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27981
Integrated analysis of ATAC-seq and RNA-seq reveals ADSCP2 regulates oxidative phosphorylation pathway in hypertrophic scar fibroblasts
Published 2025-01-01“…Consequently, this study sought to elucidate the potential mechanism associated with ADSCP2 by examining genome-wide transcriptional alterations and changes in chromatin accessibility in fibroblasts. This was achieved through the integrated analysis of assay for transposase accessible chromatin using sequencing (ATAC-seq) and RNA sequencing (RNA-seq). …”
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27982
Environmental and economic drivers of subjective well-being: evaluating the effects of pollution, income growth, and income inequality in Pakistan
Published 2024-12-01“…These results highlight the need for Pakistan to prioritize sustainable environmental practices to achieve a clean and healthy environment. Furthermore, the country should promote economic inclusion and strive to create decent employment opportunities, ultimately leading to higher incomes and improved well-being for its citizens.…”
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27983
Obesity prevalence among healthcare professionals in England: a cross-sectional study using the Health Survey for England
Published 2017-12-01“…Further research is required to better understand the reasons for high obesity prevalence among healthcare professionals in England to inform interventions to support individuals to achieve and maintain a healthy weight.…”
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27984
System Design and Optimisation Study on a Novel CCHP System Integrated with a Hybrid Energy Storage System and an ORC
Published 2020-01-01“…For achieving higher energy transferring efficiency from the resources to the load, the Combined Cooling, Heating, and Power (CCHP) systems have been widely researched and applied as an efficient approach. …”
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27985
Forensic Support of Pre-Trial Investigative and Inquiry Agencies’ Activities on Combating Crime
Published 2021-09-01“…The author has studied the issues of current state and tendencies of criminalistics development, existing problematic issues and expediency of changing the scientific paradigm of criminalistics, application of innovations, introduction of modern achievements in the field of telecommunication and digital technologies, communication lines, Internet and the ways of their practical usage and further improvement. …”
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27986
Drivers of success in global health outcomes: A content analysis of Exemplar studies.
Published 2024-01-01“…Top drivers of success were defined as those critical or catalytic in achieving the intended outcome. Eight key drivers were identified: (1) efficient data collection and use for decision-making, (2) strong political commitment and health leadership, (3) effective stakeholder coordination, (4) a local, connected, and capacitated workforce, (5) intentional women's empowerment and engagement, (6) effective adoption and implementation of national policies, (7) effective and sustainable financing, and (8) equitable, efficient outreach and targeting. …”
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27987
Multisectoral actions in primary health care: A realist synthesis of scoping review.
Published 2023-01-01“…<h4>Background</h4>Multisectoral actions (MSAs) on health are key to implementation of primary health care (PHC) and achieving the targets of the Sustainable Development Goal 3. …”
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27988
Interaction of the National Police of Ukraine and civil society institutions: concept and legal framework
Published 2023-09-01“…Based on the results of a multidisciplinary generalisation of the scholars’ achievements in the field of Administrative Law, it has been determined that in a broad sense, interaction between the National Police of Ukraine and civil society institutions should be understood as their joint coordinated activities regulated and carried out in accordance with the requirements of current legislation, which may take various forms and is embodied in a large number of measures whose overall purpose is to ensure the formation of a secure environment in the State. …”
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27989
Transitioning from wet lab to artificial intelligence: a systematic review of AI predictors in CRISPR
Published 2025-02-01“…Following the success of artificial intelligence (AI) in various fields, researchers are now leveraging AI algorithms to catalyze and optimize the multi-step process of CRISPR-Cas9 system. To achieve this goal AI-driven applications are being integrated into each step, but existing AI predictors have limited performance and many steps still rely on expensive and time-consuming wet-lab experiments. …”
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27990
Effectiveness of Aedes-borne infectious disease control in Latin America and the Caribbean region: A scoping review.
