Fetal Cartilage Progenitor Cells in the Repair of Osteochondral Defects by Bruno C. Menarim, DVM, PhD, Chan Hee Mok, PhD, Kirsten E. Scoggin, PhD, Alexis Gornik, DVM, Emma N. Adam, DVM, PhD, Shavahn C. Loux, PhD, James N. MacLeod, VMD, PhD

“…Studies grafting IZN or ANL tissues in larger animal models with regular immune functions may provide additional insights into improving osteochondral regeneration.…”
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Clinical, pathological, and genotypic analysis of infectious bronchitis virus in broiler chickens in the Abu Dhabi Emirate, United Arab Emirates by Hassan Zackaria Ali Ishag, Abdelnasir Mohammed Adam Terab, Ebrahim Mohamad Abdalsalam Osman, El Tigani Ahmed El Tigani-Asil, El Tigani Ahmed El Tigani-Asil, Mohammed Saleh Albreiki, Oum Keltoum Bensalah, Asma Abdi Mohamed Shah, Abdelmalik Ibrahim Khalafalla

“…Despite vaccination efforts in poultry farms in the Abu Dhabi Emirate, United Arab Emirates (UAE), outbreaks continue to occur, raising concerns about the efficacy of vaccination protocols and the potential emergence of new viral strains. This study aims to provide information on clinical, pathological, and genotypes of IBV detected within the Abu Dhabi Emirate, during 2022–2023.MethodsEpidemiological data were collected from twelve suspected IB outbreaks across seven broiler farms located in the Abu Dhabi Emirate. …”
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Dendritic excitations govern back-propagation via a spike-rate accelerometer by Pojeong Park, J. David Wong-Campos, Daniel G. Itkis, Byung Hun Lee, Yitong Qi, Hunter C. Davis, Benjamin Antin, Amol Pasarkar, Jonathan B. Grimm, Sarah E. Plutkis, Katie L. Holland, Liam Paninski, Luke D. Lavis, Adam E. Cohen

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Cucumeropsis mannii seed oil shields against cyclophosphamide-induced hepatorenal toxicity by modulating redox imbalance and iNOS/IL-β1 signalling in rats by Amaka Cecilia Agbara, Ejike Daniel Eze, Christian Emeka Offor, Adam Moyosore Afodun, Ezebuilo Ugbala Ekpono, Peter Chinedu Agu, Chinyere Aloke, Nkeiru Nwaamaka Ezeani, Emmanuel Orire Ikuomola, Ekom Monday Etukudo, Ilemobayo Victor Fasogbon, Angela Mumbua Musyoka, Patrick Maduabuchi Aja

“…This study aimed to determine whether C. mannii seed oil (CMSO) could shield rats from cyclophosphamide-induced hepatorenal toxicity. …”
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Ultra high density imaging arrays in diffuse optical tomography for human brain mapping improve image quality and decoding performance by Zachary E. Markow, Jason W. Trobaugh, Edward J. Richter, Kalyan Tripathy, Sean M. Rafferty, Alexandra M. Svoboda, Mariel L. Schroeder, Tracy M. Burns-Yocum, Karla M. Bergonzi, Mark A. Chevillet, Emily M. Mugler, Adam T. Eggebrecht, Joseph P. Culver

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Outcomes of anterior cruciate ligament reconstruction surgery from private and public healthcare services in AustraliaKey points by Thomas J. West, Andrea M. Bruder, Kay M. Crossley, Michael A. Girdwood, Laura K. To, Jamon L. Couch, Mark J. Scholes, Sebastian C.S. Evans, Melissa J. Haberfield, Christian J. Barton, Ewa M. Roos, Alysha De Livera, Adam G. Culvenor

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Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions. by Karen Campos-León, Jack Ferguson, Thomas Günther, C David Wood, Steven W Wingett, Selin Pekel, Christy S Varghese, Leanne S Jones, Joanne D Stockton, Csilla Várnai, Michelle J West, Andrew Beggs, Adam Grundhoff, Boris Noyvert, Sally Roberts, Joanna L Parish

