Mitochondrial targeting of Candida albicans SPFH proteins and requirement of stomatins for SDS-induced stress tolerance by Hyunjeong Kim, Marienela Y. Heredia, Xiao Chen, Maisha Ahmed, Mohammad Qasim, Tracy L. Callender, Aaron D. Hernday, Jason M. Rauceo

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Refined methodology for quantifying Pseudomonas aeruginosa virulence using Galleria mellonella by Christopher M. R. Axline, Travis J. Kochan, Sophie Nozick, Timothy Ward, Tania Afzal, Issay Niki, Sumitra D. Mitra, Ethan VanGosen, Julia Nelson, Aliki Valdes, David Hynes, William Cheng, Joanne Lee, Prarthana Prashanth, Timothy L. Turner, Nathan B. Pincus, Marc H. Scheetz, Kelly E. R. Bachta, Alan R. Hauser

“…We provide a detailed protocol for using the time at which 50% of larvae have died (LT50) at a particular inoculum as a measure of P. aeruginosa virulence. We also describe a quality control metric for enhancing the reproducibility of LT50 values. …”
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Clinical and microbiological analyses of colistin-resistant strains among carbapenem-resistant Enterobacter cloacae complex clinical isolates by Jinyoung Yang, Jin Yang Baek, Jae-Hoon Ko, Kyungmin Huh, Sun Young Cho, Doo Ryeon Chung, Kyong Ran Peck, Hee Jae Huh, Kwan Soo Ko, Cheol-In Kang

“…ABSTRACT Carbapenem-resistant Enterobacter cloacae complex (CR-ECC), which is rapidly increasing as the cause of nosocomial infections, has limited treatment options. The aim of this study is to investigate the microbiological and clinical traits and molecular epidemiology of isolates of CR-ECC and provide guidance for antibiotic selection in clinical practice. …”
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Farm-to-fork changes in poultry microbiomes and resistomes in Maputo City, Mozambique by Natalie Olson, Frederica Lamar, Hermógenes Mucache, José Fafetine, Joaquim Saíde, Amélia Milisse, Denise R. A. Brito, Kelsey J. Jesser, Karen Levy, Matthew C. Freeman, Maya L. Nadimpalli

“…Many potentially pathogenic bacteria and ARGs present in chicken fecal samples are also present on carcasses sold to consumers. Finally, commercial chicken carcasses contain high-risk ARGs that are not necessarily introduced from chicken feces. …”
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Valine potentiates cefoperazone-sulbactam to kill methicillin-resistant Staphylococcus aureus by Shao-hua Li, Yuan Tao, Zhi-cheng Yang, Huan-zhe Fu, Hui-yin Lin, Xuan-xian Peng, Hui Li

“…Valine promoted MRSA to increase SCF uptake that overcomes the efflux and enzymatic hydrolysis. It also extended the PAE of SCF. These occur because valine activates the pyruvate cycle to elevate proton motive force by NADH and increases membrane permeability by lauric acid. …”
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AI-assisted diagnosis of vulvovaginal candidiasis using cascaded neural networks by Zhongxiao Wang, Ruliang Wang, Haichun Guo, Qiannan Zhao, Huijun Ren, Jumin Niu, Ying Wang, Wei Wu, Bingbing Liang, Xin Yi, Xiaolei Zhang, Shiqi Xu, Xianling Dong, Liqun Wang, Qinping Liao

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Transcriptome analysis reveals that PRV XJ delgE/gI/TK protects against intestinal damage in nose-dropping-infected mice by regulating ECM-ITGA/ITGB-P-FAK by Tong Xu, Yang Zhang, Qian Tao, Lei Xu, Si-Yuan Lai, Yan-Ru Ai, Jian-Bo Huang, Ben-Lu Yang, Ling Zhu, Zhi-Wen Xu

“…Apart from neurological symptoms, diarrhea caused by PRV infection is also an essential cause of mortality in newborn and weaned piglets. …”
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Competence induction of homologous recombination genes protects pneumococcal cells from genotoxic stress by David De Lemos, Anne-Lise Soulet, Violette Morales, Mathieu Berge, Patrice Polard, Calum Johnston

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Analogs of Precambrian microbial communities formed de novo in Caucasian mineral water aquifers by Daria G. Zavarzina, Alexey A. Maslov, Alexander Y. Merkel, Nataliya A. Kharitonova, Alexandra A. Klyukina, Ekaterina I. Baranovskaya, Elena A. Baydariko, Evgeniy G. Potapov, Kseniya S. Zayulina, Andrey Y. Bychkov, Nikolay A. Chernyh, Elizaveta A. Bonch-Osmolovskaya, Sergey N. Gavrilov

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Performance evaluation of the high-throughput quantitative Alinity m Epstein-Barr virus assay by D. Yitzchak Goldstein, Mark M. Sasaki, Momka Narlieva, Nhi Nhan, Tianxi Liu, April Kegl, Tanjina Akter, Tanisha Dickerson, Eriel Thornton, Patricia Jim, Stephen Young, Danijela Lucic, Julie W. Hirschhorn

