Breaking the shield of solid tumors: a combined approach for enhanced efficacy of CAR-T cells by Marat Khaliulin, Aygul Valiullina, Alexey Petukhov, Youyong Yuan, Sheila Spada, Emil Bulatov

“…Solid tumors exhibit antigenic diversity and an immunosuppressive microenvironment, which presents a challenge for immune cells attempting to penetrate the tumor. CAR-T cells also demonstrate decreased proliferative activity and cytotoxicity. …”
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Chronic Central Serous Chorioretinopathy in a Patient with Pigment Dispersion Syndrome: A Possible Correlation by Dimitrios Kourkoutas, George Tsakonas, Aristotelis Karamaounas, Nikolaos Karamaounas

“…Chronic central serous chorioretinopathy (CSCR) is a progressive chorioretinopathy with widespread atrophic RPE abnormalities and serous retinal detachments (SRDs) present for 6 months or longer. …”
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Eosinofilik Esofagitis by Yusri Dianne Jurnalis, Yorva Sayoeti, Widiasteti Widiasteti

“…<br />Keywords:Eosinophilic esophagitis, food allergy, atopy</p>…”
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Progenitor Cell Therapy to Treat Acute Myocardial Infarction: The Promise of High-Dose Autologous CD34+ Bone Marrow Mononuclear Cells by Joseph C. Poole, Arshed A. Quyyumi

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The Relationships between Parental Involvement, Students’ Basic Psychological Needs and Students’ Engagement in Science: A Path Analysis by Uluhan Kurt, Yasemin Tas

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Pandangan fiqh siyasah terhadap penyelewengan fasilitas hotel syariah menjadi tempat tindak prostitusi by Muhammad Fawwaz Salim, Irwansyah Irwansyah

“…Prostitusi suatu pekerjaan yang bersifat menyerahkan diri atau menjual jasa kepada umum untuk melakukan perbuatan-perbuatan seksual dengan mendapatkan upah sesuai dengan apa yang di perjanjikan sebelumnya. …”
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Coronary Heart Disease in Postmenopausal Women with Type II Diabetes Mellitus and the Impact of Estrogen Replacement Therapy: A Narrative Review by Marouane Boukhris, Salvatore Davide Tomasello, Francesco Marzà, Sonia Bregante, Francesca Romana Pluchinotta, Alfredo Ruggero Galassi

“…It was established that the deficiency of endogenous estrogens promotes the atherosclerosis process. However, the impact of estrogen replacement therapy (ERT) on cardiovascular prevention remains controversial. …”
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Impact of Local Soil Conditions on Earthquake Sensitivity in Erzincan City by Emre Özşahin, İlker Eroğlu

“…The most sensitive districts to earthquake are Atatürk, İnönü, Karaağaç, Kızılay, and Yenimahalle. …”
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Infantile epileptic spasms syndrome: an etiologic study of 361 patients with infantile epileptic spasms syndrome by Linghui Zhu, Linghui Zhu, Yuan Xia, Yuan Xia, Hao Ding, Tong Zhang, Jun Li, Baomin Li, Baomin Li

“…Patients administered adrenocorticotropic hormone (ACTH) exhibited a higher likelihood of attaining seizure control, and those who responded favorably to the medication saw improved results.ConclusionThe predominant etiology of IESS is structural, succeeded by genetic factors, with significant pathogenic genes comprising TSC2, NF1, SCN8A, and KCNQ2. …”
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Temporal and Spatial Evolution Characteristics of Extreme Climate Events in Grand Shangri-La Region from 1961 to 2019 by WU Yang, JIN Hanyu, CHENG Qingping