Published 2022-01-01“…Biological control measures, environmental management, and health education campaigns on community participation achieved more sustainable results than an intervention where only a chemical control measure was used. …”
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27991
Enhancing the filtration performance of common substrates used in the Covid-19 respiratory protection equipment with nanofiber coatings
Published 2025-01-01“…The initial filtration efficiency, pressure drop, and quality factor of the prepared media were then measured.The results clearly indicated that the application of PAN and PAN/CuBTC nanofiber coatings significantly enhances the filtration efficiency of all examined substrate layers, achieving efficiencies exceeding 90 % and 95 % at the most penetrating particle size (MPPS, 300 nm), respectively.The assessment of the quality factor revealed that the highest quality factor values before and after coating with PAN and PAN/CuBTC nanofibers corresponded to the SSMMS substrates, with values of 0.023, 0.072, and 0.094 Pa⁻1, while the lowest quality factor values were associated with Tetron, which had values of 0.002, 0.016, and 0.021 Pa⁻1, respectively.The comparison of various substrates revealed that the SSMMS fabric exhibited the highest quality factor after coverage with nanofibers, while the Tetron fabric demonstrated the lowest quality factor.Based on the quality criteria, the SSMMS fabric was the best substrate for nanofiber coatings, followed by melt-blown, spun bond, and activated carbon fabrics, whereas the Tetron fabric was not recommended for this application due to a high respiratory pressure drop.…”
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27992
Enhanced photocatalytic degradation of Rhodamine B using polyaniline-coated XTiO3(X = Co, Ni) nanocomposites
Published 2025-01-01“…The 1%wt PANI@NiTiO3 achieved an impressive 94% degradation of RhB under visible light after 180 min, while 1wt.% PANI@CoTiO3 reached 87% degradation under UV light in the same duration. …”
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27993
Modelling the epidemiological and economic impact of digital adherence technologies with differentiated care for tuberculosis treatment in Ethiopia
Published 2024-12-01“…The maximum possible epidemiological impact a theoretical DAT intervention could achieve over the same timescale would be a 3% (95% UI 1.4%; 5.5%) reduction in incident TB and an 8.2% (95% UI 4.4%; 12.8%) reduction in TB deaths.Interpretation DAT interventions, while showing limited epidemiological impact, could substantially reduce TB treatment costs for both patients and the healthcare provider.…”
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27994
A comparative analysis of alpha olefin sulfonate and dodecyl sulfate in aphronic fluid containing xanthan gum in a wide range of temperatures
Published 2025-01-01“…Moreover, the best stability was achieved at 1.5 times the critical micelle concentration (CMC). …”
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27995
Arbitrary Fixed-Time Sliding Mode Control for Buck Converter With Matched and Mismatched Disturbances Based on Fixed-Time Observer
Published 2025-01-01“…The FxDO-FxSMC method 1) tackles an arbitrary fixed time sliding surface for the buck converter with mismatched disturbance, a feature not achievable with the current finite/fixed time sliding mode control; 2) allows the user to adjust the convergence time of the proposed method, regardless of the initial conditions; and 3) concurrently mitigates chattering issues. …”
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27996
Two-dimensional semantic morphological feature extraction and atlas construction of maize ear leaves
Published 2025-02-01“…Inbred line identification of 2D leaf shape in maize was achieved using the atlas. The results of maize leaf inbred line identification can determine the probability that the corresponding true inbred line ranked within the top 10 of the predicted results is 0.706, within the top 20 is 0.810, and within the top 45 is 0.900. …”
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27997
O efeito da complexidade econômica e relatedness sobre o crescimento das microrregiões brasileiras
Published 2024-12-01“…Em terceiro lugar, um achado importante é que existem efeitos desiguais da complexidade econômica sobre o crescimento econômico quando examinadas separadamente as grandes regiões no Brasil, principalmente em relação ao PIB per capita. …”
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27998
A Systematic Literature Review and Indirect Treatment Comparison of Efficacy of Repository Corticotropin Injection versus Synthetic Adrenocorticotropic Hormone for Infantile Spasms
Published 2021-01-01“…In the indirect treatment comparison of six eligible clinical trial studies, the odds of achieving efficacy outcomes were five to eight times greater with RCI than with tetracosactide and 14 to 16 times greater than CCMC. …”
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27999
Single, double, and triple-hit strategies to establish a long-term premature rabbit model of bronchopulmonary dysplasia
Published 2025-01-01“…Enhanced BPD-like phenotypes can be further achieved by continued exposure to moderate hyperoxia (70% O2) and the intratracheal administration of LPS.…”
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28000
Regulation of static and dynamic balance in healthy young adults: interactions between stance width and visual conditions
Published 2025-01-01“…We recommend using a self-selected stance width to optimize static balance and a 30 cm stance width to achieve maximum limits of stability during postural assessments.…”
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