Transendothelial migration of the Lyme disease spirochete involves spirochete internalization as an intermediate step through a transcellular pathway that involves Cdc42 and Rac1 by Daiana Alvarez-Olmedo, Claire Kamaliddin, Theodore B. Verhey, May Ho, Rebekah De Vinney, George Chaconas

“…Our new experimental system also provides a new avenue for further studies of this important process.…”
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Association between body composition indices and vascular health: a systematic review and meta-analysis by Mohammad Nikoohemmat, Amirhossein Ramezani Ahmadi, Ali Valizadeh, Seyed Mohammadmisagh Moteshakereh, Reza Yari-Boroujeni, Zahra Seifi, Majid Valizadeh, Behnaz Abiri

“…Subgroup analyses revealed a non-significant association between appendicular skeletal muscle (ASM) and IMT (ES: 1.01, 95% CI 0.76–1.35). Conclusion This meta-analysis highlights the complex relationship between body composition and vascular health. …”
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Genome evolution following an ecological shift in nectar-dwelling Acinetobacter by Vivianna A. Sanchez, Tanya Renner, Lydia J. Baker, Tory A. Hendry

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Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens by Karthik Hullahalli, Katherine G. Dailey, Ryan Acbay, Masataka Suzuki, George I. Balazs, Matthew K. Waldor

“…Since liver necrosis is linked to heightened systemic inflammatory responses, we hypothesized that NRTIs diminish inflammation caused by E. coli infection and may also have broad impacts on the systemic immune response to bacterial pathogens. …”
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Mass Transfer and Intrinsic Light Variability in the Contact Binary MT Cas by Haifeng Dai, Huiyu Yuan, Yuangui Yang

“…With Wilson-Devinney code, the photometric solutions are deduced from VRc light curves (LCs) and AAVSO’s and ASAS-SN’s data, respectively. The results imply that MT Cas is a W-type weak-contact binary with a mass ratio of q=2.365(±0.005) and a fill-out factor of f=16.6(±1.2)%, respectively. …”
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Anticorrelations between Active Brain Regions: An Agent-Based Model Simulation Study by Fabrizio Parente, Alfredo Colosimo

“…A large-scale brain representation was considered, implementing an agent-based brain-inspired model (ABBM) incorporating the SER (susceptible-excited-refractory) cyclic mechanism of state change. …”
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ANCA-Associated Vasculitides and Hematologic Malignancies: Lessons from the Past and Future Perspectives by Marco Folci, Giacomo Ramponi, Dana Shiffer, Aurora Zumbo, Michele Agosti, Enrico Brunetta

“…PR3-derived PR1 peptide is being studied as an immunotherapy target in leukemia and multiple myeloma. This study is aimed at bringing together various evidences from the field of immunological and hematological research, at exposing contradictions, and at revealing novel insights on the association between ANCA-associated vasculitis and hematologic malignancies.…”
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Whole-genome phylogenetic analysis of Mycobacterium avium complex from clinical respiratory samples by Chew Ka Lip, Joelle Go, Nur Aisyah Binte Abu Bakar, Sophie Octavia, Raymond Tzer Pin Lin, Jeanette W. P. Teo

“…ABSTRACT The Mycobacterium avium complex (MAC) is a common causative agent causing nontuberculous mycobacterial (NTM) pulmonary disease worldwide. …”
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Pulmonary granuloma formation during latent Cryptococcus neoformans infection in C3HeB/FeJ mice involves progression through three immunological phases by Jovany J. Betancourt, Minna Ding, J. Marina Yoder, Issa Mutyaba, Hannah M. Atkins, Gabriela De la Cruz, David B. Meya, Kirsten Nielsen

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The Rickettsia actin-based motility effectors RickA and Sca2 contribute differently to cell-to-cell spread and pathogenicity by Cuong J. Tran, Zahra Zubair-Nizami, Ingeborg M. Langohr, Matthew D. Welch

