Determination of mutagenicity of chemical compounds, physical factors and environmental pollutants by the Drosophila melanogaster wing somatic mutation and recombination test by L. P. Zakharenko, I. K. Zakharov

“…The Drosophila and mammalian detoxication system is arranged on similar principles, which are based on the action of cytochrome P450. There are modifications to SMART, based on elevated cytochrome P450 expression, allowing more reliable extrapolation of the test results to mammals. …”
Get full text

The meaning of the concept of “crime prevention in the customs sphere” by R. A. Cherkasskyi

“…According to the narrow understanding of crime prevention in the customs sphere, there is a set of preventive and educational measures, tools and methods used by specially authorized entities to minimize the action and complete “removal” of determinants of crime in the state, as well as building collective social awareness about the special negative nature of such determinants and intolerance to them. …”
Get full text

Efficacy of Telmisartan Plus Amlodipine in Nonresponders to CCB Monotherapy by Steen Neldam, Dingliang Zhu, Helmut Schumacher

“…Hypertensive patients unable to reach blood pressure (BP) targets with antihypertensive monotherapy may be switched to a combination of two medications with complementary modes of action for improved treatment response. This post hoc analysis pools data from 2812 patients, 1891 of whom were not at goal (diastolic BP [DBP] <90 mm Hg) with amlodipine 5 mg (A5) monotherapy who subsequently switched to telmisartan 40 or 80 mg (T80)/A5 single-pill combination (SPC) or amlodipine 10 mg (A10) monotherapy, and considers an additional 921 patients, 616 of whom were not at goal with A10 monotherapy who switched to telmisartan/amlodipine SPC. …”
Get full text

Auch eine Gewerkschaft? Der Deutschnationale Handlungsgehilfenverband und die Angestellten by Martin Otto

“…However, it acted like any union in terms of providing advice to its members and negotiating wage agreements, nor did it hesitate to initiate strike action. Already before the First World War, the DHV moved towards a more pragmatic position. …”
Get full text

Monitoring and quantification of rural urbanisation: Case of Arris and Theniet Elabed, Algeria by Soto Sabrina, Hamouda Abida, Rebah Halim

“…Regular monitoring of urban growth and updated data of the present state of land use are key steps for any action striving for sustainability in the Aurès region. …”
Get full text

Impact of Teaching Cohesive Devices to Iranian EFL learners: Case of IELTS writing task 2 examination by Syed Mojtaba Marashi

“…This research was an action research report of 10 students to make them better understand and answer writing tasks on IELTS test by employing probing techniques as one of test taking strategies. …”
Get full text

Topical issues of stimulating the work of civil servants by A. O. Ivanov

“…At the same time, such important elements of the mechanism of stimulating employment, such as guaranteed career growth, protection from administrative pressure and illegal disciplinary action, guaranteed application of incentives and rational organization of the work process, do not receive due attention and development. …”
Get full text

The communicative status of an individual in a digital society by Yu. A. Chernavin

“…This circumstance determines the attempt to study this phenomenon in its application to human communicative interactions, made in the article from the standpoint of the theory of communicative action. Identity processes and alienation processes, both generating and limiting, subordinating the communicative activity of the individual, are considered as the basis for the emergence of the communicative status of the individual. …”
Get full text

Role of phytochemicals in cardiovascular disease management: Insights into mechanisms, efficacy, and clinical application by Esther Ugo Alum

“…This review article aims to discuss phytochemicals in CVD management, including their mechanisms of action, benefits, and applications in detail. The review analyzes findings from clinical trials, epidemiological studies, and preclinical research to explain how these phytochemicals are effective in preventing and treating cardiovascular diseases. …”
Get full text

Experimental and Theoretical Investigations on Progressive Collapse Resistance of the Concrete-Filled Square Steel Tubular Column and Steel Beam Frame under the Middle Column Failu... by Wei Xuan, Lai Wang, Changjiang Liu, Guoqi Xing, Lili Zhang, Haitao Chen

“…The results indicated that the specimen collapse process includes the elastoplastic stage, plastic stage, transfer stage, and catenary stage, the beam mechanism and catenary mechanism were the principal mechanisms for the structure against progressive collapse, and catenary action can significantly strengthen structural resistance. …”
Get full text

