Multi-Physical Intelligent Analysis of the Thermal-Structural-Optical Coupling for Mirror Based on Surrogate Model by Wenxiong Li, Junli Shen, Zhenyu Lu, Shudong Men, Qingwen Wu

“…Therefore, a surrogate modeling approach based on a neural network for the TSO-MCA of mirrors has been proposed to analyze the surface shape of optical system mirrors under the action of multi-physical fields. Firstly, a thermal-structural-optical multi-physical integrated chain(TSO-IC) is established by integrating various disciplinary simulation and analysis tools, through which computational data necessary for the surrogate model are acquired. …”
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Fragile Histidine Triad (FHIT) Suppresses Proliferation and Promotes Apoptosis in Cholangiocarcinoma Cells by Blocking PI3K-Akt Pathway by Qiang Huang, Zhen Liu, Fang Xie, Chenhai Liu, Feng Shao, Cheng-lin Zhu, Sanyuan Hu

“…However, its exact mechanism of action is poorly understood. Phosphatidylinositol 3-OH kinase (PI3K)-Akt-survivin is an important signaling pathway that was regulated by FHIT in lung cancer cells. …”
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Genistein Protects against Spinal Cord Injury in Mice by Inhibiting Neuroinflammation via TLR4-Mediated Microglial Polarization by Xin-Wu Li, Peng Wu, Jian Yao, Kai Zhang, Gen-Yang Jin

“…Our findings suggested that genistein exerted neuroprotective action by inhibiting neuroinflammation by promoting the activation of M2 macrophages, and its underlying mechanisms might be related to the inhibition of the TLR4-mediated MyD88-dependent signaling pathway.…”
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A Systematic Review on Serious Games in Attention Rehabilitation and Their Effects by Leila Shahmoradi, Fatemeh Mohammadian, Meysam Rahmani Katigari

“…There were (57%) casual, (23%) action, (10%) simulation, and (10%) multiple genres. …”
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Redox proteomics reveal a role for peroxiredoxinylation in stress protection by Gerhard Seisenbacher, Zrinka Raguz Nakic, Eva Borràs, Eduard Sabidó, Uwe Sauer, Eulalia de Nadal, Francesc Posas

“…Despite the profound structural and functional knowledge of peroxiredoxins action, information on how the different functions are concerted is still scarce. …”
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Performance Degradation of Subsea Shield Tunnel Segment Accounting for Concrete Strength Loss and Steel Bar Corrosion by Jiaqi Guo, Weiling Yang, Chong Xu, Bo Peng, Jinhai Lin, Yuan Qian

“…Subsea shield tunnels usually serve in a typical corrosive marine environment. Under the action of chloride penetration and carbonization, tunnel lining segments are often damaged because of concrete strength loss and steel bar corrosion induced concrete cracking during their service life, which seriously degrades the service performance of the tunnels. …”
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No Modulatory Effects when Stimulating the Right Inferior Frontal Gyrus with Continuous 6 Hz tACS and tRNS on Response Inhibition: A Behavioral Study by Hannah Brauer, Navah Ester Kadish, Anya Pedersen, Michael Siniatchkin, Vera Moliadze

“…Response inhibition is the cognitive process required to cancel an intended action. During that process, a “go” reaction is intercepted particularly by the right inferior frontal gyrus (rIFG) and presupplementary motor area (pre-SMA). …”
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Two-photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure by Zaneta D. Musimbi, Arkadi Kundik, Jürgen Krücken, Anja E. Hauser, Sebastian Rausch, Peter H. Seeberger, Raluca Niesner, Ruth Leben, Susanne Hartmann

“…Overall, two-photon NAD(P)H-FLIM proved to be a powerful tool for studying specific metabolic pathways in Ascaris larvae and host macrophages, offering valuable insights into the metabolic mechanisms of drug action on both parasite and host.…”
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Loading and Skeletal Development and Maintenance by P. Bergmann, J. J. Body, S. Boonen, Y. Boutsen, J. P. Devogelaer, S. Goemaere, J. Kaufman, J. Y. Reginster, S. Rozenberg

“…There are few data on a possible additive effect of exercise and drugs in osteoporosis treatment, but disuse could decrease drugs action. Exercise programs proposed for bone health are tedious and compliance is usually low. …”
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Hydrodynamic Response to Current and Wind on a Large Floating Interconnected Structure by Sarat Chandra Mohapatra, Pouria Amouzadrad, Iuri Baldaconi da Silva Bispo, C. Guedes Soares