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Iron triggers TvPI4P5K proteostasis and Arf-mediated cell membrane trafficking to regulate PIP2 signaling crucial for multiple pathogenic activities of the parasitic protozoan Tric... by Kuan-Yi Wu, Yen-Ju Chen, Shu-Fan Lin, Hong-Ming Hsu

“…Additionally, PIP2 replenishment reversed these inhibitions in the T31N mutant, suggesting the critical role of TvArf220 activation in PIP2-calcium signaling. Also, T31N mutant and BFA treatment impaired actin dynamics and cytoskeleton-dependent processes in T. vaginalis, further linking the role of TvArf220 to PIP2-calcium-dependent actin dynamics. …”
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Group a Streptococcus remains viable inside fibrin clots and gains access to human plasminogen for subsequent fibrinolysis and dissemination by Henry M. Vu, Thomas E. Moran, Zhong Liang, Yun-Juan Bao, Paulina G. Carles, Jessica C. Keane, Madelyn G. Cerney, Caitlyn N. Dahnke, Ana L. Flores-Mireles, Victoria A. Ploplis, Francis J. Castellino, Shaun W. Lee

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Magnetic hybrid chitin-horse manure humic acid for optimized Cd(II) and Pb(II) adsorption from aquatic environment by Rahmat Basuki, Yusuf Bramastya Apriliyanto, Elva Stiawan, Adya Rizky Pradipta, Bambang Rusdiarso, Budi Riza Putra

“…HMHA-Ch-Fe3O4 ferromagnetism was exhibited by the vibrating sample magnetometer (VSM), which determined magnetic saturation (Ms) at 40.70 emu/g. …”
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Neospora caninum infection specifically suppresses the expression of a host lncRNA XR_001919077.1 to facilitate parasite propagation by modulating host cell mitochondrial function... by Shan-Shan Zhao, De-Liang Tao, Jin-Ming Chen, Ming-Yi Zhang, Xin Yang, Jun-Ke Song, Qun Liu, Guang-Hui Zhao

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Efficacy of carbonyl cyanide-3-chlorophenylhydrazone in combination with antibiotics against Mycobacterium abscessus by Jifang Zheng, Qiang Liu, Haoran Wang, Fengmin Huo, Junnan Jia, Hairong Huang, Suting Chen

“…Carbonyl cyanide 3-chlorophenylhydrazone (CCCP), a proton pump inhibitor, has shown good bacteriostatic activity against M. abscessus. This study aimed to determine its synergistic antimicrobial effects when combined with commonly used antibiotics. …”
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Differential diversity and structure of autotrophs in agricultural soils of Qinghai Province by Lianyu Zhou, Xuelan Ma, Qiaoyu Luo, Feng Qiao, Huichun Xie, Longrui Wang, Wenjuan Sun, Yu Liu, Yun Ma

“…Soil properties, agronomic management measures, and environmental factors can influence the community composition, abundance, and activity of CO2-assimilating bacteria. This study aims at evaluating the effects of different regions and crop types on the abundance, composition, and activity of CO2-fixing bacteria in agricultural soil.…”
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Bacteria-specific modified nucleoside is released and elevated in urine of patients with bacterial infections by Ryosuke Yamamura, Yu Nagayoshi, Kayo Nishiguchi, Hitomi Kaneko, Keiichi Yamamoto, Koki Matsushita, Miho Shimamura, Akihiro Kunisawa, Korin Sakakida, Takeshi Chujo, Masataka Adachi, Yutaka Kakizoe, Yuichiro Izumi, Takashige Kuwabara, Masashi Mukoyama, Kazuhito Tomizawa

“…Furthermore, we found that m2A was elevated in the urine from animal models of bacterial infection and the urine of patients with bacterial infections. …”
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A unique Helicobacter pylori strain to study gastric cancer development by Jeannette M. Whitmire, Ian H. Windham, Morris O. Makobongo, Mandy D. Westland, Sirena C. Tran, Jaume Piñol, Yvonne Hui, Rasha Raheem Alkarkoushi, Oscar Q. Pich, David J. McGee, M. Blanca Piazuelo, Angela Melton-Celsa, Traci L. Testerman, Timothy L. Cover, D. Scott Merrell

“…The USU101 strain reproducibly colonized Mongolian gerbils and induced gastric inflammation in the majority of the animals 1 month after infection. Adenocarcinoma or dysplasia was observed in the majority of gerbils by 2 months post-infection. …”
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Correlation analysis of the impact of Clonorchis sinensis juvenile on gut microbiota and transcriptome in mice by Xueling Deng, Shitao Li, Yuhong Wu, Jiali Yao, Wei Hou, Jiangyao Zheng, Boying Liang, Xiaole Liang, Qiping Hu, Zhanshuai Wu, Zeli Tang

“…The interplay between gut microbiota and the host transcriptome is crucial for maintaining health; however, the impact of Clonorchiasis sinensis juvenile infection on these factors is still poorly understood. This study aimed to investigate their relationship and potential pathogenic mechanisms. …”
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Integrating microbial profiling and machine learning for inference of drowning sites: a forensic investigation in the Northwest River by Qin Su, Xiaofeng Zhang, Xiaohui Chen, Zhonghao Yu, Weibin Wu, Qingqing Xiang, Chengliang Yang, Jian Zhao, Ling Chen, Quyi Xu, Chao Liu

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