A systematic review of nanocarriers used in medicine and beyond — definition and categorization framework by Sabine Gressler, Christina Hipfinger, Florian Part, Anna Pavlicek, Christian Zafiu, Bernd Giese

“…Abstract Nanocarriers are transport and encapsulation systems that primarily serve to protect and improve the dispersibility of predominantly hydrophobic active ingredients but also enable their targeted delivery and controlled release at the site of action. Nanocarriers are mainly made of either organic or inorganic materials, but various combinations of materials in complex structures are also under development. …”
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Iguratimod prevents renal fibrosis in unilateral ureteral obstruction model mice by suppressing M2 macrophage infiltration and macrophage–myofibroblast transition by Yueyuan Zhou, Zhilan Li, Shenyi Yu, Xuan Wang, Tingting Xie, Weiru Zhang

“…Through ongoing exploration of its role and mechanisms of action, iguratimod has been observed to have antifibrotic effects in the lung and skin; however, its effect on renal fibrosis remains unknown. …”
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Low-Frequency rTMS over Contralesional M1 Increases Ipsilesional Cortical Excitability and Motor Function with Decreased Interhemispheric Asymmetry in Subacute Stroke: A Randomized... by Ka Yan Luk, Hui Xi Ouyang, Marco Yiu Chung Pang

“…The MEP (paretic hand) and interhemispheric asymmetry, Fugl-Meyer motor assessment, Action Research Arm Test, and box and block test scores improved more in the experimental group than controls at T1 (p<0.05). …”
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SELECTION OF EQUIPMENTFOR PROCESSING ANCIENT GRAINS by V. Petrov, A. Aleksashin, S. Pozner

“…Technological schemes with different peeling machines (peeling machine with abrasive discs, with rubber shafts, centrifugal action, impact peelers using a vibropneumatic table and friction separator) were analyzed, which have their own characteristics in separating peeled grain from unpeeled. …”
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The Role of Beta HPV Types and HPV-Associated Inflammatory Processes in Cutaneous Squamous Cell Carcinoma by Mircea Tampa, Cristina Iulia Mitran, Madalina Irina Mitran, Ilinca Nicolae, Adrian Dumitru, Clara Matei, Loredana Manolescu, Gabriela Loredana Popa, Constantin Caruntu, Simona Roxana Georgescu

“…In addition, the oncoproteins E6 and E7 of beta HPV types differ biochemically from their counterparts in the structure of alpha HPV types, resulting in different mechanisms of action in carcinogenesis. The aim of our manuscript is to present an updated point of view on the involvement of beta HPV types in cSCC pathogenesis.…”
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Mechanical Response of Surrounding Rock of Karst Tunnel under Stress-Damage-Seepage Coupling Effect by An Gang-jian, Cao Zheng-zheng, Duan Hong-fei, Li Guo-sheng, Li Ao

“…With the increase in γ, the area of the damage area in the upper part of the vault becomes larger, and most of the rock mass below the bottom plate is damaged; the damage area is semicircular, which indicates that both places are damaged by shearing action, resulting in the developed fissures. Besides, there are the distribution characteristics of “high value on both sides with a peak value and low value in the middle position” in the permeability distribution, and high permeability is located at the arch foot, and the low permeability is located at the floor. …”
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Decoding vascular aging: implications for atherosclerosis progression and clinical intervention by Silumbwe Ceaser Wankumbu, Xiao-Man Ji, Ming Xu

“…However, more than one specific action line is required to eradicate or slow down its manifestation. …”
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Optic Neuritis: From Magnocellular to Cognitive Residual Dysfunction by Anne-Claire Viret, Céline Cavézian, Olivier Coubard, Vivien Vasseur, Noa Raz, Netta Levin, Catherine Vignal, Olivier Gout, Sylvie Chokron

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Effect of laboratory aging on the performance of asphalt mixture containing high RAP content with the rejuvenator-loaded fiber by Yuxuan Sun, Fan Zhang, Augusto Cannone Falchetto, Di Wang

“…Finally, an Environmental Scanning Electron Microscope (ESEM) was utilized to analyze the distribution and action mechanisms of rejuvenator-loaded fibers within the asphalt mixture. …”
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Diverse Effects of Phytoestrogens on the Reproductive Performance: Cow as a Model by Izabela Wocławek-Potocka, Chiara Mannelli, Dorota Boruszewska, Ilona Kowalczyk-Zieba, Tomasz Waśniewski, Dariusz J. Skarżyński

“…In most of the cases, these chemicals are much less potent than endogenous estrogens but exert their biological effects via similar mechanisms of action. The most common source of phytoestrogen exposure to humans as well as ruminants is soybean-derived foods that are rich in the isoflavones genistein and daidzein being metabolized in the digestive tract to even more potent metabolites—para-ethyl-phenol and equol. …”
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Self-organized criticality and urban development by Michael Batty, Yichun Xie

