The Protective Effect of Mangiferin on Formaldehyde-Induced HT22 Cell Damage and Cognitive Impairment by Fan Chen, Na Wang, Xinyan Tian, Juan Su, Yan Qin, Rongqiao He, Xiaping He

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Astrocyte-Derived Interleukin 11 Modulates Astrocyte–Microglia Crosstalk via Nuclear Factor-κB Signaling Pathway in Sepsis-Associated Encephalopathy by Dandan Zhu, Peng Wang, Xiyue Chen, Kaituo Wang, Yunsong Wu, Min Zhang, Jianhua Qin

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Local electrical stimulation: introduction to the problem by Lev G. Agasarov, Maxim Yu. Yakovlev, Tatyana V. Konchugova, Larisa A. Marchenkova, Victor A. Drobyshev, Tatyana V. Apkhanova, Tatyana E. Belousova, Tatyana V. Marfina, Nadezhda V. Gushchina, Valeria A. Vasileva, Anastasia A. Mukhina, Irina A. Grishechkina, Tatyana K. Chernyavskaya, Elena P. Ivanova

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Potential prebiotic effects of nonabsorptive components of Keemun and Dianhong black tea: an in vitro study by Wenjing Liao, Wenjiao Li, Suyu Liu, Dong Tang, Yunxi Chen, Yijun Wang, Zhongwen Xie, Jinbao Huang

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Protocols for the application of human embryonic stem cell-derived neurons for aging modeling and gene manipulation by Hui Zhang, Shuhui Sun, Juan Carlos Izpisua Belmonte, Guang-Hui Liu, Si Wang, Weiqi Zhang, Jing Qu

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Histone demethylases in autophagy and inflammation by Yaoyao Ma, Wenting Lv, Yi Guo, Tong Yin, Yujie Bai, Ziqi Liu, Chao Chen, WenjuanYang, Jiayi Feng, Wenbin Qian, Ruiling Tang, Yanting Su, Shigang Shan, Huifen Dong, Yongfen Bao, Lihua Qu

“…Specifically, It focused on the specific regulatory mechanisms underlying the activation or inhibition of autophagy, as well as their abnormal expression in inflammatory responses. …”
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Beyond Hormone Receptors: liquid biopsy tools to unveil new clinical meanings and empower therapeutic decision-making in Luminal-like metastatic breast cancer by Brenno Pastò, Riccardo Vida, Arianna Dri, Lorenzo Foffano, Serena Della Rossa, Lorenzo Gerratana, Fabio Puglisi

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Small molecule APOL1 inhibitors as a precision medicine approach for APOL1-mediated kidney disease by Brandon Zimmerman, Leslie A. Dakin, Anne Fortier, Evanthia Nanou, Angelo Blasio, James Mann, Howard Miller, Marissa Fletcher, Tiansheng Wang, Suganthini Nanthakumar, Gizelle McCarthy, Caline Matar, Prachi Matsye, Guanyu Wang, Phillip Snyder, Kevin Daniel, Harsha Swamy, Kelly Sullivan, Franklin Bright, Audrey Powers, Kevin J. Gagnon, Fan Lu, Steven Paula, Suvarna Khare-Pandit, Larry Henry, Martine Hamel, Francois Denis, Olivier Nicolas, Niresh Hariparsad, Shyamesh Kumar, Jennifer Proctor, Timothy Senter, Brinley Furey, Mark E. Bunnage

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Chemical characterization of Siraitia grosvenorii granules and their efficacy and mechanism of action on PM2.5-induced acute lung injury by Qi Shao, Yan Zhao, YuYu Shi, Fafeng Cheng, ZeHan Zhang, Ying Liu, ChangXiang Li, ZiLin Ren, Hua Bai, Haojie Cheng, Rolando Maddela, Junqiang Tian, Xueqian Wang

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Predicting the tumor microenvironment composition and immunotherapy response in non-small cell lung cancer from digital histopathology images by Sushant Patkar, Alex Chen, Alina Basnet, Amber Bixby, Rahul Rajendran, Rachel Chernet, Susan Faso, Prashanth Ashok Kumar, Devashish Desai, Ola El-Zammar, Christopher Curtiss, Saverio J. Carello, Michel R. Nasr, Peter Choyke, Stephanie Harmon, Baris Turkbey, Tamara Jamaspishvili

“…We show that HistoTME accurately predicts the expression of 30 distinct cell type-specific molecular signatures directly from whole slide images, achieving an average Pearson correlation of 0.5 with the ground truth on independent tumor cohorts. …”
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Medical Assistance in Dying for Persons Suffering Solely from Mental Illness in Canada by Chloe Eunice Panganiban, Srushhti Trivedi

