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The impact of trauma and how to intervene: a narrative review of psychotraumatology over the past 15 years
Published 2025-12-01Get full text
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11243
Multiomics unravels the complexity of male obesity: a prospective observational study
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11244
A dynamic peripheral immune landscape during human pregnancy
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Angioblast Derived from ES Cells Construct Blood Vessels and Ameliorate Diabetic Polyneuropathy in Mice
Published 2015-01-01Get full text
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Microbial metabolites and immune modulation
Published 2024-12-01“…Propionate, another SCFA, has been linked to the inhibition of histone deacetylases, which are involved in gene regulation, further supporting anti-inflammatory pathways.3,4 These metabolites also modulate macrophage function by promoting a shift toward an anti-inflammatory M2 phenotype, a process essential for resolving inflammation and facilitating tissue repair.5 Additionally, they enhance gut barrier integrity by upregulating proteins involved in epithelial tight junctions, reducing the translocation of harmful microbial components into systemic circulation and thereby mitigating systemic inflammation.6 Secondary bile acids, produced through the microbial biotransformation of primary bile acids synthesized in the liver, exhibit immunomodulatory properties. …”
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Palette-based image recoloring based on moving least squares(基于移动最小二乘的图像重着色)
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11252
Can system dynamics explain long-term hydrological behaviors? The role of endogenous linking structure
Published 2025-01-01Get full text
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11254
Mapping naturally presented T cell antigens in medulloblastoma based on integrative multi-omics
Published 2025-02-01“…Medulloblastoma is shown to be a rich source of tumor-associated antigens, naturally presented on HLA class I and II molecules. Remarkably, most tumor-associated peptides and proteins are subgroup-specific, whereas shared presentation among all subgroups of medulloblastoma (WNT, SHH, Group 3 and Group 4) is rare. …”
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AI-based tumor-infiltrating lymphocyte scoring system for assessing HCC prognosis in patients undergoing liver resection
Published 2025-02-01“…Results: In the discovery cohort, the 5-year overall survival (OS) rates were 34.05% for ATLS-8 low-score and 65.03% for ATLS-8 high-score groups (hazard ratio [HR] 2.40; 95% CI, 1.37–4.19; p = 0.015). These findings were confirmed in validation cohort 1, which had 5-year OS rates of 28.57% and 68.73% (HR 3.38; 95% CI, 1.27–9.02; p = 0.0098), and validation cohort 2, which had 59.26% and 81.48% (HR 2.74; 95% CI, 1.05–7.15; p = 0.031). …”
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smu_1558c-mediated regulation of growth and biofilm formation in Streptococcus mutans
Published 2025-01-01Get full text
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