Flow Field Simulation of Swirling Abrasive Jet Nozzle for Hard Rock Breaking by Zhang Dongqing, Li Jingbin, Hu Xiao, Liu Xin, Cheng Kang

“…Abrasive particles and water can acquire large tangential and radial velocity which can break rock under the action of shear and tensile stress efficiently. With the increase of the spinning angle, the axial velocity of the fluid decreases, and the tangential velocity increases gradually. …”
Get full text

EVALUATION OF THE EFFICIENCY OF THE DEVICE FOR LIMITING TENSION OF THE WIRE IN A SHORT CIRCUIT by I. I. Sergey, E. G. Panamarenka, Ya. A. Potachits

“…The intensity of the electrodynamic action of currents of a short circuit on the flexible conductors of overhead lines depends on the magnitude of currents of short-circuit. …”
Get full text

Effect of Phenylephrine on the Accommodative System by José J. Esteve-Taboada, Antonio J. Del Águila-Carrasco, Paula Bernal-Molina, Teresa Ferrer-Blasco, Norberto López-Gil, Robert Montés-Micó

“…Accommodation is controlled by the action of the ciliary muscle and mediated primarily by parasympathetic input through postganglionic fibers that originate from neurons in the ciliary and pterygopalatine ganglia. …”
Get full text

Modulatory effects of rutin on the expression of cytochrome P450s and antioxidant enzymes in human hepatoma cells by Karakurt Sedar

“…The flavonoid rutin was investigated for its anti-carcinogen and protective effects as well as modulatory action on CYPs and phase II enzymes in human hepatocellular carcinoma cells. …”
Get full text

Solution of Extraordinary Differential Equations with Physical Reasoning by Obtaining Modal Reaction Series by Shantanu Das

“…Extra Ordinary Differential equation Systems and its solution, with Physical Principle, of action-reaction and equivalent mathematical decomposition method, are obtained as an aid for Physicists and Engineers to tackle the process dynamics with ease. …”
Get full text

A new taxonomy of neuroprotective agents for stroke appropriate for the reperfusion era by Mersedeh Bahr-Hosseini, Jeffrey L. Saver

“…By focusing on broad physiologic targets of action rather than granular molecular mechanisms, this six-fold classification of neuroprotection can inform the design of preclinical studies and human clinical trials, including imaging biomarker endpoint selection and treatment timing. …”
Get full text

Assessment of Knowledge, Attitude, and Practice of Risky Sexual Behavior Leading to HIV and Sexually Transmitted Infections among Egyptian Substance Abusers: A Cross-Sectional Stud... by Atef Y. Bakhoum, Max O. Bachmann, Ehab El Kharrat, Remon Talaat

“…KAP average scores on safe sexual behavior were low compared to the maximum possible denoting low awareness and action of drug addicts towards avoidance of infection. …”
Get full text

Chemical compositions and health promoting effects of edible mushrooms from genus Russula by Xinwen Hu, Baojun Xu

“…Conclusion: Further research is warranted to uncover the underlying mechanisms of action and fully realize the clinical potential of Russula mushrooms in promoting human health and well-being.…”
Get full text

Identification of potential COVID-19 main protease inhibitors using structure-based pharmacophore approach, molecular docking and repurposing studies by Daoud Safa, Alabed Shada J., Dahabiyeh Lina A.

“…Our findings suggest an additional possible mechanism of action for remdesivir as an antiviral drug inhibiting COVID-19 Mpro. …”
Get full text

Effect and Removal Mechanisms of 6 Different Washing Agents for Building Wastes Containing Chromium by Wang Xing-run, Zhang Yan-xia, Wang Qi, Shu Jian-min

“…As per the results, particle size had little impact on the contents of total Cr and Cr (VI); after one washing with water, the removal rate of total Cr and Cr (VI) was 75% and 78%, respectively, and after the second washing with 6 agents, the removal rate of citric acid was the highest, above 90% for total Cr and above 99% for hexavalent chromium; the pH of building wastes were reduced by citric acid, and under acid condition, hexavalent chromium was reduced to trivalent chromium spontaneously by organic acid, which led to better removal rate of acid soluble Cr and reducible Cr; due to the complexing action, citric acid had best removal rate for oxidizable trivalent chromium. …”
Get full text