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New drugs for acute kidney injury
Published 2025-01-01“…These advancements highlight the intricate and multifaceted nature of the mechanisms underlying AKI, which could explain the challenge of identifying an effective treatment. …”
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6342
Understanding City-Wide Ride-Sourcing Travel Flow: A Geographically Weighted Regression Approach
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6343
Gastrointestinal Parasites With Their Risk Factors in Tharu Indigenous People in Southern Nepal: A Cross‐Sectional Study
Published 2025-01-01“…These risk factors are the underlying cause of GI parasitic infections in many developing nations, including Nepal. …”
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6344
PALLIATIVE PANCREATODUODENAL RESECTION IN PANCREATIC HEAD CANCER
Published 2018-03-01“…Palliative pancreatoduodenal resection with a common pancreatic cancer in some cases can be an operation of choice that effectively eliminates the underlying pathological process and its complications in the form of mechanical jaundice, duodenal obstruction and pain syndrome and significantly improve the quality of life of patients.…”
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6345
High Expression of UPK3A Promotes the Progression of Gastric Cancer Cells by Inactivating p53 Pathway
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6346
Multiomics Integrated Analysis Identifies SLC24A2 as a Potential Link between Type 2 Diabetes and Cancer
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6348
Beyond image: evaluating the perceived effectiveness of workplace mental health programs in the insurance sector
Published 2025-01-01“…Methods A qualitative study used 30 semi-structured interviews with individuals from large insurance companies in Portugal. …”
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6349
Nitrous oxide exerts rewarding effect via regulating D1 receptor and BDNF pathway in ventral tegmental area-nucleus accumbens dopamine circuit
Published 2025-01-01“…This study aimed to examine its rewarding effect and the underlying mechanisms. The exposure of mice to a subanesthetic concentration (20%) of N2O for 30 min for 4 consecutive days paired with N2O in the morning and paired with the air in the afternoon produced apparent rewarding behavior in the conditioned place preference (CPP) paradigm. …”
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6350
A Comparative Study between outcome of 25% glucose in glycerin and submucosal human placental extract injection in the management of Primary Atrophic Rhinitis
Published 2025-02-01“…Progressive atrophy of nasal mucosa and underlying turbinates, formation of scanty viscid secretion and crusts causing foul odor are the cardinal features of this disease. …”
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Identifying mechanisms that shape the food environment in long-term healthcare facilities in the Netherlands: a participatory system dynamics approach
Published 2025-01-01“…Conclusions This study gained a comprehensive, collectively acknowledged understanding of the system dynamics underlying the food environment in Dutch long-term healthcare institutions. …”
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La gestion de l’eau à Bibracte (Saône-et-Loire), avant et après la Conquête romaine
Published 2020-12-01“…It covered a surface of 30 m2. Dated to the beginning of the 1st c. BC, it was also built of stone (quadrangular and irregular-shaped blocks) and waterproofed with clay (the bottom and the foundation trench). …”
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Developing a translational research framework for MDD: combining biomolecular mechanisms with a spiraling risk factor model
Published 2025-01-01“…ObjectiveThe global incidence and burden of Major Depressive Disorder (MDD) are increasing annually, with current antidepressant treatments proving ineffective for 30-40% of patients. Biomolecular mechanisms within the microbiota-gut-brain axis (MGBA) may significantly contribute to MDD, potentially paving the way for novel treatment approaches. …”
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Iranian Pediatric COVID-19 Epidemiology and Clinical Characteristics
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6358
Multi-omics analyses identify gut microbiota-fecal metabolites-brain-cognition pathways in the Alzheimer’s disease continuum
Published 2025-02-01“…Abstract Background Gut microbiota dysbiosis is linked to Alzheimer’s disease (AD), but our understanding of the molecular and neuropathological bases underlying such association remains fragmentary. Methods Using 16S rDNA amplicon sequencing, untargeted metabolomics, and multi-modal magnetic resonance imaging, we examined group differences in gut microbiome, fecal metabolome, neuroimaging measures, and cognitive variables across 30 patients with AD, 75 individuals with mild cognitive impairment (MCI), and 61 healthy controls (HC). …”
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A long‐term study on food choices and nutritional goals of a leaf‐eating primate
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6360
Efficacy and compatibility mechanism of bear bile powder in Shexiang Tongxin dropping pills for acute myocardial infarction treatment
Published 2025-01-01“…Additionally, the combination treatment induced a 62.34% gene reversion rate compared with 55.56% for BBP and 30.20% for CF treatment alone. Modulation of endothelin 1 and growth factor receptor-bound protein 2 was identified as a key synergistic mechanism underlying the anti-AMI effects of BBP in STDP. …”
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