Social support perception in parents of children with type 1 diabetes mellitus by Natalia Macarena Maureira MIranda, Claudia Maribel Muñoz Pavez, Maria Cecilia Toffoletto Toffoletto, Ángel Roco Videla

“…Support must go beyond the family, with important action by health professionals and the entire context in which children are inserted, to contribute to adequate management of the disease.…”
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Dynamics of REL, RELA and IRF1 transcription factor expression in U937 macrophages after dioxin exposure by E. V. Kashina, D. Y. Oshchepkov, E. V. Antontseva, M. Y. Shamanina, D. P. Furman, V. A. Mordvinov

“…Macrophages are key regulators of the innate immune response, as well as one of the first types of cells which respond to chemical stress, so the study of the action of TCDD on these cells is important. Putative DREs were predicted using the SITECON software tool in the regulatory regions of the genes encoding transcription factors REL, RELA and IRF1 expressed in macrophages. …”
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A Benzochalcone Derivative, (E)-1-(2-hydroxy-6-methoxyphenyl)-3-(naphthalen-2-yl)prop-2-en-1-one (DK-512), Inhibits Tumor Invasion through Inhibition of the TNFα-Induced NF-κB/MMP-... by Soon Young Shin, Chang Gun Kim, Seunghyun Ahn, You Jung Jung, Dongsoo Koh, Young Han Lee, Yoongho Lim

“…In this study, we synthesized a novel benzochalcone derivative, (E)-1-(2-hydroxy-6-methoxyphenyl)-3-(naphthalen-2-yl) prop-2-en-1-one (DK-512), and characterized its effects on tumor invasion and its mechanism of action. We found that DK-512 strongly inhibited invasion of metastatic MDA-MB-231 breast cancer cells as revealed by a three-dimensional spheroid culture system. …”
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Development of a theoretical framework based on the MAPR model for stage-based, individualized mobile smoking cessation interventions through systematic literature review and exper... by Shuilian CHU, Hang JING, Lirong LIANG, Jun LI

“…The second layer defines five stages of cessation experienced by smokers: contemplation, preparation, action, maintenance, and relapse. The third layer consists of nine intervention strategies that can induce behavioral change in smoking cessation: empathy, education, training, incentives, environmental restructuring, modeling, reminders, feedback, and resources and tools that can be used interchangeably across the five stages of smoking cessation. …”
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Genetic polymorphism of xenobiotic biotransformation genes, TNF-α and IL-4 in obstructive jaundice by A. A. Natalsky, S. V. Tarasenko, A. A. Nikiforov, O. V. Zaytsev, O. D. Peskov

“…Carriers of A allele of TNF-α gene G-308A have higher risk of obstructive jaundice on a background of gallstone disease, while Т alleles of NAT2 Leu161Leu and IL4 C-589T genes have protective action for posthepatic cholestasis.…”
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Systematic review and meta-analysis of propranolol in the prevention and treatment of post-traumatic stress disorder by Haipeng Li, Zhengrong Zhang, Shaojie Yang, Guoqi Zhu

“…Future researches are needed to further clarify the therapeutic potential, mechanisms of action, and long-term safety of propranolol in PTSD treatment.…”
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The use of phase voltage modules to select the damaged phase in case of single-phase earth faults by V. A. Shabanov, A. V. Sorokin

“…The purpose of the article is to investigate the properties and consider the directions of improvement of damaged phase sensors using phase voltage modules, to determine the areas of their selective action depending on the magnitude of the fault resistance at the point of damage. …”
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Opportunities and Difficulties for Strategic Litigation to Advance Digital Rights in the Internet Audience Economy by Swee Leng Harris

“…Analysis of these strategic litigation opportunities necessarily encompasses the EU’s new regime for mass claims under the Representative Action Directive, and interaction between internet users’ digital rights and consumer protection laws. …”
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Estimation of alfalfa weevil, Hypera postica (Coleoptera: Curculionidae) economic damage based on the larval laboratory feeding rate by Mahsa Ghahramani, Seyed Ali Safavi, Shahzad Iranipour

“…If all larvae survive to pupate (whole lifetime consumption), 2.0-4.5 larvae m-2 are tolerable and need no action. However, if a total mortality of 25, 50, or 75% occurs with a constant rate, tolerable densities will increase to (2.5-5.4), (3.2-7.0), and (4.8-10.6) m-2, respectively. …”
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Crowding distance and IGD-driven grey wolf reinforcement learning approach for multi-objective agile earth observation satellite scheduling by He Wang, Weiquan Huang, Sindri Magnússon, Tony Lindgren, Chen Chen, Junyu Wu, Yanjie Song

“…It integrates Q-learning into an improved multi-objective grey wolf optimization framework, designing state-action combinations that balance exploration and exploitation. …”
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Predicting treatment response to ketamine in treatment-resistant depression using auditory mismatch negativity: Study protocol. by Josh Martin, Fatemeh Gholamali Nezhad, Alice Rueda, Gyu Hee Lee, Colleen E Charlton, Milad Soltanzadeh, Karim S Ladha, Sridhar Krishnan, Andreea O Diaconescu, Venkat Bhat

