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3501
TLR7/8/9 agonists and low-dose cisplatin synergistically promotes tertiary lymphatic structure formation and antitumor immunity
Published 2025-01-01“…In mouse models, the cisplatin+CR108 combination significantly outperformed cisplatin or CR108 alone in abrogating established 4T1 and B16 tumors. The synergistic antitumor effects of cisplatin and CR108 were accompanied by markedly increased tumor tertiary lymphatic structures (TLS) formation, higher levels of type I and III interferons and TNF-α in serum, augmented T and B lymphocyte infiltration, antigen-presenting cell activation, as well as reduced functionally of exhausted T cells. …”
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3502
Physical Activity and Quality of Life in Retinitis Pigmentosa
Published 2017-01-01“…Purpose. Aerobic exercise has been found to be neuroprotective in animal models of retinal degeneration. …”
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3503
Effect of Black Cumin on the Expression of Genes Related to Lipid Metabolism in Adipose Tissue: A Mouse Model Study
Published 2024-02-01“…Total RNA was extracted, and after the qualification by agarose gel electrophoresis, cDNA was synthesized. …”
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3504
Inhibitory Effects of a Novel PPAR-γ Agonist MEKT1 on Pomc Expression/ACTH Secretion in AtT20 Cells
Published 2018-01-01“…SiRNA-mediated PPAR-γ knockdown significantly abrogated MEKT1-mediated Pomc mRNA suppression. ACTH secretion from AtT20 cells was also significantly inhibited by MEKT1. …”
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3505
Current practices in physical fitness assessment and monitoring among coaches of individual and team sports: a survey in Portugal, Spain, and Romania
Published 2024-04-01“…Portuguese and Spanish coaches predominantly favor aerobic tests (50% and 46.8% respectively), whereas Romanian coaches exhibit a preference for sprint (56.9%) and skill tests (52.3%). …”
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3506
Triggering Oxygen Redox Cycles in Nickel Ferrite by Octahedral Geometry Engineering for Enhancing Oxygen Evolution
Published 2025-02-01“…Herein, to trigger the LOM pathway while maintaining high stability, iron foam (IF)‐supported Ni0.75Fe2.25O4 (NiFeO) with geometrical defects of [NiO6] (nickel cation coordinated with six oxygen anions) units and higher ratio of Fe to Ni cations in octahedral sites (d‐NiFeHRO/IF) is prepared by ion‐exchanging with polar aprotic solvent followed by annealing. As a result, as‐synthesized d‐NiFeHRO/IF exhibits excellent activity (at 295 mV overpotential to achieve 100 mA cm−2), fast kinetics (Tafel slope of only 34.6 mV dec−1), and high stability (maintaining a current density of 100 mA cm−2 over 130 h) for the OER. …”
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3507
Organic matter from biofilter nitrification by high performance size exclusion chromatography and fluorescence excitation-emission matrix
Published 2020-04-01“…The batch scale of bionet nitrification without organic carbon substrate under aerobic conditions was operated for around 150 minutes. …”
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3508
Pollutant removal by Canna Generalis in tropical constructed wetlands for domestic wastewater treatment
Published 2019-07-01“…Two kinds of hybrid constructed wetlands were employed, including Facultative pond combined with free water sub-surface constructed wetlands system and horizontal subsurface flow combined with Aerobic pond system. It was found that the ponds played an important role in the hybrid system performance and enhanced the performance of constructed wetlands. …”
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3509
Genetic Analysis of Sodium Channel Genes in Pediatric Epilepsy Patients of Pakistan
Published 2022-01-01“…The DNA was isolated, amplified by PCR, and then, was run through 1% agarose gel. The sequencing was performed, and the sequences were observed through BioEdit software for any change in DNA sequence. …”
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3510
Natural Killer Cells from Malignant Pleural Effusion Are Endowed with a Decidual-Like Proangiogenic Polarization
Published 2018-01-01“…Addition of TGFβ or cell-free pleural fluid to IL-2 in the culture medium abrogated NK cell CD107a and IFNγ expression even in healthy donors (n = 14) NK. …”
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3511
Synthesis, Spectroscopic Characterization, and Biological Evaluation Studies of 5-Bromo-3-(((hydroxy-2-methylquinolin-7-yl)methylene)hydrazono)indolin-2-one and Its Metal (II) Comp...
