor, C Stubberfield, A Malinowski, M Strivens, S Gardner

“…The results support the mechanism of action hypotheses identified in our original causative disease analyses. …”
Get full text

The Protective Effects of 18β-Glycyrrhetinic Acid on Imiquimod-Induced Psoriasis in Mice via Suppression of mTOR/STAT3 Signaling by Haiming Chen, Huazhen Liu, Bin Tang, Yuchao Chen, Ling Han, Jingjie Yu, Yuhong Yan, Chuanjian Lu

“…In this study, we evaluated the protective effect of GA on psoriasis and its mechanisms of action in imiquimod-induced psoriasis-like mouse model. …”
Get full text

Qingfei Tongluo Mixture Attenuates Bleomycin-Induced Pulmonary Inflammation and Fibrosis through mTOR-Dependent Autophagy in Rats by Shuyu Ge, Zhenghong Guo, Ting Xiao, Pingping Sun, Bo Yang, Yin Ying

“…This study aims to confirm whether it has a therapeutic effect on bleomycin-induced IPF in rats and to elucidate its mechanism of action. Male SD rats were randomly divided into the following groups: control, model, CQ + QFTL (84 mg/kg chloroquine (CQ) + 3.64 g/kg QFTL), QFTL-L, M, H (3.64, 7.28, and 14.56 g/kg, respectively) and pirfenidone (PFD 420 mg/kg). …”
Get full text

Microbial proliferation deteriorates the corrosion inhibition capability, lubricity, and stability of cutting fluid by Yuanyuan Shen, Wenkai Zhang, Lili Wu, Yaohua Dong, Guoqiang Guo, Lihua Dong, Zhangwei Guo

“…The rolling and bridging action of the resulting fungal mycelium caused flocculation of the effective components in the cutting fluid, resulting in reduced lubricity and poor stability. …”
Get full text

Application of antisense oligonucleotide drugs in amyotrophic lateral sclerosis and Huntington’s disease by Kaili Ou, Qingqing Jia, Dandan Li, Shihua Li, Xiao-Jiang Li, Peng Yin

“…This review provides a comprehensive overview of the development, mechanisms of action, limitations, and clinical applications of ASO drugs in neurodegenerative diseases, with a specific focus on ALS and HD therapeutic strategies.…”
Get full text

Autologous Microfragmented Adipose Tissue Reduces the Catabolic and Fibrosis Response in an In Vitro Model of Tendon Cell Inflammation by Marco Viganò, Gaia Lugano, Carlotta Perucca Orfei, Alessandra Menon, Enrico Ragni, Alessandra Colombini, Paola De Luca, Pietro Randelli, Laura de Girolamo

“…In this in vitro model of tendon cell inflammation, the paracrine action of μFAT, exerted by anti-inflammatory molecules and growth factors, was able to inhibit the expression of fibrosis and catabolic markers. …”
Get full text

Effectiveness of a Short-Term Treatment of Oxygen-Ozone Therapy into Healing in a Posttraumatic Wound by Irene Degli Agosti, Elena Ginelli, Bruno Mazzacane, Gabriella Peroni, Sandra Bianco, Fabio Guerriero, Giovanni Ricevuti, Simone Perna, Mariangela Rondanelli

“…Compared to standard dressing and other treatments reported in the literature it showed a shorter time of action.…”
Get full text

Seasonal Profile and Five-Year Trend Analysis of Malaria Prevalence in Maygaba Health Center, Welkait District, Northwest Ethiopia by Fitsum Tigu, Tsegay Gebremaryam, Asnake Desalegn

“…The severe species of P. falciparum was found to be the dominant parasite reported in the study area. A collaborative action between the national malaria control program and its partners towards the transmission, prevention, and control of the two deadly species is highly recommended.…”
Get full text

HDAC1-3 inhibition triggers NEDD4-mediated CCR2 downregulation and attenuates immunosuppression in myeloid-derived suppressor cells by Zhiqi Xie, Jinjin Shao, Zeren Shen, Zhichao Ye, Yoshiaki Okada, Daisuke Okuzaki, Naoki Okada, Masashi Tachibana

“…Our findings reveal a novel mechanism of action of HDAC1-3 inhibitors in MDSCs and suggest a potential synergistic immunotherapy strategy for clinical benefit in HCC.…”
Get full text

Efficient hydrogen peroxide reduction in glutathione peroxidase cycle using cost-effective FeSe2 nanospheres by Saif Khan, Sundeep S. Bhagwath, Mohammad Rehan Ajmal, Intikhab A. Ansari, Mohtashim Lohani, Sanjaya Pavgada Raghunandana, Mohammad Luqman

“…These nanospheres (termed Nanozymes) mimic the enzymatic action of natural antioxidants, such as the glutathione peroxidase (GPx) enzyme, in biological systems. …”
Get full text

