Synthesis and Anti-inflammatory Activity of Some Novel 3-(6-Substituted-1, 3-benzothiazole-2-yl)-2-[{(4-substituted phenyl) amino} methyl] quinazolines-4 (3H)-ones by Manish Srivastav, MD. Salahuddin, S. M. Shantakumar

“…A series of novel 3-(6-substituted-1, 3-benzothiazole-2-yl)-2-[{(4-substituted phenyl) amino} methyl] quinazolines-4(3H)-ones were synthesized by treating 2-(chloromethyl)-3-(6-substituted-1, 3-benzothiazole-2-yl) quinazoline-4-(3H)-one (IIa-d) with various substituted amine. …”
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(<i>E</i>)-1-(3-(3-Hydroxy-4-Methoxyphenyl)-1-(3,4,5-Trimethoxyphenyl)allyl)-1<i>H</i>-1,2,4-Triazole and Related Compounds: Their Synthesis and Biological Evaluation as Novel Antimitotic Agents Targeting Breast Cancer by Gloria Ana, Azizah M. Malebari, Sara Noorani, Darren Fayne, Niamh M. O’Boyle, Daniela M. Zisterer, Elisangela Flavia Pimentel, Denise Coutinho Endringer, Mary J. Meegan

“…<b>Background/Objectives:</b> The synthesis of (<i>E</i>)-1-(1,3-diphenylallyl)-1<i>H</i>-1,2,4-triazoles and related compounds as anti-mitotic agents with activity in breast cancer was investigated. …”
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4 3 2 1: A Listening by Priyanka Deshmukh

“…Yet, in all its plainness, Auster’s language is abundantly musical. In his latest novel, 4 3 2 1, by making the reader count down in order to access the first page of the novel, almost like the opening of a piece of music with a 4/4 time signature, Auster calls attention to the sounds his words make, to their music, and to the orality of his prose. …”
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In vitro and in silico insights into antimicrobial and anticancer activities of novel imidazo[2,1-b][1,3,4]thiadiazoles by Deepika Dwarakanath, Yogeesha N. Nayak, Ananda Kulal, Samyak Pandey, K Sreedhara Ranganath Pai, Santosh L. Gaonkar

“…Abstract This study explores the design, synthesis, and evaluation of a novel series of isobenzofuran-based imidazo[2,1-b][1,3,4]thiadiazole derivatives, targeting their antimicrobial and anticancer properties. …”
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Synthesis and Anti-inflammatory Activity of Some Novel 2,4-Diaryl-3,5-bis(arylimino)-1,2,4-thiadiazolidine Derivatives by P. Venkatesh, S. N. Pandeya

“…A series of some novel 2,4-diaryl-3,5-bis(arylimino)-1,2,4-thiadiazolidine derivatives were synthesized and evaluated for anti-inflammatory activity. …”
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Design, Synthesis, Antibacterial and Antifungal Activity of Novel 2-[(E)-2-aryl-1-ethenyl]-3-(2-sulfanyl-1H-benzo[d]imidazole-5-yl)-3,4- dihydro-4-quinolinones by Anisetti Ravinder Nath, Malladi Srinivas Reddy

“…The novel 2-[(E)-2-aryl-1-ethenyl]-3-(2-sulfanyl-1H-benzo[d]imidazole-5-yl)-3,4- dihydro-4-quinolinones (4a-j) analogs were synthesized by Knoevenagel condensation of a solution of 2-methyl-3-(2-sulfanyl-1H-benzo[d]imidazole-5-yl)-3,4-dihydro-4-quinazolinone (3) with aromatic aldehyde in presence of catalytic amount of piperidine. …”
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Biological evaluation of novel 5-((1H-indol-3-yl) methyl)-2-(4-chlorobenzyl)-6-phenyl-imidazo[2,1-b][13,4]thiadiazole derivatives as novel BCL-2 specific inhibitors by Shivangi Sharma, Sadashivamurthy Shamanth, Humaira Siddiqua, Laijau Goyary, Kunigal S. Sagar, Susmita Kumari, Divya Sathees, Gudapureddy Radha, Bibha Choudhary, Sathees C. Raghavan, Kempegowda Mantelingu

“…Previously, we reported a novel BCL2 inhibitor, Disarib, which inhibited BCL2 by predominantly binding to its BH1 domain and exhibited platelet-sparing ability like ABT199, the only FDA-approved BCL2 inhibitor. …”
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Design and In Vitro Biological Evaluation of a Novel Organotin(IV) Complex with 1-(4-Carboxyphenyl)-3-ethyl-3-methylpyrrolidine-2,5-dione by Nebojša Đ. Pantelić, Bojana B. Zmejkovski, Željko Žižak, Nebojša R. Banjac, Bojan Đ. Božić, Tatjana P. Stanojković, Goran N. Kaluđerović

“…A novel triphenyltin(IV) compound with 1-(4-carboxyphenyl)-3-ethyl-3-methylpyrrolidine-2,5-dione was synthesized and characterized by IR, NMR spectroscopy, mass spectrometry, and elemental analysis. …”
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Green ultrasound-assisted three-component click synthesis of novel 1H-1,2,3-triazole carrying benzothiazoles and fluorinated-1,2,4-triazole conjugates and their antimicrobial evaluation by Rezki Nadjet, Aouad Mohamed Reda

