Assessing bnAb potency in the context of HIV-1 envelope conformational plasticity. by Caio Foulkes, Nikolas Friedrich, Branislav Ivan, Emanuel Stiegeler, Carsten Magnus, Daniel Schmidt, Umut Karakus, Jacqueline Weber, Huldrych F Günthard, Chloé Pasin, Peter Rusert, Alexandra Trkola

“…Importantly, for a subset of CD4bs bnAbs, and the interface bnAb PGT151, particularly low potency variation was noted, suggesting that Env conformational tolerance can be achieved but is not the rule. In summary, SENSE-19 screens revealed distinct tolerance levels to Env conformational intermediates between bnAbs that provide mechanistic insights in their function and broaden current neutralization breadth assessments.…”
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Liderança, estilos pessoais, estratégias e desempenho de micro e pequenos empresários do setor industrial de Fortaleza by Francisco Rogério de Morais Silva

“…As análises dos dados coletados mostraram que, a exemplo do que foi comprovado em estudos anteriores, determinadas características pessoais são mais associadas ao bom desempenho empresarial e tal associação é reforçada por estratégias relevantes para esse tipo de empresário. Além de comprovar achados de estudos anteriores sobre essas relações, o estudo atual revelou que é possível identificar traços de caráter que, somados ou identificados com características pessoais e estratégias psicológicas ou empresariais, melhoram o desempenho empresarial. …”
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Effect of Mining Thickness on Overburden Movement and Underground Pressure Characteristics for Extrathick Coal Seam by Sublevel Caving with High Bottom Cutting Height by Yongkang Yang, Yanrong Ma, Chunxu Ji, Tianhe Kang, Xingyun Guo

“…Some conclusions can be drawn as follows: (i) under the “beam-hinged cantilever beam rocks” structure theory, the rock pillar thickness which needs to be controlled increases linearly as a function of mining thickness is achieved, and the reason of increased of support resistance in full-mechanized caving mining in extremely thick seams is explained in the theory; (ii) based on the results of the theoretical analysis and the lab simulation tests, the law of the abutment pressure peak is inverse to the full-seam mining thickness, and the distance between abutment peak and working face is proportional to the full-seam mining thickness, that is to say that the damage range of overlying strata increased; (iii) there are three working states of loading support in extrathick coal seams, such as normal circumstance, lower main roof pressure, and higher main roof pressure, meanwhile these states keep changing; (iv) under the guarantee of stope safety conditions, due to lower support strength, it will benefit the special thick seam top-coal caving under normal circumstance; (v) increasing the supporting strength can balance the impact loading under the lower main roof pressure, guaranteeing valid support for roof strata; (vi) by releasing high pressure, due to lower production, lower recovery rate of coal and other measures guarantee the stability of the stope support in the case of the higher main roof pressure.…”
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Percutaneous microwave ablation, perfusion, and reconstruction combined with a synthetic bone substitute in symptomatic bone cysts: a minimum of 26 months follow-up by Wenhan Huang, Yuan Yan, Chongquan Huang, Hongyi Liao, Jinpeng Lin, Yu Zhang

“…Satisfactory cyst healing was achieved in 13 cases according to radiological parameters. …”
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Cultural humility strategies for recruitment and retention of minoritised participants: a scoping review protocol by Mireille Chehade, Kellie McLean, Samar Mohsen Ashmawi, Moroni Fernandez Cajavilca, Baomi T Phung, Maya N Clark-Cutaia, Brynne Campbell Rice

“…A third reviewer will be recruited to resolve discrepancies, if any. Records achieving consensus will have their full texts screened against the eligibility criteria and included in the final pool. …”
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Design of an Incremental Music Teaching and Assisted Therapy System Based on Artificial Intelligence Attention Mechanism by Dapeng Li, Xiaoguang Liu

“…This study designs artificial intelligence models from the perspectives of attention mechanism, contextual information guidance, and distant dependencies combined with incremental music teaching for the segmentation of MS (multiple sclerosis) lesions and achieves the automatic and accurate segmentation of MS lesions through the multidimensional analysis of multimodal magnetic resonance imaging data, which provides a basis for physicians to quantitatively analyze MS lesions, thus assisting them in the diagnosis and treatment of MS. …”
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Improved cattle farm classification: leveraging machine learning and linked national datasets by Guy-Alain Schnidrig, Guy-Alain Schnidrig, Rahel Struchen, Sara Schärrer, Dagmar Heim, Daniela Hadorn, Gertraud Schüpbach-Regula, Giulia Paternoster

“…Among these models, the Random Forest model demonstrated the highest level of performance, achieving an accuracy of 0.914 (95% CI: 0.890, 0.938) and an F1-Score of 0.879 (95% CI: 0.841, 0.913). …”
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The Therapeutic Effect of Nordic Walking on Freezing of Gait in Parkinson’s Disease: A Pilot Study by Agata Wróblewska, Agata Gajos, Urszula Smyczyńska, Andrzej Bogucki

“…The present study showed that NW training had a beneficial effect on FOG in PD and that the achieved improvement is long-lasting. Future research should clarify whether the observed improvement limited to FoG triggered by only some circumstances reflects different pathomechanisms of FoG subtypes.…”
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Distinct Murine Pancreatic Transcriptomic Signatures during Chronic Pancreatitis Recovery by Yinjie Zhang, Baibing Yang, Joy M. Davis, Madeline M. Drake, Mamoun Younes, Qiang Shen, Zhongming Zhao, Yanna Cao, Tien C. Ko