“…Research provides evidence that MAiD improves autonomy: A study among psychiatric patients found that 8 of 48 psychiatric patients said the mere option of accessing MAiD was enough to assess their future options for living wholly.[8] These findings complement a study entailing interviews with 30 adults who have mental illness, which emphasized that the ability to access MAiD allows individuals to analyze their quality of life, envision their desired future, and make decisions accordingly.[9] Although not all participants agreed that mental illness as the only underlying medical condition was appropriate for MAiD eligibility, many participants agreed that patient autonomy in decision-making was paramount and should be respected. …”
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A Tensioned Human Skin Explant Model Used for Preliminary Assessment of Chemexfoliant-Stimulated Bioeffects by Michael J. Conneely, Jin Namkoong, Francis Allison, S. Kyoko Hirata Tsutsumi, Dominic Grussu, Ryan Willis, Kyle Henderson, Paul A. Campbell, Melissa Moy, Ewelina Lesniak, Joanna Wu, Robyn P. Hickerson

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Endocrinopathies after Allogeneic and Autologous Transplantation of Hematopoietic Stem Cells by Francesco Orio, Giovanna Muscogiuri, Stefano Palomba, Bianca Serio, Mariarosaria Sessa, Valentina Giudice, Idalucia Ferrara, Libuse Tauchmanovà, Annamaria Colao, Carmine Selleri

“…Dysfunctions of the hypothalamus-pituitary-growth hormone/insulin growth factor-I axis, hypothalamus-pituitary-thyroid axis, and hypothalamus-pituitary-adrenal axis were documented as later complicances, occurring in about 10, 30, and 40–50% of transplanted patients, respectively. …”
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Lung Matrix Metalloproteinase Activation following Partial Hepatic Ischemia/Reperfusion Injury in Rats by Giuseppina Palladini, Andrea Ferrigno, Vittoria Rizzo, Eleonora Tarantola, Vittorio Bertone, Isabel Freitas, Stefano Perlini, Plinio Richelmi, Mariapia Vairetti

“…Male Sprague-Dawley rats were subjected to 30 min partial hepatic ischemia by clamping the hepatic artery and the portal vein. …”
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Electroacupuncture Treatment Alleviates Central Poststroke Pain by Inhibiting Brain Neuronal Apoptosis and Aberrant Astrocyte Activation by Gui-Hua Tian, Shan-Shan Tao, Man-Tang Chen, Yu-Sang Li, You-Ping Li, Hong-Cai Shang, Xiao-Yi Tang, Jian-Xin Chen, He-Bin Tang

“…Electroacupuncture (EA) is reported to effectively relieve the central poststroke pain (CPSP). However, the underlying mechanism remains unclear. The present study investigated the detailed mechanisms of action of EA treatment at different frequencies for CPSP. …”
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Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Ol... by Francis M. Finucane, Stephen J. Sharp, Mensud Hatunic, Alison Sleigh, Ema De Lucia Rolfe, Avan Aihie Sayer, Cyrus Cooper, Simon J. Griffin, David B. Savage, Nicholas J. Wareham

“…Introduction. The mechanisms underlying the association between insulin resistance and intrahepatic lipid (IHL) accumulation are not completely understood. …”
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Mouse Umbilical Cord Mesenchymal Stem Cell Paracrine Alleviates Renal Fibrosis in Diabetic Nephropathy by Reducing Myofibroblast Transdifferentiation and Cell Proliferation and Upr... by Hongde Li, Pengfei Rong, Xiaoqian Ma, Wei Nie, Yan Chen, Juan Zhang, Qiong Dong, Min Yang, Wei Wang

“…Together, these findings reveal the mechanisms underlying the therapeutic effects of UC-MSCs on renal fibrosis in DN and provide the evidence for DN cell-free therapy based on UC-MSCs in the future.…”
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Cementum attachment protein‐derived peptide induces cementum formation by Lía Hoz Rodríguez, Maricela Santana Vázquez, Luis Fernando Ramírez González, Gonzalo Montoya Ayala, Sonia López Letayf, A. Sampath Narayanan, Higinio Arzate

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Association of socio-demographic characteristics, comorbidities, lifestyle habits, and saliva parameters with dental caries in adults with obesity by Virginie Chuy, Marie Mayoute, Maud Monsaingeon-Henry, Blandine Gatta-Cherifi, Élise Arrivé

“…Acting on salivary composition may also be of interest, and further studies are required to explore the underlying mechanisms. …”
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Altered resting-state cerebral blood flow and its relationship with molecular architecture in tremor dominant Parkinson’s disease by Shangpei Wang, Yajie Cai, Yibin Zhao, Yongqiang Yu, Xianwen Chen, Longsheng Wang

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