Impact of duration of treatments with metformin and sulfonylureas, individually or in combination, on diabetic retinopathy among newly diagnosed type 2 diabetic patients: a pooled... by Mansour Bahardoust, Yadollah Mehrabi, Farzad Hadaegh, Davood Khalili, Ali Delpisheh

“…Methods The data of 4,068 newly diagnosed DM individuals(mean age, 60.2 ± 0.85 years) from three prospective cohorts of Tehran Sugar and Lipid Study (TLGS), Multi-Ethnic Study of Atherosclerosis (MESA), and Atherosclerosis Risk in Communities (ARIC) with a mean age of 59.6 ± 08 years were pooled. …”
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Robust Identification of Vegetation Change Using Shapelet-Based Temporal Segmentation of Landsat Time-Series Stacks: A Case Study in the Qilian Mountains by Lipeng Jiao, Randolph H. Wynne

“…Then, an iterative shapelet searching algorithm is performed on each given time series trajectory to filter out all atypical subseries. Finally, a multiple-spectral-index-based thresholding method is developed to measure the difference in spectral indices' statistical values between atypical and typical (stable) subseries. …”
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Dietary Histidine Supplementation Maintained Amino Acid Homeostasis and Reduced Hepatic Lipid Accumulation of Juvenile Largemouth Bass, Micropterus Salmoides by Hualiang Liang, Gangchun Xu, Pao Xu, Jian Zhu, Songlin Li, Mingchun Ren

“…Meanwhile, dietary histidine levels could be sensed by the AAR signaling pathway, representing as downregulation of core genes of AAR signaling pathway with the increased dietary histidine levels, including GCN2, eIF2α, CHOP, ATF4, and REDD1. In addition, increased dietary histidine levels decreased the lipid content of the whole body and the liver by upregulating the mRNA levels of core genes of the PPARα signaling pathways, including PPARα, CPT1, L-FABP, and PGC1α. …”
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Processo de profissionalização docente: o contexto das práticas by Carla Patrícia Acioli Lins

“…O exame das práticas dos professores destaca que planejar, desenvolver a aula, avaliar e mobilizar aprendizagens integram um único processo, racional e complexo, que compõe sua expertise, sendo a delimitação da atividade e definição da expertise importantes para a profissionalização docente. …”
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Microenvironment Influences on Human Umbilical Cord Mesenchymal Stem Cell-Based Bone Regeneration by Lingling E, Rongjian Lu, Jianwei Sun, Hongbo Li, Wen Xu, Helin Xing, Xing Wang, Tao Cheng, Shuo Zhang, Xiaocao Ma, Rong Zhang, Hongchen Liu

“…In the in vitro three-dimensional culture microenvironment, nHAC/PLA supported hUC-MSCs’ adhesion, proliferation, and differentiation; the microenvironment containing OMD or OMD and rhBMP-7 shortened cell proliferation progression and made osteogenic differentiation progression advance; rhBMP-7 significantly attenuated the inhibiting effect of OMD on hUC-MSCs’ proliferation and significantly enhanced the promoting effect of OMD on gene expression and protein secretion of osteogenic differentiation markers, calcium and phosphorous concentration, and mineralized matrix formation. …”
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Die bemagtiging van die armes by P Verster

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Recent Studies on Nanomaterials as Additives to Lubricants Under Electrified Conditions for Tribology: Review by Khodor Nasser, María J. G. Guimarey, Neuma das Mercês Pereira

“…The tribological performance of nanolubricants in electric drivetrains has gained attention due to the rapid growth of electric vehicles. …”
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Abatacept in the Treatment of Juvenile Dermatomyositis-Associated Calcifications in a 16-Year-Old Girl by Sukesh Sukumaran, Vini Vijayan

“…It is associated with negative impact on the patients’ quality of life due to weakness, functional disability, joint contractures, muscle atrophy, skin ulcers, and secondary infections. Calcinosis can present as superficial nodules or plaques, larger nodular deposits extending into deeper tissue layers, accumulation of calcifications along the fascial planes of muscles or tendons, or an exoskeleton of calcium leading to limitations in mobility and joint contractures. …”
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Rapid Joule-heating synthesis of metal/carbon-based electrocatalysts for efficient carbon dioxide reduction by Weijian Guo, Xueying Cao, Ao Zhou, Wenwen Cai, Jintao Zhang

“…Compared to conventional pyrolysis processes, Joule heating enables rapid heating to elevated temperatures within a short period, effectively preventing the migration and aggregation of metal atoms. Simultaneously, the anchoring effect of defective carbon carriers ensures the uniform distribution of NPs on the carbon supports. …”
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Microstructures and Toughening of TiC-TiB2 Ceramic Composites with Cr-Based Alloy Phase Prepared by Combustion Synthesis in High-Gravity Field by Xuegang Huang, Chun Yin, Zhongmin Zhao, Long Zhang, Junyan Wu