“…The Grand Shangri-La region connects the Qinghai-Tibet Plateau,the Yunnan-Guizhou Plateau,and the Hengduan Mountains and is of great geographical significance.Five rivers flow through the region,and the climate is vulnerable.Therefore,it is necessary to explore extreme climate changes and their response mechanism,so as to assess regional climate risks and achieve disaster warnings.Based on the daily temperature and precipitation data of 56 meteorological stations from 1961 to 2019,this paper analyzes changes in extreme climate indexes and their correlation with large-scale circulation index in the region by using Mann-Kendall,Sen's slope estimation,Pettitt test,and Pearson correlation analysis.The results show that:① The extreme warm index and the extreme precipitation intensity index (RX1day,R95p,R99p,and SDII) increase significantly,while the cold index (CSDI、FD、ID、TN10p、TX10p) and the number of continuous humid days decrease greatly.In terms of different seasons,the warming amplitude of most of the extreme temperature indexes in winter is higher than that in summer,and the precipitation intensity increases gradually in summer and autumn but decreases slightly in winter.② Spatially,the diurnal temperature range in the north of the Qinghai-Tibet Plateau is higher than that in the south,and the frequency of extremely high-temperature rises,with the high temperature appearing mostly in arid valleys in the south and east of the Qinghai-Tibet Plateau.The precipitation intensity is high in the south and west of the Hengduan Mountains,and persistent precipitation is strong in the Yalong River basin and the upper reaches of the Jinsha River in the north.③ Extreme climate indexes and south China sea summer monsoon index (SCSMI) are significantly correlated in the same year.In addition,there is a one-year response lag between the extreme precipitation index and Arctic oscillation (AO),North Atlantic oscillation (NAO),and Pacific decadal oscillation (PDO).The above analysis shows that the Grand Shangri-La region generally shows warming and humid climate characteristics.The frequency of heavy precipitation in flood season and warm winter events increases and is closely related to large-scale circulation.…”
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On Some Numerical Radius Inequalities Involving Generalized Aluthge Transform by Javariya Hyder, Muhammad Saeed Akram, Abdulaziz S. Alofi, Dilruba Akter

“…In this paper, we present some numerical radius inequalities involving the generalized Aluthge transform to attain upper bounds for numerical radius. Numerical computations are carried out for some particular cases of generalized Aluthge transform.…”
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IMPLANTAÇÃO DO PLANO MUNICIPAL DE RESÍDUOS SÓLIDOS NAS CAPITAIS NORDESTINAS by Helano Diógenes Pinheiro, Elaine Maria Nazaré de Lima

“…Porém, em termos sistêmicos, a implantação dos planos municipais ainda são incipientes, considerando-se o baixo grau de reaproveitamento e reciclagem e a articulação dos atores. …”
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‘Thou Whole Burnt-Offering!’ The Mystical Ecstasy in Christina Rossetti’s Poems by Bertrand Lentsch

“…However unassuming she then appears to be, such moments of great feeling are her delightful way of atoning for her sins.…”
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CONTEXTUALISING URBAN ENGINEERING EDUCATION FOR FUTURE CITIES by Dillip K DAS, Fidelis EMUZE

“…This phenomenon necessitates a change in societal attitude in f avor of the creation of responsible living conditions, which demands requisite skills and knowledge that would shape the cities. …”
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Specific Surface Area Enhancement of Waste Tire-Based Activated Carbon by Demineralization Technique and Adsorption of Methylene Blue by Estifanos Kassahun, Sintayehu Mekuria, Surafel Mustefa Beyan

“…Maximum MB removal (89.41%) was attained at an impregnation ratio value of 0. A maximum yield (42.65%) was found at 48 h. …”
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A Novel Ultrasound Thermometry Method Based on Thermal Strain and Short and Constant Acoustic Bursts: Preliminary Study in Phantoms by Omar Gachouch, Bruno Giammarinaro, Teymour Kangot, Caterina Monini, Rémi Souchon

“…Under the assumption that the acoustic attenuation does not change significantly with temperature, the thermal strain induced by such bursts presents a linear relation with temperature. …”
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Similar Conditions With Opposite Effects: Predation‐Risk Effects on Prey Abundance Are Highly Contingent by Scott D. Peacor, Clayton E. Cressler, Kevin L. Pangle, Alexandra V. Rafalski, Chao Song, Earl E. Werner

“…Any differences in the experiments would typically be deemed incidental, that is, they would not be given attention in methodology, nor be presented as factors affecting results or inferences. …”
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STeInFormer: Spatial&#x2013;Temporal Interaction Transformer Architecture for Remote Sensing Change Detection by Xiaowen Ma, Zhenkai Wu, Mengting Ma, Mengjiao Zhao, Fan Yang, Zhenhong Du, Wei Zhang

“…Convolutional neural networks and attention mechanisms have greatly benefited remote sensing change detection (RSCD) because of their outstanding discriminative ability. …”
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The Effect of Health Anxiety on Subjective Happiness: Does Optimism Play a Protective Role? by Feridun Kaya, Gulin Yazici-Celebi, Muge Yilmaz

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Co-occurring factors associated with suicidal ideation among individuals with parole involvement: A classification and regression tree analysis by Leah MCCOY, Javier F. BOYAS, Sung Seek MOON, Michael A. ROBINSON, Onick LEWIS, Amy E. COX

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