ATP-binding cassette transporters and drug resistance in cutaneous leishmaniasis by Marina B.R. de Santana, Giulia O. Miranda, Lucas P. Carvalho

“…Many factors can influence leishmaniasis treatment outcome, including low expression aquaglyceroporin by the parasite and high activity of the ATP-binding cassette (ABC) transporters, efflux pumps whose activity has been associated with drug resistance in a variety of diseases. …”
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"Energetics of the outer retina I: Estimates of nutrient exchange and ATP generation". by Stella Prins, Christina Kiel, Alexander J E Foss, Moussa A Zouache, Philip J Luthert

“…Photoreceptors (PRs) are metabolically demanding and packed at high density, which presents a challenge for nutrient exchange between the associated vascular beds and the tissue. …”
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S-DCNN: prediction of ATP binding residues by deep convolutional neural network based on SMOTE by Sixi Hao, Sixi Hao, Cai-Yan Li, Xiuzhen Hu, Zhenxing Feng, Gaimei Zhang, Caiyun Yang, Huimin Hu

“…Currently, the precise prediction of ATP binding residues remains challenging.MethodsBased on the sequence information, this paper introduces a method called S-DCNN for predicting ATP binding residues, utilizing a deep convolutional neural network (DCNN) enhanced with the synthetic minority over-sampling technique (SMOTE).ResultsThe incorporation of additional feature parameters such as dihedral angles, energy, and propensity factors into the standard parameter set resulted in a significant enhancement in prediction accuracy on the ATP-289 dataset. …”
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Identification of CTL Epitopes on Efflux Pumps of the ATP-Binding Cassette and the Major Facilitator Superfamily of Mycobacterium tuberculosis by Yan Lin, Yu Dong, Yanfeng Gao, Ranran Shi, Yubing Li, Xiuman Zhou, Wenwen Liu, Guodong Li, Yuanming Qi, Yahong Wu

“…In this study, we identified cytotoxic T lymphocyte epitopes on drug resistance-associated membrane protein efflux pumps of MTB, the ATP-binding cassette and the major facilitator superfamilies. …”
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The Wilson's disease - etiology, symptoms in various organs, diagnosis, treatment, prognosis by Patryk Graczyk, Paulina Klaudia Kwaśniewska, Anna Wilewska, Kinga Borowiec, Agnieszka Borowiec, Julia Biernikiewicz, Konstanty Alabrudziński, Milena Biernikiewicz, Bartosz Pomirski, Agata Pomirska

“…Introduction: Wilson disease (WD) is a genetic disorder of copper metabolism caused by ATP7B gene mutations, impairing copper excretion and leading to copper accumulation in organs. …”
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Predicting hepatocellular carcinoma outcomes and immune therapy response with ATP-dependent chromatin remodeling-related genes, highlighting MORF4L1 as a promising target by Chao Xu, Litao Liang, Guoqing Liu, Yanzhi Feng, Bin Xu, Deming Zhu, Wenbo Jia, Jinyi Wang, Wenhu Zhao, Xiangyu Ling, Yongping Zhou, Wenzhou Ding, Lianbao Kong

“…Recent research has identified ATP-dependent chromatin remodeling-related genes (ACRRGs) as promising targets for therapeutic intervention across various types of cancer. …”
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Inhibiting ATP6V0D2 Aggravates Liver Ischemia-Reperfusion Injury by Promoting NLRP3 Activation via Impairing Autophagic Flux Independent of Notch1/Hes1 by Ziyi Wang, Hao Wang, Xuejiao Chen, Sheng Han, Yulin Zhu, Hanhua Wang, Feng Cheng, Liyong Pu

“…At present, liver ischemia-reperfusion (IR) injury is still a great challenge for clinical liver partial resection and liver transplantation. …”
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Pharmacological Characterization of the Mechanisms Involved in Delayed Calcium Deregulation in SH-SY5Y Cells Challenged with Methadone by Sergio Perez-Alvarez, Maria E. Solesio, Maria D. Cuenca-Lopez, Raquel M. Melero-Fernández de Mera, Carlos Villalobos, Hanna Kmita, Maria F. Galindo, Joaquin Jordán

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Gender difference in metabolic syndrome and quality of life among elderly people in Noakhali, Bangladesh by Marjia Sultana, Md. Mehedi Hasan, Towhid Hasan

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On Typical Flaws of the Transformer Models for Inrush Current Evaluation by Serhii Zirka, Yurii Moroz

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Exploring the Prevalence and Components of Metabolic Syndrome in Sub-Saharan African Type 2 Diabetes Mellitus Patients: A Systematic Review and Meta-Analysis by Nelson Musilanga, Hussein Nasib, Given Jackson, Frank Shayo, Clarkson Nhanga, Saleh Girukwigomba, Ambokile Mwakibolwa, Samson Henry, Keneth Kijusya, Edgar Msonge

