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3941
The alphavirus determinants of intercellular long extension formation
Published 2025-02-01Get full text
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3942
Etoposide targets 2A protease to inhibit enterovirus 71 replication
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3943
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3944
Clinical characteristics, etiology, and treatment of young adult‐onset epilepsy: A 24‐year retrospective study
Published 2025-02-01“…Methods The study included patients with epilepsy aged between 18 and 44 years and aimed to analyze the clinical characteristics of epilepsy in young people and their response to antiseizure medication (ASM) over a 24‐year period (February 1999 and March 2023). …”
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3945
Impact of gut microbial diversity on egg production performance in chickens
Published 2025-02-01“…This research not only advances our understanding of avian gut microbiology but also has practical implications for optimizing poultry farming practices and enhancing economic outcomes.…”
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3946
The palmitoyl-CoA ligase Fum16 is part of a Fusarium verticillioides fumonisin subcluster involved in self-protection
Published 2025-02-01“…ABSTRACT Fusarium verticillioides produces the mycotoxin fumonisin B1 (FB1), which disrupts sphingolipid biosynthesis by inhibiting ceramide synthase and affects the health of plants, animals, and humans. The means by which F. verticillioides protects itself from its own mycotoxin are not completely understood. …”
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3947
Limnospira (Cyanobacteria) chemical fingerprint reveals local molecular adaptation
Published 2025-02-01“…In the present paper, we attempted to determine whether Limnospira displayed metabolic signatures specific to its different habitats. We also sought to understand the impact of the accessory gene repertoire on respective chemical adaptations.…”
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3948
Regulation of human papillomavirus E6 oncoprotein function via a novel ubiquitin ligase FBXO4
Published 2025-02-01“…Interestingly, E6AP not only aids in the E6-directed degradation of cellular substrates but also stabilizes the E6 protein by protecting it from proteasome-mediated degradation. …”
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3949
RNA stability is regulated by both RNA polyadenylation and ATP levels, linking RNA and energy metabolisms in Escherichia coli
Published 2025-01-01“…Above this concentration, changes in ATP levels had no impact on RNA stability. We also demonstrated that some RNAs were stabilized when PAP I was inactivated by low ATP availability. …”
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3950
Delay of innate immune responses following influenza B virus infection affects the development of a robust antibody response in ferrets
Published 2025-02-01“…ABSTRACT Due to its natural influenza susceptibility, clinical signs, transmission, and similar sialic acid residue distribution, the ferret is the primary animal model for human influenza research. Antibodies generated following infection of ferrets with human influenza viruses are used in surveillance to detect antigenic drift and cross-reactivity with vaccine viruses and circulating strains. …”
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3951
Microbial community structure and functional traits involved in the adaptation of culturable bacteria within the gut of amphipods from the deepest ocean
Published 2025-01-01“…This not only complements the current omics-dominated field but also paves the way for future resource development of extreme microbes. …”
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3952
Synthesis of Fe3O4@MIL-101-OH/Chitosan for adsorption and release of doxorubicin
Published 2025-01-01“…Also, this nanocomposite has a high specific surface area (610.36 m2/g). …”
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3953
The protein structurome of Orthornavirae and its dark matter
Published 2025-02-01“…We used protein structure modeling and similarity searches to illuminate the remaining dark matter in hundreds of thousands of orthornavirus genomes. The vast majority of the dark matter domains showed either “generic” folds, such as single α-helices, or no high confidence structure predictions. …”
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3954
Acinetobacter baumannii represses type VI secretion system through a manganese-dependent small RNA-mediated regulation
Published 2025-02-01“…We demonstrate that the abundance of intracellular Mn2+ enables complementary base pairing of AbsR28-tssM mRNA (that translates to TssM, one of the vital inner membrane components of T6SS), inducing RNase E-mediated degradation of tssM mRNA and resulting in T6SS repression. …”
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3955
Whole-genome sequencing and metagenomics reveal diversity and prevalence of Listeria spp. from soil in the Nantahala National Forest
Published 2025-01-01“…Recently, metagenomic sequencing has also been explored as a tool for the detection of Listeria spp. in environmental samples. …”
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3956
Establishing a new human pneumococcal standard reference serum, MPRSS-01
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3957
Accurate phenotype-to-genotype mapping of high-diversity yeast libraries by heat-shock-electroporation (HEEL)
Published 2025-02-01“…Rather than increasing the quantity of measurements, new studies should aim to generate as accurate measurements as possible. …”
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Pseudovibriamides from Pseudovibrio marine sponge bacteria promote flagellar motility via transcriptional modulation
Published 2025-02-01“…The gene cluster that encodes pseudovibriamide biosynthesis is found in two-thirds of Pseudovibrio genomes. This gene cluster is also present in Pseudomonas bacteria that interact with terrestrial plants and animals. …”
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