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Efficacy of caerulomycin A in modulating macrophage polarization and cytokine response in a murine model of lipopolysaccharide-induced sepsis
Published 2025-01-01“…For in-vitro assays using the RAW264.7 macrophage cell line, the concentration of caeA that was non-toxic to cell survival was screened using the MTT assay, followed by the analyses by qRT-PCR, ELISA, Western blot and flow cytometry for M1/M2 type macrophage markers (CD86, NOS2, CD206, ARG1) and inflammatory factors (IL-1β, IL-6, TNF-α, IL-4, and IL-10) expression. …”
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3643
IGF2BP2 Regulates the Progression of Alzheimer's Disease Through m6A‐Mediated NLRP3 Inflammasome
Published 2025-01-01“…Materials & Methods The mRNA and protein expression level were determined using RT‐qPCR and western blot, respectively. MTT assay was carried out to evaluate cell viability. …”
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3644
Circ-ADAM9 Promotes High Glucose-Induced Retinal Pigment Epithelial Cell Injury in DR via Regulating miR-338-3p/CARM1 Axis
Published 2022-01-01“…Cell proliferation and apoptosis were determined using MTT assay, EdU assay, and flow cytometry. The protein expression of apoptosis markers and CARM1 was examined by the western blot analysis. …”
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3645
An in-vivo herb-drug interaction study of IME-9 and glimepiride in nicotinamide-STZ-induced diabetic rats
Published 2025-05-01“…Toxicity assessments were carried out utilizing the MTT assay. Results: Concurrent administration of GP and IME-9 in diabetic rats resulted in elevated Cmax and AUC0-48hrs of GP, while no alteration in Tmax was noticed. …”
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3646
Socialinio darbuotojo konfliktų su klientais valdymo patirtys
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3647
Human endometrial stem cell-derived small extracellular vesicles enhance neurite outgrowth and peripheral nerve regeneration through activating the PI3K/AKT signaling pathway
Published 2025-01-01“…Also, dil-staining of hEnSC-derived small EVs was done to determine the penetration of hEnSC-derived small EVs into PC12 cells. The MTT assay, scratch assay, and western blot assay were applied to PC12 cells that were exposed to different concentrations of small EVs (0, 50, 100, and 150 µg/ml). …”
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3648
PASYVIOSIOS MAGISTRALĖS PANAUDOJIMAS OPTINĖS PRIEIGOS TINKLUOSE
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Two previously undescribed triterpenoid saponins from the roots and rhizomes of Caulophyllum robustum Maxim
Published 2025-01-01“…The cytotoxicity of these compounds on human cancer cell lines was analyzed using MTT method. Compounds 6 and 9 exhibit cytotoxicity towards these three types of human cancer cells (<10 μM). …”
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3652
Biological activity research of male papaya flowers Carica papaya L. on some common cancer cell lines
Published 2024-09-01“…The highest polyphenol content in the water fraction extract is 88.15 ± 1.37 µg GAE/mg extract, corresponding to the best antioxidant activity with an EC50 of 431.10 µg/mL measured by the DPPH method. Using the MTT method, the extract fractions also exhibited cytotoxic activity against HepG2 liver cancer cells, K562 leukemia cells, and B16F10 skin cancer cells. …”
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3653
Effects of Ginsenoside Biopolymer Nanoparticles on the Malignant Behavior of Non-Small-Cell Lung Cancer
Published 2020-01-01“…The proliferation of H125 cells was measured using MTT assay, and the Transwell assay was used to detect the invasiveness of H125 cells. …”
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3654
Identification of a Novel Anticancer Oligopeptide from Perilla frutescens (L.) Britt. and Its Enhanced Anticancer Effect by Targeted Nanoparticles In Vitro
Published 2018-01-01“…The structure of the oligopeptide was determined using a peptide sequencer, and its anticancer effect was examined by the MTT assay. PSO (Perilla seed oligopeptide), the most potent anticancer oligopeptide, was loaded by chitosan nanoparticles (NPs) modified by hyaluronic acid (HA). …”
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Vilniaus kolegijos psichosocialinės aplinkos vertinimas studentų požiūriu
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3656
An indole alkaloid from a tribal folklore inhibits immediate early event in HSV-2 infected cells with therapeutic efficacy in vaginally infected mice.
Published 2013-01-01“…The cytotoxicity (CC50), effective concentrations (EC50) and the mode of action of HM was determined by MTT, plaque reduction, time-of-addition, immunofluorescence (IFA), Western blot, qRT-PCR, EMSA, supershift and co-immunoprecipitation assays; while the in vivo toxicity and efficacy was evaluated in BALB/c mice. …”
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Screening Southeast Asian medicinal plants: Clausena lansium, Leea indica, Strobilanthes crispa, Vitex trifolia for anti-platelet aggregation and blood coagulation effects
Published 2025-02-01“…All extracts prolonged PT and aPTT, with Leea indica and Strobilanthes crispa being most potent. …”
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3658
Integrating biomarkers for hemostatic disorders into computational models of blood clot formation: A systematic review
Published 2024-12-01“…Results indicate that commonly used biomarkers such as D-dimer, PT, and APTT are rarely and superficially integrated into computational blood coagulation models. …”
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3659
Efektivitas E-booklet Tentang ASI Eksklusif dalam Peningkatan Pengetahuan dan Sikap Ibu Hamil Trimester III
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3660
Hubungan Hiperglikemia dengan Prothrombin Time pada Mencit (Mus musculus) yang Diinduksi Aloksan
Published 2015-01-01“…The subject were white mice (Mus musculus) who have met the inclusion and exclusion criteria. The subject were divided as hyperglycemia group (induced with aloxan) and control group. …”
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