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7501
Role of Barystatic Sea Level Change in Global Mass Conservation and Its Excitation to Length‐Of‐Day Variations
Published 2025-01-01“…Due to slight fluctuations in cryospheric effects and the substantial compensatory action of the barystatic sea level, differences in the land hydrological excitation do not lead to significant deviations in the total LOD mass term between EAM products and GRACE/GFO mass estimates.…”
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7502
Safety and Selection Criteria of Single-joint Hybrid Assistive Limb for Upper Limb Paralysis After Stroke: A Phase I Trial
Published 2025-01-01“…No serious adverse events related to HAL-SJ occurred, and participants demonstrated significant improvements in the Fugl-Meyer Assessment Upper Extremity (FMA-UE) and Action Research Arm Test (ARAT) (pre- vs. post-intervention; p < 0.05). …”
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7503
Factors associated with delayed referrals of patients with sepsis from primary to tertiary healthcare in Blantyre, Malawi: a qualitative study
Published 2025-01-01“…Primary care facilities face several challenges that delay referrals from primary to tertiary health facility of patients with sepsis, such as lack of referral transport, poor communication, poor road network, shortage of skilled healthcare workers, patient preferences, delayed treatment-seeking action, and ambulances prioritising maternal conditions. …”
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7504
Oxidative Stress in Hypertensive Patients Induces an Increased Contractility in Vein Grafts Independent of Endothelial Function
Published 2011-01-01“…Extraendothelial NO counter-regulates contractility in SV. However, this action could be altered in hypertensive situations by an increased oxidative stress or a decreased ability of nNOS to produce NO. …”
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7505
Eski Türklerin Savaş Taktikleri ve Savaş Alanındaki Uygulamaları
Published 2021-12-01“…If the estimations promise for a success, then they would start the action. If not, they used to cancel the assault. Scythians, Huns, Kök Türks and the succeeding Turkic peoples applied this strategy very well.…”
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7506
Changing of expression actinbinding proteins in the kidney under dehydration
Published 2018-04-01“…We explored the osmoregulatory action of prolonged hydration and dehydration on the protein composition of actin cytoskeleton in rats depending on the presence or absence of the actively expressing vasopressin gene in the genome. …”
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7507
Assessment of groundwater intrinsic vulnerability using GIS-based DRASTIC method in district Karak, Khyber Pakhtunkhwa, Pakistan
Published 2025-02-01“…The concentration of Nitrate >10 ppm represent that some human action has contributed toward the highest concentration.…”
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7508
Metabolic Activity in Human Intermuscular Adipose Tissue Directs the Response of Resident PPARγ<sup>+</sup> Macrophages to Fatty Acids
Published 2024-12-01“…Thus, future in-depth studies on IMAT-resident PPARγ<sup>+</sup> macrophage action mechanisms will elucidate the role of skeletal muscle in the pathogenesis of human metabolic dysfunction.…”
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7509
Advancements in Liposomal Nanomedicines: Innovative Formulations, Therapeutic Applications, and Future Directions in Precision Medicine
Published 2025-01-01“…This manuscript provides an in-depth review of recent advancements in liposomal formulations, highlighting their composition, targeted delivery strategies, and mechanisms of action. We explore the evolution of liposomal products currently in clinical trials, emphasizing their potential in addressing diverse medical challenges. …”
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7510
Examining alternative approaches to antibiotic utilisation: A critical evaluation of phage therapy and antimicrobial peptides combination as potential alternatives
Published 2025-03-01“…While the precise mechanisms underlying the synergistic action of AMPs and bacteriophages remain unclear, our findings underscore the need for further research in this promising domain. …”
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7511
Oxytocin: co-evolution of human and domesticated animals
Published 2016-05-01“…At the behavioral level, OT facilitates intraspecific social contacts in mammals via various mechanisms ranging from the suppression of neuroendocrine stress responses to the direct OT action on neurons of socially relevant brain regions. …”
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7512
How journalism experience translates to social entrepreneurship: An intention formation study of the Art Yard at Dadaocheng in Taiwan
Published 2021-01-01“…Her entrepreneurial alertness and self-disciplined entrepreneurial self-efficacy originated from in-service education and inspiration through action. Social networks accumulated during her journalism career did not represent the primary source of support when establishing her social enterprise. …”
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7513
Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases
Published 2017-01-01“…This review summarizes the recent progress on the mechanisms of action of ROCK and their applications in disease treatment.…”
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7514
Brain Networks Connectivity in Mild to Moderate Depression: Resting State fMRI Study with Implications to Nonpharmacological Treatment
Published 2021-01-01“…The results demonstrate possible role of within-DMN and DMN-ECN functional connectivity in depression treatment and suggest that neural mechanisms of nonpharmacological treatment action may be unrelated to normalization of initially disrupted connectivity.…”
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7515
Controversies in the management of anti-TNF therapy in patients with Crohn’s disease: a Delphi consensus
Published 2024-01-01“…These statements cover: (1) use of first-line non-anti-TNF biological therapy; (2) role of HLA-DQA1*05 in daily practice; (3) attitudes in primary non-response and loss of response to anti-TNF therapy due to immunogenicity; (4) use of ustekinumab or vedolizumab if a change in action mechanism is warranted; (5) anti-TNF drug level monitoring; (6) combined therapy with an immunomodulator.Conclusion This document sought to pull together the best evidence, experts’ opinions, and treating physicians’ attitudes when using anti-TNF therapies in patients with CD.…”
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7516
CD109, a master regulator of inflammatory responses
Published 2025-02-01“…Exploration of CD109’s mechanisms of action will enhance our understanding of its contributions to disease pathology and its potential for therapeutic applications.…”
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7517
Selenium’s Role in Plant Secondary Metabolism: Regulation and Mechanistic Insights
Published 2024-12-01“…Although it has been shown that selenium can affect the antioxidant system and defense mechanisms in plants, detailed mechanisms of selenium’s action on plant secondary metabolic pathways, including its effects on specific metabolic enzymes and regulatory genes, still need to be revealed by further in-depth studies. …”
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7518
Mechanisms of RCD-1 pore formation and membrane bending
Published 2025-01-01“…Moreover, through AFM force spectroscopy and micropipette aspiration, we reveal that RCD-1 proteins bend membranes with low bending moduli. This combined action of pore formation and membrane deformation may constitute a conserved mechanism within the broader GSDM family.…”
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7519
Roxadustat improves diabetic myocardial injury by upregulating HIF-1α/UCP2 against oxidative stress
Published 2025-02-01“…This study explores the protective effect of FG-4592 on the diabetic myocardium and further investigates the specific mechanisms responsible for this action. Methods We established diabetic myocardial injury mice and high glucose-induced rat cardiomyocyte models, administered FG-4592 pretreatment to clarify the protective effects and related mechanisms of FG-4592 on diabetic myocardial injury by detecting changes in oxidative stress, mitochondrial function, and related pathways. …”
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7520
Technological Potential of Lactobacillus Strains Isolated from Fermented Green Olives: In Vitro Studies with Emphasis on Oleuropein-Degrading Capability
Published 2016-01-01“…B11 strain grown in a nutrient-rich medium showed a lower oleuropein-degrading action than when it was cultivated in nutrient-poor medium. …”
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