Electrochemical Detection of Dopamine with Graphene Oxide Carbon Dots Modified Electrodes by Omar Isaac Torres-Soto, Alejandro Vega-Rios, Rocio B. Dominguez, Velia Osuna

“…The synergistic effects of electrostatic attraction from glassy carbon electrode negatively charged surface, functionalization for inner-sphere mechanism, and edge effect from lower particle size resulted in amplified electrochemical signal achieving detection at nanomolar level using AMP and DPV. …”
Get full text

Proximally based sural artery flap for the reconstruction of soft tissue defects around the knee and proximal third of the leg in India: a clinical study by Lakshmi Palukuri, Sreedharala Srinivas, Dharmapuri Madhulika, Sanujit Pawde, Ajo Sebastian, Swathi Sankar, Sandeep Reddy Chintha

“…In all cases, donor site closure was achieved with split skin grafting. This flap consistently provided a thin, pliable, stable, and durable soft tissue cover over the defect with no functional deficit and minimal donor site morbidity. …”
Get full text

Innovative activity of Polish enterprises – a strategic aspect. The similarity of NACE divisions by Edyta Bielińska-Dusza, Monika Hamerska

“…Strategic innovativeness, which is a long-term process that takes into account the interpenetration of various types of innovation together with strategic thinking, can be an effective tool for achieving high operating efficiency and maintaining a competitive advantage in the market. …”
Get full text

Diagnostic delay in cerebral creatine deficiency disorders: lessons learned from a cross-sectional single center study, and guanidinoacetate and creatine measurements in Switzerlan... by Christina Kaufman, Anaïs D’Andrea, Annette Hackenberg, Martin Poms, Olivier Braissant, Johannes Häberle

“…Early treatment initiation is essential in AGAT and GAMT deficiencies to achieve a favorable outcome. This study describes the CCDD patient cohort in a single center, and an analysis of the referrals to two Swiss laboratories in Lausanne and Zurich between 2015 and 2023 for the two marker metabolites guanidinoacetate and creatine. …”
Get full text

Optimization of meropenem continuous infusion based on Monte Carlo simulation integrating with degradation study. by Nguyen Tran Nam Tien, Vu Ngan Binh, Pham Thi Thanh Ha, Dang Thi Ngoc Lan, Yong-Soon Cho, Nguyen Phuoc Long, Jae-Gook Shin, Nguyen Hoang Anh, Truong Anh Quan, Do Ngoc Tuan, Nguyen Khac Tiep, Pham The Thach, Nguyen Hoang Anh, Vu Dinh Hoa

“…Meropenem CI with 8 h renewal infusion achieved a higher PTA than the extended 3 h infusion, even at the highest degradation condition. …”
Get full text

Ensuring Cybersecurity in the Context of Digital Economy Development by I. A. Sheremet

“…The author concludes that it will impossible to achieve independence and resilience of the Russian information infrastructure without relevant capacity-building in science and technology as well as without training a new generation of S&T personnel.…”
Get full text

Resetting the Hsc70-mediated lysosomal degradation of PD-L1 via a supramolecular meso peptide for the restoration of acquired anti-tumor T cell immunity by Yujia Zhao, Dan Liu, Wenguang Yang, Wangxiao He, Jin Yan, Leiqing Yao

“…To overcome this issue, a meso chimeric peptide PEPPDL1 was designed to specifically bind the PD-1 binding domain of PD-L1 instead of the Hsc70/CMTM6 binding domain, while also binding to Hsc70 to facilitate the dragging of PD-L1 into Hsc70-mediated chaperone-mediated autophagy (CMA), thereby achieving lysosomal degradation. In order to enable internalization into tumor cells, supramolecular engineering techniques were employed through terminal modification involving sulfydryl and monovalent gold ion (Au(I)), both facilitating self-assembly of modified PEPPDL1 into supramolecular nanospheres termed CTAC-PDL1 driven by aurophilic interaction. …”
Get full text

Evaluation of the planting performance for planting substrate using the SQI-CRITIC combination model based on the least squares method by Ning Wang, Dong Xia, Dong Xia, Dong Xia, Xiaoming Duan, Bingqin Zhao, Bingqin Zhao, Wennian Xu, Wennian Xu

“…Photosynthetic rate (1.97 μmol∙m−2∙s−1) and transpiration rate (0.25 mmol∙m−2∙s−1) were significantly higher than the other fitness ratio components (P < 0.05), while the stomatal width (87.03 μm) was the largest and stomatal density (19.6%) was the lowest (P < 0.05). (2) The results calculated by the SQI-CRITIC combination model based on the least square method are scientific and effective, more accurate and in line with the actual situation. (3) The comprehensive analysis recommended the use of a quality mix ratio (mixture of sediment, amendment of habitat material, organic matter, cement = 100:3:12:4) in ecological restoration to achieve the best plant growth and ecological restoration effect.ConclusionThe experimental results can be extended to more areas that need to use sandy soil for ecological restoration, with a view to providing a theoretical basis for soil quality evaluation, soil and water conservation control, and ecological construction in the Yellow River Basin.…”
Get full text

