Breakthrough Psoriasis in Patients Receiving Biologicals by Damsin T, Absil G, Libon F, Tassoudji N, Nikkels AF

“…However, on occasion, patients on biological therapy with stabilized disease or complete remission report episodes of sudden breakthrough psoriasis.Aim: To study prospectively in a monocentric tertiary setting, the clinical characteristics of patients presenting a sudden breakthrough psoriasis although completely stabilized (PASI 90– 100) under biological therapy.Materials and Methods: Psoriasis patients treated by biological therapies achieving PASI 90– 100 and with stabilized disease for at least 6 months were invited to enter the follow-up study for 5 years. …”
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The mcpC mutant of Salmonella enteritidis exhibits attenuation and confers both immunogenicity and protective efficacy in mice by Lu Zhang, Li Chen, Xuqiang Zhang, Yang Li, Qingfeng Zheng, Yun Li, Ning Li, Qiumei Shi, Yanying Zhang, Tonglei Wu

“…Immunization with ΔmcpC induced the production of specific IgG and SIgA antibodies, enhanced lymphocyte proliferation, upregulated cytokine expression, and achieved a 100% survival rate in immunized mice. These findings indicate that ΔmcpC provides effective immune protection in mice.ConclusionThis study demonstrates that deletion of the mcpC gene attenuates the virulence of SE. …”
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A lightweight wheat ear counting model in UAV images based on improved YOLOv8 by Ruofan Li, Xiaohua Sun, Kun Yang, Zhenxue He, Zhenxue He, Xinxin Wang, Xinxin Wang, Chao Wang, Chao Wang, Bin Wang, Fushun Wang, Fushun Wang, Hongquan Liu, Hongquan Liu

“…Experimental results demonstrate that the improved PSDS-YOLOv8 model achieves Mean Average Precision(mAP) 50 and mAP50:95 scores of 96.5% and 55.2%, which increases by 2.8% and 4.4%, while the number of parameters is reduced by 40.6% in comparison with the baseline YOLOv8 model. …”
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Dental profiling in the archaeological sample of the Illyrian population in Southern Dalmatia, Croatia by Marina Marić, Jelena Dumančić, Marin Vodanović, Igor Borzić, Dinko Radić, Davorka Radovčić, Hrvoje Brkić

“…Aims: The research aims to gain insights into the diet, health, socio-economic status, and demography of the Late Iron Age inhabitants of Illyrian origin who lived on the Croatian island of Korčula. This will be achieved by analyzing the remains of teeth and jaw bones found in the Kopila necropolis. …”
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HEDDI-Net: heterogeneous network embedding for drug-disease association prediction and drug repurposing, with application to Alzheimer’s disease by Yin-Yuan Su, Hsuan-Cheng Huang, Yu-Ting Lin, Yi-Fang Chuang, Sheh-Yi Sheu, Chen-Ching Lin

“…Results In experiments, HEDDI-Net achieves areas under the receiver operating characteristic curve of over 0.98, outperforming state-of-the-art methods. …”
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Microplastic analysis in soils: A comparative assessment by Stoyana Peneva, Quynh Nhu Phan Le, Davi R. Munhoz, Olivia Wrigley, Flora Wille, Heidi Doose, Crispin Halsall, Paula Harkes, Michael Sander, Melanie Braun, Wulf Amelung

“…For the latter, reliable quantification was achieved only using Soxhlet extraction combined with 1H NMR spectroscopic quantification. …”
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Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial by Graham McIlroy, Charlotte Gaskell, Aimee Jackson, Emily Yafai, Rachel Tasker, Catherine Thomas, Sonia Fox, Rebecca Boucher, Fitsum Ghebretinsea, Claire Harrison, Adam J. Mead, Mary Frances McMullin

“…It has shown activity in MF and is well-tolerated, but combination with other therapies is likely needed to achieve clonal remission. Combining a JAK2 inhibitor with an interferon may be synergistic, as haematopoietic cells are activated from quiescence (a typical kinase resistance mechanism) rendering them more sensitive to inhibition. …”
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Several factors that predict the outcome of large B‐cell lymphoma patients who relapse/progress after chimeric antigen receptor (CAR) T‐cell therapy can be identified before cell a... by Alice Sýkorová, František Folber, Kamila Polgárová, Heidi Móciková, Juraj Ďuraš, Kateřina Steinerová, Aleš Obr, Adriana Heindorfer, Miriam Ladická, Ľubica Lukáčová, Erika Čellárová, Ivana Plameňová, David Belada, Andrea Janíková, Marek Trněný, Tereza Jančárková, Vít Procházka, Andrej Vranovský, Margaréta Králiková, Jan Vydra, Lukáš Smolej, Ľuboš Drgoňa, Martin Sedmina, Eva Čermáková, Robert Pytlík

“…Conclusion Our findings allow better stratification of CAR‐Tx candidates and stress the need for a proactive approach (earlier restaging, intervention after partial remission achievement).…”
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Detection Methods for Asparagine and Glutamine Contents in Fruits and Vegetables and Recommendations for Dietary Intake of Fruits and Vegetables in Patients with Urea Cycle Disorde... by YE Xinyu, LI Ziying, TANG Shujun, SUN Liping, ZHAO Yunxia, XIAO Weimin, GU Yaping, KUANG Huiying, CHEN Xin, YANG Guowu, HUANG Yali