“…The filler phases in ceramic composites are actually Cr-based alloy with a little solidified solution of Ni atoms and Al atoms. The hardness, flexural strength, and fracture toughness of the materials are 18.5 ± 1.5 GPa, 650 ± 35 MPa, and 16.5 ± 1.5 MPa⋅m0.5, respectively. …”
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Modeling factors related to earthquake preparedness: a structural equation modeling approach by Azadeh Fatehpanah, Elham Maraghi, Anthony Coetzer-Liversage, Mahmood Karimy, Amir H. Pakpour, Majed Maripour, Nematollah Jaafarzadeh Haghighi Fard, Marzieh Araban

“…The findings also suggest that disaster education programs should emphasize the importance of attitudes, subjective norms, and perceived behavioral control in promoting disaster preparedness.…”
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A ânsia eterna, a violência, o silenciamento e o grotesco em Os Porcos, de Julia Lopes de Almeida by Iaranda Jurema Ferreira Barbosa

“…O diálogo entre a violência ficcional sofrida pela protagonista do conto e a violência simbólica e empírica vivida pela referida escritora andam ombro a ombro com as inúmeras violações de direitos vivenciadas pelas mulheres até os dias atuais. O referencial teórico compõe-se, principalmente, por Woolf (1928), Telles (1988), Perrot (2005) e Colling (2004). …”
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The potential role of differentially expressed tRNA-derived fragments in high glucose-induced podocytes by Zhenxing Zhang, Yunyang Qiao, Jialing Ji, Chan Huang, Huimin Shi, Weihua Gan, Aiqing Zhang

“…Overexpression of tRF-1:24, one of the most differentially expressed tRFs, attenuated podocyte injury induced by HG. Thus, tRFs might be potential biomarkers for podocyte injury in DKD.…”
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A Modified Dynamic Evolving Neural-Fuzzy Approach to Modeling Customer Satisfaction for Affective Design by C. K. Kwong, K. Y. Fung, Huimin Jiang, K. Y. Chan, Kin Wai Michael Siu

“…A neural-fuzzy network approach has been attempted recently to model customer satisfaction for affective design and it has been proved to be an effective one to deal with the fuzziness and non-linearity of the modeling as well as generate explicit customer satisfaction models. …”
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Ictiosis laminar: presentación de un caso by Rubén Pérez Armas

“…Se orientó un tratamiento integral a la paciente y a la madre, encaminado al consejo genético, manejo sintomático del cuidado de su piel y las interconsultas con las demás especialidades para una atención multidisciplinaria.…”
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Unveiling molecular insights: in silico exploration of TLR4 antagonist for management of dry eye syndrome by Kothandan Sudhakar, Neeru Dugar, Srikanth Jupudi, Ravichandran Ashwin, Kuppusamy Gowthamarajan

“…It is identified by the excessive buildup of reactive oxygen species, leading to substantial corneal epithelial cell demise and ocular surface inflammation attributed to TLR4. In this study, we aimed to identify potential compounds to treat of dry eye syndrome by exploring in silico methods.Methods In this research, molecular docking and dynamics simulation tests were used to examine the effects of selected compounds on TLR4 receptor. …”
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Communicating About Water in the Floridan Aquifer Region: Part 4—The Media’s Role in Water Perceptions by Sadie Hundemer, Shenara Ramadan

“…If ecosystem impacts are not emphasized in the media, they may not be adequately attended to in governance.   …”
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Enhancement of Methane Detection in Tunable Diode Laser Absorption Spectroscopy Using Savitzky–Golay Filtering by Shichao Chen, Xing Tian, Tong Mu, Jun Yuan, Xile Cao, Gang Cheng

“…This improvement demonstrates the effectiveness of the S-G filter in enhancing detection sensitivity, supporting high-precision methane monitoring for atmospheric analysis and various industrial applications.…”
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The impact of Sudan armed conflict and coping strategies on the mental health of the older adult internally displaced persons in Darfur camps by Saif A. Musa, Abdalla A. R. M. Hamid

“…Conclusion The findings of this study suggest that attention should be directed towards fostering positive coping capacity and the provision of psychosocial support services for older adult IDPs in Darfur.…”
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Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients... by Ken Sugimoto, Tomohiro Katsuya, Kei Kamide, Tomomi Fujisawa, Izumi Shimaoka, Mitsuru Ohishi, Ryuichi Morishita, Toshio Ogihara, Hiromi Rakugi

“…We performed a prospective study to examine the genetic effect on the response to a calcium (Ca) channel blocker, azelnidipine and an ACE inhibitor, temocapril treatment in patients with hypertension, as a part of the prior clinical trial, the Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study (ATTEST). Methods and Results. All subjects who gave informed consent for genetic research were divided into two groups: the subjects treated with azelnidipine or temocapril, for 52 weeks. …”
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