Metabolic reprogramming and immunological changes in the microenvironment of esophageal cancer: future directions and prospects by Zhi-Xun Guo, Jia-Li Ma, Jin-Qiu Zhang, Ling-Ling Yan, Ying Zhou, Xin-li Mao, Xin-li Mao, Xin-li Mao, Shao-Wei Li, Shao-Wei Li, Shao-Wei Li, Xian-Bin Zhou, Xian-Bin Zhou, Xian-Bin Zhou

“…Metabolic reprogramming in tumors frequently coincides with aberrant immune function alterations, and extensive research has demonstrated that perturbations in energy metabolism within the tumor microenvironment influence the occurrence and progression of esophageal cancer. …”
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Flow cytometric characterisation of acute leukaemia in adolescent and adult Ethiopians by Jemal Alemu, Balako Gumi, Aster Tsegaye, Abdulaziz Sherif, Fisihatsion Tadesse, Amha Gebremedhin, Rawleigh Howe

“…An unexpectedly high number of T-cell ALL cases that lacked surface CD3 were observed to have significantly higher levels of aberrantly expressed myeloid markers. Conclusion: We observed multiple phenotypes identifying subtypes of acute leukaemia cases, extending our previous studies in Ethiopia. …”
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Prenatal ultrasound diagnosis, associated anomalies and pregnancy outcomes of fetal right aortic arch by Yuting Xie, Zongjie Weng, Ronghua Wang, Qiumei Wu, Wen Ling, Jinwen Chen, Shan Guo

“…In terms of typing, 78 cases (49.7%) of right aortic arch-aberrant left subclavian artery (RAA-ALSA) and 75 cases (47.8%) of right aortic arch-mirror branch (RAA-MB), 3 cases (1.9%) of right aortic arch-isolated left subclavian artery (RAA-ILSA) and 1 case (0.6%) of right aortic arch-isolated left innominate artery (RAA-ILINA) were identified, and the incidence of combined cardiac anomalies and chromosomal anomalies was significantly greater in the RAA-MB group than the RAA-ALSA group. …”
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Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes by Shuai Zhang, Ruixue Wang, Kun Luo, Shipeng Gu, Xinyu Liu, Junhan Wang, Ludan Zhang, Lin Sun

“…N6-methyladenosine (m6A) in eukaryotic RNA is an epigenetic modification that is critical for RNA metabolism, gene expression regulation, and the development of organisms. Aberrant expression of m6A components appears in a variety of human diseases. …”
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Effects of intranasal oxytocin on neural reward processing in children and adolescents with reactive attachment disorder: A randomized controlled trial by Shinichiro Takiguchi, Shinichiro Takiguchi, Kai Makita, Takashi X. Fujisawa, Takashi X. Fujisawa, Shota Nishitani, Shota Nishitani, Akemi Tomoda, Akemi Tomoda, Akemi Tomoda

“…Children and adolescents with RAD show aberrant attachment behaviors, and existing psychotherapies are difficult to maintain; therefore, pharmacological interventions to aid and boost treatment responses are needed. …”
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HP1 Promotes the Centromeric Localization of ATRX and Protects Cohesion by Interfering Wapl Activity in Mitosis by Erchen Zhang, Lei Peng, Kejia Yuan, Zexian Ding, Qi Yi

“…ATRX deficiency causes aberrant mitosis and decreased centromeric cohesion. …”
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Meta-analysis of the association between overexpression of RAD51 family genes and prognosis and clinical features in breast cancer by Yong-Cheng Liu, Jun Shen

“…Abstract The RAD51 family of genes play a crucial role in the repair of DNA damage, and increasing evidence suggests a close link between the aberrant expression of RAD51 family genes and the development of breast cancer. …”
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Exploring the comorbidity mechanisms between atherosclerosis and hashimoto’s thyroiditis based on microarray and single-cell sequencing analysis by Yirong Ma, Shuguang Wu, Junyu Lai, Qiang Wan, Jingxuan Hu, Yanhong Liu, Ziyi Zhou, Jianguang Wu

“…This study proposes that an aberrant immune response might represent a shared pathogenic mechanism in AS and HT. …”
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Nanopore-based random genomic sampling for intraoperative molecular diagnosis by Francesco E. Emiliani, Abdol Aziz Ould Ismail, Edward G. Hughes, Gregory J. Tsongalis, George J. Zanazzi, Chun-Chieh Lin

“…Furthermore, we validated iSCORED’s real-time applicability in 15 diagnostically challenging primary brain tumors, achieving 100% concordance in detecting aberrant CNV detection, including diagnostic chromosomal gains/losses and oncogene amplifications (10/10). …”
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Imaging Flow Cytometric Identification of Chromosomal Defects in Paediatric Acute Lymphoblastic Leukaemia by Ana P. A. Simpson, Carly E. George, Henry Y. L. Hui, Ravi Doddi, Rishi S. Kotecha, Kathy A. Fuller, Wendy N. Erber

“…It may be characterised by multiple known recurrent genetic aberrations that inform prognosis, the most common being hyperdiploidy and t(12;21) <i>ETV6::RUNX1</i>. …”
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Identification of Crucial lncRNAs for Luminal A Breast Cancer through RNA Sequencing by Xinjian Jia, Hai Lei, Xuemei Jiang, Ying Yi, Xue Luo, Junyan Li, Yu Chen, Sha Liu, Chengcheng Yang