“…This theory is called ‘self-organized criticality’; it is consistent with systems in which global patterns emerge from local action which is the hallmark of self-organization, and it is consistent with developments in system dynamics and their morphology which find expression in fractal geometry and weak chaos theory. …”
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Towards a European health information system: The BRIDGE Health, InfAct and PHIRI projects by Martin Thißen, Angela Fehr, Aline Anton, Stefanie Seeling, Thomas Ziese

“…Methods: This contribution describes the European projects BRIDGE Health (2015 – 2017), InfAct (Information for Action, 2018 – 2021) and PHIRI (Population Health Information Research Infrastructure, 2020 – 2023), which aimed at developing a sustainable health information infrastructure. …”
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A two-sex model for the influence of heavy alcohol consumption on the spread of HIV/AIDS by Gigi Thomas, Edward M. Lungu

“…In contrast to the result in some HIVvaccination models [52], backward bifurcation in our modelis not removed by replacing the corresponding standard incidencefunction with a mass action incidence, but is removed by merging thetwo susceptible classes of the same sex into one, i.e., by ignoringacquisition of, and ongoing recovery from, heavy-drinking habitsamong the susceptible population.…”
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Airway basal stem cell therapy for lung diseases: an emerging regenerative medicine strategy by Xingren Liu, Xin Wang, Xue Wu, Shuhua Zhan, Yan Yang, Caiyu Jiang

“…This review comprehensively explores the efficacy and action mechanisms of airway BSCs across various lung disease models and describes potential strategies for inducing pluripotent stem cells to differentiate into pulmonary epithelial lineages on the basis of the original research findings. …”
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Exploring the role and mechanisms of MAGEA4 in tumorigenesis, regulation, and immunotherapy by Weijian Zhu, Qiang Yi, Zheng Chen, Jiaqi Wang, Kui Zhong, Xinting Ouyang, Kuan Yang, Bowei Jiang, Jianing Zhong, Jinghua Zhong

“…This review summarizes the mechanisms of action, regulatory functions, and immunotherapeutic applications of MAGEA4 in cancer.MAGEA4 promotes tumor initiation and progression through multiple pathways, including ubiquitination and degradation of the tumor suppressor P53, regulation of cell cycle and apoptosis, modulation of DNA damage repair, and enhancement of cancer cell survival. …”
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Study on Mechanical Properties of Submunition’s Ribbon Straightening Section by Dong-ze Qin, Wei Zhang, Shu-Yun Zhang, Tian-Ji Guo, Shui-Yuan Pei, Jin-Shi Zhang

“…And the response characteristics of different material ribbon with different sizes of riveting holes and riveting joints under tensile action were simulated. The simulation results show that, in the trajectory environment with 30 m/s~55 m/s typical stream speed, the tensile force of the ribbon is less than 300 N, and the application concentration of the connecting parts of the riveting joint and the ribbon will not cause the failure of the kevlar ribbon, but it will cause the failure of the nylon ribbon. …”
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Examining the impact of a strength-based program to enhance teacher-trainees’ critical thinking abilities: a pilot study by Divya Surendran Nair, Seema Bhandare

“…The two-and-a-half-week strength-based program used the values in action survey to identify strengths. Pre- and post-test scores, measured with the Cornell Critical Thinking Test – Level Z, underwent Statistical Package for Social Sciences analysis including paired samples t-test for subcomponent and overall composite analysis. …”
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The Response of Sensitive LULC Changes to Runoff and Sediment Yield in a Semihumid Urban Watershed of the Upper Awash Subbasin Using the SWAT+ Model, Oromia, Ethiopia by Bekan Chelkeba Tumsa

“…The increases in sediment yields have serious implications for reservoir siltation downstream of the watershed and warn land use managers to take action.…”
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Synergism of d-limonene and temozolomide on migratory and apoptotic behaviors of human glioblastoma cell lines by Megha Gautam, Reema Gabrani

“…This study aims to assess the impact of combining DL with TMZ and explore its potential mechanism of action in U87MG and LN229 GBM cells. Methods: The effects of the combined treatment of DL and TMZ were assessed on various cellular aspects, including cell viability, anchorage-independent cell growth, and DNA damage. …”
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Study of some features of the foreign countries special police units activities by М. О. Borovyk

“…The latter involves the acquisition of knowledge of mine action, techniques for using a radio station, techniques of forced entry into the building and release of hostages, skills of extreme control and techniques of aiming fire at the vehicle, scuba diving techniques and express interrogation methods. …”
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