Efficacy of Manual Hemostasis for Percutaneous Axillary Artery Intra-Aortic Balloon Pump Removal by Rajiv Tayal, Michael DiVita, Christoph W. Sossou, Alexis K. Okoh, Kelly Stelling, James M. McCabe, Amir Kaki, Najam Wasty, David A. Baran

“…They were anticoagulated with weight-based intravenous heparin to maintain an activated partial thromboplastin time (aPTT) of 50–80 seconds. Anticoagulation was discontinued 2 hours prior to the device explantation. …”
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Potentials of Presepsin as a Novel Sepsis Biomarker in Critically Ill Adults: Correlation Analysis with the Current Diagnostic Markers by Mai S. Sater, Nourah Almansour, Zainab Hasan Abdulla Malalla, Salim Fredericks, Muhalab E. Ali, Hayder A. Giha

“…These measures were heart rate (HR), white blood count (WBC), C-reactive protein (CRP), procalcitonin (PCT), lactate plasma concentrations, and measures of hemostasis status (platelets count (PLT), fibrinogen, prothrombin time (PT), activated partial thromboplastin time (APTT), international normalization ratio (INR) and D-dimer). …”
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Penggunaan Play Therapy dalam Mengurangi Rasa Trauma Anak yang Mengalami Kekerasan Seksual by Lia Mita Syahri, Ifdil Ifdil

“…Anak-anak yang mengalami kekerasa seksual mereka akan mengalami rasa takut atau trauma yang amat mendalam baik luka atau trauma yang ditinggalkan melalui fisik atau berupa luka pada bagian tubuh mereka yang menjadi obsek kepuasaan seksual atau trauma (luka) pada bagian psikologis mereka berupa rasa takut dan tidak percaya kepada siapapun atau pun rasa yang mereka sendiri sebagai anak-anak tidak mengerti apa yang telah terjadi pada diri mereka, sehingga kejadian yang mereka alami yaitu kekerasan seksual yang mereka dapatkan akan menganggu fikiran mereka, anak-anak akan rentan lebih lama mengingat kejadian tersebut, sehingga dalam hal ini teknik play therapy (Terapi bermain) dalam play therapy kegiatan utama yang dilakukan adalah bermain, maka dari itu diharapkan dalam penggunaan play therapy anak-anak yang mengalami kejadian kekerasan seksual dapat kembali ke dunianya yaitu bermain dan dapat melupakan kejadian kekerasan seksual yang mereka rasakan, anak-anak kembali dalam kegiatannya bermain dan kembali lagi percaya kepada lingkungan mereka yang dapat menjaga mereka dari kejadian yang menyakitkan.…”
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Subchronic Toxicity Study of Alternanthera philoxeroides in Swiss Albino Mice Having Antioxidant and Anticoagulant Activities by Shahad Saif Khandker, Morshed Alam, Forhad Uddin, Ummay Mahfuza Shapla, Nafisa Lubna, Tanusree Amy Mazumder, Mahfuza Marzan, Milon Mondal, Md Ibrahim Khalil, Nurul Karim, Md Salman Shakil, Md Sakib Hossen

“…We estimated phytochemicals content as well as antioxidant activity through DPPH, NO, CUPRAC, and reducing power assays, followed by the anticoagulant activities of PT  and aPTT  and bioactive compounds using HPLC. To confirm the biocompatibility of A. philoxeroides extracts, histopathological and hematological parameters were examined in a mice model. …”
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The Affirmative Action and Household Income Status of the Batwa Community Evicted From Bwindi Impenetrable Forest National Park, Kanungu District, Uganda by Saulo, Katariko

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Gut microbiota derived DCA enhances FOLFOX efficacy via Ugt1a6b mediated enterohepatic circulation in colon cancer by Qian Fang, Xiaoying Hou, Limei Fan, Yufei Deng, Xiaoxuan Li, Hongyun Zhang, Haiping Wang, Zhengqi Fu, Binlian Sun, Xiji Shu, Hongzhi Du, Yuchen Liu

“…Further, based on the system screen of 15 bile acids on FOLFOX efficacy via MTT, colony formation and flow cytometry assay, Deoxycholic Acid (DCA) and Glycodeoxycholic Acid (GDCA) were annotated as potential modulators of FOLFOX efficacy. …”
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Combining Innovative Bioink and Low Cell Density for the Production of 3D-Bioprinted Cartilage Substitutes: A Pilot Study by Christel Henrionnet, Léa Pourchet, Paul Neybecker, Océane Messaoudi, Pierre Gillet, Damien Loeuille, Didier Mainard, Christophe Marquette, Astrid Pinzano

