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7641
Experimental and Numerical Evaluation of Shear Strength of Directly and Indirectly Loaded Flanged Recycled Self-Compacted Reinforced Concrete Deep Beams
Published 2020-01-01“…Furthermore, by increasing the a/d ratio, the ultimate load was decreased due to the lower contribution of arch action shear transfer in the beam. A web reinforcement spaced at 100 mm and 50 mm increases the ultimate load by 35% and 48%, respectively. …”
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7642
Eigen Solution of Neural Networks and Its Application in Prediction and Analysis of Controller Parameters of Grinding Robot in Complex Environments
Published 2019-01-01“…The results of theoretical analysis and experimental test show that the output traits have an optional effect with joint action. When the input features functioning in prediction increase, higher predicted accuracy can be obtained. …”
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7643
Simulated Experiment of Water-Sand Inrush across Overlying Strata Fissures Caused by Mining
Published 2020-01-01“…The excavation of physical model can reproduce the whole process of water-sand inrush across overlying strata fissures caused by mining to the life. Under the action of mining and water pressure, after the fourth excavation, the mining-induced vertical fractures of overlying strata pass through the entire bedrock and connect the unconsolidated sand bed, which serves as pathways between the unconsolidated sand bed and working face, triggering water-sand inrush. …”
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7644
Effect of <i>Satureja montana</i> Essential Oil on Model Lipid Membranes
Published 2024-12-01“…Although these properties are recognized as playing a key role in the mechanism of action of this substance, many unresolved issues still exist, and fundamental studies focused on such aspects are scarce. …”
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7645
Trimethylamine-N-Oxide Promotes High-Glucose-Induced Dysfunction and NLRP3 Inflammasome Activation in Retinal Microvascular Endothelial Cells
Published 2023-01-01“…ZO-1 expression decreased remarkably with the combined action of TMAO and a high glucose compared to either treatment alone. …”
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7646
Study on the Vibration Effect of Short Footage Blasting Load on Surrounding Rock-Support Structure of Tunnel
Published 2020-01-01“…Then, taking Cuobuling station of Qingdao Metro as the engineering background, the finite element software is used to simulate the tunnel excavation process under the action of short footage multiple blasting. The vibration damage impact of multiple blasting loads on the surrounding rock-supporting structure is analyzed from the accumulated displacement value and vibration velocity cumulative value of the excavation tunnel. …”
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7647
Impact of Coastal Squeeze Induced by Erosion and Land Reclamation on Salt Marsh Wetlands
Published 2024-12-01“…Coastal erosion further caused a 10.5% decline in vegetation elevation and a 46.7% increase in slope steepness, amplifying vulnerability to wave action. Native species were largely replaced by <i>Spartina alterniflora</i>, reducing ecological diversity. …”
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7648
Spontaneous Overgrowth of Jointing in the Working Chambers of Power Gas-Liquid Thermal Installations – Diffusion Dynamic Processes
Published 2024-08-01“…The process of modification and development of a 3D fractured structure based on the Griffiths load theory for dislocations is described, taking into account the gradual sequential transition from a stable state to a growth stage. As a result of the action of such dynamic loads in a solidstate object, a rapid change in the parameters of microcracking is observed, which can be represented as local micro-explosions, viz. the growth and fusion of natural microcracks into larger ones; the emergence of new microcracks; the disclosure of large microcracks with the formation of defects of the next hierarchical level. …”
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7649
Antiviral activity of natural compounds extracted from Mediterranean medicinal plants against SARS-CoV-2
Published 2024-08-01“…This review highlights studies that have investigated the antiviral activities of spices and Mediterranean herbs, as well as their mechanism of action against SARS-CoV-2. Potential therapeutic target mechanisms addressed in this review comprise both host-directed and virus-directed therapies. …”