Deep learning model based prediction of vehicle CO2 emissions with eXplainable AI integration for sustainable environment by Gazi Mohammad Imdadul Alam, Sharia Arfin Tanim, Sumit Kanti Sarker, Yutaka Watanobe, Rashedul Islam, M. F. Mridha, Kamruddin Nur

“…The proposed model was optimized by hyperparameter tuning and achieved excellent performance metrics, such as a high R-squared value of 0.9938 and a low Mean Squared Error (MSE) of 0.0002. …”
Get full text

An Approach to Reduce Tuning Sensitivity in the PIC-Based Optoelectronic Oscillator by Controlling the Phase Shift in Its Feedback Loop by Vladislav Ivanov, Ivan Stepanov, Grigory Voronkov, Ruslan Kutluyarov, Elizaveta Grakhova

“…This paper presents a novel approach for continuously controlling the output frequency of an optoelectronic oscillator (OEO) based on integrated photonics. This is achieved by tuning an integrated optical delay line within a feedback loop. …”
Get full text

Thermodynamic Analysis and Optimization of Secondary Overheating Parameters in Turbo-Expander Plants on Low Boiling Working Fluids by A. V. Ovsyannik, V. P. Kliuchinski

“…At a pressure below the critical pressure, overheating leads to a decrease in the exergetic efficiency, and the maximum exergetic effect is achieved in the absence of a secondary steam superheater. …”
Get full text

Many-body expansion based machine learning models for octahedral transition metal complexes by Ralf Meyer, Daniel B K Chu, Heather J Kulik

“…On a test set composed of all possible isomers of binary TMCs, the best MBE models achieve mean absolute errors (MAEs) of 2.75 kcal mol ^−1 on spin-splitting energies and 0.26 eV on frontier orbital energy gaps, a 30%–40% reduction in error compared to models based on our previous approach. …”
Get full text

Analyzing frequency spectrum and Total Harmonic Distortion for high switching frequency operation of GaN-based filter-less multilevel cascaded H-bridge inverter by Ramkrishna Mishan, Xingang Fu, Chanakya Hingu, Poria Fajri

“…This investigation delves into the capability of GaN switches to achieve MHz switching frequencies within symmetric, higher multilevel cascaded H-bridge (CHB) configurations. …”
Get full text

Effect of Camel Milk on the Physicochemical, Rheological, and Sensory Qualities of Bread by Noha M. Almoraie, Israa M. Shatwan

“…An increase in bread production has been achieved to meet the increasing demand of the growing population. …”
Get full text

Adsorption of phenol on activated carbon obtained from date palm branches by Sameh Ahmed, E. S. Gogina, N. A. Makisha

“…The maximum efficiency of phenol adsorption was achieved at pH 7. In addition, phenol adsorption was well described by the kinetics of the pseudo second order with K2 = 0.0503 g/(mg·min). …”
Get full text

Psicologia baseada em evidências: conhecimento científico na tomada de decisão by Maria Imaculada Cardoso Sampaio, Aparecida Angélica Zoqui Paulovic Sabadi

“…El conocimiento científico aclara, sustenta y respalda la toma de decisión y es la sociedad la gran beneficiaria de los resultados de la ciencia. …”
Get full text

Relationship between the learning gains and learning style preferences among students from the school of medicine and health sciences by Blanca Bazán-Perkins, José Alfredo Santibañez-Salgado

“…Additionally, it is recommended that students work collaboratively, share and discuss learning materials, foster innovation and abstract learning, and follow logical and sequential approaches to optimize their educational achievements. It is fundamental to find learning models that improve the academic performance of students with a reflective learning preference.…”
Get full text

Social Structure Analysis in Management of South Sumatra Inland Waters by Fevi Rahma Dwi Putri, Arif Satria, Rilus A. Kinseng, Taryono Taryono

“…This research aimed to analyze social structure in the inland waters of South Sumatra in the practice of the Lebak Lebung and River Auction (L3S) in OKI District. To achieve this goal, a constructivist paradigm with qualitative research methods was employed, and the sample comprised 39 informants selected as subjects. …”
Get full text

PERSPECTIVES ON THE CHALLENGES TO THE WATCHDOG FUNCTION OF THE MEDIA IN NIGERIA by EMMANUEL OMULA, ROSELINE OGBOLE

“…The study has shown that the media as a watchdog of the society cannot achieve desired result in Nigeria, because our institutions are weak, compromised or corrupt and power does not reside in the people. …”
Get full text

Universal conditional networks (UniCoN) for multi-age embryonic cartilage segmentation with Sparsely annotated data by Nishchal Sapkota, Yejia Zhang, Zihao Zhao, Maria Jose Gomez, Yuhan Hsi, Jordan A. Wilson, Kazuhiko Kawasaki, Greg Holmes, Meng Wu, Ethylin Wang Jabs, Joan T. Richtsmeier, Susan M. Motch Perrine, Danny Z. Chen

“…Extensive experiments on multi-age cartilage segmentation datasets show significant and consistent performance improvements when integrating our conditional modules into popular DL segmentation architectures. On average, we achieve a 1.7% Dice score increase with minimal computational overhead and a 7.5% improvement on unseen data. …”
Get full text