“…The growing body of evidence indicates aberrant expression of long noncoding RNAs (lncRNAs) in breast cancer. …”
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De Novo Acute Myeloid Leukemia with Combined CBFB-MYH11 and BCR-ABL1 Gene Rearrangements: A Case Report and Review of Literature by Venkata Rakesh Sethapati, Ra’ed Jabr, Leyla Shune, Wissam El Atrouni, Patrick R. Gonzales, Wei Cui, Shivani Golem

“…Additionally, inv(16) can cooperate with other genetic aberrations to further increase cell proliferation. …”
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Response of tef (Eragrostis tef (Zucc.) Trotter) yield to nutrient management under rainy and irrigation production systems in northwestern Amhara, Ethiopia. by Zerfu Bazie, Tadele Amare, Erkihun Alemu, Bitewulign Kerebh, Abere Tenagn, Abrham Awoke, Zmie Ambaw, Beamlaku Alemayehu, Anteneh Abewa, Ataklte Abebe, Tesfaye Feyisa, Birhanu Agumas

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Economic Valuation of Ecosystem Services and Its Association with Socioeconomic Factors in the Wof-Washa Natural State Forest, North Shewa Zone, Ethiopia by Abere Wondimu Kassie, Admasu Moges, Tilahun Alelign, Gojam Bayeh

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A Standardized Classification Scheme for Gastroduodenal Disorder Evaluation Using the Gastric Alimetry System: Prospective Cohort Study by Chris Varghese, Gabriel Schamberg, Emma Uren, Stefan Calder, Mikaela Law, Daphne Foong, Vincent Ho, Billy Wu, I-Hsuan Huang, Peng Du, Thomas Abell, Charlotte Daker, Christopher N. Andrews, Armen A. Gharibans, Gregory O’Grady

“…Patients underwent Gastric Alimetry profiling, and a standardized digital classification framework was devised and applied to separate patients into those with a) abnormal spectral analyses (ie aberrant gastric frequencies, amplitudes, and rhythms); and normal spectral analyses with b) symptoms correlated to gastric amplitude (subgroups: sensorimotor, postgastric, and activity-relieved), and c) symptoms independent of gastric amplitude (subgroups: continuous, meal-relieved, meal-induced). …”
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The discovery and characterization of K‐563, a novel inhibitor of the Keap1/Nrf2 pathway produced by Streptomyces sp by Ran Hori, Kozo Yamaguchi, Hidetaka Sato, Miwa Watanabe, Kyoko Tsutsumi, Susumu Iwamoto, Masayuki Abe, Hideyuki Onodera, Satoshi Nakamura, Ryuichiro Nakai

“…Previous reports found that aberrant Keap1/Nrf2 pathway activation due to Kelch‐like ECH‐associated protein 1 (Keap1) mutations or Nuclear factor E2‐related factor 2 (Nrf2) mutations induced resistance of cancer cells to chemotherapy and accelerated cell growth via the supply of nutrients. …”
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Identification and functional analysis of a novel SMARCC2 splicing variant in a family with syndromic neurodevelopmental disorder by Ming Li, Jingqi Lin, Hongjun Fei, Jinyu Liu, Yiyao Chen, Xu Han, Yanlin Wang, Jian Wang, Renyi Hua, Shuyuan Li, Niu Li

“…TA-clone sequencing of the RT-PCR fragments showed that the canonical splicing variant resulted in two distinct aberrant splicing events in SMARCC2 mRNA. Specifically, approximately 80% of the mutant clones resulted from the in-frame insertion of 126 bases in intron 16, while the remaining 20% showed an in-frame deletion of exon 16 (c.1383_1496del). …”
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Dynamic functional connectivity patterns predict early antidepressant treatment response in drug-naïve, first-episode adolescent MDD by Maojia Ran, Hang Zhang, Meijiang Jin, Yuanmei Tao, Hanmei Xu, Shoukang Zou, Zhujun Wang, Fang Deng, Lijuan Huang, Hong Zhang, Xiaowei Tang, Yanping Wang, Xia Fu, Li Yin, Li Yin, Li Yin

“…ObjectiveAdolescents with major depressive disorder (MDD) exhibit abnormal dynamic functional connectivity (dFC) patterns, but it remains unclear whether these aberrant dFC patterns are linked to antidepressant treatment. …”
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Performance analysis of Leica Biosystems p16 monoclonal antibody in oropharyngeal squamous cell carcinoma by Selvam Thavaraj, Max Robinson, Shubham Dayal, Claire Bowen

“…HPV 16’s E6 and E7 oncoproteins bind and inactivate p53 and retinoblastoma (Rb) tumor-suppressing genes. This causes aberrant over-expression of the cell cycle inhibitor gene, p16, leading to tumorigenesis. …”
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Frekuensi HBsAg Positif pada Uji Saring Darah di Palang Merah Indonesia Cabang Padang Tahun 2012 by Nadia Ventiani, Susila Lastri, Dian Pratiwi

“…The result of research showed percentage of blooddonorswithpositiveHBsAgwere3.61%. HBsAg positive from male donors were 93.22%, and HBsAg positive from female donors were 6.78%. …”
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