Visit of the Soviet Union journalists' delegation to Finland and the Baltic countries in 1937: the report of the leader of the delegation, Boris Michailov, to Stalin and Molotov by Zenonas Butkus, Magnus llmjärv

“…The visit itself was not just an ordinary fact of cultural ties but an action motivated by international political considerations, which has not been addressed in historical works yet. …”
Get full text

Current Perspectives on Treatment of Gram-Positive Infections in India: What Is the Way Forward? by Atul P. Kulkarni, Vasant C. Nagvekar, Balaji Veeraraghavan, Anup R. Warrier, Deepak TS, Jaishid Ahdal, Rishi Jain

“…The most important step is development of newer antimicrobial agents with novel mechanisms of action and favourable pharmacokinetic profile. This review provides a synopsis about the current burden, treatment options, and the challenges faced by the clinicians in the management of GPIs such as MRSA, Quinolone-resistant Staphylococcus, VRE, and drug-resistant pneumococcus in India.…”
Get full text

Building a practice-based research network for healthcare integration: a protocol paper for a mixed-method project by Danielle Mazza, Sanne Peters, Grant Russell, Christopher Barton, Elizabeth Ann Sturgiss, Samantha Paubrey Chakraborty, Timothy Staunton-Smith, Maria De Leon - Santiago

“…Our iterative approach will be informed by a programme logic model and consists of: preparation work (pre-implementation assessment, literature review, community and stakeholder engagement), adaptation and building for a sustainable collaboration (strategy for recruitment and sustainment of members) and planning for network action (designing and implementing priority initiatives, monitoring and follow-up).Ethics and dissemination This project was approved by the Monash Health ethics committee (ERM Reference Number: 76281; Monash Health Ref: RES-21-0000-392L) and the Monash University Human Research ethics committee (Reference Number: 29786). …”
Get full text

Docosahexaenoic acid-rich fish oil prevented insulin resistance by modulating gut microbiome and promoting colonic peptide YY expression in diet-induced obesity mice by Wanxiu Cao, Fang Liu, Robert W. Li, Yaoxian Chin, Yuming Wang, Changhu Xue, Qingjuan Tang

“…Herein, DHA-FO enhanced insulin action on glucose metabolism by altering gut microbiome and facilitating colonic PYY expression in DIO mice.…”
Get full text

Research progress and application prospects of flexible wearable sensor in spacesuit by Aiming Bu, Wanxin Zhang, Qian Ran, Dongyue Liu, Jialu Ma, Rongqing Wang, Kun Shang, Hongrui Yang, Zhiqiang Mei

“…It can realize the benefits of heart rate, breathing, sweat, action recognition and date acquisition, etc. The joint resistance characteristics of spacesuit is revealed under pressure were studied by wearing flexible wearable sensors, which provides a theoretical basis for improving the performance of spacesuit. …”
Get full text

Biodiversity reporting: Comparing listed entities in the United Kingdom and South Africa by Dino Da Mata, Timothy Lai, Dusan Ecim, Warren Maroun, Dannielle Cerbone

“…Practical implications: The disclosure schematic serves as a valuable tool for evaluating biodiversity reporting in different national contexts and provides a framework for companies developing biodiversity action plans. The findings help stakeholders assess organisations’ progress in achieving biodiversity objectives and integrating biodiversity considerations into business operations. …”
Get full text

Community advisory boards as implementation strategies to center partner and patient voice in community health centers by Rebekka M. Lee, Kamini Mallick, James G. Daly, Vetta Sanders Thompson, Elise Hoffman, Maria Papadopoulos, Stacey Curry

“…Conclusion: In alignment with the Translational Science Benefits Model, this study expands research impact through comprehensive mixed methods measurement of community engagement and by transforming findings into an action-orientated guide for CHCs to implement CABs to guide evidence-based decision-making for community and public health impact. …”
Get full text

Versatile High-Throughput Platform for Focused Ultrasound In Vitro Application by Steffen H. Tretbar, Marc Fournelle, Christian Degel, Franz-Josef Becker, Peter Weber, Sarah Therre-Mohr, Wolfgang Bost, Lisa Landgraf, Andreas Melzer

“…For the more efficient application of ultrasound in future therapies, fundamental research is needed on the mode of action of ultrasound on biological systems using therapeutic frequencies. …”
Get full text

The mental health impact of COVID-19: the need for community interventions and collaboration for recovery by Nadarajah Rajeshkannan, Daya Somasundaram, Balachandran Kumarendran, Thirunavukarasu Kumanan, Ivan Dinesh Aloysius, Nalayini Sugirthan, Sivanantham Sasikumar, Nalayini Jegathesan

“…Materials and methods: This qualitative study aims to map out the mental health consequences of the COVID-19 pandemic and suggest recovery strategies based on analyzing COVID-19 mental health and psychosocial impact-related comments on social/news media, participant’s observations, and participant action research. The results and suggested recovery strategies were triangulated with literature survey. …”
Get full text