Spatiotemporal simulation of blue-green space pattern evolution and carbon storage under different SSP-RCP scenarios in Wuhan by Guiyuan Li, Wangzhen Wang, Bowen Li, Zhongyuan Duan, Liang Hu, Jingwen Liu

“…As a result, immediate action is required to undertake climate mitigation and adaptation strategies. …”
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Assessment of Health Risks in Wheat Crop Irrigated by Manka Canal, Dera Ghazi Khan, Pakistan by Muhammad Anwar ul Hassan, Sabiha Javied, Umair Riaz, Muneera A. Saleh, Khalid H. Alamer, Naila Siddique, Ambreen Aslam, Nabeela Noor, Qamar uz Zaman

“…Untreated water from the canal is used by farmers for local crop irrigation. Immediate action is crucial to assess heavy metal levels and ensure soil suitability for agriculture as metal pollution persists. …”
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Monoclonal anti-CD38 therapy in human myeloma: retrospects and prospects by Alberto L. Horenstein, Angelo C. Faini, Angelo C. Faini, Fabio Morandi, Erika Ortolan, Paola Storti, Nicola Giuliani, Nicola Giuliani, Paul G. Richardson, Fabio Malavasi, Fabio Malavasi

“…This review, a collaborative effort between basic scientists and clinical experts, explores some of the lesser-known mechanisms of antibody action and interactions with CD38 at key stages of treatment. …”
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A literature review of recent advances in gastric cancer treatment: exploring the cross-talk between targeted therapies by Reza Panahizadeh, Padideh Panahi, Vahid Asghariazar, Shima Makaremi, Ghasem Noorkhajavi, Elham Safarzadeh

“…The selection criteria included peer-reviewed articles published primarily within the last 10 years, with a focus on studies that provided insights into targeted therapies and their mechanisms of action, clinical efficacy, and safety profiles. The findings indicate that these immunotherapy strategies can enhance treatment outcomes for GC, aligning with current treatment guidelines. …”
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Contrast Medium Use in Computed Tomography for Patients Presenting with Headache: 4-year Retrospective Two-Center Study in Central and Western Regions of Ghana by Bashiru Babatunde Jimah, Benjamin Dabo Sarkodie, Asare Kwaku Offei, Ewurama Andam Idun, Dorothea Anim, Edmund Brakohiapa, Benard Ohene Botwe

“…Further studies to improve the knowledge of agents, mechanism of action, and safety of contrast media used among practitioners in Ghana is recommended.…”
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Approbation of the mechanism of economic reliability on the example of an industrial enterprise by A. R. Terentyeva

“…The author of the article came to the following conclusions: the implemented mechanism of economic reliability in the activity of an industrial enterprise allows identifying bottlenecks, as well as developing measures to eliminate them, thereby increasing the level of economic reliability; the action of this mechanism should be continuous, since the intensification of technological dynamics is an aggressive factor influencing the efficiency, stability and sustainability of the functioning of an industrial enterprise. …”
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Let us be heard: critical analysis and debate of collaborative research approaches used in implementation science research with equity-deserving populations by Sarah Madeline Gallant, Cynthia Mann, Britney Benoit, Megan Aston, Janet Curran, Christine Cassidy

“…Discussion IKT and Community Based Participatory Action Research (CBPR) were deemed the most aligned approaches within the case, and boast many similarities; however, they are fundamentally distinct. …”
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Maintenance of Self-Renewal and Pluripotency in J1 Mouse Embryonic Stem Cells through Regulating Transcription Factor and MicroRNA Expression Induced by PD0325901 by Zhiying Ai, Jingjing Shao, Xinglong Shi, Mengying Yu, Yongyan Wu, Juan Du, Yong Zhang, Zekun Guo

“…Thus, to seek for the crucial miRNA and key regulatory genes that establish ESC properties in MEK/ERK pathway, we performed microarray analysis and small RNA deep-sequencing of J1 mESCs treated with or without PD0325901 (PD), a well-known inhibitor of MEK/ERK signal pathway, followed by verification of western blot analysis and quantitative real-time PCR verification; we found that PD regulated the transcript expressions related to self-renewal and differentiation and antagonized the action of retinoic acid- (RA-) induced differentiation. …”
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Magnetic Vestibular Stimulation (MVS). A research tool with possible implementation in rehabilitation of stroke-affected athletes – a review by Monika Olszanecka, Tomasz Olszanecki, Anna Hanslik, Agata Białek, Agnieszka Walczak, Magdalena Mendak

“… Background: People often experience vertigo and other co-occurring effects caused by the action of a strong magnetic field, such as those found in the MRI generator. …”
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Crop water productivity assessment and planting structure optimization in typical arid irrigation district using dynamic Bayesian network by Yantao Ma, Jie Xue, Xinlong Feng, Jianping Zhao, Junhu Tang, Huaiwei Sun, Jingjing Chang, Longke Yan

“…Maximizing crop water productivity while ensuring food security has led to increased acreage for cotton, Chinese dates and walnuts. Under the combined action of the five optimization objectives, the average increase of crop water productivity is 14.97%, and the average increase of ecological benefit is 3.61%, which is much higher than the growth rate of irrigation water consumption of cultivated land. …”
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Resistance to viruses of potato: current status and prospects by S. S. Makarova, V. V. Makarov, M. E. Taliansky, N. O. Kalinina

