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6881
Marine Diterpenoids as Potential Anti-Inflammatory Agents
Published 2015-01-01“…However, more research is necessary to describe the mechanisms of action of these secondary metabolites. This review is a compilation of marine diterpenoids, mainly isolated from corals, which have been described as potential anti-inflammatory molecules.…”
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6882
Evolutionary Explanations of the “Actuarial Senescence in the Wild” and of the “State of Senility”
Published 2006-01-01“…For IMICAW, it should be substituted with the concept of a physiologic phenomenon genetically determined by a balance of opposite selective pressures — strictly in terms of kin selection — and, for “age changes”, with the action of the same IMICAW-causing mechanisms at ages when selection becomes ineffective.…”
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6883
Gastroscopy in Pediatric Surgery: Indications, Complications, Outcomes, and Ethical Aspects
Published 2015-01-01“…Furthermore, gastroscopies did not lead to any further action or change in treatment in 45% of gastroenterological conditions and 72% of GERD cases. …”
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6884
Therapy of Osteoporosis in Men with Teriparatide
Published 2011-01-01“…Osteoanabolic therapy is an attractive therapeutic option for men with osteoporosis because it directly stimulates bone formation, an action not shared by any antiresorptive drug. Teriparatide (recombinant human PTH(1-34)) and PTH(1-84) are available in many countries but PTH(1-84) is not available in the United States. …”
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6885
A Fixed-Time Zero Sequence Circulating Current Suppression Strategy Based on Extended Kalman Filter
Published 2025-01-01“…Firstly, the detailed mathematical model of ZSCC is described, where the inductance perturbations are considered according to the generation mechanism of ZSCC, and a novel ZSCC controller is designed based on the principles of the fixed-time stability theory which can assure the action time of the zero vectors in one switching cycle. …”
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6886
The Relationship between Academic Expectations Stress and Academic flow and Academic Hope in female students of the second year of high school
Published 2023-11-01“…Therefore, it is necessary to inform the parents and teachers of the students about the consequences of bad stress caused by academic expectations stress , and in this field, workshops should be held so that as a result of such an action, academic enthusiasm and academic hope in students Increase and reduce stress caused by academic expectations stress.…”
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6887
The use of medicinal plants and herbal medicines for patients in chemotherapy in an oncology center of Ijuí/RS
Published 2015-07-01“…For plants used in this study, there were no references to present scientific evidence of its pharmacological action for cancer treatment, proving the lack of education of the patients on medicinal plants. …”
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6888
BCL-2 inhibitors in hematological malignancies: biomarkers that predict response and management strategies
Published 2025-01-01“…In this article, we explain the role of BCL-2 family proteins in apoptosis and their mechanism of action that justifies their inhibition as a potential treatment target in B-cell malignancies, including chronic lymphocytic leukemia, multiple myeloma, B-cell lymphomas, but also AML. …”
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6889
Detection by Single-Cell RNA Sequencing of Virally Mediated Skin Diseases
Published 2025-05-01“…However, their role and precise mechanism of action in other skin diseases remain unknown. We describe a single-cell RNA-sequencing–based strategy to interrogate human skin biopsies for viral transcripts, permitting detection of viral infection within a sample, single-cell resolution of virally infected cells and identification of subsequent transcriptomic perturbations. …”
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6890
Amentoflavone from Selaginella bryopteris leaf extracts modulate MAPK signaling - Molecular modeling study for therapeutic target analysis
Published 2025-05-01“…Subsequent research aims to characterize individual bioactive phytochemicals and their mode of action for possible pharmacological application.…”
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6891
Factors Influencing Brucellosis Preventive Behaviors among Marginalized Iranian Women: An Application of the Health Belief Model
Published 2022-01-01“…The results showed that one unit rise in the scores of knowledge, self-efficacy, and cues to action resulted in an increase in the mean score of the protective behavior by 0.189, 209, and 0.150, respectively. …”
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6892
The impact of innate immune response on the efficacy of oncolytic viruses
Published 2024-12-01“…The proposed mechanism of action of various oncolytic viruses has initially been explained by the ability of such viruses to selectively lyse tumor cells without damaging healthy ones. …”
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6893
RECONSTRUCTION OF MECHANISMS REGULATING THE EXPRESSION OF THE ESCHERICHIA COLI YFIA GENE UNDER STRESS CONDITIONS
Published 2014-12-01“…Simulation of the response of E. coli cells transformed with pYfi-gfp plasmid to oxidative stress indicated that the maximum agreement with experimental data was achieved in a model implying a complex action, apparently mediated by several transcription factors (TFs). …”
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6894
Dental Mesenchymal Stem/Stromal Cells and Their Exosomes
Published 2018-01-01“…Furthermore, the therapeutic potential of DP-MSCs is realized through paracrine action of extracellularly released components, for which exosomes play an important role. …”
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6895
South Africa and Sweden in the UN Security Council
Published 2023-02-01“…The permanent five (P5) members control the Council’s agenda and block action on conflicts because of their own national interests and geopolitical rivalries. …”
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6896
Methods of forensic examination of Nalbuphine
Published 2024-03-01“…In terms of pharmacological action, it belongs to the group of opioid receptor agonists-antagonists (pentazocine, buprenorphine, butorphanol). …”
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6897
Comparing the Efficacy of Excitatory Transcranial Stimulation Methods Measuring Motor Evoked Potentials
Published 2014-01-01“…Different time courses of the applied stimulation methods suggest different underlying mechanisms of action. Better understanding may be useful for better targeting of different transcranial stimulation techniques.…”
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6898
Current status and potential of bacteriocin-producing lactic acid bacteria applied in the food industry
Published 2025-01-01“…Accordingly, the capacity of LAB to produce bacteriocin in the aspects of classifications, mode of action, biosynthesis mechanisms are introduced, which leads to further consideration of the current status and potential values of bacteriocin-producing LAB applied in the food industry. …”
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6899
Study on Seismic Response Characteristics of Shield Tunnel in Soil-Rock Combination Stratum
Published 2022-01-01“…The results revealed the following: (1) the peak bending moment distribution diagram derived from numerical calculation is consistent with that obtained from the shaking-table model test, which has shown that the numerical and experimental methods are correct, and the research results are available for the seismic resistance of shield tunnels. (2) The deformation, axial force, shear force, and bending moment of the tunnel structure in the soil-rock combination stratum under the action of S-wave change abruptly and significantly at the soil-rock interface section, and the difference in structural stress between the upper and lower sides of the soil-rock interface increased by 65.5%. …”
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6900
Study on Susceptibility and Mechanism of Reheat Cracking in Welded Joint of Type 347 Austenitic Stainless Steel
Published 2022-01-01“…Since there is a high welding residual stress in welded joints, cavities are formed under the action of the stress at a high temperature, and the merging of cavities causes the formation of cracks which extend along the grain boundary.…”
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