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7650
Medicinal Plants as a Drug Alternative Source for the Antigout Therapy in Morocco
Published 2020-01-01“…Then, we have classified the medicines, according to their action mechanisms, and we have cited some species that were reported in Moroccan pharmacopeia as antigout. …”
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7651
A Comprehensive Review on Bio-Based Polybenzoxazines Emphasizing Their Antimicrobial Property
Published 2025-01-01“…The incorporation of functional groups like amines, quaternary ammonium salts, and phenolic moieties disrupts microbial processes, enhancing antimicrobial action. Modifications with metal nanoparticles, organic agents, or natural bio-actives further augment these properties. …”
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7652
Species Composition, Diversity, and Habitat Association of Medium- and Large-Sized Mammals in Chimit-Kolla, Abay Gorge, Ethiopia
Published 2021-01-01“…The study area relatively has considerable numbers of medium- and large-sized mammal species, and urgent conservation action is required to reduce the emerging threats (hunting, charcoal production, agriculture, and investment expansion) and ensure survival of mammal species.…”
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7653
Natural bioactive compounds form herbal medicine in Alzheimer’s disease: from the perspective of GSK-3β
Published 2025-02-01“…We summarize the current understanding of alkaloids, phenols, flavonoids, terpenoids and other natural compounds, highlighting their mechanisms of action and preclinical efficacy.…”
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7654
The mechanisms of efficacy and safety of Ginkgo biloba extract in acute ischemic stroke: a real-world study
Published 2025-02-01“…Conclusions The therapeutic effect of GBE in AIS may, in part, be attributed to its ability to enhance the antiplatelet action of aspirin, particularly in inhibiting AA-induced platelet aggregation. …”
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7655
Mesenchymal stem cells-derived exosomes attenuate mouse non-heart-beating liver transplantation through Mir-17-5p-regulated Kupffer cell pyroptosis
Published 2025-02-01“…We found that miR-17-5p was significantly abundant in MSCs-Exo, targeting and regulating the TXNIP expression. This action inhibited NLRP3-mediated pyroptosis of Kupffer cells through the classical Caspase1-dependent pathway, alleviating DCD liver graft injury. …”
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7656
Synthèse des initiatives de recherche et de conservation des chimpanzés (Pan troglodytes verus) au Sénégal
Published 2014-01-01“…Un résumé plus détaillé de tous ces travaux se trouve dans le plan d’action pour le chimpanzé au Sénégal élaboré par Carter en. 2003. …”
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7657
Taking stock of vaccine hesitancy among migrants: a scoping review protocol
Published 2020-05-01“…Introduction At the 72nd World Health Assembly of May 2019, WHO member states prioritised a global action plan to promote migrant and refugee health. …”
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7658
Interrelationship of the Kinin System, Nitric Oxide and Eicosanoids in the Antigen-Induced Arthritis in Rabbits
Published 1999-01-01“…Our results suggest that pressoric alterations induced by L-NAME could not account for all its anti-inflammatory action in this model of experimental arthritis. Additionally the contribution of the kinin system in AIA was characterized as well as its interaction with eicosanoids and nitric oxide.…”
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7659
[Retracted] CuO-TiO2-Chitosan-Berbamine Nanocomposites Induce Apoptosis through the Mitochondrial Pathway with the Expression of P53, BAX, and BCL-2 in the Human K562 Cancer Cell L...
Published 2022-01-01“…As a result of their cytotoxic action, nanocomposites displayed concentration-dependent cytotoxicity. …”
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7660
Targeted co-delivery nanosystem based on methotrexate, curcumin, and PAMAM dendrimer for improvement of the therapeutic efficacy in cervical cancer
Published 2025-01-01“…Abstract The simultaneous administration of multiple drugs within identical nanocarriers to cancer cells or tissues can result in the effective action of drugs at reduced concentrations. In this investigation, PAMAM dendrimers (G4-PAMAM) were employed to link with methotrexate (MTX) using DCC/NHS chemistry and followed by the entrapment of curcumin (Cur) within it. …”
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