“…A numerical hydrodynamic model for a moored interconnected floating large structure under the action of regular waves is presented to analyze the effect of current and wind. …”
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Full-Scale Model Experimental Study of the Flexural Behavior of Hollow Slabs Strengthened by UHPC by Jinzhi Zhou, Zihao Wen, Weiqi Mao, Chuheng Zhong, Kangning Wang, Chenxu Zhou

“…The UHPC layer and the prestressed concrete hollow slab were connected by shear studs to produce a good composite action between them, and the bending performance and bearing capacity of the whole structure were clearly improved. …”
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Chronic C-Type Natriuretic Peptide Infusion Attenuates Angiotensin II-Induced Myocardial Superoxide Production and Cardiac Remodeling by Yasuhiro Izumiya, Satoshi Araki, Hiroki Usuku, Taku Rokutanda, Shinsuke Hanatani, Hisao Ogawa

“…This study tested the hypothesis that suppression of superoxide production contributes to the cardioprotective action of CNP. Angiotensin II (Ang II) or saline was continuously infused subcutaneously into mice using an osmotic minipump. …”
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Mycobacterium tuberculosis Protein Rv3841 Activates Dendritic Cells and Contributes to a T Helper 1 Immune Response by Seunga Choi, Han-Gyu Choi, Ki-Won Shin, Yong Woo Back, Hye-Soo Park, Jae Hwi Lee, Hwa-Jung Kim

“…Here, we studied the action of Rv3841 in maturation of dendritic cells (DCs) and its engagement in the development of T-cell immunity. …”
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Natural antifibrosis potential of anthocyanin in Ipomoea batatas against Transforming Growth Factor beta Type II receptor by in silico ADMET and molecular docking study by Evi Lusiana, Ernawati Sinaga, Zen Hafy, Debby Handayati Harahap, Ramzi Amin, Irsan Saleh

“…Anthocyanins derived from I. batatas can suppress the action of Transforming Growth Factor beta Type II Receptor (TGFβRII) to prevent fibrosis progression. …”
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Mapping the extent of unhealthy food advertising around schools in Tāmaki Makaurau/Auckland by Karolina Kneller, Kelly Garton, Daniel J. Exeter, Victoria Egli

“…The score may be used to increase community awareness of the ubiquity of unhealthy advertising in children’s neighbourhoods and advocate for policy change.Practitioner pointsAdvertising present in the vicinity of 62% of Auckland schools; 83% of adverts promoted unhealthy food and/or drinksNovel advertising score assesses the spatial distribution of unhealthy advertising exposure.Advertising exposure score is significantly related to neighbourhood deprivation.Findings show the need for policy action to limit children’s advertising exposure around their schools in NZ.…”
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Effect of γ-ethyl-γ-phenyl-butyrolactone (EFBL), anticonvulsant and hypnotic drug, on mouse brain catecholamine levels by Rasgado Lourdes A. Vega, Villanueva Iván, Díaz Fernando Vega

“…To clarify its mechanism of action, the effects of EFBL, GBL and HEPB on dopamine (DA) and noradrenaline (NA) brain levels were investigated. …”
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The Effects of Destemming/Crushing and Pressing Conditions in Rosé Wine Production by Lorenzo Guerrini, Ferdinando Corti, Giulia Angeloni, Piernicola Masella, Agnese Spadi, Luca Calamai, Alessandro Parenti

“…This could be related to the chemical composition and consistency of the different berry zone, which interact with the mechanical action of the destemmer/crusher and press. Conclusions. …”
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Instrumental aspects of proportionality in civil proceedings by O. H. Bortnik, T. V. Stepanenko

“…The application of proportionality in the version of the test, in which the procedure for solving the case (committing a procedural action) is based on a factual (pragmatic) approach in combination with a procedural institutional approach, allows the application of relatively defined legal norms, in relation to which the rules of deontic logic do not apply.…”
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Understanding the behavioral intention of rural women to engage in green poultry farming: A psychological analysis by Pouria Ataei, Hamed Ghadermarzi, Hamid Karimi, Meysam Menatizadeh, Nasim Izadi

“…The results indicated that perceived benefits, perceived susceptibility, cues to action, and conformity significantly influenced rural women's intention to produce green poultry, collectively explaining 51 % of the variance. …”
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Gravitational odd-parity perturbation of a Horndeski hairy black hole: quasinormal mode and parameter constraint by Zhen-Hao Yang, Yun-He Lei, Xiao-Mei Kuang, Bin Wang

“…While in Horndeski gravity, the isospectrality between the odd and even parity perturbations is broken due to the scalar field, the odd perturbation equation can be simplified into a modified RW equation from the perturbed action. In this paper, we propose a new auxiliary field and tortoise coordinate to refine the modified RW equation in Horndeski gravity, and calculate the QNM frequencies of the odd perturbation of a specific hairy black hole. …”
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