“…The present study describes an efficient and ecofriendly, ultrasound, one-pot click cycloaddition approach for the construction of a novel series of 1,4-disubstituted-1,2,3-triazoles tethered with fluorinated 1,2,4-triazole-benzothiazole molecular conjugates. …”
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Synthesis and pharmacological properties of novel guanidine derivatives of quinazoline-2,4(1H,3H)-dione by Alexander A. Ozerov, Daria V. Merezhkina, Natalia A. Gurova, Lyudmila V. Naumenko, Denis A. Babkov, Victor S. Sirotenko, Roman A. Litvinov, Alena S. Taran, Nadezhda V. Stepanova, Umida M. Ibragimova, Alexander A. Spasov, Vadim A. Kosolapov

“…This article presents data on the synthesis and pharmacological activity studies of novel guanidine derivatives of quinazoline-2,4(1H,3H)-dione 6-11 and reference drugs amiloride, rimeporide, zoniporide, dexamethasone, aminoguanidine, and acetylsalicylic acid. …”
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Synthesis and Bioactivity of Some New 3-Alkyl-2,4-diisopropyl-1,2,4,5-tetrahydro-benzo[e][1,3,2]-diazaphosphepine 3-sulfides/selenides by Ch. Mohan, C. Naga Raju, A. Janardhan Rao

“…Preparation of a series of novel seven membered heterocyclic compounds, 3-alkyl-2,4-diisopropyl-1,2,4,5-tetrahydro-benzo[e][1,3,2] diazaphosphepine 3-sulfides / selenides (8a-l) was accomplished in four steps. …”
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Synthesis and characterization of some novel 1,2,4-triazoles, 1,3,4-thiadiazoles and Schiff bases incorporating imidazole moiety as potential antimicrobial agents by Aouad Mohamed Reda, Messali Mouslim, Rezki Nadjet, Ali Adeeb Al-Sheikh, Lesimple Alain

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Synthesis, Antibacterial and Antioxidant Evaluation of Novel 1-(5,7-Dichloro-1,3-benzoxazol-2-yl)-1H-pyrazolo[3,4-b]quinoline Derivatives by N. D. Jayanna, H. M. Vagdevi, J. C. Dharshan, T. R. Prashith Kekuda

“…Some novel 1-(5,7-dichloro-1,3-benzoxazol-2-yl)-1H-pyrazolo[3,4-b]quinoline derivatives 8(a–f) were synthesized by reacting 5,7-dichloro-2-hydrazino-1,3-benzoxazole 4 and substituted-2-chloro-3-quinoline carbaldehydes using p-toluenesulfonic acid (PTSA) as a catalyst for the cyclisation. …”
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4 3 2 1, The Book of Endlessly Forking Paths by Ilana Shiloh

“…4 3 2 1, Paul Auster’s 2017 novel, is a creative exploration of counterfactual thinking – thinking about what might have been. 4 3 2 1 departs from the premise that “the real […] also consist[s] of what could have happened but didn’t”. …”
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Paul Auster’s 4 3 2 1. Past Paradigms by I. B. Siegumfeldt

“…There is something strange about a cast of characters that comes in tetrads centering on duplicate yet different protagonists with identical names, and critics who argue that Auster’s mastodon novel, 4 3 2 1, marks a return to realism fail to take into account the inflated tone of the fabular woven into the texture of the narrative. …”
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Synthesis of 2-(1-Benzofuran-2-yl)-4-(1,3-benzoxazol-2-yl/ 1,3-benzothiazol-2-yl) Quinolines as Blue Green Fluorescent Probes by Yadav D. Bodke, Sheelavanth Shankerrao, Hosanagara N. Harishkumar

“…A series of novel 2-(1-benzofuran-2-yl)-4-(1,3 benzoxazol-2-yl/1,3-benzothiazol-2-yl) quinoline derivatives 4(a–d) were synthesized in one step by the reaction of 2-(1-benzofuran-2-yl) quinoline-4-carboxylic acids 3(a-b) with o-aminophenol and o-amino thiophenol, respectively, using polyphosphoric acid (PPA) as a cyclizing agent. …”
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Design and Theoretical Study of D–A–π–A Organic Sensitizers with [1,2,5]Thiadiazolo[3,4-c]pyridine, [1,2,5]Selenadiazolo[3,4-c]pyridine, and [1,2,5]Oxadiazolo[3,4-c]pyridine π Comp... by O. I. Bolshakov, M. A. Grishina, A. Galushko, V. A. Potemkin, O. A. Rakitin

“…The thienyl bridge in A-block provides a red shift with respect to phenyl bridge for [1,2,5]oxadiazolo[3,4-c]pyridines while the phenyl bridge provides a red shift with respect to thienyl bridge for [1,2,5]selenadiazolo[3,4-c]pyridines. …”
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Novel Syntheses of Some 1, 2, 4-Triazoles as Potent Bacteriocidal Agents by Ram Janam Singh, Dharmendra Kumar Singh

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Novel Catalyst-Free Synthesis of Some 3‑Alkylaminoquinoxaline-2(1H)‑thiones and 3‑Alkyloxyquinoxaline-2(1H)‑thiones in Ethanol by Samir M. El Rayes, Ibrahim A. I. Ali, Walid Fathalla, Mohamed A. Ghanem, Afaf H. El-Sagheer

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Clean Procedure and DFT Study for the Synthesis of 2-Amino-3-ethoxycarbonyl-4-(aryl)-4H-pyrano-[3,2-c]-chromene-5-ones Derivatives: A Novel Class of Potential Antimicrobial and Antioxidant Agents by R. Medyouni, N. Hamdi, R. Ben Said, A. S. Al-Ayed, Fethi Zagrouba

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