“…Central obesity was the most prevalent component of metabolic syndrome, with a pooled prevalence of 55.9% and 61.6% using NCEP-ATP III 2004 and IDF criteria, respectively. There was no statistical evidence of publication bias in both the NCEP-ATP III 2004 and IDF pooled estimates. …”
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Gelatin/Poly (Lactic-Co-Glycolic Acid)/Attapulgite Composite Scaffold Equipped with Teriparatide Microspheres for Osteogenesis in vitro and in vivo by Zhao Z, Feng X, Zhao Y, Song Z, Zhang R, Zhang K, He Y, Chen G, Zhang J, Wang W

“…Teriparatide (TPTD) plays a significant role in bone defect repair, although achieving controlled release of TPTD within a bone tissue engineering scaffold remains challenging. This work reports a new approach for treatment of teriparatide using a water-in-oil-in-water (w/o/w) microspheres be equipped on gelatin (GEL)/Poly lactic-glycolic acid (PLGA)/attapulgite (ATP) scaffold.Methods: In this study, TPTD microspheres were prepared by the water-in-oil-in-water (w/o/w) double emulsion technique and GEL/PLGA/ATP composite scaffolds with different setups were prepared by salt leaching method. …”
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Resveratrol-loaded metal-organic framework for mitochondria-targeted amplified CO gas therapy by Fengqin Wang, Yinfang Jiang, Yang Wang

“…However, the primary challenge in gas therapy is the effective delivery of gas prodrug to targeted sites, as well as achieving precise spatial-temporal control over their release behavior. …”
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Comparative genomics of large mitochondria in placozoans. by Ana Y Signorovitch, Leo W Buss, Stephen L Dellaporta

“…They share with the Trichoplax mitochondrial genome the absence of atp8, atp9, and all ribosomal protein genes, the presence of several cox1 introns, and a large open reading frame containing an intron group I LAGLIDADG endonuclease domain. …”
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Resveratrol Alleviates NEFA-Induced Oxidative Damage in Bovine Mammary Epithelial Cells by Restoring Mitochondrial Function by Longwei Sun, Junpeng Huang, Xiangyang Dou, Zhenyu Dong, Yuan Li, Shujing Tan, Ran Yu, Chengmin Li, Weiguo Zhao

“…RES treatment restored mitochondrial function in NEFA-stressed BMECs, as evidenced by the increase in MMP, ATP generation and NAD⁺/NADH ratio accompanying the decline in mitochondrial structural abnormalities and cell apoptosis. …”
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Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation by Adam Aguirre, Carola J. Maturana, Paloma A. Harcha, Juan C. Sáez

“…Consequently, activated microglia and astrocytes release ATP and glutamate, affecting myelinization, neuronal development, and survival. …”
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Endothelial Cells Potentially Participate in the Metastasis of Triple-Negative Breast Cancer by Yanfei Ma, Yanghong Li, Pengwei Guo, Jingjie Zhao, Qiang Qin, Jiajia Wang, Zhengfang Liang, Dalong Wei, Zechen Wang, Jiajia Shen, Siyuan He, Qianli Tang, Guanming Lu, Guiling Shi, Lingzhang Meng

“…Inhibition of triple-negative breast cancer metastasis has long been a challenge, mainly due to the difficulty in identifying factors that contribute to this process. …”
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Mitochondrial DNA copy number as a mediator of the relationship between insulin resistance and cognitive function in patients with euthymic bipolar disorder by Tsung Han Tsai, Cheng Ying Wu, Cheng Chen Chang, Ta Tsung Lin, Chin San Liu, Po See Chen

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Pyrroloquinoline Quinone Improved Boar Sperm Quality via Maintaining Mitochondrial Function During Cryopreservation by Shanpeng Wang, Qi Wang, Lingjiang Min, Hailiang Cao, Adedeji O. Adetunji, Kaifeng Zhou, Zhendong Zhu

“…Additionally, 1000 nM PQQ increased mitochondrial membrane potential (MMP) and ATP levels, while decreasing MDA and mitochondrial ROS levels, and reducing DNA damage (<i>p</i> < 0.05). …”
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Management of Neonatal Diabetes due to a KCNJ11 Mutation with Automated Insulin Delivery System and Remote Patient Monitoring by Ming Yeh Lee, Anna L. Gloyn, David M. Maahs, Priya Prahalad

“…Management of hyperglycemia in neonates with subcutaneous insulin is challenging because of frequent feeding, variable quantity of milk intake with each feed, low insulin dose requirements, and high risk for hypoglycemia and associated complications in this population. …”
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