“…The mass spectrometer was equipped with an electrospray ionization source and operated in the positive ion mode with multiple reaction monitoring (MRM), and quantification was achieved using stable isotope-labeled internal standards. …”
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Stimulating Financial-Fiscal Instruments of Supporting Development of Renewable Energy Sources: Bibliometric Analysis by Alla Moroz, Serhiy Lyeonov

“…By leveraging these insights, policymakers and researchers can enhance the design and implementation of fiscal tools to achieve global climate and sustainability goals.…”
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Variative Components of the University Course of Mathematical Analysis: The Experience of Introduction into the Practice of Teaching by S. I. Кalinin, L. V. Pankratova

“…The results of the formation of professional competencies of future graduates obtained during pedagogical measurements (questionnaires, surveys of students, observation of their educational and research achievements) confirmed the effectiveness of using the designed variable components of the discipline “Mathematical Analysis” in the learning process.Practical significance. …”
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A new hybrid distance and similarity based scenario reduction approach for stochastic economic operation of microgrid by Gaurav Gangil, Amit Saraswat, Sunil Kumar Goyal

“…The proposed HDS method is found to be capable in achieving the lowest OSDI value of 5.68 at 98 % scenario reduction while compared to other competing methods i.e. 12.95 by SBR, 14.76 by FFS, and 16.32 by SIMCOR for the real-life microgrid problem. …”
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Fruit Detection and Yield Mass Estimation from a UAV Based RGB Dense Cloud for an Apple Orchard by Marius Hobart, Michael Pflanz, Nikos Tsoulias, Cornelia Weltzien, Mia Kopetzky, Michael Schirrmann

“…Overall, coefficients of determination of 0.56 (for the 7.5 m altitude flight) and 0.76 (for the 10 m flights) were achieved. Therefore, we conclude that mapping at an altitude of 10 m performs better than 7.5 m, in the context of low-altitude UAV flights for the estimation of ripe apple parameters directly from 3D RGB dense point clouds.…”
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Exploring the allometry between ear saturated water accumulation and dry mass for diagnosing winter wheat water status during the reproductive growth by Tingxuan Zhuang, Ben Zhao, Syed Tahir Ata-Ul-Karim, Gilles Lemaire, Xiaojun Liu, Yongchao Tian, Yan Zhu, Weixing Cao, Qiang Cao

“…Accurate diagnosis of water status during the reproductive growth phase is imperative for achieving precision water management in winter wheat cultivation. …”
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Structured Polyvinyl Alcohol/Zeolite/Carbon Composites Prepared Using Supercritical Fluid Extraction Techniques as Adsorbent for Bioethanol Dehydration by Joddy Arya Laksmono, Mahmud Sudibandriyo, Asep Handaya Saputra, Agus Haryono

“…Further, by using approximately 4.5 gram adsorbents composite in 30 ml of water-ethanol mixtures, high concentration of bioethanol (>99%) can be achieved at various temperatures from 22°C to 40°C and bioethanol initial concentration from 88% to 96%. …”
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Fusarium oxysporum assisted green synthesis of small-sized silver nanoparticles for high antibacterial, and photocatalytic decolorization performances by Reyad M. El-Sharkawy, Inas A. Ahmed, Taghrid G. Kharboush

“…Results The successful biofabrication of smaller-sized SNPs with an average particle size of ~ 5 nm was achieved upon the bioprocess optimization. The developed SNPs exhibited significant antibacterial activity against multidrug-resistant bacterial pathogens in a concentration- and time-dependent manner. …”
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Eco-anthropologie et primatologie pour la conservation de la biodiversité : un projet collaboratif dans le Parc National de Moukalaba-Doudou, Gabon by Naoki Matsuura, Yuji Takenoshita, Juichi Yamagiwa

“…Their interdisciplinary achievements may provide clues to establish a system of biodiversity conservation along with concerns for local welfare. …”
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Dietary ferulic acid improves growth performance of broilers via enhanced intestinal antioxidant capacity and barrier function by Yaodong Hu, Shi Tang, Wei Zhao, Silu Wang, Caiyun Sun, Binlong Chen, Yuxing Zhu

“…The current findings provided evidence that the adoption of FA can be a nutrition intervention measure to achieve high-efficient broiler production for poultry farmers.…”
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LcProt: Proteomics‐based identification of plasma biomarkers for lung cancer multievent, a multicentre study by Hengrui Liang, Runchen Wang, Ran Cheng, Zhiming Ye, Na Zhao, Xiaohong Zhao, Ying Huang, Zhanpeng Jiang, Wangzhong Li, Jianqi Zheng, Hongsheng Deng, Yu Jiang, Yuechun Lin, Yun Yan, Lei Song, Jie Li, Xin Xu, Wenhua Liang, Jun Liu, Jianxing He

“…For task #2, nine proteins panel achieved an AUC of .88 (.80‒.96), integration model showed an increase diagnostic accuracy with AUC of .90 (.85‒.97). …”
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Characterization of Local Nano-Heat Transfer Fluids for Solar Thermal Collection by Kawira Millien

“…Extraction of organic oils from plants can be locally achieved. The purpose of this study was to investigate the effect of use of copper nanoparticles in some base local heat transfer fluids (HTFs). …”
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