Research progress of HIF-1a on immunotherapy outcomes in immune vascular microenvironment by Shaoyan Shi, Xuehai Ou, Chao Liu, Hao Wen, Jiang Ke

“…This review explores the molecular mechanisms of action of HIF-1α in IVM, its impact on immunotherapy resistance, as well as potential interventions, emphasizing the need for innovative approaches to circumvent hypoxia-driven immunosuppression in cancer therapy.…”
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Dynamic Response of Rock Slopes under Obliquely Incident Seismic Waves by Biao Liu, Boyan Zhang

“…The research results can provide some basis for the pseudostatic method to determine the seismic action coefficient.…”
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Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I by Bryan Neumann, Stephen McCarthy, Shane Gonen

“…Abstract Voltage-gated sodium channels (NaVs) selectively permit diffusion of sodium ions across the cell membrane and, in excitable cells, are responsible for propagating action potentials. One of the nine human NaV isoforms, NaV1.8, is a promising target for analgesics, and selective inhibitors are of interest as therapeutics. …”
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Seismic Performance of a Corroded Reinforce Concrete Frame Structure Using Pushover Method by Meng Zhang, Ran Liu, Yaoliang Li, Guifeng Zhao

“…At the same time, the formation and development of plastic hinges (beam hinges or column hinges) will accelerate, which leads to a more aggravated deformation of the structure under rare earthquake action, resulting in a negative effect to the seismic bearing capacity of the structure.…”
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Julien Pharo, Démocratie d’entreprise et fiscalité. Enjeux théoriques et pratiques de la mise en place d’une fiscalité incitative procédurale by Julien Pharo

“…This thesis has enabled us not only to re-examine the possibility of public action to democratise business, but also to question the meaning of tax incentives from the point of view of the public authorities. …”
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Study of the Boson Peak and Fragility of Bioprotectant Glass-Forming Mixtures by Neutron Scattering by F. Migliardo, S. Magazù, M. A. Gonzalez, C. Mondelli

“…The data analysis allows determining the Boson peak behavior and discussing the findings in terms of fragility in relation to the bioprotective action of trehalose and glycerol.…”
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IMF Sovereign Debt Restructuring Framework: Origin, Evolution and Latest Updates of its Main Components by Alejandro Gabriel Manzo

“…To this end, the article analyzes: 1) the framework substantial and procedural rules in order to show it as an abstract normative structure as well as an action procedure applicable to specific cases; 2) the framework evolution, synthetically presenting the discussions that gave rise to its main components and justified its principal changes; 3) the framework latest updates, which modified sensitive areas of the Fund’s surveillance and financing functions. …”
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DEVELOPMENT OF A PROJECT BASED ONLINE LEARNING MODEL TO IMPROVE THE SKILLS AND ABILITIES OF ACTORS FOR STUDENTS by Welly Suryandoko

“…Based on the assessment of project-based online learning validators, the results of action on content suitability are high criteria, and aspects of construction and readability are very high.…”
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WOMEN PARTICIPATION IN POLITICS: THE NIGERIAN AND ANGOLA EXPERIENCE by EDIBA SABASTINE, UMAR SULEIMAN ZAKARI, GEOFFREY NANBAL SHIPURUT

“…The paper therefore recommends strengthening the implementation and enforcement of affirmative action measures, such as gender quotas, at all levels of government and across all branches of power. …”
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RNA structure in alternative splicing regulation: from mechanism to therapy by Bao Nengcheng, Wang Zhechao, Fu Jiayan, Dong Haiyang, Jin Yongfeng

“…The principal mechanisms of action behind this phenomenon are described, followed by a discussion of prospective development strategies and pertinent challenges.…”
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Société du risque, environnement et potentialisation des menaces : un défi pour les sciences sociales by Lionel Charles, Bernard Kalaora

“…Because of the lack of pragmatism and opening to the unpredictability of social action, French society overreacts to threats understood as a breach to its preemption of certainty and its assertion of mastery. …”
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Relativistic Einstein rings of Reissner–Nordström black holes nonminimally coupled to electrodynamics by Rodrigo Maier

“…Starting from a general action of a nonminimal coupled electrodynamics we show that an unstable effective photon sphere may be obtained in the regime of eikonal approximation. …”
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Acceleration Feedback-Based Active and Semi-Active Seismic Response Control of Rail-Counterweight Systems of Elevators by Rildova, M.P. Singh

“…The only way a control action can be applied to a moving counterweight-rail system is through a mass damper placed in the plane of the counterweight. …”
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Tropical Fruit Pest Management Strategic Plan (PMSP) by Mark A. Mossler, Olaf Norman Nesheim

“…There are several areas of action which seem to be common to the tropical fruits in general. …”
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Long-Term Exploitation of a Flexible Foundation in Conditions of Nonlinear Rheological Deformation under Force and Non-Force Influences by M. V. Berlinov

“…The possibility of considering the processes of long-term deformation of rein-forced concrete under a changing mode of action of an external load based on the method of integral estimates is shown. …”
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Vernacular Architecture as Self-Determination: Venturi, Scott Brown and the Controversy over Philadelphia's Crosstown Expressway, 1967-1973 by Sebastian Haumann

“…Embedding the discussion on architectural theory in the concrete context of urban history reveals important links between intellectual discourse and political action. Venturi and Scott Brown’s repeated reference to social aspects of architecture can only be understood, so this article demonstrates, if we analyse the concrete engagements in which they developed their projects. …”
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Increase in treatment compliance reveals new options of treatment of gastroesophageal reflux disease by Yu. V. Yevsyutina, A. S. Trukhmanov

“…Existing PPIs have some limitations — necessity of intake strictly before meal and short action period. Dexlansoprazole in double delayed release form allows intake without relation to food intake that allows to increase compliance to treatment.Conclusion. …”
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Cardiac Expression of Tnnt1 Requires the GATA4-FOG2 Transcription Complex by Nikolay L. Manuylov, Sergei G. Tevosian

“…Since the myocardial-restricted Fog2 re-expression in the Fog2 null embryos is sufficient to extend their life span, identification of GATA4-FOG2 target genes in cardiomyocytes could shed light on the molecular mechanism of GATA4-FOG2 action in these cells. We report here that cardiac expression of slow skeletal troponin T (Tnnt1) strictly depends on the physical interaction between GATA4-FOG2 in the myocardium of both atria and ventricles.…”
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Vulnérabilité du territoire littoral guyanais aux maladies infectieuses à transmission vectorielle : esquisses de problématiques et perspectives de recherches pluridisciplinaires... by Valérie Morel

“…The study of territorial vulnerability of French Guiana to VBD opens new possibilities of action for the management of health risks.…”
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PENGGUNAAN STRATEGI INKUIRI DALAM PEMBELAJARAN KOOPERATIF UNTUK MENINGKATKAN HASIL BELAJAR SISWA KELAS VIII A DI SMPN I GENENG NGAWI TAHUN AJARAN 2008 / 2009 by Andrias Marsanto

“…Research methods using action research, research subjects 40 students VIIIA. …”
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