Plant thionins: structure, biological functions and potential use in biotechnology by T. I. Odintsova, M. P. Slezina, E. A. Istomina

“…Thionins protect plants from pathogenic bacteria and fungi acting directly on the membranes of microorganisms at micromolar concentrations, although their precise mode of action remains unclear. In addition to plant pathogens, thionins inhibit growth of a number of human pathogens and opportunistic microorganisms, such as Candida spp., Saccharomyces cerevisiae, Fusarium solani, Staphylococcus aureus and Escherichia coli. …”
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Analysis of Hydrogeochemical Characteristics of Tunnel Groundwater Based on Multivariate Statistical Technology by Chen Peng, Yuanming Liu, Huiyu Chen, Qiaowei Yuan, Qingzhi Chen, Shilong Mei, Zhonghu Wu

“…The results showed that water-rock action is the main mechanism controlling groundwater chemistry in the study area; HCO3-, Ca2+, and Mg2+ are associated with the widely distributed carbonate rocks in the study area. …”
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Developmental Programming in Response to Intrauterine Growth Restriction Impairs Myoblast Function and Skeletal Muscle Metabolism by D. T. Yates, A. R. Macko, M. Nearing, X. Chen, R. P. Rhoads, S. W. Limesand

“…Fetal adaptations to placental insufficiency alter postnatal metabolic homeostasis in skeletal muscle by reducing glucose oxidation rates, impairing insulin action, and lowering the proportion of oxidative fibers. …”
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Treatment with Herbal Formula Extract in the hSOD1G93A Mouse Model Attenuates Muscle and Spinal Cord Dysfunction via Anti-Inflammation by Eun Jin Yang, Sun Hwa Lee, Mudan Cai

“…Each bioactive component in such herbal combinations can exert a mechanism of action to increase therapeutic efficacy. Herein, we investigated the efficacy of an herbal formula, comprising Achyranthes bidentata Blume, Eucommia ulmoides Oliver, and Paeonia lactiflora Pallas, in suppressing the pathological mechanism of ALS in male hSOD1G93A mice. …”
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Evaluation of Preemergence Herbicide Programs for Control of Protoporphyrinogen Oxidase-Resistant Amaranthus palmeri in Soybean by Michael M. Houston, L. Tom Barber, Jason K. Norsworthy, Trent L. Roberts

“…At 28 DAT, treatments including mixtures of a very-long-chain fatty acid (VLCFA) plus the photosystem II- (PSII-) inhibiting herbicide metribuzin provided increased control over single herbicide sites of action (SOA) or herbicides mixtures to which Palmer amaranth was resistant. …”
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Deterioration of the Internal Structure of Loess under Dry-Wet Cycles by Wanjun Ye, Yang Bai, Chenyang Cui, Xu Duan

“…To understand the structural damage evolution process of loess under the action of dry-wet cycles, a triaxial test of a dry-wet cycle was performed by considering three influencing factors: initial moisture content, amplitude of the dry-wet cycle, and number of dry-wet cycles. …”
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Soil erosion by assessing hydrothermal conditions of its formation by A.B. Achasov, A.A. Achasova, A.V. Titenko

“…Formation of the soil’s natural profile on the slopes, caused by the action of natural factors of soil formation, can be described using a mathematical model, characterizing hydrothermal conditions of the slope areas through relative parameters of insolation (Ki) and moisture. …”
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Artificial intelligence-driven mobile interpretation of a semi-quantitative cryptococcal antigen lateral flow assay by David Bermejo-Peláez, Ana Alastruey-Izquierdo, Narda Medina, Daniel Capellán-Martín, Oscar Bonilla, Miguel Luengo-Oroz, Juan Luis Rodríguez-Tudela

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Hyperuricemia-induced complications: dysfunctional macrophages serve as a potential bridge by Wenyi Gu, Wenyi Gu, Jiajing Zhao, Yu Xu, Yu Xu, Yu Xu

“…The first mechanism involves direct action on urate transporters, such as URAT1 and ABCG2. …”
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The Antibiotic Knowledge, Attitudes, and Behaviors of Patients Purchasing Antibiotics without Prescription: Results of National Survey by Svetlana Rachina, Polina Zakharenkova, Roman Kozlov, Ivan Palagin, Daria Mamchich, Daria Strelkova

