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  1. 6341

    New drugs for acute kidney injury by Geoffroy Hariri, Matthieu Legrand

    Published 2025-01-01
    “…These advancements highlight the intricate and multifaceted nature of the mechanisms underlying AKI, which could explain the challenge of identifying an effective treatment. …”
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  3. 6343

    Gastrointestinal Parasites With Their Risk Factors in Tharu Indigenous People in Southern Nepal: A Cross‐Sectional Study by Pinki Kumari Chaudhary, Tirth Raj Ghimire

    Published 2025-01-01
    “…These risk factors are the underlying cause of GI parasitic infections in many developing nations, including Nepal. …”
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  4. 6344

    PALLIATIVE PANCREATODUODENAL RESECTION IN PANCREATIC HEAD CANCER by T. G. Gevorkyan, I. A. Faynshteyn

    Published 2018-03-01
    “…Palliative pancreatoduodenal resection with a common pancreatic cancer in some cases can be an operation of choice that effectively eliminates the underlying pathological process and its complications in the form of mechanical jaundice, duodenal obstruction and pain syndrome and significantly improve the quality of life of patients.…”
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    Beyond image: evaluating the perceived effectiveness of workplace mental health programs in the insurance sector by Isabel Barbosa, Elizabeth Real de Oliveira

    Published 2025-01-01
    “…Methods A qualitative study used 30 semi-structured interviews with individuals from large insurance companies in Portugal. …”
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  9. 6349

    Nitrous oxide exerts rewarding effect via regulating D1 receptor and BDNF pathway in ventral tegmental area-nucleus accumbens dopamine circuit by Wen-Qi Li, Sheng-Nan Liu, Si-Chang Yang, Xiang Lin, Zhang-Jin Zhang

    Published 2025-01-01
    “…This study aimed to examine its rewarding effect and the underlying mechanisms. The exposure of mice to a subanesthetic concentration (20%) of N2O for 30 min for 4 consecutive days paired with N2O in the morning and paired with the air in the afternoon produced apparent rewarding behavior in the conditioned place preference (CPP) paradigm. …”
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  10. 6350

    A Comparative Study between outcome of 25% glucose in glycerin and submucosal human placental extract injection in the management of Primary Atrophic Rhinitis by Amlan Debbarma, Bidhan Das, Santanu Saha

    Published 2025-02-01
    “…Progressive atrophy of nasal mucosa and underlying turbinates, formation of scanty viscid secretion and crusts causing foul odor are the cardinal features of this disease. …”
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  12. 6352

    Identifying mechanisms that shape the food environment in long-term healthcare facilities in the Netherlands: a participatory system dynamics approach by Joline J. Wierda, S. Coosje Dijkstra, Tamika M. Wopereis, Sanne K. Djojosoeparto, Maartje P. Poelman

    Published 2025-01-01
    “…Conclusions This study gained a comprehensive, collectively acknowledged understanding of the system dynamics underlying the food environment in Dutch long-term healthcare institutions. …”
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  13. 6353

    La gestion de l’eau à Bibracte (Saône-et-Loire), avant et après la Conquête romaine by Laetitia Borau

    Published 2020-12-01
    “…It covered a surface of 30 m2. Dated to the beginning of the 1st c. BC, it was also built of stone (quadrangular and irregular-shaped blocks) and waterproofed with clay (the bottom and the foundation trench). …”
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    Developing a translational research framework for MDD: combining biomolecular mechanisms with a spiraling risk factor model by Max van Baalen, Lars van der Velden, Toon van der Gronde, Toon van der Gronde, Toine Pieters

    Published 2025-01-01
    “…ObjectiveThe global incidence and burden of Major Depressive Disorder (MDD) are increasing annually, with current antidepressant treatments proving ineffective for 30-40% of patients. Biomolecular mechanisms within the microbiota-gut-brain axis (MGBA) may significantly contribute to MDD, potentially paving the way for novel treatment approaches. …”
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    Multi-omics analyses identify gut microbiota-fecal metabolites-brain-cognition pathways in the Alzheimer’s disease continuum by Han Zhao, Xia Zhou, Yu Song, Wenming Zhao, Zhongwu Sun, Jiajia Zhu, Yongqiang Yu

    Published 2025-02-01
    “…Abstract Background Gut microbiota dysbiosis is linked to Alzheimer’s disease (AD), but our understanding of the molecular and neuropathological bases underlying such association remains fragmentary. Methods Using 16S rDNA amplicon sequencing, untargeted metabolomics, and multi-modal magnetic resonance imaging, we examined group differences in gut microbiome, fecal metabolome, neuroimaging measures, and cognitive variables across 30 patients with AD, 75 individuals with mild cognitive impairment (MCI), and 61 healthy controls (HC). …”
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  20. 6360

    Efficacy and compatibility mechanism of bear bile powder in Shexiang Tongxin dropping pills for acute myocardial infarction treatment by Yu Luo, Fangmin Zhang, Lidan Zhu, Jianfeng Ye, Hong-ye Pan, Xiaoyan Lu, Xiaohui Fan

    Published 2025-01-01
    “…Additionally, the combination treatment induced a 62.34% gene reversion rate compared with 55.56% for BBP and 30.20% for CF treatment alone. Modulation of endothelin 1 and growth factor receptor-bound protein 2 was identified as a key synergistic mechanism underlying the anti-AMI effects of BBP in STDP. …”
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