Efficacy of PARPi re-maintenance therapy for recurrent ovarian cancer by Yulin Wang, Yunjie Yang, Binghong Guo, Binghong Guo, Xiaoyan Li, Renakezi Tuersun, Ye Cao, Jundong Li, Jihong Liu, Su Li, Tao Liu, Yongwen Huang

“…This study aims to investigate the efficacy and associated factors of PARPi re-maintenance therapy in PSROC patients in China.MethodsIn this study, there were 201 patients with PSROC who had received maintenance therapy previously and achieved complete or partial response after platinum-based chemotherapy upon recurrence. …”
Get full text

Dietary supplementation with compound microecological preparations: effects on the production performance and gut microbiota of lactating female rabbits and their litters by Chengcheng Zhao, Youhao Li, Hui Wang, Ahamba Ifeanyi Solomon, Shuhui Wang, Xianggui Dong, Bing Song, Zhanjun Ren

“…Adding antibiotics to rabbit feed can achieve the effect of preventing and treating inflammation, which can also lead to the imbalance of the gut microbiota and residual antibiotics in agricultural products. …”
Get full text

Association between domain-specific physical activity and triglyceride‑glucose (TyG) index among US adults: Evidence from NHANES 2007–2018 by Kai Yao

“…Weighted multivariable linear regression showed that leisure-time MVPA (LT-MVPA), whether at any amount or achieving physical activity guidelines, was negatively associated with TyG index (β = -0.10, 95%CI: -0.13- -0.07, P < 0.001, and β = -0.13, 95%CI: -0.17- -0.10, P < 0.001, respectively). …”
Get full text

Research on time–frequency characteristics of electromagnetic signals from coal and rock blasting based on DBO-VMD filtering by Litao WANG, Liming QIU, Menghan WEI, Dazhao SONG, Rentao GOU, Lin LIU, Shiqiang ZHONG, Tianyi XIE

“…It provides enhanced smoothing and fidelity of pure signals and is more efficient at noise screening. The DBO-VMD achieves a signal-to-noise ratio about two times that of the EMD. …”
Get full text

Decentralized Management of Home Care Services for Seniors: Protocol for a Participatory Action Research by Virginie Savaria, Johanne Queenton, Annie Carrier

“…The specific objectives, in collaboration with local HCS stakeholders, are to (1) identify concrete and achievable strategies for decentralized management, and (2) describe factors (facilitators and obstacles) that could potentially influence their integration. …”
Get full text

Exploring the upper ocean characteristics of a bay using coastal and regional ocean community model by D. Jaishree, P.T. Ravichandran

“…BACKGROUND AND OBJECTIVES: The innovativeness of this study lies in achieving a comprehensive understanding of the seasonal variations and oceanic characteristics of the Bay of Bengal by addressing the complex interplay of large-scale ocean-atmosphere dynamics. …”
Get full text

The Effectiveness of Rapamycin Combined with Eltrombopag in Murine Models of Immune-Mediated Bone Marrow Failure by Shaoxue Ding, Xiaowei Liang, Tian Zhang, Rong Fu

“…However, it has not achieved a satisfactory effect in clinical application. …”
Get full text

Relationship Between ABO Blood Groups and Mental Disorders by Ajdacic-Gross V, Buadze A, Wagner EYN, Müller M, Seifritz E, Ranjbar S, Glaus J, Castelao E, Strippoli MPF, Vandeleur CL, Preisig M, von Känel R

“…Large databases are needed to achieve more detailed results related to specific disorders.Plain Language Summary: Prior research has shown an interesting link between the AB blood group and mental disorders. …”
Get full text

Enhancing deep learning methods for brain metastasis detection through cross-technique annotations on SPACE MRI by Tassilo Wald, Benjamin Hamm, Julius C. Holzschuh, Rami El Shafie, Andreas Kudak, Balint Kovacs, Irada Pflüger, Bastian von Nettelbladt, Constantin Ulrich, Michael Anton Baumgartner, Philipp Vollmuth, Jürgen Debus, Klaus H. Maier-Hein, Thomas Welzel

“…Conclusion HAQ improves DL methods without specialized imaging during application time. HAQ alone achieves about 40% of the performance improvements seen with SPACE images as input, allowing for fast and accurate, fully automated detection of small (< 1 cm) BMs. …”
Get full text

Protective factors, risk factors, and intervention strategies in the prevention and reduction of crime among adolescents and young adults aged 12-24 years: A scoping review protoco... by Rosanna Mary Rooney, Amber Hopkins, Jacob Peckover, Kael Coleman, Rebecca Sampson, Rosa Alati, Sharinaz Hassan, Christina M Pollard, Jaya A R Dantas, Roanna Lobo, Zakia Jeemi, Sharyn Burns, Robert Cunningham, Stephen Monterosso, Lynne Millar, Sender Dovchin, Rhonda Oliver, Ranila Bhoyroo, Getinet Ayano

“…Additionally, it will likely highlight significant trends in risk and protective factors, such as the dual role of academic achievement-both as a risk and protective factor-and the impact of family-based interventions. …”
Get full text

Health recommender systems to facilitate collaborative decision-making in chronic disease management: A scoping review by Antonia Barbaric, Kenneth Christofferson, Susanne M Benseler, Chitra Lalloo, Alex Mariakakis, Quynh Pham, Joost F Swart, Rae S M Yeung, Joseph A Cafazzo

“…From the thematic analysis, we conclude: (a) the main goal of HRSs is to induce behavior change, but limited research investigates their effectiveness in achieving this aim; (b) studies acknowledge that theories, models, frameworks, and/or guidelines help design HRSs to elicit specific behavior change, but they do not implement them; (c) connections between CDM and HRS purpose should be more explicit; and (d) HRSs can often offer other self-management services, such as progress tracking and chatbots. …”
Get full text