“…Although its antidepressant effects are known to be linked to its action as an antagonist of the N-methyl-D-aspartate (NMDA) receptor, the precise mechanisms that determine why some patients respond and others do not are still unclear.…”
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Specific Features of Police Care Regarding the Minors by S. V. Medvedenko, M. V. Zaburannyi

“…The article is focused on the problems of legal regulation of preventive police action – police care. The authors have carried out the analysis of scientific works, the authors of which studied the peculiarities of the procedure of police care in regard to minors. …”
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EDUCATION LIKE BREACH BETWEEN PAST AND FUTURE by V. S. Voznyak, N. V. Lipin

“…The opposition between action and thinking, revealed by Hannah Arendt, cannot be understood as a divorcement of thinking from reality, since another man appears to be the original reality for a person, namely, in thinking a person enters the space of a meeting with another man, put himself into another person’s mind and with this firstly attains his place in the world, becoming himself, acquiring the image of a man. …”
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Assessment of crack growth development in main pipeline on the basis of elastoplastic model by К. А. Vansovich, I. P. Aistov, А. А. Nakhlestkin, D. S. Beseliya

“…A method for predicting the growth of surface cracks in the wall of the main pipeline under action of operational loads is proposed. The elastoplastic model of surface crack growth under biaxial loading is described on the example of steel 20. …”
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Hijacking of the nervous system in cancer: mechanism and therapeutic targets by Yu Zhang, Qili Liao, Xuyang Wen, Jiayan Fan, Tifei Yuan, Xuemei Tong, Renbing Jia, Peiwei Chai, Xianqun Fan

“…First, we elucidated how the nervous system accelerates tumor growth, metastasis, and the tumor microenvironment both directly and indirectly through the action of signaling molecules. Importantly, neural activity is also implicated in modulating the efficacy of therapeutic interventions, including immunotherapy. …”
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Assessment of an Existing RC Building before and after Strengthening Using Nonlinear Static Procedure and Incremental Dynamic Analysis by Amir A. Hedayat, Hakan Yalciner

“…Nonlinear dynamic time history analyses have been performed by using SDOF models of these buildings under action of different scales of 20 ground motion records. …”
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New Prospects of Cytoprotection in the Treatment and Prevention of Gastric and Intestinal Diseases (Resolution of an Expert Council and Literature Review) by A. I. Martynov, A. A. Sheptulin, I. V. Mayev, A. N. Kazyulin, A. Ye. Karateev, A. V. Melekhov, L. K. Pal’gova, K. L. Raikhel’son

“…It was shown that Rebamipide exhibits positive effects on various parts of the protective barrier of the gastrointestinal tract (GIT), primarily due to its stimulating action on the production of prostaglandins playing a key role in maintaining the cytoprotective properties of the gastrointestinal mucosa. …”
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Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy by Joselyn Rojas, Valmore Bermudez, Jim Palmar, María Sofía Martínez, Luis Carlos Olivar, Manuel Nava, Daniel Tomey, Milagros Rojas, Juan Salazar, Carlos Garicano, Manuel Velasco

“…They also include the action of proinflammatory cytokines, the production of reactive oxygen species, DNA fragmentation (typical of necroptosis in type 1 diabetic patients), excessive production of islet amyloid polypeptide with the consequent endoplasmic reticulum stress, disruption in autophagy mechanisms, and protein complex formation, such as the inflammasome, capable of increasing oxidative stress produced by mitochondrial damage. …”
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THE EFFECT OF QUERCETIN ON MORPHOLOGICAL AND BIOCHEMICAL CHANGES IN RAT LIVER UNDER 270TH DAY CENTRAL DEPRIVATION OF LUTEINIZING HORMONE SYNTHESIS by M.V. Rud, V.I. Shepitko, Ye.V. Stetsuk, O.Ye. Akimov

“…The flavonoid quercetin has capillary-stabilizing properties due to its antioxidant and membrane-stabilizing action. The aim of our study was to determine the changes in immunocompetent liver cells, both qualitative and quantitative, caused by inhibition of central testosterone synthesis in male rats due to the introduction of triptorelin acetate on the 270th day, and the potential effect of quercetin on morphology and liver antigen-presenting cells count against the background of previous administration of triptorelin acetate solution. …”
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Padlet: a tool for fostering collaborative learning and feedback literacy in dental education by Avita Rath

“…Thematic analysis revealed the successful application of Nicol and MacFarlane's feedback principles, including clarifying expectations, promoting self-assessment, facilitating teacher–student dialogue, and encouraging reflection and action.ConclusionThe findings of this study suggest that Padlet, with its unique features, offers a valuable tool for educators seeking to foster collaborative learning and feedback literacy in dental education. …”
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