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Cellular Cholesterol Loss Impairs Synaptic Vesicle Mobility via the CAMK2/Synapsin-1 Signaling Pathway
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6583
Do serial troponins predict the need for cardiac evaluation in trauma patients after ground-level fall?
Published 2024-10-01“…Analysis was done with cut-off values of 30 ng/L, 50 ng/L, 70 ng/L, and 90 ng/L; a troponin T threshold of 19 ng/L was significant for cardiology consult (p=0.01) and cardiology follow-up (p=0.04). …”
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6585
Ursodeoxycholic acid protects against sepsis-induced acute kidney injury by activating Nrf2/HO-1 and inhibiting NF-κB pathway
Published 2025-01-01“…UDCA (15, 30, and 60 mg/kg) was administered intraperitoneally once daily for 7 days before LPS injection. …”
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6586
Geographical Differences in the Safety and Efficacy of Tofacitinib Versus TNFi: A Post Hoc Analysis of ORAL Surveillance
Published 2024-07-01“…Abstract Introduction In ORAL Surveillance, incidence rates (IRs) of major adverse cardiovascular events (MACE) and malignancies (excluding non-melanoma skin cancer [NMSC]) in cardiovascular (CV)-risk-enriched patients with rheumatoid arthritis (RA) were numerically greater with tofacitinib in North America versus the rest of the world, due to underlying risk factors. Here, we evaluated the safety and efficacy of tofacitinib versus tumor necrosis factor inhibitors (TNFi) among patients with RA across geographical regions. …”
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6587
Anxiety and burnout in infectious disease nurses: the role of perceived stress and resilience
Published 2025-01-01“…However, prior to this study, no research had delved into the underlying mechanism linking anxiety to burnout symptoms among infectious disease nurses. …”
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6589
The Role of Autophagy in Copper-Induced Apoptosis and Developmental Neurotoxicity in SH-SY5Y Cells
Published 2025-01-01“…In this study, we established an in vitro model of Cu<sup>2+</sup>-exposed (0, 15, 30, 60 and 120 μM) SH-SY5Y cells to explore the role of autophagy in copper-induced developmental neurotoxicity. …”
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6590
Altered brain functional network connectivity and topology in type 2 diabetes mellitus
Published 2025-01-01“…These findings suggest that brain functional network connectivity and topology could serve as imaging biomarkers, providing insights into the underlying neuropathological processes associated with T2DM-related cognitive impairment.…”
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Acute Concurrent Exercise Improves Inhibitory Control Without Mediating the Role of Lactate: An Event-Related Potential Study
Published 2025-01-01“…Moreover, exploring the mechanisms underlying the effects of acute exercise on EFs contributes to scientific comprehension, with lactate recognized as a crucial candidate positively correlated with EFs. …”
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6594
Plasmodium falciparum genetic diversity and multiplicity of infection based on msp‑1, msp‑2, glurp and microsatellite genetic markers in sub-Saharan Africa: a systematic review and...
Published 2024“…The overall pooled mean MOI was 2.09 (95% CI: 1.88–2.30), with regional variations: East (2.05), Central (2.37), Southern (2.16), and West Africa (1.96). …”
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6595
Rhoifolin Suppresses Cell Proliferation and Induces Apoptosis in Hepatocellular Carcinoma Cells In Vitro and In Vivo
Published 2025-01-01“…<b>Objectives:</b> Exploring the potent inhibitory activities and underlying mechanisms of ROF on HCC cells. <b>Methods:</b> The suppressive effect of ROF on HCC cells were assessed via CCK8 assay, apoptosis assay, cell cycle analysis and xenograft tumor mouse model. …”
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6596
Impact of cascade reservoir on the sources of organic matter in sediments of Lancang river
Published 2025-01-01“…Summary: The construction of dams to intercept natural rivers constitutes the most severe human activity influencing the underlying surface. This study focuses on four cascade reservoirs of the Lancang River and explores their impact on the migration of organic matter in sediments. …”
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6598
Effects of pesticide dichlorvos on liver injury in rats and related toxicity mechanisms
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6599
A feedback loop between Paxillin and Yorkie sustains Drosophila intestinal homeostasis and regeneration
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6600
Clinical manifestations of COVID-19 infection and its impact on the outcome in children and adolescents with benign and malignant hematological disease in Egypt: a single-center ex...
Published 2025-01-01“…Mortality was associated with abnormal neurological examination in COVID-19-positive patients with underlying hematological disease.…”
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