“…Since CTCF is an important regulator of host cell transcription via coordination of epigenetic boundaries and long-range chromosomal interactions, we hypothesised that HPV18 may also manipulate CTCF to contribute to host transcription reprogramming. …”
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An ontology-based rare disease common data model harmonising international registries, FHIR, and Phenopackets by Adam S. L. Graefe, Miriam R. Hübner, Filip Rehburg, Steffen Sander, Sophie A. I. Klopfenstein, Samer Alkarkoukly, Ana Grönke, Annic Weyersberg, Daniel Danis, Jana Zschüntzsch, Elisabeth F. Nyoungui, Susanna Wiegand, Peter Kühnen, Peter N. Robinson, Oya Beyan, Sylvia Thun

“…Abstract Although rare diseases (RDs) affect over 260 million individuals worldwide, low data quality and scarcity challenge effective care and research. This work aims to harmonise the Common Data Set by European Rare Disease Registry Infrastructure, Health Level 7 Fast Healthcare Interoperability Base Resources, and the Global Alliance for Genomics and Health Phenopacket Schema into a novel rare disease common data model (RD-CDM), laying the foundation for developing international RD-CDMs aligned with these data standards. …”
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Diagnostic accuracy of calculated serum osmolarity to predict dehydration in older people: adding value to pathology laboratory reports by Lee Shepstone, John F Potter, Lee Hooper, Asmaa Abdelhamid, Amy Jennings, Paul R Hunter, W Garry John, Neil P Walsh, Adam Ali, Diane K Bunn, Susan Kerry, Gregor Lindner, Carmen A Pfortmueller, Fredrik Sjöstrand, Susan J Fairweather-Tait

“…Objectives To assess which osmolarity equation best predicts directly measured serum/plasma osmolality and whether its use could add value to routine blood test results through screening for dehydration in older people.Design Diagnostic accuracy study.Participants Older people (≥65 years) in 5 cohorts: Dietary Strategies for Healthy Ageing in Europe (NU-AGE, living in the community), Dehydration Recognition In our Elders (DRIE, living in residential care), Fortes (admitted to acute medical care), Sjöstrand (emergency room) or Pfortmueller cohorts (hospitalised with liver cirrhosis).Reference standard for hydration status Directly measured serum/plasma osmolality: current dehydration (serum osmolality >300 mOsm/kg), impending/current dehydration (≥295 mOsm/kg).Index tests 39 osmolarity equations calculated using serum indices from the same blood draw as directly measured osmolality.Results Across 5 cohorts 595 older people were included, of whom 19% were dehydrated (directly measured osmolality >300 mOsm/kg). …”
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Epidemiology and diversity of Plasmodium species in Franceville and their implications for malaria control by Larson Boundenga, Yann Vital Sima-Biyang, Neil Michel Longo-Pendy, Michelle Bignoumba, Clark Mbou-Boutambe, Clauve Jauvert Moukagni-Mussadji, Dorothé Marielle Wora, Fabrice Kassa-Kassa, Richard Onanga, Cyrille Bisseye, Francine Ntoumi, Ayola Akim Adegnika, Jean-Bernard Lekana-Douki

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The PRC2.1 subcomplex opposes G1 progression through regulation of CCND1 and CCND2 by Adam D Longhurst, Kyle Wang, Harsha Garadi Suresh, Mythili Ketavarapu, Henry N Ward, Ian R Jones, Vivek Narayan, Frances V Hundley, Arshia Zernab Hassan, Charles Boone, Chad L Myers, Yin Shen, Vijay Ramani, Brenda J Andrews, David P Toczyski

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Activation of three targets by a TAL effector confers susceptibility to bacterial blight of cotton by Brendan W. Mormile, Yan Yan, Taran Bauer, Li Wang, Rachel C. Rivero, Sara C. D. Carpenter, Catherine Danmaigona Clement, Kevin L. Cox, Lin Zhang, Xiyu Ma, Terry A. Wheeler, Jane K. Dever, Ping He, Adam J. Bogdanove, Libo Shan

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Impact of smartphone addiction on health status, mental well-being, and sleep quality among medical students in Sudan by Mohammed Hammad Jaber Amin, Hadia Abdelbagi Alhadi, Asma Eltayeb Abdalla Mohamed, Hiba Kamal Eldin Taha Yacoub, Rabeia MohammedAhmed Hassan Khalifa, Ibrahim Abusufian Elkabashi Dafallah, Fatima Mohamed Osman Yasin, Amira Mohamed Taha, Mohammed Yousif Abdalla Adam, Majdy Osama Abualabasher

