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6441
Advancements in electron paramagnetic resonance (EPR) spectroscopy: A comprehensive tool for pharmaceutical research
Published 2024-12-01“…We detail how EPR spectroscopy can be employed to assess free radical scavenging properties in pharmaceutical compounds, elucidate drug mechanisms of action, and explore pharmacokinetics. Additionally, we investigate the role of free radicals in drug-induced toxicity and drug-membrane interactions, while also covering the application of EPR spectroscopy in drug delivery research, advanced studies of metallodrugs, and monitoring of oxygen levels in biological systems through EPR oximetry. …”
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6442
Pirfenidone: An Encouraging Therapeutic Approach For Enhancing Lateral Spinothalamic Tract Function After Spinal Cord Compression Injury
Published 2024-06-01“…Conclusion: Pirfenidone with its anti-fibrotic and anti-inflammatory action, is likely to enhance the functionality of the lateral spinothalamic tract following spinal cord injury. …”
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6443
Aspectos morfológicos in vivo e in vitro de fibroblastos gingivales en pacientes con agrandamiento gingival
Published 2020-01-01“…Para este fin, fueron empleados los anticuerpos anti-actina y anti-vimentina. En los pacientes con AG por ortodoncia fue observado tejido epitelial con acantosis e hiperqueratinizado, acompañado de red compacta de fibras de colágeno. …”
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6444
Two-Dimensional Cutting (TDC) Vitrectome: In Vitro Flow Assessment and Prospective Clinical Study Evaluating Core Vitrectomy Efficiency versus Standard Vitrectome
Published 2016-01-01“…Vitrectomy surgery performed using a TDC vitrectome was faster than core vitrectomy utilizing a standard single-action vitrectome at similar cut speeds.…”
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6445
Investigating Non-steroidal Anti-Inflammatory Drugs as Potential Cancer Adjuncts: A Novel Approach to Cancer Therapy
Published 2025-02-01“… Purpose: This review aims to evaluate the chemo preventive and therapeutic potential of non-steroidal anti-inflammatory drugs (NSAIDs) in cancer management, emphasizing their mechanisms of action and clinical relevance. Background: Cancer is a leading cause of mortality worldwide, prompting the need for innovative treatments. …”
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6446
Ambivalent partnership of the Drosophila posterior class Hox protein Abdominal-B with Extradenticle and Homothorax.
Published 2025-01-01“…Most of our current knowledge of Hox protein specificity stems from the study of anterior and central Hox proteins, identifying the molecular and structural bases for Hox/Pbc/Meis-Prep cooperative action. Posterior Hox class proteins, Abdominal-B (Abd-B) in Drosophila and Hox9-13 in vertebrates, have been comparatively less studied. …”
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6447
Procrustes' Bed Metaphor: Understanding the Problem of Creativity and Innovation in the Human Resources of Iran's State-Owned Enterprises
Published 2023-11-01“…Questionnaires were distributed among experts and experts in charge of five big-size state-owned companies, and finally, 124 questionnaires were analyzed descriptively.Findings: The research findings show that the Procrustes bed has become a company desk in Iran's state-owned enterprises. The freedom of action to present creative and innovative ideas, the possibility of implementing innovative ideas, welcoming new ideas, supportive management, offering rewards to new ideas, and overall satisfaction with the current state are unfavourable.Originality/Value: Following the social sciences and especially structuring and problem-solving approaches, we believe that knowing the problem is the first and most crucial step in solving a problem. …”
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6448
PARAMETRIC AMPLIFICATION OF THE SIGNALS IN THE ELECTROSTATIC GRAVIINERTIAL SENSOR
Published 2017-06-01“…PM makes small rotations under the action of gravitational forces or inertial forces.The distinctive features of the sensor are that the differential electrostatic system provides simultaneous reading of the desired signal and a control the torsional rigidity of suspension. …”
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6449
Concise Review: Mesenchymal Stem Cells Ameliorate Tissue Injury via Secretion of Tumor Necrosis Factor-α Stimulated Protein/Gene 6
Published 2014-01-01“…This important mechanism of action has attracted increasing attention, and therefore we conducted this review to summarize the latest research.…”
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6450
Steady Wind Load on External Surface and Its Effect on Wind-Induced Response for a 200 m High Natural-Draught Cooling Tower