“…The influence of the bioprinting process and chondrogenic differentiation on MSC metabolism, gene profiles, and extracellular matrix (ECM) production at two different MSC concentrations (1 million or 2 million cells/mL) was assessed on day 28 (D28) by using MTT tests, real-time RT-PCR, and histology and immunohistochemistry, respectively. …”
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Exploring the risk factors of blood transfusion in patients with isolated traumatic brain injury based on machine learning prediction models by LIU Wei, XIONG Ziqing, WU Chenggao, LE Aiping

“…There were significant differences (P<0.05) in gender, age, HR, clinical diagnosis, skull fracture, treatment methods, hemorrhagic shock, GCS, K, Ca, PT, APTT, INR, RBC, Hct, Hb and Plt between transfusion and non transfusion patients; Moreover, the LOS, incidence of complications, mechanical ventilation rate, ICU admission rate, readmission rate within 90 days and in-hospital mortality rate of transfusion patients were all higher than those of the non transfusion group (P<0.05). …”
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Differences of simulated ankle dorsiflexion limitation on lower extremity biomechanics during long jump takeoff by Zanni Zhang, Datao Xu, Xiangli Gao, Huiyu Zhou, Julien S. Baker, Zsolt Radak, Yaodong Gu

“…A Vicon motion capture system with eight cameras and an AMTI force platform were used to collect biomechanical data simultaneously during the long jump. …”
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Efficacy of Group O Washed Red Blood Cell Transfusion on Vital Signs and Hematologic Stability in Trauma Patients With Different Blood Types by Gou XJ, Li LF, He XL, Chen X, Yu AY, Tian WY

“…Significant changes were noted in platelet count (PLT), activated partial thromboplastin time (APTT), and C-reactive protein (CRP) following transfusion (P < 0.05). …”
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Analysis of Risk Factors for Hemorrhagic Transformation of Cerebral Infarction and Recurrence of Cerebral Infarction: A Retrospective Study on Cerebral Infarction Patients with or... by Bao P, Ling L, Xiang L, Liu X, Zhang J, Yue W

“…ROC analysis was utilized, and AUCs were showed the diagnostic values of the risk factors.Results: Compared to the patients with non-hemorrhage cerebral infarction, the patients with hemorrhage cerebral infarction were older and had higher Neutrophil infiltration, AST expression, globulin and BUN, while had lower ALT expression, triglyceride, PT, APTT, homocysteine, d-dimer, CRP and glycosylated hemoglobin. …”
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Synchrotron X-ray imaging study on the mechanism of solids transfer to bitumen froth during oil sands flotation 1: True flotation by Hanyu Zhang, Liuyin Xia, Ning Zhu, Sergey Gasilov, Iris He, Xiaofan Ding

“…The collected bitumen froth was immediately characterized using synchrotron-based X-ray imaging by a monochromatic X-ray with photon energy of 60 keV provided by 05ID-2 beamline of the BioMedical Imaging and Therapy (BMIT) facility at the Canadian Light Source (CLS). …”
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Determinants of mortality and prolonged hospital stay among dengue patients attending tertiary care hospital: a cross-sectional retrospective analysis by Yusra Habib Khan, Tauqeer Hussain Mallhi, Amer Hayat Khan, Azmi Sarriff, Azreen Syazril Adnan

“…Multivariate analysis showed that dengue haemorrhagic fever (OR 2.3), elevated alkaline phosphatase (ALP) (OR 2.3), prolonged prothrombin time (PT) (OR 1.7), activated partial thromboplastin time (aPTT) (OR 1.9) and multiple-organ dysfunctions (OR 2.1) were independently associated with prolonged hospitalisation. …”
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Body Mass Index and 1-Year Unplanned Readmission in Chinese Patients with Acute Myocardial Infarction: A Retrospective Cohort Study by Dandan Sun, Qingyun Zhang, Wei Li, Haichen Wang

