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Discovery of the bacterial HslV protease activators as lead molecules with novel mode of action
Published 2025-02-01Get full text
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463
Real-time multimodal imaging of daptomycin action on the cell wall of adherent Staphylococcus aureus
Published 2025-02-01“…Results description Daptomycin, at clinically relevant concentrations, rapidly eradicated adherent bacteria in the exponential growth phase, demonstrating an efficiency comparable to its action against planktonic cells. Prolonged exposure to the antibiotic caused marked alterations in the bacterial cell wall, including surface roughening and perforation, as revealed by multimodal imaging. …”
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464
Selective Serotonin Reuptake Inhibitors: Antimicrobial Activity Against ESKAPEE Bacteria and Mechanisms of Action
Published 2025-01-01“…Regarding their mechanisms of action as antibacterials, for the first time, increased membrane permeability was detected, as evidenced by heightened dye absorption, along with the increased presence of total proteins and dsDNA in the extracellular medium of <i>Escherichia coli</i> ATCC2 25922 and <i>Staphylococcus aureus</i> ATCC 25923, and oxidative stress was also detected in bacteria treated with sertraline and paroxetine, with reduced efficiency observed in the presence of antioxidants and higher levels of oxygen-reactive species evidenced by their reaction with 6-carboxy-2′,7′-dichlorodihydrofluorescein diacetate. …”
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465
A review on mechanisms of action of bioactive peptides against glucose intolerance and insulin resistance
Published 2022-11-01“…Reviews on the mechanisms of action of bioactive peptides on glucose homeostasis and insulin resistance are scarce. …”
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466
Action potential-like modes as modulated waves in an extended soliton model for biomembranes and nerves
Published 2025-01-01“…By extending the Heimburg–Jackson soliton model for neural signals that considers the effects of higher-order nonlinearities, the dynamics of modulated waves characterizing electromechanical density pulses is described in the form of soliton-like pulse signals representing nerve impulses, well-known as action potential pulses (Appulses). The investigation is performed both analytically and numerically, where a comprehensive picture of higher-order nonlinearities effects on the generation and evolution of nerve impulses is provided. …”
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467
Pause before action: Waiting short time as a simple and resource-rational boost
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468
Research Progress on the Preparation, Physiological Activity and Action Mechanism of Plant Derived Bioactive Peptides
Published 2025-02-01Subjects: Get full text
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469
The action of pseudo-differential operators on functions harmonic outside a smooth hyper-surface
Published 2024-11-01“…The goal of this note is to describe the action of pseudo-differential operators on the space of square integrable functions which are harmonic outside a smooth closed hyper-surface of a compact Riemannian manifold.…”
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470
Effects of Adhesive Connection on Composite Action between FRP Bridge Deck and Steel Girder
Published 2017-01-01“…However, the understanding of composite action between FRP decks and steel girders is limited and needs to be systematically investigated. …”
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471
Examining Mammalian facial behavior using Facial Action Coding Systems (FACS) and combinatorics.
Published 2025-01-01“…Such approaches include Facial Action Coding Systems (FACS), where individuals are trained to identify discrete facial muscle movements that combine to create a facial configuration. …”
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472
Combining ability and gene action for resistance to Fusarium ear rot in tropical maize hybrids
Published 2025-01-01Subjects: Get full text
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Human sciences can increase technology acceptance in rehabilitation science: a call for action
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Buen Vivir or Sumak Kawsay. In Search of New Referential Frame for Public Action in Ecuador
Published 2014-05-01Subjects: Get full text
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477
Safety and Mode of Action of Diabetes Medications in comparison with 5-Aminolevulinic Acid (5-ALA)
Published 2019-01-01“…Thus, in this review, we evaluate the mechanisms of action and adverse effects of common medications used to treat type 2 diabetes mellitus as well as 5-ALA including its mechanism and possible use in diabetes management.…”
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478
Dynamic Response Analysis of Dowel-Slot Grouting Assembly Station under earthquake action
Published 2025-01-01“…The results indicate that the two stations have the same stress concentration position and the same weak point under different seismic actions, and both meet the aseismic requirements. …”
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Action Video Game Experience Related to Altered Large-Scale White Matter Networks
Published 2017-01-01“…With action video games (AVGs) becoming increasingly popular worldwide, the cognitive benefits of AVG experience have attracted continuous research attention over the past two decades. …”
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480
Soil Erosion Process Under the Combined Action of Water and Gravity on Red Soil Slope
Published 2024-12-01“…Through the method of artificial simulation of continuous rainfall in the field, the influence of gravel content on soil erosion process and its synergistic change rule under the combined action of water and gravity were discussed. [Results] (1) Gravel-free soil did not produce runoff under two rainfalls. …”
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