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3901
The Legionella pneumophila effector PieF modulates mRNA stability through association with eukaryotic CCR4−NOT
Published 2025-01-01“…In mammalian cells, expression of PieF leads to a variety of quantifiable phenotypes: PieF silences gene expression and reduces mRNA steady-state levels when artificially tethered to a reporter transcript, and its overexpression results in the nuclear exclusion of CNOT7. PieF expression also disrupts the association between CNOT6/6L EEP-type nucleases and CNOT7. …”
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3902
Detection of CRISPR‒Cas and type I R–M systems in Klebsiella pneumoniae of human and animal origins and their relationship to antibiotic resistance and virulence
Published 2025-02-01“…In addition, this study also characterizes the CRISPR arrays of K. pneumoniae from different hosts, suggesting that the strains sharing the same spacer sequences have the potential to spread between humans and animals.…”
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3903
Targets of influenza human T-cell response are mostly conserved in H5N1
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3904
Structure and identification of the native PLP synthase complex from Methanosarcina acetivorans lysate
Published 2025-01-01“…This study demonstrates the potential of applying the cryoID workflow to capture native structural states at atomic resolution for archaeal systems, for which traditional biochemical sample preparation is nontrivial.IMPORTANCEArchaea are one of the three domains of life, classified as a phylogenetically distinct lineage. …”
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3905
Virulence profile of carbapenem-resistant Klebsiella pneumoniae strains by an in vivo model of Galleria mellonella
Published 2025-02-01“…ABSTRACT Klebsiella pneumoniae is a significant healthcare-associated pathogen, notable for its diverse virulence and antibiotic resistance profiles. This study aimed to characterize the genotypic and phenotypic diversity of K. pneumoniae isolates and evaluate their virulence using the Galleria mellonella model. …”
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3907
تحلیل و بررسی عوامل مؤثر بر توانمندی روانشناختی زعفران کاران روستایی با توجه به راهبردهای مدیریت ریسک محور تولید (مطالعه موردی: دهستان رشتخوار)...
Published 2021-05-01“…برای تجزیهوتحلیل دادهها نیز از ماتریس ذینفعان در مدل تلفیقی asm، نرمافزار SPSS و برای تحلیل فضایی از نرمافزارهای و Topsis- Fazi استفاده گردید. …”
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3909
RETRACTED: The Mechanism of Pertussis Cough Revealed by the Mouse-Coughing Model
Published 2022-04-01“…ABSTRACT Pertussis, also known as whooping cough, is a contagious respiratory disease caused by the Gram-negative bacterium Bordetella pertussis. …”
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3910
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3911
Phage-mediated virulence loss and antimicrobial susceptibility in carbapenem-resistant Klebsiella pneumoniae
Published 2025-02-01“…Evolved bacterial clones not only exhibited increased sensitivity to clinically important antibiotics but also displayed a loss of virulence in an in-vivo model. …”
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3912
Gcn2 rescues reprogramming in the absence of Hog1/p38 signaling in C. neoformans during thermal stress
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3913
Major facility superfamily sugar transporter protein SsMFSST1 regulates Sporisorium scitamineum mating, pathogenicity, and sugar transport/absorption
Published 2025-02-01“…The pathogenicity testing also found a significant decrease in the pathogenicity of combinations containing mutants. …”
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3914
Identification and characterization of Serratia nematophila and Acinetobacter guillouiae from putrid-skin disease lesions in farmed Chinese spiny frog (Quasipaa spinosa)
Published 2025-02-01“…ABSTRACT Serratia and Acinetobacter are recognized as significant opportunistic pathogens affecting aquatic animals and humans. However, their infections in amphibians are poorly documented, and their pathogenicity to the Chinese spiny frog (Quasipaa spinosa) remains unexplored. …”
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3915
The prebiotic potential of dietary onion extracts: shaping gut microbial structures and promoting beneficial metabolites
Published 2025-01-01“…The findings underscore the potential of onion extracts to improve gut health by enriching specific beneficial bacteria and metabolic pathways, thereby supporting the development of functional foods aimed at improving gut microbiota composition and metabolic health.…”
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3916
How does gut microbiota affect the vaginitis axis? The mediating role of plasma metabolites
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3917
Soil microbiome interventions for carbon sequestration and climate mitigation
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3918
Establishment and application of a rapid new detection method for antimicrobial susceptibility testing of Klebsiella pneumoniae based on MALDI-TOF MS
Published 2025-01-01“…The gold standard method of AST relies on visible bacterial growth, causing long turnaround times. …”
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3919
Non-lytic spread of poliovirus requires the nonstructural protein 3CD
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3920