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Comparison of positive BioFire FilmArray meningitis/encephalitis (ME) panels, CSF cultures, CSF parameters, clinical presentation and in-patient mortality among patients with bacte... by Thein Myint, Jaime Soria, Yuanzheng Gao, Marice Ruiz Conejo Castillo, Vaneet Arora, Julie A. Ribes

“…This study highlights the utility of MEP in rapidly diagnosing ME, particularly in patients pretreated with antibiotics. It also emphasizes the importance of correlating MEP results with clinical assessments and other diagnostic tests to assure accuracy.IMPORTANCEThis study compares the performance of the meningitis/encephalitis panel (MEP) in detecting bacterial and fungal pathogens with cerebrospinal fluid cultures and other parameters. …”
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Evaluating the feasibility, sensitivity, and specificity of next-generation molecular methods for pleural infection diagnosis by Peter T. Bell, Timothy Baird, John Goddard, Olusola S. Olagoke, Andrew Burke, Shradha Subedi, Tiana R. Davey, James Anderson, Derek S. Sarovich, Erin P. Price

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The influence of environmental factors on the detection and quantification of SARS-CoV-2 variants in dormitory wastewater at a primarily undergraduate institution by Chequita Brooks, Sebrina Brooks, Josie Beasley, Jenna Valley, Michael Opata, Ece Karatan, Rachel Bleich

“…We consistently quantified a significantly higher number of copies of virus per liter for the target nucleocapsid 2 (N2) compared to nucleocapsid 1 (N1), regardless of the sampling method (grab vs composite). We further show some dormitory-specific differences in SARS-CoV-2 abundance, including correlations to dormitory population size. …”
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Genetic profiling of multidrug-resistant Acinetobacter baumannii from a tertiary care center in Malaysia by Aisyah Syakirah Shahari, Navindra Kumari Palanisamy, Fadzilah Mohd Nor

“…The antibiotic resistance genes blaOXA-23, blaVIM, and blaADC were detected in both chromosomal and plasmid DNA. …”
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A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction by Nathan P. Crilly, Marcelle Dina Zita, Alexander K. Beaver, Polina Sysa-Shah, Aashik Bhalodia, Kathy Gabrielson, Luigi Adamo, Monica R. Mugnier

“…ABSTRACT Trypanosoma brucei is a protozoan parasite that causes human and animal African trypanosomiases (HAT and AAT). Cardiac symptoms are commonly reported in HAT patients, and intracardiac parasites with accompanying myocarditis have been observed in both natural hosts and animal models of T. brucei infection. …”
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Strawberry dietary intervention influences diversity and increases abundances of SCFA-producing bacteria in healthy elderly people by Franziska Meiners, Bernd Kreikemeyer, Patrick Newels, Ingmar Zude, Michael Walter, Alexander Hartmann, Daniel Palmer, Georg Fuellen, Israel Barrantes

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Identification of novel fructo-oligosaccharide bacterial consumers by pulse metatranscriptomics in a human stool sample by Catherine Prattico, Emmanuel Gonzalez, Lharbi Dridi, Shiva Jazestani, Kristin E. Low, D. Wade Abbott, Corinne F. Maurice, Bastien Castagner

“…Our approach can be applied to identify consumers of understudied glycans and expand our prebiotic repertoire. It can also be used to study prebiotic glycans directly in stool samples in distinct patient populations to help delineate the prebiotic mechanism.…”
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Characterization of Enterobacterales growing on selective CPE screening plates with a focus on non-carbapenemase-producing strains by Reut Efrati Epchtien, Elizabeth Temkin, Mor N. Lurie-Weinberger, Ophir Kastel, Alona Keren-Paz, David Schwartz, Yehuda Carmeli

“…The population of non-CPE growing on CPE selective plates during routine screening is usually not reported and is not well defined. This study aimed to characterize non-CPE isolates growing on those plates. …”
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Human adenovirus species B knob proteins as immunogens for inducing cross-neutralizing antibody responses by Zhenwei Liu, Yuting Xian, Jixian Lan, Zhichao Zhou, Xiao Li, Rong Zhou, Dehui Chen, Xingui Tian

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