Published 2014-01-01“…The DNA cleavage activities of all the complexes were studied by agarose gel electrophoresis method. In addition, the free ligand along with its complexes has been studied for their antioxidant activity.…”
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3512
Influence of composting and thermal processing on the survival of microbial pathogens and nutritional status of Nigeria sewage sludge
Published 2017-09-01“…Methods Treated samples were analyzed for physicochemical and microbiological properties using standard analytical and aerobic culture protocols. Results Microbiological analysis of the initial fresh mixture (sewage sludge/sawdust) showed that the total heterotrophic bacteria was 1.17 × 106 CFU/g of fresh compost, coliforms 4.7 × 104 CFU/g, Salmonella sp., and Shigella sp. 7.3 × 104 CFU/g, yeasts and moulds 9.0 × 104 CFU/g. …”
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3513
Identification of genome compositions in allopolyploid species of the genus Elymus(Poaceae: Triticeae) in the Asian part of Russia by CAPS analysis
Published 2020-04-01“…On the basis of nucleotide sequences from public databases, TaqI restrictase was selected, as it produced patterns of restriction fragments specific for St, H, and Y haplomes easily recognizable in agarose gel. A sample of 68 accessions belonging to 32 species was analyzed. …”
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3514
Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs
Published 2018-01-01“…In contrast, the conditioned medium from senescent fibroblasts that upregulated NF-κB activity altered deoxycytidine kinase levels in drug-untreated CRC cells and abrogated DAC effect on degradation of DNA methyltransferase 1. …”
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3515
Effects of physical exercise in reducing caregivers burden: a systematic review
Published 2025-02-01“…The reviewed programs encompassed aerobics, strengthening, and muscle relaxation exercises, delivered by various professionals in diverse settings, such as caregivers' homes, gyms, and hospital environments. …”
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3516
Characterization of composting process and chemical composition of compost from recycling centers in Surabaya City, Indonesia
Published 2024-03-01“…Notably, composting occurred within an open aerobic system devoid of bio-activators. Chemical analysis revealed: C/N ratio (17.10 - 19.60), C-total (17.65% - 18.10%), N-total (0.95% - 1.12%), P2O5 (0.35% - 0.51%), K2O (0.39% - 0.41%), Cu (1.65 ppm - 2.01 ppm), Pb (2.05 ppm - 3.11 ppm), Cd (0.11 ppm - 0.24 ppm), and Zn (1.02 ppm - 1.14 ppm). …”
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3517
Cu(II) and Ni(II) Complexes with New Tridentate NNS Thiosemicarbazones: Synthesis, Characterisation, DNA Interaction, and Antibacterial Activity
Published 2019-01-01“…The activities of these compounds against oxidative DNA cleavage were examined by agarose gel electrophoresis. Cu(II) and Ni(II) complexes can wind DNA strands through groove interactions and promote strand breakage of the plasmid pmCherry under oxidative stress conditions. …”
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3518
Acute and chronic effects of physical exercise on atherosclerosis, kynurenine pathway, endothelial function and inflammation in patients with coronary artery disease: a clinical tr...
Published 2025-02-01“…The second visit will include an endothelial function evaluation using venous occlusion plethysmography and 30 min of moderate-intensity aerobic exercise. Blood samples will be collected pre-exercise and post-exercise. …”
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3519
Prediction of lower-limb isokinetic strength from functional fitness tests in older adults: A 550-participant cross-sectional study
Published 2025-02-01“…Agility and dynamic tests were completed before strength and aerobic resistance tests within the physical fitness tests. …”
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3520
Benefits of physical exercise through multivariate analysis in sedentary adults and elderly: An analysis of physical fitness, health and anthropometrics
Published 2025-02-01“…Significant gains were observed in the 6MWT and elbow flexion and extension (p < 0.05), indicating improvements in aerobic fitness and strength. Multivariate analysis showed that hip circumference, chair stand test, handgrip strength, and agility significantly influenced 6MWT performance. …”
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