Published 2021-01-01“…Moreover, the wind-induced static responses of the tower under the action of the realistic pressure distribution Cp(θ, z) and the simplified approach Cp(θ) are basically consistent, because the wind load distribution is more important than its magnitude for the wind-induced response of cooling tower, and the wind-induced response of the cooling tower is dominated by the local shell deformation.…”
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6451
Analysis of Coupling Effect and Heavy Load of High-Temperature Stability of Asphalt Mixture
Published 2022-01-01“…The APA test results, which were used to evaluate the anti-rutting performance of the asphalt mixture on the basis of the ratio of the rutting depth difference to action times from 6000 to 8000, showed a good correlation with the CLWT test results. …”
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6452
Cordyceps militaris solid medium extract alleviates lipopolysaccharide-induced acute lung injury via regulating gut microbiota and metabolism
Published 2025-01-01“…Therefore, CMME may improve lung injury by regulating intestinal flora and correcting metabolic disorders, providing new insights into its mechanism of action.…”
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6453
Upaya Meningkatkan Kecerdasan Visual Spasial Anak Usia Dini melalui Bermain Tebak Gambar
Published 2024-06-01“…Based on teacher research in a learning process lacking the method of playing guessing pictures in improving the development of children's spatial-visual intelligence, a class action research method (PTK) was used in the research. …”
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6454
Context-dependent modulation of spatial attention: prioritizing behaviourally relevant stimuli
Published 2025-02-01“…Over time, we learn to allocate attention resources towards stimuli that are behaviourally relevant to ongoing action, leading to attention capture by meaningful peripheral stimuli. …”
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6455
Functional Development of the Human Gastrointestinal Tract: Hormone- and Growth Factor-Mediated Regulatory Mechanisms
Published 2004-01-01“…These new cells lines could serve important applications in the study of pathogenic action and epithelial regeneration.…”
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6456
Potential Use of Euphorbia hirta for Dengue: A Systematic Review of Scientific Evidence
Published 2018-01-01“…Hence, well-controlled clinical trials and contemporary pharmacological approaches including activity guided fractionation and elucidation of the mode of action are encouraged to establish the use of E. hirta for dengue.…”
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6457
IMPROVING STUDENT LEARNING OUTCOMES THROUGH THE IMPLEMENTATION OF DIFFERENTIATED LEARNING IN A PROBLEM-BASED LEARNING MODEL
Published 2024-07-01“…The aim of this research is to determine the extent to which students' learning outcomes have improved through the application of differentiated learning in a Problem-Based Learning (PBL) model in the Economics subject. The study employs a action research, consisting of two cycles, beginning with a pre-cycle. …”
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6458
Towards Enhancement of Performance of K-Means Clustering Using Nature-Inspired Optimization Algorithms
Published 2014-01-01“…The algorithms help speed up the clustering process by converging into a global optimum early with multiple search agents in action. Inspired by nature, some contemporary optimization algorithms which include Ant, Bat, Cuckoo, Firefly, and Wolf search algorithms mimic the swarming behavior allowing them to cooperatively steer towards an optimal objective within a reasonable time. …”
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6459
Students’ attitudes to social advertising: results of a study
Published 2023-06-01“…The study results indicate that, firstly, most young people are ready to help shelters and foundations that support to homeless animals, however, young people are not ready to make an effort to find the necessary information; secondly, young people do not always notice social advertising, despite the fact that they actively use different media channels; thirdly, according to respondents, the most effective social advertising contains in the verbal or visual series direct encouragement to the target action; fourthly, in order to increase the level of involuntary attention of target groups to social advertising, it is necessary to use new techniques of visual impact on the audience using digital technologies. …”
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6460
The Rise and Fall of the Iraqi Sunni Awakening Movement
Published 2023-03-01“…The article studies the rise of the Sunni Awakening (or Sahwa) movement as an example of how different groups can be mobilized for collective action and disintegrated by internal and external factors. …”
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