The Role of PPAR Gamma in Systemic Sclerosis by Andréa Tavares Dantas, Michelly Cristiny Pereira, Moacyr Jesus Barreto de Melo Rego, Laurindo Ferreira da Rocha, Ivan da Rocha Pitta, Cláudia Diniz Lopes Marques, Angela Luzia Branco Pinto Duarte, Maira Galdino da Rocha Pitta

“…Recently, antifibrotic effects of PPARγ ligands have been studied in vitro and in vivo and some theories have emerged leading to new insights. Aberrant PPARγ function seems to be implicated in pathological fibrosis in the skin and lungs. …”
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Circulating LncRNA Is Potentially Up-regulated in Coronary Artery Disease by Niloofar Avazpour, Mohammadreza Hajjari, Saeed Yazdankhah, Azita Sahni, Ali Mohammad Foroughmand

“…Recent studies have revealed that aberrantly regulated long non-coding RNA (lncRNA) as one of the main classes of cellular transcript plays a key regulatory role in transcriptional and epigenetic pathways. …”
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Atomic-scale understanding of the effects of Cr and Ti on γ′ growth kinetics in the Ni–Al-X ternary system: Diffusion couple technique and DFT study by Xinyu Gao, Yuan Tian, Xin Wen, Shichang Qiao, Fengzhen Wang, Na Li, Zhikang Xia, Yongqianag Wang, Shuai Liu, Chao Yuan

“…This study investigates the temporal evolution of γ′ phase in Ni–Al-X (X = Cr, Ti) system, utilizing diffusion-couple alongside aberration-corrected transmission electron microscopy to unveil atomic-scale effects. …”
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A Toxicological Evaluation of a Standardized Hydrogenated Extract of Curcumin (CuroWhite™) by Alastimmanahalli Narasimhiah Ravikumar, Joby Jacob, Sreeraj Gopi, Tumkur Subbarao Jagannath

“…The test item was not mutagenic in the bacterial reverse mutation test or in vitro mammalian chromosomal aberration test, and no in vivo genotoxic activity was observed in rat bone marrow in the micronucleus test. …”
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Beneficial effects of baicalein on a model of allergic rhinitis by Liu Tao, Xu Jing, Wu Yungang, Li Xiaoxia, Ding Detao, Ma Dengdian, Yao Mengwei, Wei Wenzhong, Zhang Wei, Wang Shaohua, Yao Jing, Li Xiaoyu

“…Baicalein attenuated histological alterations, aberrant tissue repair and inflammation after OVA-induced AR. …”
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Testing rTMS-Induced Neuroplasticity: A Single Case Study of Focal Hand Dystonia by Sonia Betti, Andrea Spoto, Umberto Castiello, Luisa Sartori

“…Focal hand dystonia in musicians is a neurological motor disorder in which aberrant plasticity is caused by excessive repetitive use. …”
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Multi-GPU Development of a Neural Networks Based Reconstructor for Adaptive Optics by Carlos González-Gutiérrez, María Luisa Sánchez-Rodríguez, José Luis Calvo-Rolle, Francisco Javier de Cos Juez

“…Aberrations introduced by the atmospheric turbulence in large telescopes are compensated using adaptive optics systems, where the use of deformable mirrors and multiple sensors relies on complex control systems. …”
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Gall bladder duplication: A rare biliary malformation by Hari Om Joshi, MBBS, MD, Dipesh Poudel, MBBS, MA, Prashant Khatiwoda, MBBS, MD, Bikash Bikram Adhikari, MBBS, MD, Laxman Kunwar, MBBS, MD

“…Gallbladder duplication is a rare anatomical variation with an incidence of approximately 1 in 3800 to 4000 live births, resulting from aberrant biliary organogenesis. This case report discusses a 35-year-old female who presented with intermittent lower abdominal pain, with initial imaging revealing a complex left adnexal cyst. …”
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Immunotherapy of Cancer: Reprogramming Tumor-Immune Crosstalk by Kyle K. Payne, Amir A. Toor, Xiang-Yang Wang, Masoud H. Manjili

“…Recent studies suggest that aberrant expression of cancer testis antigens (CTAs) can generate robust antitumor immune responses, which implicates CTAs as potential targets for immunotherapy. …”
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Wnt5a Signaling in Normal and Cancer Stem Cells by Yan Zhou, Thomas J. Kipps, Suping Zhang

“…Wnt5a signaling is critical for regulating normal developmental processes, including stem cell self-renewal, proliferation, differentiation, migration, adhesion, and polarity. Moreover, the aberrant activation or inhibition of Wnt5a signaling is emerging as an important event in cancer progression, exerting both oncogenic and tumor suppressive effects. …”
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PRESERVATION OF THE GENE POOL OF PLANTS UNDER IN PERMAFROST CONDITIONS: STATE, ADVANTAGES, AND PROSPECTS by B. M. Kershengolts, I. F. Zhimulev, N. P. Goncharov, R. V. Chzhan, G. V. Filippova, A. A. Shein, I. A. Prokopiev

