Insights into the mechanism of antiproliferative effects of primaquine-cinnamic acid conjugates on MCF-7 cells by Mabeta Peace, Pavić Kristina, Zorc Branka

“…To better understand the underlying mechanisms of action of these PQ-CADs, morphological studies of the effects of test compounds on MCF-7 cells were undertaken using haematoxylin and eosin stain. …”
Get full text

Balancing globalisation process through Development Agenda: sustainable global justice by S. M. Aamir Ali, A. Ghose

“…Although the concept of globalisation was initially intended to enhance the agency of developing nations, it has instead resulted in the erosion of their autonomy to independently determine their course of action. The democratic process has been impacted by the loss of decision-making power experienced by emerging countries as a consequence of globalisation. …”
Get full text

Late blight resistance of wild potato species under field conditions in the Northwest of Russia by N. M. Zoteyeva

“…Field resistance is considered to be more durable than those induced by the action of single R genes. To this end, resistance sources should be selected from а wide range of species under severe natural infection.Material and methods. …”
Get full text

N-Acetylcysteine Decreases Myocardial Content of Inflammatory Mediators Preventing the Development of Inflammation State and Oxidative Stress in Rats Subjected to a High-Fat Diet by Klaudia Sztolsztener, Wiktor Bzdęga, Katarzyna Hodun, Adrian Chabowski

“…The modulation of AA metabolism is a target for searching a therapeutic agent with potent anti-inflammatory action in cardiovascular disorders. Therefore, our study aims to determine the potential preventive impact of N-acetylcysteine (NAC) supplementation on myocardial inflammation and the occurrence of oxidative stress in obesity induced by high-fat feeding. …”
Get full text

Seismic Performance of Offshore Piers under Wave Impact and Chloride Ion Corrosion Environment by Yin Gu, Anhua Yu, Xiaolong Zhang

“…After 30 years of service, the lateral bearing capacity and stiffness of bridge piers are, respectively, reduced by 41.8% and 22.5% under the combined action of corrosion and HXB-5 wave impact. It is found that the coupling effects of multiple degradation factors were more significant than the simple superposition ones. …”
Get full text

Comparison between Vapocoolant Spray and Eutectic Mixture of Local Anesthetics Cream in Reducing Pain during Spinal Injections by Riyadh Firdaus, Besthadi Sukmono, Annemarie Chrysantia Melati, Berial Dewin Marzaini

“…However, this agent has delayed onset of action while vapocoolant spray serves more advantages. …”
Get full text

Emerging Roles of TRIM56 in Antiviral Innate Immunity by Dang Wang, Kui Li

“…We discuss the underpinning mechanisms of action and the questions that remain. Further studies understanding the complexity of TRIM56 involvement in innate immunity will add to critical knowledge that could be leveraged for developing antiviral therapeutics.…”
Get full text

Improving Accuracy of Malaria Diagnosis in Underserved Rural and Remote Endemic Areas of Sub-Saharan Africa: A Call to Develop Multiplexing Rapid Diagnostic Tests by Rasheed O. Makanjuola, Andrew W. Taylor-Robinson

“…As a means to combat this major global public health threat, rapid and effective diagnosis remains the frontline action to initiate a timely and appropriate medical intervention. …”
Get full text

Peripheral Nerve Regeneration with Acellular Nerve Allografts Seeded with Amniotic Fluid-Derived Stem Cells by Xue Ma, Eileen Elsner, Jiaozhong Cai, Thomas L. Smith, Zhongyu Li

“…The ANA plus AFS cell group also demonstrated greater gastrocnemius compound muscle action potential (CMAP) ratio, sciatic axon diameter, fiber diameter, myelin thickness, G ratio (average axonal diameter (AD)/fiber diameter (FD)), and neuromuscular junction (NMJ) numbers compared to ANA. …”
Get full text

Bibliometric analysis of prominent topics in global scientific production on sustainable development goals in Scopus (2013–2022) by Mario E. Diaz-Barrera, Crayla Alfaro-Aucca, Josmel Pacheco-Mendoza, Moisés Moreno-Albarrán, Edgard Fernando Pacheco-Luza, Carlos Enrique Rengifo Chunga

“…Abstract The Sustainable Development Goals (SDGs) are an action plan proposed by the United Nations to improve the quality of life of all people in the world by 2030. …”
Get full text

Peningkatan Hasil Pembelajaran Passing Bawah Bola Voli Dengan Pembelajaran berbasis gerak Manipulatif Menggunakan Bola by Faisal Setiawan Al-Majid, Bachtiar Bachtiar, Ahmad Alwi Nurudin

