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28781
A Comparative Study between Postoperative Analgesia of Fascia Iliaca Compartment Block and Anterior Quadratus Lumborum Block in Proximal Femur Fracture
Published 2022-01-01“…The time required to achieve first rescue analgesia was much less in the FICB group (8.5 ± 2.2) compared to the QLB group (14.1 ± 4.5), P value (<0.001∗), and they took much longer to ambulate (22.3 ± 4.8) when compared to the QLB group (20.1 ± 4.6), P value (0.011∗). …”
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28782
Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning
Published 2025-01-01“…The accuracy of the Lasso regression model was 0.864, XGBoost achieved 0.903, and RandomForest reached 0.961. Resampling internal validation revealed that RandomForest had the highest recall rate (AUC = 0.892). …”
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28783
Application of organoids in drug screening of gynecological malignant tumors
Published 2024-11-01“…Recent studies have shown that the same type of tumor exhibits significant biological characteristics and drug response heterogeneity among different individuals, which is a key factor contributing to the varied clinical outcomes when using the same drug treatment for the same type of gynecologic malignant tumor. To achieve individualized and precise treatment for gynecologic malignant tumors, there is an urgent need to develop in vitro models that closely resemble human tumors for clinical research. …”
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28784
Implementing and evaluating the comprehensive integration of physical activity into a major health system: study design and protocol
Published 2025-01-01“…A mixed-methods approach will explore factors related to EIMG adoption, achieving optimal implementation and reach, and patient enrolment in the PA programmes. …”
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28785
Glaucoma detection and staging from visual field images using machine learning techniques.
Published 2025-01-01“…<h4>Results</h4>The DL model, ResNet18 trained from balanced, pre-augmented PD images, achieved high accuracy in classifying the groups with an overall F1-score: 96.8%, precision: 97.0%, recall: 96.9%, and specificity: 99.0%. …”
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28786
Synergistic effect of mulch and nitrogen management on growth and essential oil yield of Salvia sclarea L.
Published 2024-12-01“…Abstract Balanced plant nutrition and optimal micro-climate are critical for achieving higher production sustainably. Substituting mineral fertilizers with organic amendments under water-conserving strategies like mulch can enhance the quality and yield and improve soil health. …”
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28787
Utilization of donor CLL-1 CAR-T cells for the treatment of relapsed of acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation
Published 2025-01-01“…All patients demonstrated a reduction in tumor burden, while 7 patients (58.33%) achieved MRD-CR and 2 patients (16.67%) reached MRD+CR. …”
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28788
Matching-Adjusted Indirect Comparison of the Efficacy and Safety of Erdafitinib vs Enfortumab Vedotin in Patients with Locally Advanced Metastatic Urothelial Carcinoma
Published 2024-08-01“…**Conclusion:** The MAIC indicates comparable efficacy of erdafitinib vs EV for overall survival and progression-free survival, with erdafitinib showing a higher probability of achieving deep responses. While erdafitinib is associated with slightly more adverse events compared with EV, these events seem to be less severe.…”
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28789
Comparing physiological and psychological effects of virtual reality vs. traditional high-intensity interval training in healthy individuals: results from a preliminary pilot rando...
Published 2025-01-01“…Results Statistical analysis showed no significant difference in heart rate parameters between the VR and non-VR groups, indicating that both interventions achieved comparable exercise intensity and meeting the recommended levels for health benefits. …”
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28790
Das Menschliche in der Musik . August Halms prozessuale Metaphorik im Brennpunkt analysetheoretischer Fragestellungen
Published 2021-12-01“…It is worth examining some of the “energetic” conceptualizations that are typical of Halm’s understanding of music, both to see how they function cognitively and what they can achieve. This examination also occurs with the aim of making their potential available for serious present-day music analysis.…”
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28791
TC2N maintains stem cell-like characteristics to accelerate lung carcinogenesis by blockade of dual specificity protein phosphatase 3
Published 2025-01-01“…In previous studies, we have uncovered the oncogenic role and mechanisms of TC2N in lung cancer: TC2N achieves this by inhibiting the p53 signaling pathway and activating the NF-kappaB signaling pathway. …”
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28792
Cost-benefit analysis of VKA versus NOAC treatment in German patients with atrial fibrillation utilizing patient self-testing
Published 2019-08-01“…To capture the interactions between multiple inputs, we also provided a probabilistic sensitivity analysis (PSA). **Results:** When achieving an average time in therapeutic range (TTR) of 78%, implementing PST in VKA patients reduces cost per patient compared to NOAC treatment between €603.38 [USD 681.52] (edoxaban) and €762.64 [USD 861.40] (rivaroxaban) during the 1-year observation period. …”
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28793
Nanopore-based random genomic sampling for intraoperative molecular diagnosis
Published 2025-01-01“…Furthermore, we validated iSCORED’s real-time applicability in 15 diagnostically challenging primary brain tumors, achieving 100% concordance in detecting aberrant CNV detection, including diagnostic chromosomal gains/losses and oncogene amplifications (10/10). …”
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28794
Investigating the Feasibility of Behavioral Nudges to Reduce the Phenomenon of Escape from Responsibility in Public Sector
Published 2024-06-01“…Escape from responsibility among managers is a significant threat to the effectiveness of the organization and prevents progress towards achieving strategic goals. By understanding the underlying psychological underpinnings of this issue and applying the principles of behavioral science, organizations can effectively reduce this issue and foster a culture of responsible management. …”
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28795
Deficit irrigation enhances yield and water productivity of apples by inhibiting excessive vegetative growth and improving photosynthetic performance
Published 2025-02-01“…The I-W15 %, II-W15 %, II-W30 %, and IV-W15 % treatments synergistically improve both apple yield and WP, suggesting that these DDI treatments could be recommended for growers aiming to achieve sustainable apple production.…”
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28796
The epidemiology of malaria in four districts in southern Mozambique receiving indoor residual spray as part of a cross-border initiative
Published 2025-01-01“…Implementation of IRS was also monitored to ensure optimal spray coverage was achieved. Methods The study was a cross-sectional survey conducted in 6 sentinel sites in each of the four afore-mentioned districts, focusing on children 6 months to < 15 years from selected households. …”
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28797
The spiritual way to desistance?
Published 2024-11-01“…., their age and type of sentence, the participants already had such a low risk of recidivism as to make further reduction difficult to achieve. Under åren 2001-2019 bedrev Kriminalvården i Sverige en kristen retreatverksamhet på anstalten Kumla, dit långtidsdömda fångar kunde söka sig. …”
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28798
The implementation of genome sequencing in rare genetic diseases diagnosis: a pilot study from the Hong Kong genome projectResearch in context
Published 2025-02-01“…Findings: A total of 1264 individuals from 520 families with a broad spectrum of RDs were recruited, with 94% of probands being Chinese. srGS was performed for all individuals and lrGS was performed in 21 individuals. The use of srGS achieved a molecular diagnosis in 24% (125/520) of probands, and an additional 4% (21/520) with the assistance from lrGS. …”
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28799
First results of the EuroHeart program
Published 2024-12-01“…In Sweden, the vessel was opened in 90.9% of the patients within 12 hours of the onset of the complaint, in Hungary this was only achieved in 46.4% of the treatments. At the time of discharge from the hospital, among the drugs important in secondary prevention, statin use was the most common (92.1%). …”
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28800
A basis water quality monitoring plan for rehabilitation and protection
Published 2022-04-01“…From this, a scientific basis can be drawn on how the river can be rehabilitated and protected and serve as guide for policymakers and water managers on implementing strategies to achieve sustainable water resources.…”
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