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Cellular rejuvenation protects neurons from inflammation-mediated cell death by Sienna S. Drake, Abdulshakour Mohammadnia, Aliyah Zaman, Christine Gianfelice, Kali Heale, Adam M.R. Groh, Elizabeth M.-L. Hua, Matthew A. Hintermayer, Yuancheng Ryan Lu, David Gosselin, Stephanie Zandee, Alexandre Prat, Jo Anne Stratton, David A. Sinclair, Alyson E. Fournier

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Prevalence of depression and its correlates among undergraduate health science students in Mogadishu, Somalia: a cross-sectional study by Bashiru Garba, Samiro Ali Mohamed, Maria Mowlid Mohamed, Hodo Aideed Asowe, Najib Isse Dirie, Yushau Umar, Jamal Hassan Mohamoud, Mohamed Hussein Adam, Jihaan Hassan, Fartun Abdullahi Hassan Orey, Abdullahi Abdirahman Omar, Ibrahim Abdullahi Mohamed, Mohamad Mustaf Ahmed, Samira Abdullahi Moalim

“…Similarly, gender of students was also found to be statistically significant (p-value = 0.001) with female students having 65% depression which is 41.1% of the total students studied. …”
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Transfusion Related Acute Lung Injury (TRALI) Caused by Red Blood Cell Transfusion Involving Residual Plasma Anti-HLA Antibodies: A report on two Cases and General Considerations by Olivier Garraud, Léna Absi, Danielle Rebibo, Jean-Yves Muller, Patricia Fromont, Evelyne Voitellier, Marie-Françoise Raynal, Philippe Verdier, Soizick Ducroz, Pascale Ruyer-Dumontier, Fabienne Quainon, Hélène Odent-Malaure

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TOURISM study (Treatment Outcomes in UteRIne SarcoMa): a 10-year retrospective evaluation of practice in the UK by Rebekah Webb, Mohammed Al-Zubaidi, Mark A Baxter, Karin Purshouse, James Robertson, Helen Creedon, Katherine Fair, Asma Sarwar, Laura Hannington, Adam L Peters, Samuel Mcinerney, Karen E Mactier, Georgina E Wood, Mai K Bishr, Leonie Eastlake, Katharine Lankester, Alison L Stillie

“…Treatment options and robust trial data are limited.Objectives The TOURISM study (Treatment Outcomes in UteRIne SarcoMa) is a UK-wide study by the National Oncology Trainees Collaborative for Healthcare Research which aimed to characterise this patient cohort.Design A retrospective descriptive cohort study. …”
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Prevalence of Antimicrobial-Resistant Pathogens in Canadian Hospitals: Results of the Canadian Ward Surveillance Study (CANWARD 2007) by George G Zhanel, James A Karlowsky, Mel DeCorby, Kim A Nichol, Aleksandra Wierzbowski, Patricia J Baudry, Philippe Lagacé-Wiens, Andrew Walkty, Frank Schweizer, Heather Adam, Melissa McCracken, Michael R Mulvey, The Canadian Antimicrobial Resistance Alliance (CARA), Daryl J Hoban

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Assessment of targets of antibody drug conjugates in SCLC by Abhishek Ajay, Han Wang, Ali Rezvani, Omid Savari, Brandon J. Grubb, Karen S. McColl, Suzy Yoon, Peronne L. Joseph, Shelby R. Kopp, Adam M. Kresak, Craig D. Peacock, Gary M. Wildey, Minh Lam, Masaru Miyagi, Hung-Ying Kao, Afshin Dowlati

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Development of a territory-wide household-based composite index for measuring relative distribution of households by economic status in individual small areas throughout Hong Kong by Eva L.H. Tsui, Philip L.H. Yu, K. F. Lam, Kelvin K.Y. Poon, Adam C.M. Ng, K. Y. Cheung, Winnie Li, Michael L.H. Leung, David H.Y. Lam, James L.Y. Cheng, Sharon P.W. Ng

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