“…The observed number of chromosomal aberrations in root meristem cells did not increase, except P. sativum cv. …”
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Comparative Glycopeptide Analysis for Protein Glycosylation by Liquid Chromatography and Tandem Mass Spectrometry: Variation in Glycosylation Patterns of Site-Directed Mutagenized... by Young Hye Hahm, Sung Ho Hahm, Hyoun Young Jo, Yeong Hee Ahn

“…This mapping method, focusing on precise glycopeptide identification and comparison for the identified glycoforms, can be useful in differentiating aberrant glycosylation in biosimilar rAb products.…”
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Unexpected Abscess Localization of the Anterior Abdominal Wall in an ADPKD Patient Undergoing Hemodialysis by Nikos Sabanis, Eleni Paschou, Eleni Gavriilaki, Maria Mourounoglou, Sotirios Vasileiou

“…Although the precise pathway of infection remains uncertain, the previous medical history as well as the clinical course of our patient led us to hypothesize an alternative route of infection from the gastrointestinal tract through an aberrant intestinal barrier into the bloodstream and eventually to an atypical location.…”
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Decoding the mechanisms behind second primary cancers by Meiyuan Zeng, Anqi Lin, Aimin Jiang, Zhengang Qiu, Hongman Zhang, Shifu Chen, Mingyan Xu, Zaoqu Liu, Quan Cheng, Jian Zhang, Peng Luo

“…This review summarizes recent studies on the mechanisms of SPCs, including the roles of genomic changes after first primary cancer (FPC) treatments, stromal cell phenotypic and metabolic changes, hormone levels and receptor expression, immunosuppression, aberrant gene methylation, EGFR signaling, and cell-free DNA in SPC development. …”
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Modulatory Function of Invariant Natural Killer T Cells in Systemic Lupus Erythematosus by Yi-Ping Chuang, Chih-Hung Wang, Ning-Chi Wang, Deh-Ming Chang, Huey-Kang Sytwu

“…Studies of SLE-susceptible loci and the cellular and humoral immune responses reveal variable aberrations associated with this systemic disease. Invariant natural killer T (iNKT) cells are a unique subset of lymphocytes that control peripheral tolerance. …”
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Classification of Colon Cancer Patients Based on the Methylation Patterns of Promoters by Wonyoung Choi, Jungwoo Lee, Jin-Young Lee, Sun-Min Lee, Da-Won Kim, Young-Joon Kim

“…In addition, we analyzed the functional ontology of aberrantly methylated genes and identified the G-protein-coupled receptor signaling pathway as one of the major pathways affected epigenetically. …”
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Methylation-Demethylation Dynamics: Implications of Changes in Acute Kidney Injury by Anubhav Chakraborty, Pragasam Viswanathan

“…Since acute kidney injury (AKI), a major risk factor for chronic kidney disease and death, is characterised by aberrant expression of genes, understanding the dynamics of methylation and demethylation will provide new insights into the intricacies of the disease. …”
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GSK-3β at the Intersection of Neuronal Plasticity and Neurodegeneration by Tomasz Jaworski, Ewa Banach-Kasper, Katarzyna Gralec

“…Here, we provide an overview of how GSK-3β is regulated in physiological synaptic plasticity and how aberrant GSK-3β activity contributes to the development of dysfunctional synaptic plasticity in neuropsychiatric and neurodegenerative disorders.…”
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The Role of Methylation in Chronic Lymphocytic Leukemia and Its Prognostic and Therapeutic Impacts in the Disease: A Systematic Review by Sevastianos Chatzidavid, Christina-Nefeli Kontandreopoulou, Nefeli Giannakopoulou, Panagiotis T. Diamantopoulos, Christos Stafylidis, Marie-Christine Kyrtsonis, Maria Dimou, Panayiotis Panayiotidis, Nora-Athina Viniou

“…Epigenetic regulation has been thoroughly investigated in recent years and has emerged as an important aspect of chronic lymphocytic leukemia (CLL) biology. Characteristic aberrant features such as methylation patterns and global DNA hypomethylation were the early findings of the research during the last decades. …”
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Role of Cytokines and Toll-Like Receptors in the Immunopathogenesis of Guillain-Barré Syndrome by Kishan Kumar Nyati, Kashi Nath Prasad

“…Guillain-Barré syndrome (GBS) is an autoimmune disease of the peripheral nervous system, mostly triggered by an aberrant immune response to an infectious pathogen. …”
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