“…Knowledge on the mechanism of action and indications for the use of antibiotics was generally low. …”
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Geranylgeraniol (GGOH) as a Mevalonate Pathway Activator in the Rescue of Bone Cells Treated with Zoledronic Acid: An In Vitro Study by Riham M. Fliefel, Saleh A. Entekhabi, Michael Ehrenfeld, Sven Otto

“…Although the high concentration of ZA had significantly decreased the cell viability in the bone cells, GGOH reversed the action of ZA on the cells while at very high concentration; it caused severe reduction in the cell viability. …”
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Impact of phytochemical-based hydrocolloid dressings on wound healing: A comparative review by Sipho Sibanda, Mapula Razwinani, Keolebogile Shirley Motaung

“…In addition, the dressings significantly expedite wound healing offering a multifaceted approach because of the different mechanisms of action including antioxidant, anti-inflammatory and cell proliferation. …”
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The Mechanical Criterion of Activation and Instability of Normal Fault Induced by the Movement of Key Stratum and Its Disaster-Causing Mechanism of Rockburst in the Hanging Wall Mi... by Lyu Pengfei, Lu Jiabin, Wang Eryu, Chen Xuehua

“…The mechanical essence of fault rockburst was obtained as follows: under the action of fault, the static load of fault coal pillar was increased and superimposed with the fault activation dynamic load, leading to high-strength rockburst disaster. …”
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ANALYSIS OF RAINFALL ONSET, CESSATION AND LENGTH OF THE GROWING SEASON AND ITS VARIABILITY EFFECTS ON CROP PRODUCTION IN KARASUWA LOCAL GOVERNMENT AREA, YOBE STATE, NIGERIA by MOHAMMED BUKAR NGAMDU, Ahmadu Waibe GONI

“…The study recommend Farmers should change/shift their planting period to appropriate time since the onset date has changed in order to avoid crop damage at the early stage, Government should provide the farmers with early matured crop and improved crop varieties, mitigation/adaptation action is highly needed in order to cope with the problem. …”
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L’animation culturelle en mutation : une analyse diachronique des discours (2010-2024) / Changing sociocultural community development: A diachronic analysis of the articles (2010-2... by Jean-Marie Lafortune, Olivier Picard-Borduas

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LINC00707 Regulates miR-382-5p/VEGFA Pathway to Enhance Cervical Cancer Progression by Hua Guo, Jing Li, Furong Fan, Ping Zhou

“…Gain-of-function and loss-of-function assays revealed the function of LINC00707 in cervical cancer progression. In addition, the action of LINC00707 in cervical cancer cells was studied using bioinformatic tools and luciferase reporter experiment. …”
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Geochemical Characteristics of Crude Oil in Member 7 of Yanchang Formation in Yanchang Oilfield by Wenming Li, Zhendong Gao, Yongdong Wang, Jingyang Pu, Hanlie Cheng, Fahim Theon

“…The characteristics of crude oil and its maturity evaluation system are emphatically discussed, and the changes in crude oil characteristics under the action of microorganisms are comparatively studied. …”
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Network Pharmacology Analysis and Experimental Validation to Explore the Anti-inflammatory Mechanism of Asiatic Acid on Alcoholic Steatohepatitis by Tao Jiang, Jinhong Xu, Yang Lu, Xiaojin Chen, Yongxia Li

“…Objective. The mechanism of action of asiatic acid (AA) on alcoholic steatohepatitis (ASH) was investigated using network pharmacology and experiments. …”
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IUPHAR review: Drug repurposing in Schizophrenia – An updated review of clinical trials by Jihan K. Zaki, Jakub Tomasik, Sabine Bahn

“…A notable development is the combination of the muscarinic modulators xanomeline, a compound with antipsychotic properties, and trospium, included to mitigate peripheral side effects, now approved by the FDA as the first antipsychotic drug in decades with a fundamentally novel mechanism of action. Moving beyond the traditional dopaminergic paradigm of schizophrenia, such findings highlight opportunities to improve treatment-resistant symptoms and alleviate adverse effects. …”
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Progesterone Changes the Pregnancy-Induced Adaptation of Cardiomyocyte Kv2.1 Channels via MicroRNA-29b by Shuang Liang, Yu-Shuang Sun, Lu Li, Yao Long, Meng Wang, Hou-Zhi Yang, Chun-Di Li, Yan Wang, Shan-Shan Li, Xu Chen, Xin Jin

“…P4 administrations shortened the prolongation of QTC intervals and action potential duration (APD) that occurred during pregnancy, which was mainly attributable to the reduction in the voltage-gated potassium (Kv) current under basal conditions. …”
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