“…Covariates involved in this study included age, gender, TC, triglyceride, HDL-C, LDL-C, PT, APTT, INR, creatinine, HGB, LVEF, discharge medication, marital status, educational level, COPD, diabetes mellitus, heart failure, history of ischemic stroke, history of hemorrhagic stroke, arrhythmia, and hypertension. …”
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A new score for predicting intracranial hemorrhage in patients using anticoagulant drugs by Fuxin Ma, Zhiwei Zeng, Jiana Chen, Chengfu Guan, Wenlin Xu, Chunhua Wang, Jinhua Zhang

“…Multifactorial analysis showed that male, leukoaraiosis, high risk of falls, APTT ≥ 45.4 s, and FIB ≥ 4.2 g/L were independent risk factors for cerebral hemorrhage, and β-blockers were protective factors. …”
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Predictive Laboratory Markers for Gastrointestinal Complications in Children with Henoch-Sch&ouml;nlein Purpura by Guo Q, Xia S, Ding Y, Liu F

“…Detailed demographic and laboratory data, including WBC count, lymphocyte count, neutrophil count, platelet count, hemoglobin, NLR, PLR, MPV, MPR, C-reactive protein, ESR, albumin, BUN, creatinine, sodium, potassium, calcium, IgA, PT, aPTT, and INR, were collected. GIS complications was classified based on clinical symptoms and diagnostic findings. …”
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Development and validation of a nomogram to predict survival in septic patients with heart failure in the intensive care unit by Tong Tong, Yikun Guo, Qingqing Wang, Xiaoning Sun, Ziyi Sun, Yuhan Yang, Xiaoxiao Zhang, Kuiwu Yao

“…A nomogram model was developed to predict short-term survival probabilities, using 13 variables: age, pneumonia, endotracheal intubation, mechanical ventilation, potassium (K), anion gap (AG), lactate (Lac), activated partial thromboplastin time (APTT), white blood cell count (WBC), red cell distribution width (RDW), hemoglobin-to-red cell distribution width ratio (HRR), Sequential Organ Failure Assessment (SOFA) score, and Charlson Comorbidity Index (CCI). …”
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凝血相关指标在关节假体周围感染中的诊断价值 by 吴小宇, 叶勇裕, 潘柏祺, 胡玄韬, 郑霖力, 陈蔚深, 张紫机, 盛璞义

“…结果本研究纳入的指标包括血浆纤维蛋白原（FBG），凝血酶原时间（PT），凝血酶时间（TT），活化部分凝血活酶时间（APTT），血小板（PLT），平均血小板体积（MPV），血小板分布宽度（PDW），血小板比容（PCT），PLT/MPV，PLT/PDW和PLT/PCT。…”
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Preclinical pharmaco-toxicological screening of biomimetic melanin-like nanoparticles as a potential therapeutic strategy for cutaneous melanoma by Iasmina Marcovici, Iasmina Marcovici, Raul Chioibas, Raul Chioibas, Istvan Zupko, Iulia Pinzaru, Iulia Pinzaru, Alina Moaca, Alina Moaca, Adriana Ledeti, Adriana Ledeti, Lucian Barbu-Tudoran, Lucian Barbu-Tudoran, Andreea Geamantan, Andreea Geamantan, Iasmina Predescu, Iasmina Predescu, Cristina Adriana Dehelean, Cristina Adriana Dehelean

“…The cytotoxic, anti-migratory, anti-clonogenic, pro-oxidant and pro-apoptotic properties of MEL-NPs were investigated in vitro by applying the MTT viability test, bright-field and immunofluorescence microscopy, DCFDA/H2DCFDA test, scratch assay, colony formation assay, and RT-qPCR. …”
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Anti-Inflammatory Potential and Synergic Activities of <i>Eclipta prostrata</i> (L.) L. Leaf-Derived Ointment Formulation in Combination with the Non-Steroidal Anti-Inflammatory Dr... by Muhammad M. Poyil, Mohammed H. Karrar Alsharif, Mahmoud H. El-Bidawy, Salman Bin Dayel, Mohammed Sarosh Khan, Zainab Mohammed M. Omar, Alaaeldin Ahmed Mohamed, Reda M. Fayyad, Tarig Gasim Mohamed Alarabi, Hesham A. Khairy, Nasraddin Othman Bahakim, Mohamed A. Samhan, Abd El-Lateef Saeed Abd El-Lateef

“…Heat-induced haemolysis showed 2.5% and 2.4% of haemolysis at 5 mg of <i>E. prostrata</i> alone and in combination with diclofenac, respectively. An MTT assay performed using L₉₂₉ cells proved that the extract has no cytotoxic effect. …”
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