Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy by Tom Verfaillie, Maria Salazar, Guillermo Velasco, Patrizia Agostinis

“…Recently, a variety of anticancer therapies have been linked to the induction of ER stress in cancer cells, suggesting that strategies devised to stimulate its prodeath function or block its prosurvival function, could be envisaged to improve their tumoricidial action. A better understanding of the molecular mechanisms that determine the final outcome of UPR and autophagy activation by chemotherapeutic agents, will offer new opportunities to improve existing cancer therapies as well as unravel novel targets for cancer treatment.…”
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ON DIGNITY, VULNERABILITY, INDIGENOUS PEOPLES AND FISHERFOLKS: CHILEAN SUBSISTENCE FISHING ACCORDING TO INTERNATIONAL HUMAN RIGHTS by Eduardo Roig Monge

“…But, above all, they introduce protection standards that allow us to see such legislation not as a mere derivation of state privilege, but as an attempt to foster a situation of equality: an affirmative action. We conclude by presenting a conceptual approach for Chilean subsistence fishing, suggesting that it could help to unveil new objectives and rights in fishing, and even influence the understanding of natural resource allocation.…”
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A Review: Inflammatory Process in Alzheimer's Disease, Role of Cytokines by Jose Miguel Rubio-Perez, Juana Maria Morillas-Ruiz

“…By contrast, other cytokines such as IL-1 receptor antagonist (IL-1ra), IL-4, IL-10, and transforming growth factor (TGF)-β can suppress both proinflammatory cytokine production and their action, subsequently protecting the brain. It has been observed in epidemiological studies that treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) decreases the risk for developing AD. …”
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Functional Multipotency of Stem Cells: What Do We Need from Them in the Heart? by Pablo Díez Villanueva, Ricardo Sanz-Ruiz, Alberto Núñez García, María Eugenia Fernández Santos, Pedro L. Sánchez, Francisco Fernández-Avilés

“…Nevertheless, a complete knowledge on the mechanisms of action of stem cells still remains elusive. Of the three main mechanisms by which stem cells could exert their benefit, paracrine signaling from the administered cells and stimulation of endogenous repair are nowadays the most plausible ones. …”
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Missed, but Momentous: A Comprehensive Review of Neglected Tropical Skin Diseases in Southern India and their Global Impact by Ramesha M Bhat, N Swathi

“…This systematic review aims to probe into the intricate facets of NTDs in South India, delving into each dermatological NTD in detail, spotlighting their essence, prevalence, socio-economic reverberations, hurdles, and the necessity for collective action. By prioritizing NTD control in South India, we can collectively alleviate local suffering and contribute to global health security and equity, charting a course toward a healthier, more resilient world.…”
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Caesarean Delivery Complicated by Unintentional Subdural Block and Conversion Disorder by Hesham Elsharkawy, Ashish K. Khanna, Sabri Barsoum

“…Subdural block is also a potential but rare complication of attempted epidural placement during a CSE procedure, which may present as a block that is usually patchy in nature, with a component of sensory and/or motor deficit and a variable duration of action. In addition, a conversion disorder or a functional neurological disorder has been described with epidural and spinal anesthesia in obstetric patients. …”
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Numerical Investigation on Pressure Pulsation Characteristics and Radial Force of a Deep-Sea Electric Lifting Pump at Off-Design Conditions by Yajuan Kang, Shaojun Liu, Weisheng Zou, Xiaozhou Hu

“…To predict the vibrational conditions, the generation mechanism, and action law of pressure pulsation and radial force, a computational fluid dynamics (CFD) study of a deep-sea electric lifting pump operating under different off-design conditions was performed. …”
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University Philosophy Course: Reboot is Required by M. D. Shchelkunov

“…In this case, the philosophical content becomes a tool to achieve this goal, and the philosophical heritage is used as a theoretical basis for mastering the technologies of mental action. The article presents the experience of Kazan University, where the philosophy course has recently become a tool for “system and critical thinking” competence training. …”
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Combined Use of Clips and Nylon Snare (“Tulip-Bundle”) as a Rescue Endoscopic Bleeding Control in a Mallory-Weiss Syndrome by Hrvoje Ivekovic, Bojana Radulovic, Suzana Jankovic, Pave Markos, Nadan Rustemovic

“…However, no strict recommendations exist in regard to the mode of action after a failure of primary endoscopic hemostasis. …”
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An Overview of the Utilization of Common Waste as an Alternative Fuel in the Cement Industry by Tee How Tan, Kim Hung Mo, Jiayi Lin, Chiu Chuen Onn