The Impact of Complete Revascularization in Symptomatic Severe Left Ventricular Dysfunction between Coronary Artery Bypass Graft and Percutaneous Coronary Intervention by Hsiu-Yu Fang, Yen-Nan Fang, Yin-Chia Chen, Jiunn-Jye Sheu, Wei-Chieh Lee

“…Therefore, an extensive revascularization, achieved by CABG or PCI, is associated with a lower HF hospitalization rate during the 3-yearfollow-up period in such populations.…”
Get full text

Nomogram based on the neutrophil-to-lymphocyte ratio and MR diffusion quantitative parameters for predicting Ki67 expression in hepatocellular carcinoma from a prospective study by Yu-chen Wei, Liang yun, Yan-ling Liang, Robert Grimm, Chongze Yang, Yuan-fang Tao, Sheng-chen Jiang, Jin-yuan Liao

“…Additionally, when used to predict the one-year recurrence risk, the combined model achieved moderate accuracy (AUC = 0.747), highlighting its potential utility in identifying patients at a higher risk of recurrence. …”
Get full text

Peningkatan Akurasi Mesin Penerjemah Bahasa Inggris - Indonesia dengan Memaksimalkan Kualitas dan Kuantitas Korpus Paralel by Herry Sujaini

“…In addition, better translation performance can be achieved with a smaller high-quality corpus using a quality filter method.The experimental results in the English-Indonesian SMT show that by using 60% of sentences whose translation quality is good, the quality of the translation can increase by 7.31%. …”
Get full text

Intratumoral pan-ErbB targeted CAR-T for head and neck squamous cell carcinoma: interim analysis of the T4 immunotherapy study by Fiona Reid, Sophie Papa, John Maher, Jean-Pierre Jeannon, James Spicer, Victoria Gibson, Selvam Thavaraj, Michael Metoudi, Christopher Fisher, Nicholas Beckley-Hoelscher, Andrew Hope, Maria Elstad, Antonella Adami, Richard Beatson, Molly Sarah George, Daniela Achkova, Evangelia Williams, Sefina Arif, Abdel Douri, Marc Delord, Mike Lyne, Dharshene Shivapatham, Sakina Gooljar, Arindam Mitra, Linda Gomm, Cienne Morton, Rhonda Henley-Smith, Alice Santambrogio, Cynthia Andoniadou, Sarah Allen, Gary J R Cook, Ana C Parente-Pereira, David M Davies, Farzin Farzaneh, Anna Schurich, Teresa Guerrero-Urbano

“…Subsequent treatment with pembrolizumab and T-VEC oncolytic virus achieved a rapid complete clinical response in one subject, which was durable for over 3 years. …”
Get full text

Eu:CROPIS AIV Program: Challenges and Solutions for a Spin-Stabilized Satellite Containing Biology by Toni Delovski, Catherin Düvel, Fabian Greif, Ansgar Heidecker, Sebastian Kottmeier, Olaf Mierheim, Falk Nohka, Fabian Orlowski-Feldhusen

“…Its primary payload focuses on the research of closed-loop biological, regenerative life support systems, in a simulated gravitational environment of the Moon and Mars over months at a time. This is achieved by rotation of the satellite around its central body axis, using only magnetic torquers as actuators. …”
Get full text

Return to Play Assessment After Lateral Ankle Sprains – German Male Elite Youth Football (Soccer) Academy Baseline Data by Zacharias Flore, Götz Welsch, Hendrik Bloch

“… # Results Male elite youth football players achieved better results in the dynamic performance tests (SHT, F-8, and MAT) compared to reference values of the cohorts previously described in the literature: YBT-LQ total score (cm) dominant (dom) 99.3±8.3, non-dominant (ND) 99.5±10.4; HRT (average number) dom. 27.1±5.4, ND 25.2±5.1); SLDJ height (cm) dom 15±5, ND 15±5 and contact time (sec) dom 0.29±0.08, ND 0.29±0.07, Reactive Strength Index (RSI) dom 0.52±0.12, ND 0.50±0.13); SHT (sec) dom 7.12±0.73, ND 7.39±0.93; F-8 (sec) dom 10.52±1.02, ND 10.37±1.04; and MAT (sec) 5.82±0.22. …”
Get full text

¿La combinación dolutegravir y rifampicina en los pacientes no incluidos en los ensayos clínicos es también eficaz y segura en el binomio VIH-infección micobacteriana? Casos de la... by Sara Fontserè Recuenco, Rafael Luque-Márquez

“…From which completed follow-up, 91.6% achieved mycobacterial curation (11 of 12) and 92.9% viral load suppression (13 of 14). …”
Get full text

Bibliometric analysis and review of food waste management via sustainable approaches by U. Danya, M. Kamaraj, P. Suresh Babu, J. Aravind

“…By highlighting the role of these biorefineries in achieving sustainable development goals, the review emphasizes the need for continued research, technological innovation, and supportive policy frameworks. …”
Get full text

HIV viral load suppression rates among adults and children living with HIV in the North West Region of Cameroon: A call for action! by Gladys Fosah E Tayong, Melissa Sander, Comfort Vuchas, Moses Samje, Vera Kum, Pascal Enokbonong, Eugene Yeika, Ndanga Bekombo, Paul Nyibio, Vanessa B Ngwani, Justin Ndié, Njamnshi Wepnyu Yembe, Gloria Ashuntangtang

“…Action is needed to tackle all known factors contributing to high viral non-suppression in children living with HIV and to help achieve 95% viral suppression rate in CLHIV in the North West region of Cameron.…”
Get full text