“…The most promising approaches are (1) site-directed mutagenesis of the genes conferring specific resistance to make their action much broader and (2) the use of non-specific (nonhost) resistance to generate plants resistant to unrelated viruses and, in some cases, to other pathogens and even abiotic stresses. …”
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Chrysoeriol ameliorates hyperglycemia by regulating the carbohydrate metabolic enzymes in streptozotocin-induced diabetic rats by Baskaran Krishnan, Abirami Ramu Ganesan, Ravindran Balasubramani, Dinh Duc Nguyen, Soon Woong Chang, Shaoyun Wang, Jianbo Xiao, Balamuralikrishnan Balasubramanian

“…There was a diminish action found in liver glycogen synthase of tested rat with a rise in gamma-glutamyl transpeptidase, towards normal levels upon treatment with chrysoeriol. …”
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Diagnosis of land degradation and analysis of its spatiotemporal evolution in the Jinghe River Basin, Xinjiang by Ya Peng, Zhaopeng Wu, Xinpeng Shi, Yuting Tian, Ruirui Zhang

“…Land degradation in Jinghe County is formed by the combined action of nature and human social activities. Human activities are the leading factor in the increase of LDI, but natural factors have a significant correlation with local LDI changes; temperature, Normalized Difference Vegetation Index (NDVI), and population have a higher impact on the LDI changes in Jinghe County, and local LDI changes respond more strongly to precipitation, evapotranspiration, and Gross Domestic Product (GDP). …”
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Selective Immunomodulation of Inflammatory Pathways in Keratinocytes by the Janus Kinase (JAK) Inhibitor Tofacitinib: Implications for the Employment of JAK-Targeting Drugs in Psor... by Martina Morelli, Claudia Scarponi, Laura Mercurio, Francesco Facchiano, Sabatino Pallotta, Stefania Madonna, Giampiero Girolomoni, Cristina Albanesi

“…We demonstrated the selectivity of tofacitinib inhibitory action on IFN-γ and IL-22, but not on TNF-γ or IL-17 proinflammatory signaling, with suppressed expression of IFN-γ-dependent inflammatory genes, and restoration of normal proliferative and differentiative programs altered by IL-22 in psoriatic keratinocyte cultures. …”
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Identification of Cognitive Training for Individuals with Parkinson’s Disease: A Systematic Review by Marina Francesca Gattoni, Silvia Gobbo, Sarah Feroldi, Anna Salvatore, Jorge Navarro, Sandro Sorbi, Francesca Lea Saibene

“…The considered studies applied various experimental interventions for the training of cognitive functions in PwPD: computer-based platforms, exergames, paper-and-pencil programmes, dual-task or treadmill training with action observation therapy, motor imagery, and virtual reality components, interventions targeting precise cognitive domain, tele-rehabilitation, transcranial direct current stimulation, structured cognitive training, and multimodal treatments. …”
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YAT2150 is irresistible in Plasmodium falciparum and active against Plasmodium vivax and Leishmania clinical isolates by Inés Bouzón-Arnáiz, Mukul Rawat, Rachael Coyle, Lionel Brice Feufack-Donfack, Malen Ea, Agnes Orban, Jean Popovici, Lucía Román-Álamo, Antonino Nicolò Fallica, Bárbara Domínguez-Asenjo, Javier Moreno, Elsa M. Arce, Ana Mallo-Abreu, Diego Muñoz-Torrero, Marcus C. S. Lee, Xavier Fernàndez-Busquets

“…Abstract We recently characterized the potent antiplasmodial activity of the aggregated protein dye YAT2150, whose presumed mode of action is the inhibition of protein aggregation in the malaria parasite. …”
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Adsorption of Safranin‐O Dye Onto Almond Shell Sustainable Activated Carbon: Identifying Key Process Factors and Their Effects by Nawras J. Jassim, Fitna H. Younis, Maher T. Alshamkhani

“…ABSTRACT Water pollution is a critical issue requiring urgent action to minimize contamination and ensure a sustainable future for humanity. …”
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Novel soybean peptide iglycin ameliorates insulin resistance of high-fat diet fed C57BL/6J mice and differentiated 3T3L1 adipocytes with improvement of insulin signaling and mitoch... by Yinghuan Wu, Ran Zhao, Minxia Li, Huiyun Li, Zhengwang Chen, Yanying Zhao

“…Thus, more studies are required to identify these bioactive peptides, and elucidate their biological mechanisms of action. In the present study, a novel peptide iglycin was purified from soybean seeds with a molecular mass of 3.88 kDa. …”
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Exosomes of Antler Mesenchymal Stem Cells Improve Postoperative Cognitive Dysfunction in Cardiopulmonary Bypass Rats through Inhibiting the TLR2/TLR4 Signaling Pathway by Chun Yang, Shengnan Sun, Qi Zhang, Jia Guo, Tengfei Wu, Ying Liu, Min Yang, Yan Zhang, Yinghua Peng

“…Mesenchymal stem cells (MSCs) are multipotent cells that have therapeutic potentials mainly through paracrine action via secreting growth factors and cytokines. …”
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Programming Regulation and Strategic Planning in the Health Care Sector by G. V. Muliar

“…These are disadvantages of both the general system of organization and effectiveness of the programs, as well as of certain mechanisms of the implementation, in particular financing of programs on a residual principle (underfunding, and sometimes even its absence); unclear formulation of the purpose and objectives of the programs, which indicate the process rather than the final result; the absence of clearly identified performers and obligated entities; insufficient analytical activity; lack of responsibility for non-compliance with mandatory measures and action plan; insufficient control over funds spending; declarative nature, etc.…”
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