“…A significant amount of the cost of cement production, ranging from 20% to 25%, is attributed to thermal energy. In addition, the action of mining and burning fossil fuels results in the unfavorable emission of hazardous compounds into the environment. …”
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A Deep Q-Network-Based Collaborative Control Research for Smart Ammunition Formation by Jian Shen, Benkang Zhang, Qingyu Zhu, Pengyun Chen

“…Then, the basic framework ε-imitation action-selecting strategy and the algorithm details were developed to address the SAF control problem based on the DQN scheme. …”
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Neurosurgical aspects of marble bone disease: treatment modalities and outcome by Mahmoud Mohammed Gamal, Roshdy Elkhayat, Hassan Mohammed Hassan

“…Abstract Background Marble bone disease or osteopetrosis is an extremely rare hereditary condition that causes abnormal bone density and fragility due to impaired osteoclastic action. This causes the body to produce an abnormal amount of bone that are evident in radiographic findings and cause problems with the body systems, particularly the nervous system. …”
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Xylanase-Producing Microbes and Their Real-World Application by Milan Phuyal, Uttam Budhathoki, Durga Bista, Shailendra Shakya, Rajan Shrestha, Ashwinee Kumar Shrestha

“…The present study is focused on the availability of microbial sources capable of producing xylanase, a hemicelluloses-degrading enzyme with multiple modes of action along with specificity, and their real-world applications. …”
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Modern options of prokinetics in gastroesophageal reflux disease treatment by A. A. Sheptulin, A. A. Kurbatova, S. A. Baranov

“…GERD belongs to acid-related diseases, because detrimental action of hydrochloric acid on esophageal mucosa plays major role in its pathogenesis. …”
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Institutional Components Affecting the Internationalization of Higher Education: A Case Study on Estonia by Joamets Kristi, Vasquez Maria Claudia Solarte

“…This paper argues that establishing clear definitions, priorities and coordinated action plans involving key stakeholders could enhance the formulation of more feasible and impactful regulatory strategies, facilitating a smooth internationalization in the European Higher Education Area (EHEA). …”
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Bound states of massive complex ghosts in superrenormalizable quantum gravity theories by M. Asorey, G. Krein, M. Pardina, I. Shapiro

“…Abstract One of the remarkable differences between renormalizable quantum gravity with four-derivative action and its superrenormalizable polynomial generalizations is that the latter admit a more sophisticated particle mass spectrum. …”
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The Effect of Active-Participant Experiments upon the Skills of Nursery Class Students to Recognize Measuring Instruments by Ozkan Sapsaglam, Aykut Emre Bozdogan

“…The objective of this study is to determine the effect of active-participant experiments upon the skills of preschool children to recognize and accurately select measuring instruments that are encountered in daily life and used in measuring various magnitudes. In the study, action research method was used. The study was conducted in the school year of 2015-2016 with totally 19 children (8 male and 11 female) aged 48-60 months. …”
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The implementation of TPS (think pair share) cooperative learning model aided by Google hangouts in literary expression course by Fina Hiasa, Supadi Supadi, Nafri Yanti

“…The data analysis technique used in this study was a descriptive method that produced an overview of the extent to which the quality of learning has improved by using the TPS (Think-Pair-Share) type of cooperative learning model assisted by Google Hangouts for students who were the research samples. This classroom action research was carried out in two cycles, and each cycle used the main digital learning room, namely the Google Hangout application. …”
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Cyclic and Explosive Evaluation of New Proposed Steel Joint by Iman Faridmehr, Yusof Ahmad, Mahmood Md. Tahir, Mohd Hanim Osman

“…Besides, the new proposed connection developed adequate catenary action, which is a fundamental criterion to resist against progressive collapse. …”
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Strength and Solidification Mechanism of Silt Solidified by Polyurethane by Fengyuan Li, Chaojie Wang, Yangyang Xia, Yanjie Hao, Peng Zhao, Mingsheng Shi

“…The X-ray diffraction (XRD) and energy-dispersive spectroscopy (EDS) have proven that polyurethane does not react with the silt, but they could improve the strength of the silt through physical action. Mercury intrusion porosimetry (MIP) and scanning electron microscopy (SEM) were performed to find that polymers can reduce soil porosity, and the addition of polyurethane improved the strength of the silt mainly through adhesion, wrapping, filling, and bridging.…”
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