“…Bentuk penelitian ini adalah penelitian tindakan kelas (classroom action research). Populasi dari penelitian ini adalah siswa/I kelas VIII SMP N 10 Cibinong, dengan menggunakan tekhnik sampling jenuh. …”
Get full text

Colonel k. Škirpa's suggestion to guarrantee Lithuanian independence by Germany and the Soviet Union and their pledge to support Lithuania in her fight for Vilnius by Linas Locaitis

“…Škirpa not only discussed political problems that had arisen between Lithuania and Germany, but also spoke of a joint military action against Poland. He attempted to gain support from Germany and the Soviet Union in Lithuania's struggle to regain control of the Vilnius region. …”
Get full text

The Impact of Traffic-Induced Bridge Vibration on Rapid Repairing High-Performance Concrete for Bridge Deck Pavement Repairs by Wei Wang, Shuo Liu, Qizhi Wang, Wei Yuan, Mingzhang Chen, Xiaotian Hao, Shuai Ma, Xuanyu Liang

“…It is concluded that 1 d and 2 d compressive strength of HPC decreased significantly, and the maximum reduction rate is 9.1%, while 28 d compressive strength of HPC had a slight lower with a 3% maximal drop under the action of two simple harmonic vibrations with 2 Hz, 3 mm amplitude, and 4 Hz, 3 mm amplitude. …”
Get full text

Numerical modeling of wave-induced liquefaction around a gravity-based structure by V. S. Ozgur Kirca, V. S. Ozgur Kirca, Mert Angin, B. Mutlu Sumer

“…Once validated, the model was utilized to model the pore-water pressure buildup and residual liquefaction potential around a caisson breakwater under the action of standing waves and the wave-induced rocking motion of the caisson, separately and in combination. …”
Get full text

Decoding NAD+ Metabolism in COVID-19: Implications for Immune Modulation and Therapy by Shixu Song, Jialing Gan, Qiuyue Long, Zhancheng Gao, Yali Zheng

“…Future research should aim to unravel the intricate roles of key metabolites and enzymes in NAD+ metabolism and to elucidate their specific mechanisms of action. This will be essential for developing targeted NAD+ therapies, potentially transforming the management of COVID-19 and setting a precedent for addressing other infectious diseases.…”
Get full text

Characteristics of ChatGPT users from Germany: Implications for the digital divide from web tracking data. by Celina Kacperski, Roberto Ulloa, Denis Bonnay, Juhi Kulshrestha, Peter Selb, Andreas Spitz

“…In terms of political variables, political knowledge and political self-efficacy as well as some political behaviors such as voting, debating political issues online and offline and political action online were all associated with ChatGPT activity, with online political debating and political self-efficacy negatively so. …”
Get full text

A Roadmap Draft for the Development of Marine Regenerative Medicine in I.R. Iran by Mahdi Mahmoudpour, Iraj Nabipour

“…The first step is definition and scope of MRM; the second step shows the direction to MRM based on its structure and fundamental elements; the third step discloses the most competitive technologies in MRM; and the fourth step presents an investment summary and action plan for MRM in the I.R. Iran. Results: Five strategies may be considered for the development of MRM in I.R. …”
Get full text

Harnessing Biochar for Sustainable Horticulture: Strategies to Cope with Abiotic Stress by Matteo Lentini, Michele Ciriello, Youssef Rouphael, Emanuela Campana, Francesco Primo Vaccari, Stefania De Pascale

“…Considering the horticultural sector, this review also provides a comprehensive and detailed overview of how biochar positively influences growth, development, and yield by explaining the mechanisms and modes of action under both optimal growth conditions and unfavorable contexts (salt and water stress and the presence of heavy metals). …”
Get full text

Efficacy and Safety of Tracnil™ Administration in Patients with Dermatological Manifestations of PCOS: An Open-Label Single-Arm Study by Ezhil Arasan Ramanan, Sailatha Ravi, K. R. Radha Anbu, Margaret Michael

“…Therefore, we attribute the mechanism of action of Tracnil™ to modulation of receptor sensitivity to sex hormones or other downstream processing events. …”
Get full text

Analysis of a Methodology for Torsional Test under Normal Stress and Shear Performance for Asphalt Mixtures by Jun Xie, Yiqun Zhan, Yifan Wang

“…The torsional test method under normal stress formed a compression-shear action on the specimen by applying torque and normal stress and was used to evaluate the shear performance of the asphalt mixtures.…”
Get full text