“…To explore how pancreatic recovery is achieved at the molecular level, we used RNA-sequencing (seq) and profiled transcriptomes during CP transition to recovery. …”
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Incidence, Risk Factors, and Modified Risk Assessment Model of Venous Thromboembolism in Non‐Hodgkin Lymphoma Patients by Wen Li, Rui Liu, Ying Shen, GongZhizi Gao, Rui Yang, Yiwen Wang, Ruoyu Yang, Zujie Lin, Ruijun Dong, Wanhong Zhao, Aili He, Ju Bai

“…Sequential testing of TM and TAT achieved a sensitivity of 66.7%, specificity of 100%, positive predictive value (PPV) of 100%, and negative predictive value (NPV) of 96.7%. …”
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A Cloud-Based Optimized Ensemble Model for Risk Prediction of Diabetic Progression—An Azure Machine Learning Perspective by V. K. Daliya, T. K. Ramesh

“…The experiment is performed and implemented in Microsoft’s Azure cloud, using Azure Machine Learning service, that leverages the advantages of cloud computing with respect to scalability, security and its potential integration possibilities into IoT-based smart healthcare systems.This aspect highlights its versatility and impact with respect to remote monitoring of patients as well. The ensemble achieves an 83.2% Area Under the Curve (AUC) of Receiver Operating Characteristics (ROC) score, indicating good classification efficiency. …”
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Spatio-temporal changes of water quality variables in a highly disturbed river by Z. Abdollahi, A. Kavian, S.H.R. Sadeghi

“…Hence, the current study aimed to assess spatial and temporal variations of pollutant in Zanjanrud River in different stations from headstream to tail of the river. To achieve this goal, semi-monthly samples were collected from October 2015 to Jun 2016 at 5 stations along the river. …”
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Effectiveness of a personal health coaching intervention (diabetescoach) in patients with type 2 diabetes: protocol for an open-label, pragmatic randomised controlled trial by Oliver Faude, Fiona Streckmann, Lukas Zahner, Markus Gerber, Vivien Hohberg, Jan-Niklas Kreppke, Jan Kohl, Eleonora Seelig, Daniel König

“…An appropriate lifestyle intervention can address this problem.Methods and analysis This study is based on the need to develop an intervention that helps patients to establish behavioural changes in order to achieve glycaemic control. The intervention will be evaluated in a monocentric, open-label, pragmatic, two-arm randomised controlled trial with a sample ratio of 1:1 and a parallel design. …”
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Juridical facts in housing law by V. A. Kroitor

“…The purpose of the article is to define juridical facts of housing law considering modern challenges. Achieving the research purpose became possible through the usage of a set of general scientific and special methods of scientific cognition, in particular, the dialectical, axiological, structural and logical, formal and legal methods were used. …”
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Scientometric Assessment of Global Research Output about Monkeypox during 1970–2022 by Brij Mohan Gupta, Mallikarjun Kappi, Manish Mohan Gore, Atul Gupta

“…Results and Conclusion: The findings reveal that the most productive year of publication was 2003 which included 62 publications with the majority published in Emerging Infectious Diseases (35 papers) and Journal of Virology (32 papers) and Science (60.6), and Morbidity and Mortality Weekly Reports (60.44) achieved the highest citation impact per paper. USA (55.37% share), UK (6.63% share), and Germany (6.11% share) are the most productive countries, and Switzerland (47.93 and 1.84), Canada (46.57 and 1.79), and Belgium (37.32 and 1.43) are the most impactful countries. …”
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Trends in the use of information and communication technologies in the teaching of foreign languages and translator training by N. Kovalchuk

“…It outlines the trends identified by these studies, the achievements to date and the most promising areas for further research. …”
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Tuning Electronic Structure and Optical Properties of Monolayered h-BN by Doping C, Cu and Al by Qun Li, Tengchao Gao, Kuo Zhang, Xiangming Che, Guolong Ni

“…The results show that the C ortho-doped h-BN (BCN) structure with a band gap of 3.05 eV is relatively stable, which is selected as a substate to achieve the Cu-Al co-doped h-BN. Based on this, the effect of the concentration of C atom doping on the electronic and optical properties of Cu-Al co-doped BC_xN (x = 0, 11.1% and 22.2%) is investigated. …”
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Batch biosorption studies of ammonical nitrogen (NH3-N) ions from aqueous solutions using the ubiquitous bacteria Klebsiella sp.: equilibrium, kinetic, and thermodynamic studies by Fadaa Alown, Fuad Ameen, Ashiwin Vadiveloo

“…This study identified the optimal method for the absorption of ammonical nitrogen (NH3-N) from a solution at a concentration of 100 parts per million (ppm), achieving an efficiency of 89 ± 1.5% mg/g under specified conditions. …”
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Clinical Effect and Rotational Stability of TICL in the Treatment of Myopic Astigmatism by Manhui Zhu, Linling Zhu, Qiujian Zhu, Cailian Xu, Peng Yu, Haiyang Xiao, Ying Wang, You Yuan

“…Postoperative rotation was defined as the angle between the intended axis and the achieved axis. Regression analysis was used to investigate the possible risk factors for TICL rotation postoperatively. …”
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La institución matrimonial después del matrimonio homosexual by Beatriz Gimeno, Violeta Barrientos

“…Dos, siendo el matrimonio homosexual una contradicción en sí mismo; esto es, desde la red de sentidos y prácticas que integra, este reconocimiento conlleva el desbordamiento mismo de dicha institución.This article posits the idea that the recognition of homosexual marriage (compared to other types of initiatives which have been achieved by the Spanish LGTB movement) is a non-reformist reform. …”
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